Clinical trials: Substance-Related Disorder
Tobacco Dependence, Cardiovascular Diseases
Physical Activity as an Aid for Smoking Cessation
Including a tailored moderate-intensity physical activity intervention in a standard smoking cessation treatment program (pharmaceutical treatment and counseling) increases the chances of quitting and reduces nicotine withdrawal…
- Conditions
- Tobacco Dependence, Cardiovascular Diseases, Physical Activity
- Trial name
- PHASMO (NCT00521391)
- Testing
- Allez Hop
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Alcohol Use Disorder
New Relapse Model in Psychiatry
The goal of this clinical trial is to learn about risk factors of relapse in patients with alcohol use disorder. The main questions it aims to answer are : Among patients with Alcohol Use Disorder, are there clusters of patients…
- Trial name
- NRMP (NCT06244641)
- Testing
- Auto-questionnaires, hetero-questionnaires and Evoked-potentials
- Where
- Belgium
- Volunteers
- 350 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Cocaine Dependence, Methamphetamine Dependence
Smoking-Cessation and Stimulant Treatment (S-CAST)
The primary objective of this study is to evaluate the impact of substance-abuse treatment as usual plus smoking-cessation treatment (TAU+SCT), relative to substance-abuse treatment as usual (TAU), on drug-abuse outcomes.
- Conditions
- Cocaine Dependence, Methamphetamine Dependence, Nicotine Dependence
- Trial name
- S-CAST (NCT01077024)
- Testing
- Smoking-cessation treatment
- Where
- 12 sites in United States
- Volunteers
- 538 people
- Sponsor
- University of Cincinnati
Cocaine-Related Disorders, Opioid-Related Disorders
Fluoxetine to Reduce Cocaine Use in Cocaine and Opioid Addicts
Cocaine addiction is a serious health problem with no available medical treatment for preventing relapse. Fluoxetine, a medication that is currently used to treat depression and anxiety disorders, may also be effective at…
- Trial name
- NCT00142779
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Neonatal Abstinence Syndrome
Morphine Versus Methadone for Opiate Exposed Infants With Neonatal Abstinence Syndrome
This study investigates the use of methadone versus morphine wean for the treatment of neonatal abstinence syndrome for infants exposed to opioids in utero.
- Trial name
- NCT02851303
- Testing
- Morphine, Methadone
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of New Mexico
Cocaine-Related Disorders
Rapid Evaluation of Baclofen for Treatment of Cocaine Abuse/Dependence - 6
The purpose of this study is to empirically test a series of medications to: 1) determine each medication's efficacy in treatment of cocaine abuse/dependence; 2) find most effective dose range for each medication.
- Trial name
- NCT00000303
- Testing
- Baclofen
- Where
- United States
- Sponsor
- University of California, Los Angeles
College Drinking
Text-based Alcohol Prevention for First Year College Students
This project aims to combat excessive perceived norms that contribute to high volume drinking by young adults, which adversely affects health and academic achievement.
- Trial name
- NCT03864237
- Testing
- Alcohol texts, Attention control
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Brown University
Tobacco Dependence, Tobacco Smoking
Smoke-free Home Study in Subsidized Housing
Comprehensive smoke-free policies have the potential to substantially reduce tobacco-related disparities among populations in subsidized housing.
- Trial name
- NCT06170437
- Testing
- Smoke-free home resident intervention, Lay Health Worker coaching
- Where
- United States
- Volunteers
- 544 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Substance Abuse, HIV Risk
Jail-Based Impact of Crime Intervention
The purpose of this study is to evaluate whether the Impact of Crime (IOC) group intervention with jail inmates reduces post-release recidivism, substance abuse, and HIV risk behavior.
- Conditions
- Substance Abuse, HIV Risk, Criminogenic Thinking, Shame
- Trial name
- IOC (NCT01378936)
- Testing
- MI plus IOC group intervention, Motivational Interview only
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- George Mason University
Food Effect
Study to Assess Food Effect on Sativex Bioavailability
Study to assess effect of food on the bioavailability of a single dose of Sativex and to measure its' pharmacokinetics after a single and multiple doses.
- Trial name
- NCT01322464
- Testing
- Sativex
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Jazz Pharmaceuticals
Smoking Cessation
Smokers' Quitline for Asian Language Speakers
The study tested the effects of telephone counseling for smokers from three Asian language speaking groups: Chinese, Korean, and Vietnamese.
