Clinical trials: Suffering
Lateral Ankle Instability
Retrospective Study of Suture Tape for Soft Tissue Reconstruction in Patients Suffering From Lateral Ankle Instability
This study is intended to be a retrospective chart review of patients with chronic ankle instability who have undergone a lateral ligament reconstructive procedure for ATFL repair (isolated or non-isolated) with suture tape…
- Trial name
- NCT06829667
- Testing
- Arthrex InternalBrace
- Where
- 4 sites in United States
- Volunteers
- 103 people
- Sponsor
- Stryker Trauma and Extremities
Schizophrenia
Escitalopram in Schizophrenia in OCD- Open Label Study
SSRI's has been demonstrated to be partially effective in schizophrenia and OCD. We therefore suggest that Escitalopram up to 20 mg /d in those patients could be effective in reducing obsessive compulsive symptomatology
- Trial name
- NCT00456937
- Testing
- Escitalopram
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- BeerYaakov Mental Health Center
Age-Related Macular Degeneration
Effect of Micronutrient Supplementation on the Intestinal Microbiota in Patients With Age-related Macular Degeneration - The Gut-Retina-axis Study
Age-related macular degeneration (AMD) is a leading cause of visual impairment in the elderly, characterized by multifactorial etiology.
- Trial name
- NCT06391411
- Testing
- a micronutrient mix containing lutein (10 mg), zeaxanthin (2 mg), saffron (20 mg), vitamin C (80 mg), vitamin E (12 mg) and zinc (10mg), anti-VEGF treatment
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Knee Osteoarthritis
Efficacy and Safety Study in Patients Suffering From Knee Osteoarthritis
The primary objective of this study is to compare a combination of hyaluronic acid and chondroitin sulfate (V0220) to Hyalgan® on pain relief in patients with symptomatic knee osteoarthritis (OA) over 24 weeks when administered…
- Trial name
- VESTA (NCT01469507)
- Testing
- Chondroitin sulfate and sodium hyaluronate, Hyaluronan
- Sponsor
- Pierre Fabre Medicament
Axial Spondylarthritis (r-axSpA)
A Study to Assess Disease Activity in Adult Participants With Axial Spondyloarthritis Who Receive Upadacitinib in a Real-world Setting
Axial spondyloarthritis (axSpA) is an immune-mediated inflammatory disease primarily affecting the axial skeleton. The most frequent axSpA symptom is chronic, often inflammatory back pain that might be difficult to distinguish…
- Trial name
- UpSPINE (NCT05094128)
- Testing
- Upadacitinib
- Where
- 72 sites in Germany
- Volunteers
- 338 people
- Sponsor
- AbbVie
Reflux
Do Patients Who Have Had Surgery for Achalasia Suffer From Reflux
Patients who have had laparoscopic surgery for the treatment of achalasia will be asked to have pH studies done in order to determine is these patients suffer from reflux after surgery.
- Trial name
- NCT00519441
- Testing
- pH study
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Kenneth Luberice
Atopic Dermatitis
Broncho-Vaxom (OM 85 BV) in Children Suffering From Atopic Dermatitis
The objective of this pilot double-blind study was to evaluate the efficacy and the safety of Broncho-Vaxom 1 capsule (3.5 mg) per day for 9 months compared to placebo on the evolution of the disease in children suffering from…
- Trial name
- NCT03047954
- Testing
- Broncho-Vaxom
- Volunteers
- 179 people
- Sponsor
- Vifor Pharma
Osteoarthritis, Knee
Evaluation of Mangoselect® in Improvement of Exercise/Activity-induced Knee Joint Discomfort in Subjects Suffering From Osteoarthritis Grade I or II
The aim of the present investigation is to evaluate the efficacy of Mangoselect®, a mangosteen extract, and of a formulation containing Mangoselect®, in subjects suffering from activity/exercise-induced knee joint…
- Trial name
- NCT04765189
- Testing
- Verum A, Verum B, Verum C
- Where
- Spain
- Volunteers
- 95 people
- Sponsor
- Fytexia
Upper Respiratory Infections
Warming Sensation Intensity and Acceptability of the Flavour, Local Tolerability of Paracetamol 500 mg + Pseudoephedrine 30 mg Syrup in Patients Suffering a URTI
This is an open label, in-use study to assess the warming sensation, acceptability and local tolerability of paracetamol 500 mg + pseudoephedrine 30 mg syrup, given as a single dose in subjects suffering from symptoms of an upper…
- Trial name
- NCT01586962
- Testing
- IFF flavor 316 282, Paracetamol, Pseudoephedrine
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- Novartis
Substance Related Disorder, Personality Disorders
The Impact of the Use of the MAURISSE Application in People Suffering From an Addiction.
