Clinical trials: Substance Use Disorders (SUD), active
Substance Abuse, Substance Addiction
The Trans-Led Care Study
This study is testing a new mutual-help group called "the TLC program" for transgender adults who use substances or are recently in recovery.
- Conditions
- Substance Abuse, Substance Addiction, Substance Use Disorder (SUD), Substance Use (Drugs, Alcohol)
- Trial name
- TLC (NCT06880705)
- Testing
- The TLC Program
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Illinois Institute of Technology
Substance Use Disorder (SUD)
Recovery Works - Facilitating Sustainable Recovery Through Workforce
The goal of this clinical trial is to determine whether an apprenticeship-based workforce model, the Community Restitution Apprenticeship-Focused Training (CRAFT), improves recovery outcomes for persons with substance use…
- Trial name
- NCT07216612
- Testing
- Community Restitution Apprenticeship-Focused Training (CRAFT), Standard Employment Model
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- West Virginia School of Osteopathic Medicine
Internalizing Disorders, Substance Use Disorders
Family Support Protocol for Adolescent Internalizing Disorders
This R34 will develop and test an adjunctive treatment protocol for addressing co-occurring internalizing disorders among adolescents enrolled in usual care for substance use problems.
- Trial name
- Fam-AID (NCT06413979)
- Testing
- Family Support Protocol for Adolescent Internalizing Disorders (Fam-AID)
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- The National Center on Addiction and Substance Abuse at Columbia University
Posttraumatic Stress Disorder (PTSD), Substance Use Disorder (SUD)
The Many Roads to Trauma Recovery: A Clinical Trial Comparing Empirically Supported Treatments for Veterans With Co-Morbid Posttraumatic Stress and Substance Use Disorder Symptoms
Veterans with co-morbid posttraumatic stress disorder (PTSD) and substance use disorders (SUDs) are at substantial risk of developing hypertension and cardiovascular diseases that often lead to premature death, with some evidence…
- Trial name
- NCT07756723
- Testing
- Trauma Informed Heart Rate Variability Biofeedback, Present Centered Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Coatesville VA Medical Center
Substance Use Disorders, Substance Use
Examining Feasibility and Acceptability of Telemedicine for Substance Use Disorder (SUD)
The objective of this pilot intervention study is to iteratively refine motivational interviewing and psychosocial intervention programs delivered via telehealth (Teletx) to help improve substance use and other related outcomes…
- Conditions
- Substance Use Disorders, Substance Use, Substance Dependence
- Trial name
- NCT04768920
- Testing
- MI-CBT Teletx
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Substance Use Disorder (SUD)
Predicting Dropout and Outcome From Neuropsychological Functions in SUD Patients
The aim of this project is to gain a more specific understanding of how different cognitive profiles predict residential treatment drop-out, treatment retention and post-treatment outcome in a population with Substance Use…
- Trial name
- NCT03220373
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
PTSD - Post Traumatic Stress Disorder, Substance Use Disorder (SUD)
Mechanisms of Written Exposure Therapy in Residential SUD Treatment
The goal of this clinical trial is to learn how Written Exposure Therapy (WET), a brief treatment for PTSD, works among individuals with substance use disorders (SUD) engaged in residential SUD treatment and how biology may…
- Trial name
- NCT07397507
- Testing
- Written Exposure Therapy, Neutral Writing
- Volunteers
- 108 people
- Sponsor
- Mclean Hospital
Posttraumatic Stress Disorder (PTSD), Substance Use Disorder (SUD)
Written Exposure in Substance Treatment (WEST 3.0): Randomized Controlled Trial
The purpose of the current research study is to evaluate the efficacy of the refined Written Exposure in Substance Treatment (WEST) for PTSD among residential SUD patients through a randomized controlled trial.
- Trial name
- WEST (NCT07782268)
- Testing
- Written Exposure Therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Potomac Health Foundations
Trauma and Stress-related Disorders, Substance Use Disorder (SUD)
Protocol Study on Addiction, Trauma and Immigration Among Vulnerable Young Adults in Grand Est
The ATICC study (Addiction, Trauma, and Immigration, Prevention and Cross-Cultural Support for Care) investigates the complex relationships between trauma, substance use, migration experiences, and mental health perceptions among…
- Conditions
- Trauma and Stress-related Disorders, Substance Use Disorder (SUD), Substance Use Risk
- Trial name
- ATICC (NCT06922721)
- Testing
- Focus group
- Where
- 7 sites in France
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of Lorraine
Substance Use Disorder (SUD), Drug Overdose
Justice Community Overdose Innovation Network II TCU Hub
The current study proposes to use a Hybrid Type 3 implementation research strategy to: 1) Significantly enhance our understanding of public health outcomes [e.g., overdose incidents and substance-use (SU)-related Emergency…
- Conditions
- Substance Use Disorder (SUD), Drug Overdose, Criminal Behavior
- Trial name
- JCOIN II TCU (NCT07528846)
- Testing
- Core-interagency community engagement approach, Enhanced-Core plus community engagement specialist
- Where
- United States
- Volunteers
- 1,620 people, healthy volunteers welcome
- Sponsor
- Texas Christian University
Bipolar Disorder
Senyo Health App - Comorbid Alcohol Use Disorder Treatment in Individuals With Bipolar Disorder Using a Telehealth Collaborative Care Platform
The purpose of this study is to examine the effectiveness of a digital integrated behavioral health (IBH) platform in improving alcohol use outcomes, including treatment retention and substance use frequency and severity in…
- Trial name
- NCT07556861
- Testing
- Senyo Health App
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Substance Use Disorder (SUD), Anxiety
Behavioral Rigidity in Residential Treatment for Substance Use Disorder (RIG-TD)
Behavioral rigidity, the tendency to maintain inflexible patterns of thinking and acting despite changing circumstances, is a common feature in substance use disorders, depression, and anxiety.
