Clinical trials: Submucosal Tumor
Barrett's Esophagus
Application of hybridAPC in the Treatment of Barrett
The purpose of this study is to evaluate the efficacy and safety of the new technique of HybridAPC in the treatment of Barrett.
- Trial name
- NCT03418584
- Testing
- HybridAPC
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Changhai Hospital
Rectal Neuroendocrine Tumors
Modified Double Snare Assisted EMR (mDS-EMR) VS ESD for Rectal Neuroendocrine Tumors Smaller Than 1cm
The aim of this study is evaluating and safety and efficacy between the modified double snare EMR and ESD. It is intended to prove that for rectal neuroendocrine tumors within 1 cm, the complete resection rate of the mDS-EMR is…
- Trial name
- NCT07373015
- Testing
- modified double snare assisted endoscopic mucosal resection, endoscopic submucosal dissection
- Volunteers
- 118 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Duodenal Adenoma, Duodenal Carcinoma
Analysis of Long-term Outcomes of Endoscopic Resection of Duodenal and Ampullary Mucosal and Submucosal Lesions
Mucosal and submucosal lesions of the duodenum represent a diverse group of pathologies, ranging from benign adenomas to lesions with significant malignant potential.
- Conditions
- Duodenal Adenoma, Duodenal Carcinoma, Papillary Adenoma, Papillary Adenocarcinoma
- Trial name
- DuoP-ER (NCT07781137)
- Where
- Australia
- Volunteers
- 1,000 people
- Sponsor
- Western Sydney Local Health District
Superficial Esophageal Cancers
Status of Superficial Esophageal Cancers Treated by Endoscopy "OESOFARE"
In 2013, esophageal cancer was the 9th cause of cancer in the world and the 6th in terms of cancer mortality. The prognosis of this cancer varies according to geographical areas, but in Europe and the USA, the 5-year survival…
- Trial name
- OESOFARE (NCT03674801)
- Where
- France
- Volunteers
- 151 people
- Sponsor
- Nantes University Hospital
Digestive System Diseases
Endoscopic Submucosal Dissection for Gastrointestinal Neoplasms
Endoscopic submucosal dissection (ESD) is a newly developed technique in the field of endoscopic treatment for GI neoplasms, because of its high rate of en bloc resection.
- Trial name
- NCT01378507
- Testing
- endoscopic submucosal dissection
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Chinese PLA General Hospital
Upper Gastrointestinal Submucosal Tumors (SMTs), Gastrointestinal Stromal Tumors (GISTs)
ESTD vs. VATS for Upper Gastrointestinal Submucosal Tumors
The purpose of this study is to determine the efficacy and safety of endoscopic submucosal tunnel dissection (ESTD) compared with video-assisted thoracoscopic surgery (VATS) in the treatment of upper gastrointestinal submucosal…
- Conditions
- Upper Gastrointestinal Submucosal Tumors (SMTs), Gastrointestinal Stromal Tumors (GISTs), Leiomyoma
- Trial name
- NCT01768104
- Testing
- ESTD, VATS
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Gastrointestinal Submucosal Tumors
Evaluation of Short-term and Long-term Efficacy of Endoscopic Treatment for Gastrointestinal Submucosal Tumors
This study aims to comprehensively assess how well endoscopic treatments work for gastrointestinal submucosal tumors (SMTs)-both in the short term right after treatment and over the long run-and to figure out what factors might…
- Trial name
- NCT07353346
- Volunteers
- 700 people
- Sponsor
- Xijing Hospital
Fibroid
Ulipristal Acetate Versus GnRH Analogue and Myometrial Preservation
Submucosal fibroid grow inside the uterine cavity and are associated with menorrhagia, abnormal uterine bleeding (AUB) and infertility.
- Trial name
- NCT02357563
- Testing
- ulipristal acetate, Leuprolide acetate
- Where
- Italy
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Leiomyoma, Uterine Fibroids
Safety and Effectiveness Study of RF Ablation of Uterine Fibroids to Reduce Menstrual Bleeding: the Fibroid Ablation Study
The primary objective of this study is to test the hypothesis that a minimum 75% volume radiofrequency ablation of fibroids associated with menorrhagia results in reduction of menstrual bleeding.
- Conditions
- Leiomyoma, Uterine Fibroids, Menorrhagia
- Trial name
- FAST (NCT00768742)
- Testing
- VizAblate Intrauterine Ultrasound-Guided RF Ablation
- Where
- 3 sites in Canada
- Sponsor
- Gynesonics
Robot Surgery, Endoscopic Submucosal Dissection (ESD)
Efficacy and Safety of Robot-assisted Endoscopic Submucosal Dissection for Colorectal Neoplasm
The objective of this study is to investigate the role of the flexible auxiliary single-arm transluminal endoscopic robot (FASTER) system in colorectal endoscopic submucosal dissection (ESD) and to validate its superiority over…
- Conditions
- Robot Surgery, Endoscopic Submucosal Dissection (ESD), Colorectal Neoplasms
- Trial name
- NCT06973083
- Testing
- FASTER-assisted ESD, Conventional ESD
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Shandong University
Gastric Polyps, Intestinal Polyps
Recurrence After Gastric and Intestinal Polyp Resection
This is a retrospective and prospective cohort study designed to evaluate the recurrence rate and identify risk factors after endoscopic resection of gastric and intestinal polyps.