Substance Use Disorders (SUD) are associated with cognitive schemas that lead to care attrition and mistrust towards care. Considering this, establishing a strong, trustful relationship between the patient and the healthcare team…
- Trial name
- ALMA (NCT05964296)
- Testing
- The MAURISSE application use, Usual care
- Where
- France
- Volunteers
- 41 people
- Sponsor
- University Hospital, Toulouse
Primary Central Nervous System Lymphoma
Maintenance Treatment Versus Observation in Elderly Patients With PCNS Lymphoma
Hypothesis Our hypothesis is that maintenance chemotherapy will prolong complete remission obtained after a standard induction chemotherapy with an acceptable toxicity in the elderly.
- Trial name
- BLOCAGE-01 (NCT02313389)
- Testing
- Rituximab, Methotrexate, Temozolomide
- Where
- France
- Volunteers
- 428 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obstructive Sleep Apnea, Excessive Daytime Sleepiness
BF2.649 in Patients With OSA, Still Complaining of EDS and Refusing to be Treated by CPAP.
Multicenter randomized double blind study versus placebo during 12 weeks with at first, an escalating dose period followed by stable dose period at the selected dose.
- Trial name
- HAROSA2 (NCT01072968)
- Testing
- BF2.649
- Where
- France
- Volunteers
- 268 people
- Sponsor
- Bioprojet
Hemophilia A
Study to Learn More About the Physical Activity Level of Patients Suffering From Hemophilia A Treated With Damoctocog Alfa Pegol (LIFE ACTIVE Study)
In this study researcher want to learn more about the change of physical activity of hemophilia A patients treated with damoctocog alfa pegol.
- Trial name
- LIFE-ACTIVE (NCT04091386)
- Testing
- Damoctocog alfa pegol (Jivi, BAY94-9027)
- Where
- 8 sites in United States, Belgium and 5 more
- Volunteers
- 10 people
- Sponsor
- Bayer
End-of-Life, Physical Suffering
Virtual Reality Therapy to Improve Physical and Psychological Symptoms and Quality of Life for End-of-life Patients on a Palliative Care Unit
People with advanced and life-threatening illnesses experience challenges across multiple domains of function including physical, psychological, social, and spiritual.
- Conditions
- End-of-Life, Physical Suffering, Psychological Distress
- Trial name
- NCT04966260
- Testing
- Standardized Virtual Reality, Control, Personalized Virtual Reality
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- Baycrest
COPD
A COPD Data Registry for Participants With Frequent Exacerbations
This registry will collect data on COPD, including the course of disease, treatment patterns, and potential new therapies. The registry will also track the experience of participants and caregivers in clinical practice.
- Trial name
- AIREIC (NCT07059273)
- Sponsor
- Hoffmann-La Roche
Pudendal Neuralgia, Canal Syndrome
Therapeutic Effects Analysis of Pudendal Nerve Infiltrations After 3 Months, in Patients Suffering of Pudendal Neuralgia
Pudendal neuralgia is a recent identified pathology, extremely invalidating, related to chronic pelvic entrapment. Nowadays, pudendal neuralgia can be treated with: neuropathic pains treatment specific kinesitherapy Alcock's…
- Trial name
- INFILTHERA (NCT00851513)
- Testing
- Lidocaine, Depmedrol, physiological serum
- Where
- 9 sites in France
- Volunteers
- 202 people
- Sponsor
- Nantes University Hospital
Walking Performance
Evaluating Walking Kinetic of Children Who Suffer Central Nervous System (CNS) Damage
The goal of the present study is to look at the effect of changing walking parameters on the dynamic walking characteristics among children post severe traumatic brain injury, and typically developed controls.
- Trial name
- NCT01158027
- Testing
- gait evaluation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Anemia
An Observational Study of NeoRecormon (Epoetin Beta) in Anemic Patients With Non-myeloid Malignancy
This observational, prospective, multicenter study will evaluate the treatment response rate and the safety of NeoRecormon (epoetin beta) in anemic patients with non-myeloid malignancy.
- Trial name
- NCT01716559
- Where
- 6 sites in Hungary
- Volunteers
- 160 people
- Sponsor
- Hoffmann-La Roche
Multiple System Atrophy
Quality of Life of Caregivers and Patients Suffering From Multiple System Atrophy
Multiple system atrophy (MSA) is a rare and fatal neurodegenerative disorder that cause as other neurodegenerative diseases profound declines in functioning and thus, require caregiving for assistance with daily living.
- Trial name
- QUA2-AMS (NCT04965922)
- Testing
- Multimodal intervention
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Fibromyalgia, Emotional Trauma
Hyperbaric Oxygen Therapy Compared to Pharmaceutical in Fibromyalgia With Emotional Trauma
The investigators have previously studied the efficacy of hyperbaric oxygen therapy (HBOT) as a treatment for Fibromyalgia syndrome (FMS) in a prospective, active control, crossover clinical trial.
- Trial name
- NCT04316702
- Testing
- Hyperbaric oxygen therapy (HBOT) treatment, Cymbalta / Lyrica - Drug treatment
- Where
- Israel
- Volunteers
- 48 people
- Sponsor
- Assaf-Harofeh Medical Center
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