Clinical trials: Success
Complex Anal Fistula
Success Rate, Continence, and Quality of Life With a Bioprosthetic Plug for Treating Complex Anal Fistula
Anal abscess-fistula disease is of common occurrence and has a significant impact on the quality of life of affected individuals.
- Trial name
- NCT01612195
- Testing
- Anal fistula plug
- Where
- Switzerland
- Volunteers
- 46 people
- Sponsor
- University Hospital, Basel, Switzerland
Infertility
What Embryoselection for What Chance of Success ? EmbryoSelect Study
The aim of the research is to evaluate the results of the first in vitro fertilization (IVF) attempt according to the type of embryo culture.
- Trial name
- EmbryoSelect (NCT04484181)
- Testing
- Embryo culture in time lapse technology (TLT), Embryo culture in conventional incubator
- Where
- 2 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Bordeaux
Overactive Bladder Syndrome
Validation of a Real-time Urodynamic Measure of Urinary Urgency
Urinary urgency is a key symptom of overactive bladder syndrome (OAB) and may be more bothersome to a patient than the symptom of urinary frequency.
- Trial name
- NCT00909428
- Testing
- Solifenacin Succinate
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Loyola University
Laryngeal Edema
Laryngeal Edema Assessment by Cuff Leak Test and Ultrasound in ICU Patients and Its Relationship With Weaning Success
This study evaluates laryngeal edema in ICU patients during weaning from mechanical ventilation. It compares the cuff leak test and ultrasound-based laryngeal air column measurements in predicting weaning success.
- Trial name
- NCT07523828
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Opioid Withdrawal
Combining Pregabalin (LYRICA®) With Lofexidine (LUCEMYRATM) to Treat OPIOID Withdrawal
A phase II double-blind placebo-controlled parallel group clinical trial that will randomize 90 subjects to investigate whether pregabalin (PGB) combined with Lofexidine (LFX) can reduce opioid withdrawal-related subjective…
- Trial name
- PGB-LOF (NCT04218240)
- Testing
- Pregabalin 200 MG capsules, Lofexidine 0.18Mg Tab
- Where
- 3 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Pennsylvania
Surgery, Gynecologic Disease
Study Evaluating the Success Rate of Outpatient Management of the Total Benign Hysterectomy by Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) Compared to Each of the Two Laparoscopic Routes (Conventional and Robot-assisted).
Benign total hysterectomy is one of the most commonly performed gynecological surgery. Conventionally performed by a classical surgical approach, it is now provided routinely and for several years by laparoscopy and more recently…
- Trial name
- HYSTERAMBU (NCT06471049)
- Testing
- Benign Hysterectomy
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Elsan
Stroke, Acute, Blood Pressure
Clevidipine Infusion for Blood Pressure Management After Successful Revascularization in Acute Ischemic Stroke
The CLEVER Study is a prospective, 2-arm, randomized, single-center pilot study to assess the safety and efficacy of intensive blood pressure control using Clevidipine (on-label use) in AIS patients undergoing standard of care…
- Conditions
- Stroke, Acute, Blood Pressure, Mechanical Thrombectomy
- Trial name
- CLEVER (NCT05175547)
- Testing
- Clevidipine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- ProMedica Health System
Teeth, Endodontically-Treated
Application of Photodynamic Therapy and Diode Laser for Endodontic Therapy of Young Permanent Teeth
The pulp necrosis of permanent immature teeth implies the interruption of the root formation and apical closure. Diode lasers have been used in many areas of dentistry, with tendency of good results in canal and dentine…
- Trial name
- NCT03074136
- Testing
- Photodinamic therapy, Diode laser, 0.5% Sodium hypochlorite
- Where
- Serbia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Association of Paediatric and Preventive Dentists of Serbia
HIV Infections
The Safety and Effectiveness of Didanosine Plus Stavudine Plus Delavirdine Mesylate Plus MKC-442 in HIV-Infected Patients Who Have Not Had Success With Protease Inhibitors
The purpose of this study is to see if it is safe and effective to give MKC-442, didanosine (ddI), stavudine (d4T), and delavirdine (DLV) to HIV-positive patients.
