Clinical trials: Suffering
Acute Cholecystitis
A Randomized Controlled Trial on EGBD vs PC for Acute Cholecystitis.
Acute cholecystitis commonly occurs in elderly patients that are high-risk candidates for surgery. Percutaneous cholecystostomy (PC) is frequently employed for gallbladder drainage in these patients.
- Trial name
- DRAC (NCT02212717)
- Testing
- EUS-guided gallbladder drainage (EGBD), Percutaneous cholecystostomy (PC)
- Where
- 4 sites in China, Japan and 1 more
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Obesity, Binge-Eating Disorder
fMRI Study of Emotion Regulation in Patients Suffering From Obesity With or Without Binge Eating Disorder and Seeking Bariatric Surgery
Obesity is a major public health problem and Binge eating disorder (BED) is very frequently observed in patients considered for weight loss surgery and seems to influence their outcome critically.
- Trial name
- OBéMO (NCT05131256)
- Testing
- Neurofunctional characterization of emotional regulation (fMRI)
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Diabetes type1, Diabetes Mellitus, Type 1
Does the Use of Fiasp vs. Asp Lead to the Prolonged TIR in Children With Type 1 Diabetes?
The aim of the study is to assess whether the implementation of faster insulin aspart in children with Type 1 diabetes treated with intensive insulin therapy with the use of an insulin pump and using Real Time Continuous Glucose…
- Trial name
- NCT04772729
- Testing
- Insulin faster aspart (Fiasp, Novo Nordisk)
- Volunteers
- 77 people
- Sponsor
- Medical University of Warsaw
Osteoarthritis, Knee, Pain, Joint
Assessment of the Effect of Spa Treatment on Rheumatological Conditions
1. Primary outcome measure: measuring the effect of spa treatment in patients suffering from lower limb osteoarthritis or any other lower limb rheumatological condition.
- Conditions
- Osteoarthritis, Knee, Pain, Joint, Lower Back Pain, Rheumatic Diseases
- Trial name
- CONTREXEVILLE (NCT03538470)
- Testing
- Spa Treatment
- Where
- 4 sites in France
- Volunteers
- 150 people
- Sponsor
- SAEML Contrexéville
Cardiovascular Events
Secondary Prevention Treatment in Patients Who Have Suffered a Cardiovascular Event
AstraZeneca was interested in knowing how Cardiologists and Physicians treat patients who have suffered a cardiovascular event.
- Trial name
- NCT01395550
- Volunteers
- 88 people
- Sponsor
- AstraZeneca
Acute Myocardial Infarction
Sitagliptin Plus Granulocyte-colony Stimulating Factor in Acute Myocardial Infarction
Trial design: This Phase III, investigator-driven, randomised, placebo-controlled efficacy and safety study will compare the effects of Sitagliptin in combination with granulocyte-colony stimulating factor (Lenograstim, G-CSF) on…
- Trial name
- SITAGRAMI (NCT00650143)
- Testing
- Lenograstim (GRANOCYTE)=GCSF, Sitagliptin (Januvia), Sodium Chloride (NaCl) 0.9 %
- Where
- Germany
- Volunteers
- 174 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Aspiration Pneumonia
Aspiration Pneumonia in Cerebrovascular Stroke Patients Suffering From Bulbar Palsy
One of the most serious complications in the critically ill patient complaining of bulbar palsy is aspiration pneumonia. These patients are scheduled for nasogastric tube feeding trying to avoid recurrent aspiration and…
- Trial name
- TPN (NCT06395740)
- Testing
- Enteral nutrtion, TPN
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Acute Illness
Degree-of-worry and Illness Perception in Patients Suffering From Acute Illness in the Emergency Department
This study explores whether and how DOW, as a PRO marker, can contribute to triage in the Emergency Departments. The study is designed as a mixed-method study consisting of a survey among acutely ill patients and qualitative…
- Trial name
- NCT04226040
- Testing
- DOW and illness perception
- Where
- Denmark
- Volunteers
- 944 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Stroke, Hydrotherapy
Effects of an Aquatic Therapy Program Versus a Land Program in Patients Who Suffered a Stroke
The objective of this study is to investigate the relative effectiveness of CCT on water versus on land in stroke patients. Additionally, the study will to determine if there are differences in the results obtained, between two…
- Trial name
- NCT02999971
- Testing
- circuit class therapy in water, circuit class therapy on land
- Volunteers
- 23 people
- Sponsor
- Universidade da Coruña
Allergic Rhinitis, Allergic Rhinoconjunctivitis
Demonstration of a Decongestant Effect of "Coldamaris Akut" Compared to Saline Nasal Spray.
Allergic rhinitis (AR) in its seasonal and perennial form is a common allergic condition. The majority of allergic rhinitis sufferers report nasal (congestion, sneezing, itching and rhinorrhea) and ocular (redness, watery eyes…
- Trial name
- NCT04532762
- Testing
- nasal spray
- Where
- Austria
- Volunteers
- 42 people
- Sponsor
- Marinomed Biotech AG
Schizophrenia
A Clinical Study That Will Assess the Effect of SEP-363856 or Prior Antipsychotic (PA) Standard of Care on Body-weight Associated Parameters in Subjects With Schizophrenia
A Clinical Study that will look at an investigational medication, SEP-363856 (called "study medication") in patients with schizophrenia, and assess wether it affectsbody-weight associated parameters.
