Clinical trials: Suffering
Bipolar Disorder With Manic or Mixed Episodes
Safety and Efficacy of MEM 1003 Versus Placebo for the Treatment of Patients With Bipolar I Disorder
The purpose of this study is to establish the potential of MEM 1003 as a safe and effective treatment for patients with an acute manic or mixed episode of bipolar disorder.
- Trial name
- NCT00374920
- Testing
- MEM 1003
- Where
- 21 sites in United States
- Volunteers
- 60 people
- Sponsor
- Memory Pharmaceuticals
Alcohol Dependence, Alcohol Abuse
Community Reinforcement and Family Training (CRAFT) for Treatment-resistant Individuals With Alcohol Use Disorders
The present study examines the efficacy of the Community Reinforcement and Family Training (CRAFT) for Concerned Significant Others (CSOs) of individuals with alcohol use disorders (AUDs) using a randomized waiting list (WL)…
- Trial name
- CRAFT (NCT02112396)
- Testing
- Community Reinforcement and Family Training
- Where
- Germany
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Luebeck
Low Back Pain
Efficacy Safety of a Combination Thiocolchicoside+Ketoprofen Compared to Thiocolchicoside Twice a Day for 7 Days in Patients Suffering From Acute Non Specific Low Back Pain
Primary Objective : To demonstrate the superiority of the oral fixed - combination of a muscle relaxant, thiocolchicoside (TCC) to a non steroidal anti-inflammatory drug, ketoprofen, over oral TCC, on average pain within the last…
- Trial name
- TIOKET (NCT00679146)
- Testing
- Thiocolchicoside+Ketoprofen, Thiocolchicoside
- Where
- 6 sites in Brazil, Colombia and 4 more
- Volunteers
- 334 people
- Sponsor
- Sanofi
Psychological Distress
Indication-based Identification and Psychosocial Treatment of Orthopedic Cancer Patients
Aim of this study is to develop and establish an indication-based algorithm for identifying particular stress patterns of patients with initial diagnosis of a sarcoma or a metastatic bone disease.
- Trial name
- NCT01631175
- Testing
- psychosocial treatment
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Technical University of Munich
Pulmonary Embolism
PUlmonary REhabilitation in Patients Suffering From Post-PE Syndrome
This study is a multicenter, parallel, randomized waitlist-controlled trial that primarily focuses on the short-term benefit of outpatient pulmonary rehabilitation (PR) on patients after acute pulmonary embolism.
- Trial name
- PURE-PE (NCT04615130)
- Testing
- Rehabilitation
- Where
- Austria
- Volunteers
- 48 people
- Sponsor
- Medical University of Vienna
Sprain
Efficacy Study of a Sensory Feedback Knee Orthosis in Patients Suffering From Unoperated Severe Knee Sprain
Ortheses are commonly used for the repair of damage to the musculoskeletal system. However, immobility, by itself, causes serious side effects that require long and costly rehabilitation.
- Trial name
- ORTHOSENS (NCT01508728)
- Testing
- ORTHOSENS orthosis
- Where
- 3 sites in France
- Volunteers
- 104 people
- Sponsor
- Thuasne
Mandibular Fractures
Patients 60 Years and Older Suffering From Mandibular Fractures Registry
Approximately 200 of patients of 60 years or older who present a mandibular fracture will be enrolled in this registry. All patients will be treated and followed up according to the local standard (routine) of care at around 2…
- Trial name
- NCT03849898
- Testing
- Surgery, Non-Surgical fracture treatment
- Where
- 24 sites in United States, Finland and 13 more
- Volunteers
- 25 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Hypertension
Evaluation of a Health Literacy Intervention on Patients Suffering From Hypertension in Primary Care
Hypertension affects 30% of the French population, but only 25% of hypertensive patients meet therapeutic targets, largely due to a limited adherence to lifestyle and medication guidelines (34%).
- Trial name
- IHTALi (NCT07015463)
- Testing
- Multi-component intervention in health literacy
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Dermatitis, Atopic
Protopic Ointment in Children Atopic Eczema
Children with atopic eczema and a poor response to topical corticosteroid applied either Protopic or Fluticasone ointment twice a day for 3 weeks. They could continue during 3 more weeks once a day if needed.
- Trial name
- NCT00689832
- Testing
- Tacrolimus 0.03%, Fluticasone 0.005%
- Where
- France
- Volunteers
- 487 people
- Sponsor
- Astellas Pharma Inc
Spinal Cord Injury
Robotic-assisted Locomotor Training on Mobility and Cardiopulmonary Function in Patients Suffering From Spinal Cord Injury
Evidences showed that patients suffering from spinal cord injury (SCI) have poor mobility and higher chance to develop cardiopulmonary diseases, which leads to poor quality of life and shorter life expectancy.