- Conditions
- Substance Use Disorder (SUD), Anxiety, Depression Anxiety Disorder
- Trial name
- RIG-TD (NCT07590115)
- Testing
- No intervention
- Where
- Mexico
- Volunteers
- 35 people
- Sponsor
- Lauro Gutiérrez Castro
Substance Use Disorders (SUD), Pregnancy
Culturally Engaged REcovery: MOms Connected Through Native communitY
Pregnant and postpartum American Indian and Alaska Native people (Native mothers) face a more than two-fold higher risk of maternal mortality compared to non-Hispanic White mothers.
- Conditions
- Substance Use Disorders (SUD), Pregnancy, Maternal Morbidity and Mortality, Cultural Adaptation
- Trial name
- CEREMONY (NCT06747442)
- Testing
- Cradleboard Journey
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of Utah
Severe Mental Illness, Substance Use Disorder (SUD)
A Study to Investigate Health Related Quality of Life With a Pharmacist Intervention Compared to Treatment as Usual in Participants With Severe Mental Illness and Substance Use Disorder Receiving Treatment From FACT Teams.
The study aims to evaluate the impact of integrating a clinical pharmacist into Flexible Assertive Community (FACT) teams on health-related quality of life and pharmacotherapy for individuals with severe mental illness and…
- Trial name
- pharmaFACT (NCT07597863)
- Testing
- Clinical Pharmacist Intervention
- Where
- Norway
- Volunteers
- 160 people
- Sponsor
- Sykehuset Innlandet HF
Substance Use Disorder (SUD)
Effect of Person-Centered Occupational Therapy Interventions for Substance Use Disorder
This study investigates the impact of person-centered occupational therapy interventions on individuals diagnosed with substance use disorder.
- Trial name
- NCT07364240
- Testing
- Awareness Training, Person-Centered Occupational Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Hacettepe University
PTSD, Substance Use Disorder (SUD)
Adolescent Stress and Substance Intervention Subsequent to Trauma
The long-term goal of this study is to address the adoption of the new trauma center requirement to establish best practices of screening for acute stress with an intervention to prevent both adolescent PTSD and substance use.
- Conditions
- PTSD, Substance Use Disorder (SUD), Acute Stress Disorder
- Trial name
- ASSIST (NCT07197476)
- Testing
- ASSIST Video Intervention
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Substance Use Disorder
A Type I Hybrid Effectiveness-Implementation Trial of MIO
Mothers with substance use disorders face unprecedented stress in their roles as parents working to care for their children while maintaining healthy recovery.
- Trial name
- NCT07168642
- Testing
- Mothering from the Inside Out
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Baystate Medical Center
Substance Use Disorder (SUD), Addiction
NLP Analysis of Weekly Narratives for Dynamic Clinical Assessment in SUD
This prospective observational study follows adults undergoing residential rehabilitation for severe substance use disorders at a specialized treatment center in Mexico.
- Conditions
- Substance Use Disorder (SUD), Addiction, Anxiety, Emotional Dysregulation
- Trial name
- DYNA-NLP (NCT07595614)
- Testing
- Residential rehabilitation as usual
- Where
- Mexico
- Volunteers
- 35 people
- Sponsor
- Lauro Gutiérrez Castro
Mental Health Issue, Substance Use Disorders
Improving Maternal Mental Health & SUD Screening and Treatment
The purpose of the study is to compare a text message-based mental health and substance use screening and referral to a treatment program, called Listening to Women and Pregnant and Postpartum People (LTWP), to standard of care…
- Conditions
- Mental Health Issue, Substance Use Disorders, Postpartum Depression, Postpartum Anxiety
- Trial name
- NCT05764213
- Testing
- Listening to Women & Pregnant and Postpartum People
- Where
- United States
- Volunteers
- 10,469 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Substance Use Disorder (SUD), Opioid Use Disorder
Disease Intervention Specialist (DIS) for SUD
This prospective observational study evaluates three Disease Intervention Specialist service models designed to proactively identify and support adults at risk for substance use disorder.
- Conditions
- Substance Use Disorder (SUD), Opioid Use Disorder, Alcohol Use Disorder (AUD), Drug Use
- Trial name
- DIS-SUD (NCT07875361)
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Ohio State University