- Trial name
- NCT05542264
- Testing
- SEP-363856, Prior antipsychotic (risperidone, olanzapine, quetiapine or aripiprazole)
- Where
- 4 sites in United States
- Volunteers
- 19 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Gastroesophageal Reflux Disease, Gastro-oesophageal Reflux
Observational Study (This Means That no Drug is Tested) in Patients Suffering of Gastroesophageal Reflux Disease.
The purpose of this observational study (this means that no drug is being tested in this study) is to obtain updated and detailed information about the Gastroesophageal Reflux Disease (GERD) specificities in European patients.
- Conditions
- Gastroesophageal Reflux Disease, Gastro-oesophageal Reflux, Gastro-Esophageal Reflux, Esophageal Reflux
- Trial name
- PROFILE (NCT01601379)
- Volunteers
- 7,964 people
- Sponsor
- Janssen-Cilag International NV
Thrombotic Thrombocytopenic Purpura, Congenital Thrombotic Thrombocytopenic Purpura
Genotype and Phenotype Correlation in Hereditary Thrombotic Thrombocytopenic Purpura (Upshaw-Schulman Syndrome)
Hereditary thrombotic thrombocytopenic purpura (Upshaw-Schulman syndrome) is a rare disorder characterized by thrombocytopenia as a result of platelet consumption, microangiopathic hemolytic anemia, occlusion of the…
- Conditions
- Thrombotic Thrombocytopenic Purpura, Congenital Thrombotic Thrombocytopenic Purpura, Familial Thrombotic Thrombocytopenic Purpura, Thrombotic Thrombocytopenic Purpura, Congenital
- Trial name
- TTP registry (NCT01257269)
- Testing
- Observation
- Where
- 7 sites in United States, Austria and 5 more
- Volunteers
- 450 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Knee Osteoarthritis
Safety of Use of Pandora for Patients Suffering From Gonarthrosis
The knee osteoarthritis is a frequent degenerative condition that mainly affects subjects over 60, population often weakened by numerous comorbidities and concomitant treatments, justifying the development of new therapies.
- Trial name
- PANDORA1 (NCT05414617)
- Testing
- Intra-articular single injection, Intra-articular three injections
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- Labrha
Cancer, Adolescent Behavior
Impact of Sick Peer Relation on Adaptation to Disease and on Treatment of Cancer-suffering Adolescents & Young Adults
Adolescents and young adults (AYA) with cancer have to deal with a relatively segmented organization of care between pediatric and adult medicine structures in France.
- Conditions
- Cancer, Adolescent Behavior, Young Adult
- Trial name
- PAIRS-AJA (NCT03964116)
- Testing
- Questionnaires set all 3 months
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Institut Curie
Parkinson Disease
Executive Control Analysis in Patients Suffering From Parkinson Disease and Treated by Deep Brain Stimulation
Different results have recently led to question the classical notion according to which the motor and cognitive deficits in Parkinson's disease are tied to a thalamo-cortical inhibition due to the degeneration of the dopaminergic…
- Trial name
- NCT00922909
- Testing
- Simon task
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Microbiota
Stability of the Microbiome in IBD and IBS
In this study the investigators aim to investigate the changes of the intestinal microbiome in three different cohorts (IBD, IBS, healthy) after applying the uniform disruptive factor of osmotic diarrhea induced by macrogol.
- Trial name
- NCT03395548
- Testing
- Macrogol
- Where
- Austria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Major Depressive Disorder
Safety of Liposom With Citalopram in Elderly Patients With Major Depressive Disorder
The purpose of this study is to determine if Liposom Forte will enhance the response to antidepressant therapy with citalopram in elderly patients suffering from Major Depressive Disorder (MDD).
- Trial name
- NCT04975724
- Testing
- Liposom Forte, Citalopram
- Where
- 12 sites in Italy
- Volunteers
- 150 people
- Sponsor
- Fidia Farmaceutici s.p.a.
Endometriosis
The Immune Base of Endometriosis
Endometriosis is a chronic disabling inflammatory disease which effects 15-20% of women in their reproductive life. In patients suffering from endometriosis retrograded menstrual cells induce an inflammatory…
- Trial name
- NCT00370123
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Overactive Bladder, Urinary Incontinence
Propiverine in Children Suffering From Non-Neurogenic Overactive Bladder and Urinary Incontinence
The study was conducted between 2004 and 2006 to prove efficacy and tolerability of the antimuscarinic propiverine compared to placebo in children suffering from non-neurogenic overactive bladder and urinary incontinence.
- Conditions
- Overactive Bladder, Urinary Incontinence, Children
- Trial name
- NCT00603343
- Testing
- Mictonetten 5 mg, coated tablet
- Volunteers
- 303 people
- Sponsor
- APOGEPHA Arzneimittel GmbH
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