- Trial name
- NCT01989806
- Testing
- Robotic-assisted body weight supported treadmill training (Lokomat V6, Hocoma AG, Switzerland), Passive lower limbs mobilization training (Motomed Vivo 2, RECK, Germany)
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Kowloon Hospital, Hong Kong
Head and Neck Cancer, Claustrophobia
Comparing Radiotherapy Immobilization Systems for Anxious HNC Patients
Background: Radiotherapy is a mainstay of treatment for ENT cancers, and its indication is frequent. Patients are positioned and immobilized using a thermoplastic mask, which is attached to the treatment table for the duration of…
- Conditions
- Head and Neck Cancer, Claustrophobia, Anxiety
- Trial name
- CRISP (NCT06257121)
- Testing
- OSMS position management
- Volunteers
- 15 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Neoplasm Metastasis
Essential Oils on Anxiety of Patients Suffering From Cancer
This study evaluates the impact of essential oils massage on anxiety of patients who are suffering from cancer at a metastasis stage. Half of patients will be massaged first by essential oils and then by oil only.
- Trial name
- RHECAP (NCT02835352)
- Testing
- Essential oils massages, Oil massages
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Center Eugene Marquis
Prader-Willi Syndrome
Characterization of Serum Proteome in Subjects With Prader Willi Syndrome (PROTEOMARKER)
The lack of serum markers that can be used to identify the levels of steatosis in obese subjects, or that can indicate a rapid progression of the metabolic disease, in which it is very often difficult to perform analyzes with…
- Trial name
- PROTEOMARKER (NCT05761184)
- Testing
- Serum collection for proteomic analysis
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Istituto Auxologico Italiano
Epilepsies, Partial
A Long Term Follow up Administration Study of L059 (Levetiracetam) in Epilepsy Patients With Partial Onset Seizures
This study is planned to evaluate the safety and efficacy of L059 (levetiracetam) in long-term administration in patients who completed N01020 [NCT00160165] or N01221 [NCT00280696].
- Trial name
- NCT00367432
- Testing
- Levetiracetam
- Where
- 53 sites in Japan
- Volunteers
- 398 people
- Sponsor
- UCB Japan Co. Ltd.
Chronic Cornel Edema
Study to Evaluate the Safety of the EndoArt™ for Treatment of Subjects Suffering From Corneal Edema
Prospective, feasibility study to evaluate the safety of the EndoArt® for treatment of 30 subjects suffering from corneal edema. Followed up for 12 months.
- Trial name
- NCT03069521
- Testing
- EndoArt® Artificial Endothelial Layer
- Where
- 8 sites in Germany, Israel and 2 more
- Volunteers
- 22 people
- Sponsor
- Eye-yon Medical
Cognitive Impairment
Evaluation of the Effect of Cooled Haemodialysis on Cognitive Function in Patients Suffering With End-stage KD
The Investigators aim to perform a feasibility study that will inform the development of a definitive, fully powered, randomised, controlled clinical trial in the future.
- Trial name
- E-CHECKED (NCT03645733)
- Testing
- Lower Temperature Group
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- Heart of England NHS Trust
Ankylosing Spondylitis
Benefit of Adapted Physical Activity for Patients Suffering From Ankylosing Spondylitis
The current management of Spondylarthritis Ankylosant (SA), according to the recommendations of the HAS (High Authority of Health), must be a multidisciplinary global approach coordinated by the rheumatologist combining a…
- Trial name
- SPIKE (NCT04089774)
- Testing
- Adapted Physical Activity (APA)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Acute Pain
Paracetamol UNIFLASH for Buccal Use Phase III Trial in Acute Pain Due to a Tooth Extraction
This study aims to evaluate the analgesic efficacy of single dose of a new paracetamol formulation (paracetamol UNIFLASH) for buccal use in comparison to two different doses of an oral paracetamol form controlled versus placebo.
- Trial name
- NCT04640376
- Testing
- Paracetamol Uniflash 125mg, Panadol 500 MG Oral Tablet X1, Panadol 500 MG Oral Tablet X2
- Where
- 20 sites in France, Italy and 2 more
- Volunteers
- 407 people
- Sponsor
- Unither Pharmaceuticals, France
Overweight or Obesity, Chronic Low-back Pain
Lifestyle Intervention in Overweight/Obese Chronic Low Back Pain (CLBP) Patients: an International Multi-center RCT
Chronic low back pain (CLBP) is the most expensive cause of workrelated disability: it causes the highest number of years lived with disability.
- Trial name
- BO2WL (NCT05811624)
- Testing
- Physiotherapy intervention, including behavioral weight reduction program combined with pain neuroscience education and cognition-targeted exercise therapy., Physiotherapy intervention, including pain neuroscience education and cognition-targeted exercise therapy alone.
- Where
- 2 sites in Belgium, Switzerland
- Volunteers
- 252 people
- Sponsor
- Vrije Universiteit Brussel
COVID-19, ARDS
Losartan and Spironolactone Treatment for ICU Patients With COVID-19 Suffering From ARDS
Coronavirus disease (COVID-19) is a current pandemic infection caused by an RNA virus called Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2).
- Trial name
- COVIDANCE (NCT04643691)
- Testing
- Losartan 50 mg and Spironolactone 25 mg pillules oral use
- Where
- France
- Volunteers
- 78 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
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