- Trial name
- NCT00002420
- Testing
- Emivirine, Hydroxyurea, Delavirdine mesylate
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Bristol-Myers Squibb
Perfusion Index, Peripheral Nerve Block Success
Perfusion Index in the Success of Peripheral Nerve Block
After a successful peripheral nerve block, blockade of sympathetic nerve fibers results in local vasodilatation, increased local blood flow, and increased skin temperature.Increased permeability index; Can be used as a reliable…
- Trial name
- NCT02989896
- Testing
- perfusion index
- Volunteers
- 120 people
- Sponsor
- Erzincan University
Aortic Valve Stenosis
Anticoagulant Versus Dual Antiplatelet Therapy for Preventing Leaflet Thrombosis and Cerebral Embolization After Transcatheter Aortic Valve Replacement
This trial is to compare the efficacy of NOAC(Novel Oral Anticoagulants) with edoxaban vs. dual antiplatelet therapy (DAPT) for prevention of leaflet thrombosis (documented by cardiac CT imaging) and cerebral embolization…
- Trial name
- ADAPT-TAVR (NCT03284827)
- Testing
- NOAC, DAPT
- Where
- 5 sites in Hong Kong, South Korea and 1 more
- Volunteers
- 235 people
- Sponsor
- Duk-Woo Park, MD
Induced; Birth
Value of Measuring Cervical Angle and Length by Ultrasound in Prediction of Successful Induction of Delivery
Seventy ladies indicated for induction of delivery will be recruited. Two ways of assessment of their cervices will be done before actual induction of labor.
- Trial name
- NCT03113227
- Testing
- Transvaginal ultrasound, Vaginal examination
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Plaque Psoriasis
Non-interventional Study of the Effect of Smoking Status of the Patient on the Success of Etanercept Therapy in Psoriasis
Pilot observational study to describe the relationship between the smoking status of a psoriatic individual and the success of etanercept therapy in psoriasis treatment
- Trial name
- NCT02192164
- Testing
- smoking questionnaire
- Where
- 8 sites in Hungary
- Volunteers
- 126 people
- Sponsor
- Pfizer
Headache
Prednisolone in the Treatment of Withdrawal Headache in Probable Medication Overuse Headache
The purpose of this study is to determine whether prednisolone is more effective than placebo in the first six days after initiation of medication withdrawal therapy for a medication overuse headache.
- Trial name
- NCT00135122
- Testing
- prednisolone
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Sorlandet Hospital HF
Peripheral Artery Disease
SUCCESS (SelUtion, Safety, effiCaCy, hEalth economicS and promS) PTA Study
Open label, real-world, prospective, multi-center, single arm, post-market surveillance study of the SELUTION SLR™ (Sustained Limus Release) drug eluting balloon (DEB).
- Trial name
- SUCCESS PTA (NCT04776434)
- Testing
- SELUTION SLR™ (Sustained Limus Release) drug eluting balloon (DEB)
- Where
- 27 sites in Argentina, Germany and 6 more
- Volunteers
- 723 people
- Sponsor
- M.A. Med Alliance S.A.
Lymphoma, Myeloma
Evaluation of the Success of Prophylactic Enteral Nutrition in Therapeutic Intensification With Autograft of Autologous Hematopoietic Cells in Hematology
When the digestive tract is functional, learned societies recommend the use of a nutritional support by enteral feeding. Indeed, it has many advantages (maintenance of gut trophicity, reduction of the risk of infection by…
- Trial name
- GAGNE (NCT04703985)
- Testing
- Enteral Nutrition
- Where
- 2 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Bordeaux
Surgery, Anesthesia, Endotracheal
The Videolaryngoscopy in Small Infants
Complications related to infant (≤ 1 year) airway management are under-appreciated because of few rigorous and targeted studies.
- Trial name
- VISI (NCT03396432)
- Testing
- Video Laryngoscopy for ET placement, Direct Laryngoscopy for ET Placement
- Where
- 5 sites in United States, Australia
- Volunteers
- 566 people
- Sponsor
- Children's Hospital of Philadelphia
Delirium
Description of Therapy Options and Successes in the Long-term Course of Delirium in the Recovery Room - CESARO II
This project is a multicenter pilot project to evaluate the therapeutic success in the long term up to 3 months after a delirium in a recovery room.
- Trial name
- NCT04920734
- Where
- Germany
- Volunteers
- 5 people
- Sponsor
- Charite University, Berlin, Germany
Urolithiasis, Nephrolithiasis
Does Treatment With Alfuzosin Increase Success Rates of (SWL) Shock Wave Lithotripsy
In latest literature more evidence is available about the positive effect of alpha blocker on stone expulsion from the ureter. Patients benefit from less pain and shortening time to stone expulsion.
- Conditions
- Urolithiasis, Nephrolithiasis, Ureterolithiasis
- Trial name
- NCT00409227
- Testing
- Alpha blocker-alfuzosin
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Carpal Tunnel Syndrome, Perfusion Index
Is Perfusion Index an Indicator of Block Success in Ultrasound-guided Infraclavicular Brachial Plexus Block
The infraclavicular nerve block, which is frequently preferred in upper extremity surgeries, provides additional advantages such as reduction in opioid consumption by providing analgesic effect in the postoperative period as…
- Trial name
- NCT04921891
- Testing
- Infraclavicular nerve block, Without nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
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