Clinical trials: Suffering
Stress, Psychological Cumulative, Chronic Disease
Randomised Clinical Trial to Determine the Effect of Vagus Nerve Neurodynamics on the Neurovegetative Nerve System in People With Chronic Stress.
This unicentric, controlled clinical trial aims to evaluate the effects of vagus nerve neurodynamics and 6 bpm guided breathing, combined with manual therapy, on heart rate variability (HRV) in patients suffering from chronic…
- Conditions
- Stress, Psychological Cumulative, Chronic Disease, Heart Rate Variability, Vagal Nerve Stimulation
- Trial name
- VNN-HRV-CCS (NCT06499662)
- Testing
- Vagus Nerve Neurodynamics, Guided Breathing, Manual Therapy
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- Marta de la Plaza
Knee Osteoarthritis
Assessment of Safety and Efficacy of ARTHRUM 2.5% for Treatment of Painful Osteoarthritis of the Knee
ARTHRUM 2.5% MONO-INJECTION as symptomatic treatment by joint injection extends the conservative therapeutic arsenal in Knee osteoarthritis.
- Trial name
- ART-ONE75 (NCT06228274)
- Testing
- ARTHRUM 2.5%
- Volunteers
- 218 people
- Sponsor
- LCA Pharmaceutical
Functional Dyspepsia
Itopride in Functional Dyspepsia:a Dose Finding Study
This study aims to determine the efficacy and optimal dose of the prokinetic itopride for the treatment of patients with functional dyspepsia.
- Trial name
- NCT00272103
- Testing
- Itopride (drug)
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Royal Adelaide Hospital
Seasonal Allergic Rhinitis
Effect of Intranasal Corticosteroids on Systemic Allergen Specific IgE
Evaluation of the effect of fluticasone propionate vs placebo applied as nasal spray on the increase of allergen-specific serum IgE levels following nasal exposure to recombinant allergens.
- Trial name
- NCT00755066
- Testing
- Fluticasone propionate
- Where
- Austria
- Volunteers
- 48 people
- Sponsor
- Medical University of Vienna
Constipation Chronic Idiopathic
Vibrant Capsule vs. Placebo for Patient Suffering From Constipation
The objectives are to assess the efficacy and safety of Vibrant capsule administered twice a week
- Trial name
- Capsule (NCT05036369)
- Testing
- Vibrant capsule
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Vibrant Ltd.
Bipolar Disorder With Manic or Mixed Episodes
Safety and Efficacy of MEM 1003 Versus Placebo for the Treatment of Patients With Bipolar I Disorder
The purpose of this study is to establish the potential of MEM 1003 as a safe and effective treatment for patients with an acute manic or mixed episode of bipolar disorder.
- Trial name
- NCT00374920
- Testing
- MEM 1003
- Where
- 21 sites in United States
- Volunteers
- 60 people
- Sponsor
- Memory Pharmaceuticals
Autistic Spectrum Disorder, Somatic Disorders
Somatic Diseases in Autistic Children
For many reasons, medical monitoring in autistic patients is very difficult. This study is designed to determine the prevalence of comorbid diseases (neurological, cardiac, digestive, dental diseases…) in patients suffering from…
- Trial name
- SDA (NCT05077020)
- Where
- France
- Volunteers
- 27 people
- Sponsor
- University Hospital, Montpellier
BMI Greater Than 30
Establishment of a Database of Patients Suffering From Obesity With a Medical Treatment
Obesity is a public health problem, given its prevalence (15% in France in 2012, Obépi survey) but also by the complications that it generates. We were firstly, intersted in bone mineral density during obesity.
- Trial name
- Elodie Cohort (NCT03755323)
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Montpellier
Asthma, Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Implementation of a Joint Pulmonologist and ENT Consultation in the Care Pathway of Patients Suffering From Asthma and Chronic Rhinosinusitis With Nasal Polyposis: Effectiveness Compared With Consultations by Specialty (CON-PO Study).
Asthma affects the lower respiratory tract (bronchi), whereas chronic rhinosinusitis with nasal polyposis (CRSwNP) involves the upper airways.
- Trial name
- CON-PO (NCT07134686)
- Testing
- Joint consultation, Mucus sampling, Nasal brushing
- Where
- France
- Volunteers
- 195 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Chronic Kidney Disease
Study on the Safety of the Drug Runcaciguat and How Well it Works When Given at the Highest Dose as Tolerated by Individual Patient Whose Kidneys Are Not Working Properly and Suffering at the Same Time From High Blood Sugar and/or High Blood Pressure and a Disease of the Heart and the Blood Vessels.
Researchers in this study want to learn more about the safety of the drug runcaciguat and how well it works when given at the highest dose as tolerated by the individual patient whose kidneys are not working properly and…
- Trial name
- CONCORD (NCT04507061)
- Testing
- runcaciguat
- Where
- 71 sites in Austria, Belgium and 11 more
- Volunteers
- 243 people
- Sponsor
- Bayer
Atopic Dermatitis
Evaluation of the Efficacy of TOPIALYSE Baume Protect+ on Atopic Dermatis
The purpose of this study is to evaluate the efficacy and tolerability of a SVR care product. As we know, atopic dermatitis is a vicious circle that must be broken, but certain aggravating factors are added to this circle.
