Clinical trials: Subfertility
Subfertility
Letrozole in Stimulated IVF Cycles
In-vitro fertilization (IVF) is the treatment of choice for couples with prolonged infertility. The treatment usually involves hormonal stimulation of the ovaries by follicle stimulating hormone (FSH), followed by surgical…
- Trial name
- NCT02912988
- Testing
- Letrozole
- Where
- 2 sites in China
- Volunteers
- 900 people
- Sponsor
- The University of Hong Kong
Subfertility
Effect of Intralipid Infusion in Patients With Recurrent Implantation Failure
The aim of present study is to evaluate the effect of intralipid 20% infusion, once between days 4 and 9 of the ovarian stimulation, and again within 7 days of a positive pregnancy test on clinical pregnancy rates in women with…
- Trial name
- NCT02865785
- Testing
- Intralipid 20%
- Where
- Egypt
- Volunteers
- 320 people
- Sponsor
- Ain Shams University
Subfertility
A RCT on the Effect of Endometrial Injury on Improving Ongoing Pregnancy Rate in Subfertile Women Undergoing FET Cycles
This is a randomised controlled trial on the effect of endometrial injury in the cycle preceding the frozen-thawed embryo transfer (FET) cycles.
- Trial name
- NCT02197832
- Testing
- Endometrial biopsy, control procedure, Pipelle catheter (Pipelle de Cornier, Laboratoire C.C.D., France)
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- The University of Hong Kong
Subfertility
Hormonal Stimulation in IUI Treatment: Is Clomifen Combined With Ethinyl Estradiol Better, Worse or Equal to Menopur
What is the best medication for hormonal stimulation in cycles with high intra-uterine insemination: tablets of Clomifen (5 days) followed by tablets of Ethinyl Estradiol (5 days) or daily injections with Human Menopausal…
- Trial name
- NCT01569945
- Testing
- Clomifen, Ethinyl Estradiol, Menotropins
- Where
- Belgium
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Infertility
What is the Best Preparation for Embryo Transfer in Cryo Cycles: a Natural Cycle or Light Hormonal Stimulation?
The study investigates if, among women with a regular cycle (between 25 and 45 days), the endometrium is better prepared for the transfer of an embryo that was cryopreserved and if the subsequent embryo implantation rate is…
- Trial name
- NCT00492934
- Testing
- human menopausal gonadotrophins
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Subfertility
Prognostic Value of Progesterone for In Vitro Fertilization (IVF) Outcome
This observational study attempts to investigate the potential role of serum progesterone levels on the day of hCG administration (thus, the end of the follicular phase) on the probability of pregnancy, in patients undergoing IVF…
- Trial name
- PROG2 (NCT01067664)
- Where
- Greece
- Volunteers
- 130 people
- Sponsor
- Aristotle University Of Thessaloniki
Subfertility
LH/HCG Receptor Expression and Retrieval Rates
The purpose of this study is to evaluate if there is an association between the serum LH receptor expression on the day of hCG administration or the day of oocyte retrieval and the retrieval rates at oocyte pick up
- Trial name
- NCT00438373
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Aristotle University Of Thessaloniki
Subfertility
Day 3 Fresh Transfer Followed by Day 3 or Day 5 Vitrification of Supernumerary Embryos
This monocenter academic study aims to evaluate the effectiveness and cost effectiveness of two different strategies: fresh Embryo Transfer (ET) on day 3 followed by cryopreservation of cleavage-stage (Day 3) embryos versus…
- Trial name
- NCT04196036
- Testing
- Day of vitrification
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Sophie Debrock
Subfertility, Female
Effect of Sildenafil Citrate Compared to Estrogen as Adjuvant Therapy for Unexplained Infertility
. This study aimed to determine and compare the effect of vaginal sildenafil citrate and estradiol valerate on endometrial thickness, blood flow and pregnancy rates in infertile women.
- Trial name
- NCT05753098
- Testing
- estrogen therapy, Sildenafil, Clomiphene Citrate 50mg
- Where
- Egypt
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Subfertility
Oral Dydrogesterone as Luteal Phase Support in Natural Cycle FET
This randomised double-blinded controlled trial aims to compare the live birth rate in natural FET cycles with and without oral dydrogesterone as luteal phase support.