- Conditions
- Gastric Polyps, Intestinal Polyps, Colon Polyps, Colorectal Polyps
- Trial name
- RAGIP (NCT07314554)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- LanZhou University
Pancreatic Disease, Pancreatic Cancer
EUS Examination Using EndoSound Vision System vs. Standard Echoendoscope
This is a randomized trial to compare the standard echoendoscope with the newly developed EndoSound Visual System in the evaluation of lesions in the gastrointestinal tract.
- Conditions
- Pancreatic Disease, Pancreatic Cancer, Pancreatic Cyst, Gastrointestinal Tumor
- Trial name
- NCT06340620
- Testing
- Endoscopic ultrasound examination
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Orlando Health, Inc.
Small Size Gastrointestinal Stromal Tumors, GIST
RCT of EFTR Versus STER for GIST Treatment
Endoscopic resection has been increasing utilized as the treatment for small size gastrointestinal stromal tumors (GIST), of which the best resection method has not been identified.
- Trial name
- NCT07411118
- Testing
- Endoscopic full thickness resection (EFTR) / Exposed non-tunneling EFTR, Submucosal Tunneling Endoscopic Resection (STER) / Exposed tunneling EFTR
- Where
- 4 sites in China, Hong Kong and 2 more
- Volunteers
- 136 people
- Sponsor
- Chinese University of Hong Kong
GIST
Long Outcome of Endoscopic Submucosal Dissection for Small Gastrointestinal Stromal Tumors (<2cm)
Data are currently insufficient to guide the management of very small gastrointestinal stromal tumors（GISTs）（< 2 cm) discovered incidentally on endoscopy,this study is designed to collect the medical records of patients in…
- Trial name
- NCT03082079
- Testing
- ESD
- Volunteers
- 90 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Gastric Cancer, Gastric Adenoma
The Efficacy of Topical Bupivacaine and Triamcinolone Acetonide Injection in the Relief of Pain After Endoscopic Submucosal Dissection for Gastric Neoplasia: A Randomized Double-blind, Placebo-controlled Trial
Although pain is a common complication of endoscopic submucosal dissection (ESD), management strategies are inadequate. bupivacaine is used for visceral pain control in chronic pain and in pain associated with surgery in clinical…
- Trial name
- NCT01961752
- Testing
- Saline, Bupivacaine + saline, Bupivacaine + triamcinolone acetonide
- Where
- South Korea
- Volunteers
- 111 people
- Sponsor
- Yonsei University
Ampulla of Vater Adenoma
Comparison on the Efficacy of Endoscopic Snare Papillectomy With or Without Submucosal Injection
Because the ampulla of Vater is strategically located at the confluence of the pancreatic and common bile ducts, endoscopic resection of papillary neoplasms may be technically different from endoscopic mucosal resection in other…
- Trial name
- NCT02165852
- Testing
- Papillectomy without injection, Papillectomy with injection
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Soon Chun Hyang University
Esophageal Carcinoma in Situ AJCC V7
A Comparative Study of Endoscopic Submucosal Dissection and Photodynamic Therapy for Early Esophageal Cancer
The purpose of this study was to compare the efficacy and safety of Photodynamic therapy (PDT) and Endoscopic submucosal (ESD) dissection in the treatment of early esophageal cancer.
- Trial name
- NCT05208775
- Testing
- PDT, ESD
- Volunteers
- 46 people
- Sponsor
- The First Affiliated Hospital of Henan University of Science and Technology
Rectal Neuroendocrine Tumor
Underwater Endoscopic Mucosal Resection Versus Endoscopic Submucosal Dissection for the Treatment of Small Rectal Neuroendocrine Tumors
Underwater endoscopic mucosal resection (UEMR) and endoscopic submucosal dissection (ESD) have both been reported to be two effective treatment methods for small rectal neuroendocrine tumor (NET).
- Trial name
- NCT07759960
- Testing
- UEMR procedure, ESD procedure
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Esophageal Cancer
Endoscopic Ultrasound Plus Submucosal Injection for Early Esophageal Cancer
Preoperative accurately staging T1a or T1b in early esophageal cancer is vital for the choices of treatment. At present, the main diagnostic method for early esophageal cancer is endoscopic ultrasound (EUS).
- Trial name
- NCT01555801
- Testing
- submucosal injection needle ; EUS, ordinary endosonography(EUS)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sun Yat-sen University
Submucosal Tumor, Gastrointestinal Stromal Tumor (GIST)
CEH-EUS for Differentiating GISTs and Leiomyomas: A Multicenter Prospective Self-Controlled Study
The investigators conduct a prospective, multicenter diagnostic trial primarily aimed at evaluating the value of contrast-enhanced harmonic endoscopic ultrasound (CEH-EUS) in differentiating gastrointestinal stromal tumors…
- Conditions
- Submucosal Tumor, Gastrointestinal Stromal Tumor (GIST), Leiomyoma
- Trial name
- NCT07106411
- Testing
- Endoscopic Ultrasound, Contrast-Enhanced Harmonic Endoscopic Ultrasound (CEH-EUS)
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Huazhong University of Science and Technology