- Trial name
- NCT01248832
- Testing
- Telephone Counseling, Self-Help Materials
- Where
- United States
- Volunteers
- 2,277 people
- Sponsor
- University of California, San Diego
Nicotine Dependence
Effects of Progesterone on Smoked Nicotine Induced Changes in Hormones and Subjective Ratings of Stimulant Drug Effects
The clinical studies propose to study the abuse-related effects of nicotine after progesterone administration during the follicular phase in women of reproductive age.
- Trial name
- NCT01636336
- Testing
- Nicotine, Progesterone
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Diabetes, Cardiovascular Disease
Reverse Innovation and Patient Engagement to Improve Quality of Care and Patient Outcomes
Project CONNECT ("Community-based Organizations Neighborhood Network: Enhancing Capacity Together") is a randomized controlled trial that involves 22 community-based organizations (CBOs) located in Baltimore, MD.
- Conditions
- Diabetes, Cardiovascular Disease, Substance Abuse Disorder, Mental Health Disorder
- Trial name
- CONNECT (NCT02222909)
- Testing
- Co-developed IT intervention
- Where
- United States
- Volunteers
- 6,767 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Trauma and Stress-related Disorders, Substance Use Disorder (SUD)
Protocol Study on Addiction, Trauma and Immigration Among Vulnerable Young Adults in Grand Est
The ATICC study (Addiction, Trauma, and Immigration, Prevention and Cross-Cultural Support for Care) investigates the complex relationships between trauma, substance use, migration experiences, and mental health perceptions among…
- Conditions
- Trauma and Stress-related Disorders, Substance Use Disorder (SUD), Substance Use Risk
- Trial name
- ATICC (NCT06922721)
- Testing
- Focus group
- Where
- 7 sites in France
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of Lorraine
Narcotic Use, Postoperative Pain
A Prospective Assessment of Opioid Utilization Post-operatively in Sports Orthopaedic Surgeries
There was a study titled "A prospective evaluation of opioid utilization after upper extremity surgical procedures: Identifying consumption patterns and determining prescribing guidelines" by Dr.
- Conditions
- Narcotic Use, Postoperative Pain, Narcotic Abuse, Opioid Use
- Trial name
- Opioids (NCT03422211)
- Testing
- Questionnaire
- Where
- 3 sites in United States
- Volunteers
- 223 people
- Sponsor
- St. Louis University
Healthy Subjects
An Study to Evaluate the Effects of Fluconazole on the Pharmacokinetics (PK) of Sativex® in Healthy Subjects With Cannabis Experience.
The study aims to evaluate the effect of fluconazole on the pharmacokinetic (PK) profile of a single oromucosal dose of Sativex® (i.e.
- Trial name
- NCT02325011
- Testing
- Sativex® (Treatment A), Sativex® and fluconazole concomitantly (Treatment B)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Jazz Pharmaceuticals
Preoperative Screen for Substance Abuse in in Patients Undergoing Emergency Operation
Observational Study of Preoperative Screen for Substance Abuse
Substance abuse is a growing problem world wide, and treatment of substance abusers in the perioperative period, especially for emergency operation is challenging.
- Trial name
- NCT02621411
- Testing
- Substance use
- Where
- China
- Volunteers
- 1,031 people
- Sponsor
- West China Hospital
Migraine, Cannabis
Efficacy of Inhaled Cannabis for Acute Migraine Treatment
This crossover study will evaluate 3 different treatments of vaporized cannabis (THC, THC/CBD mix, and CBD) and vaporized placebo cannabis for the acute treatment of migraine.
- Conditions
- Migraine, Cannabis, THC, CBD
- Trial name
- NCT04360044
- Testing
- THC ~5%, CBD ~12%, THC ~5% and CBD ~12%
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of California, San Diego
Opioid-Related Disorders
Trial of Methadone Maintenance Versus Methadone Detox in Jail
Methadone maintenance treatment (MMT) has been shown to be effective in reducing drug use, criminal activity and recidivism. Given this effectiveness, maintaining individuals who are enrolled in community MMT when committed to…
- Trial name
- NCT01874964
- Testing
- Methadone Maintenance, Linkage to methadone maintenance
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- The Miriam Hospital
Substance-Related Disorders
Telephone Enhancement Procedure for Continuing Care - 1
The purpose of this study is to test a feasibility study of a telephone enhancement procedure (TELE) to improve participation in continuing care activities.
- Trial name
- NCT00067171
- Testing
- Behavior Therapy
- Where
- 4 sites in United States
- Volunteers
- 339 people
- Sponsor
- Duke University
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