- Trial name
- NCT03859921
- Testing
- Dydrogesterone
- Where
- China
- Volunteers
- 716 people
- Sponsor
- The University of Hong Kong
Subfertility, Female
A Cross Sectional Evaluation of Vitamin D Status and Ovarian Reserve Markers
Evaluation of the association between vitamin D (VD) deficiency and ovarian reserve markers in a group of Pakistani sub fertile women was conducted
- Trial name
- NCT05137964
- Testing
- Vitamin D
- Volunteers
- 199 people
- Sponsor
- Australian Concept Medical Center
Subfertility
Dehydroepiandrosterone Versus Growth Hormone in Women Undergoing ICSI With Expected Poor Ovarian Response
300 women with expected poor ovarian response (POR) undergoing in vitro fertilization or intra-cytoplasmic sperm injection (ICSI) will be randomly divided into 2 equal groups using computer generated random numbers.
- Trial name
- NCT02736591
- Testing
- DHEA, Growth Hormone-Releasing Hormone
- Where
- 2 sites in Egypt
- Volunteers
- 210 people
- Sponsor
- Cairo University
Infertility, Reproductive Sterility
Does in Vivo Culture of Pre-cleavage Stage Embryo Reduce the Incidence of Aneuploidy?
This Clinical Study has been designed to assess and compare the impact of in vitro or in vivo culture conditions on the euploidy of sibling blastocysts.
- Trial name
- NCT02652143
- Testing
- AneVivo (Medical device for in vivo culture of embryos), comparator for embryo culture in vitro
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Anecova SA
Subfertility
Endometrial Scratching in Couples With Unexplained Subfertility
Endometrial scratching in luteal phase of a spontaneous menstrual cycle may increase pregnancy rate in women with unexplained infertility.
- Trial name
- ESUS (NCT01412606)
- Testing
- scratching
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Mansoura University
Subfertility, Pregnancy
A RCT Comparing Spontaneous Natural Cycles and Human Chorionic Gonadotrophin-induced Natural Cycles in FET
This is a randomized controlled trial on the comparison of the ongoing pregnancy rate in frozen-thawed embryo transfer cycles with spontaneous ovulation and hCG-induced natural cycles.
- Trial name
- NCT02197208
- Testing
- Daily monitoring of LH and E2, hCG induced natural cycle, ultrasound
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 300 people
- Sponsor
- The University of Hong Kong
Subfertility
Why Subfertile Couples Drop Out
Dropout rates for fertility treatments are high. This study will examine the rate of patients that drop out during any type of subfertility work up or treatment.
- Trial name
- DOT (NCT02302781)
- Testing
- Questionnaires
- Where
- 7 sites in Netherlands
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Isala
Subfertility
Endometrial Scratching for Cryopreserved Embryo Transfer
Endometrial injury performed in a cycle preceding the one for embryo transfer is associated with an increased implantation and pregnancy rate when carried out during the month preceding that of ovulation induction and fresh…
- Trial name
- NCT02093442
- Testing
- Endometrial injury
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- University of Sao Paulo
Subfertility
Evaluation of the Role of Follicular Sensitivity Index in the Prediction of IVF/ICSI Outcome
Records of women who had in vitro fertilization (IVF) or intra-cytoplasmic sperm injection (ICSI) in Dar AlTeb sub-fertility center will be reviewed and the follicular sensitivity index (FSI) will be calculated and correlated…
- Trial name
- NCT02317978
- Testing
- ICSI
- Where
- Egypt
- Volunteers
- 10,000 people
- Sponsor
- Cairo University
Male Subfertility, Oligospermia
7 NUTS Study. Diet Modification and Male Fertility.
Setting. Outpatient fertility clinic. Aim. Investigate if a modification in nutritional habits may improve in the short term the qualities of human sperm, testing two hypothesis: i) that adding to the diet a natural whole food…
- Conditions
- Male Subfertility, Oligospermia, Asthenospermia, Teratospermia
- Trial name
- NCT02063256
- Testing
- 7 nuts a day, Diet modification
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Subfertility
Does Dehydro Epiandrosterone (DHEA) Improve Pregnancy Rate in Women Undergoing IVF/ICSI With Expected Poor Ovarian Response?
140 women with expected poor ovarian response undergoing IVF/ICSI will be randomly divided into 2 groups using computer generated random numbers .
- Trial name
- NCT02151006
- Testing
- DHEA
- Where
- 2 sites in Egypt
- Volunteers
- 140 people
- Sponsor
- Cairo University