- Trial name
- TOPIAbis (NCT06108570)
- Testing
- Cosmetic Product TOPIALYSE Baume Protect+
- Where
- 3 sites in Belgium
- Volunteers
- 60 people
- Sponsor
- SVR Group
Multiple Myeloma
Development of a Standardized Reference Guide for Tuning Adherence to Dispense During a Initial Pharmaceutical Consulting (CP ) to the Patient With Multiple Myeloma Oral Chemotherapy Primocure
The hypothesis is that the implementation of an initial Pharmaceutical Consultation (PC) program based on the provision of standardized information to patients treated for multiple myeloma as a first course of chemotherapy, could…
- Trial name
- NCT04045561
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Adult Growth Hormone Deficiency
Safety and Efficacy Study of Recombinant Human Growth Hormone in Adult Growth Hormone Deficiency Patients
The purpose of this study is to assess the safety, tolerability and Pharmacokinetic/ Pharmacodynamic (PK/PD) profile of three doses of HM10560A on an every week (EW) regime and one dose on every other week (EOW) regime…
- Trial name
- HM10560A (NCT01822340)
- Testing
- HM10560A, Genotropin
- Where
- Hungary
- Volunteers
- 72 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Migraine
Auditory Functions in Patients With Migraine
Migraine is a neurological disease associated with an altered cortical excitability level . The prevalence of migraine is10.5% of adults in Assiut governorate, and is more frequent in women and in individuals with higher…
- Trial name
- NCT04575623
- Testing
- Duration Pattern test (DPT) /Dichotic Digits Test (DDT) /Auditory fusion test-revised (ART-R)/, Dual band pure tone audiometer (Orbiter 992). -Impedance audiometer (AT 235h). -Sound treated booth (industrial acoustic company IAC model 1602-A-t) -Panasonic stereo CD player SA-AK 240.
- Volunteers
- 120 people
- Sponsor
- Assiut University
Ischemic Stroke, Acute
Randomization to Extend Stroke Intravenous ThromboLysis In Evolving Non-Large Vessel Occlusion With TNK (RESILIENT
A phase III, randomized, multi-center clinical trial that will examine whether treatment with intravenous TNK is superior to placebo in patients who suffer a non-large vessel occlusion ischemic stroke within 4.5-12 hours from…
- Trial name
- EXTEND-IV (NCT05199662)
- Testing
- Intravenous tenecteplase
- Where
- 15 sites in Brazil
- Volunteers
- 466 people
- Sponsor
- Hospital Moinhos de Vento
Pain, Urinary Tract Infections
Evaluate the Safety and Efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg vs. Placebo
This study will evaluate the safety and efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg as a short term analgesic treatment for the primary symptoms of pain or burning when passing urine associated with…
- Trial name
- NCT01064024
- Testing
- Phenazopyridine Hydrochloride
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- Amneal Pharmaceuticals, LLC
Systemic Sclerosis
Trial on Outpatients With Systemic Sclerosis Treated With Well-Being Therapy or With a Control Therapy
Systemic sclerosis (SSc) is a rare and potentially life-threatening autoimmune disorder with a significant impact on health and quality of life.
- Trial name
- NCT04212247
- Testing
- Well-Being Therapy, Control condition
- Where
- 2 sites in Italy
- Volunteers
- 60 people
- Sponsor
- University of Florence
Rheumatoid Arthritis
Intra-articular Injection of Etanercept in Patient Suffering From Rheumatoid Arthritis : a Double-blind Randomized Study
Intra-articular injection of etanercept in patient suffering from rheumatoid arthritis: a double-blind randomized study for evaluation of efficacy and safety of etanercept versus intra-articular steroid injection in acute…
- Trial name
- NCT00522184
- Testing
- intra-articular injection of etanercept, intra-articular injection of steroid
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Exercise, Health Behavior
Implementation of a 12-week Adapted Physical Activity (APA) Program in People Suffering From Chronic Insomnia.
One third of men and women are not satisfied with their sleep. A non-drug countermeasure to improve sleep in insomniacs could be adapted physical activity (APA).
- Conditions
- Exercise, Health Behavior, Sleep
- Trial name
- NCT05294133
- Testing
- physical activity
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Universite du Littoral Cote d'Opale
Major Depressive Disorder
LSD Therapy for Persons Suffering From Major Depression
Background: Major Depressive Disorder is one of the most prevalent mental illnesses, leading to substantial personal distress and economical consequences. Pharmacological Treatment is limited and relapse is frequent.
- Trial name
- LAD (NCT03866252)
- Testing
- LSD
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Basel, Switzerland
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