Clinical trials: Suffering
Facial Pain, Temporomandibular Joint Disorder
Diagnosis and Evaluation of Patients Needing Third Molar (Wisdom Tooth) Extraction and Patients With Chronic Facial Pain
This study provides a mechanism for evaluating patients for possible participation in NIDCR clinical research studies. NIDCR studies involve three major areas-pain, neurosensory mechanisms, and pain-relieving drugs-all of which…
- Trial name
- NCT00001600
- Where
- United States
- Volunteers
- 4,000 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Physical Suffering, Post Procedural Discharge
Determining the Severity of Physical Symptoms Displayed and Their Level of Perceived Readiness for Discharge After Birth
H1a: There is a difference between the severity of physical symptoms displayed by puerperal women who received routine and personalized care during the early postpartum period.
- Trial name
- NCT04656756
- Testing
- Personalized Care
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Aysegul Durmaz
Bladder Cancer
Comparison Capsule Sparing Cystectomy and Radical Cystoprostatectomy in Men With Bladder Cancer
Bladder cancer is a common malignant tumor of the urinary system, radical resection plus urinary diversion is the first choice of treatment for muscle invasive bladder cancer.
- Trial name
- NCT05067101
- Testing
- Capsule Sparing Cystectomy (CSC), Conventional Radical Cystoprostatectomy (CRC)
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Zhujiang Hospital
Bronchopulmonary Dysplasia
Use of Mesenchymal Stem Cells in Pre-term Patients With Bronchopulmonary Dysplasia.
Bronchopulmonary dysplasia (BPD) is a disease that affects preterm newborn patients, preventing their lungs from developing properly.
- Trial name
- NCT06270199
- Testing
- Control, Allogenic fetal mesenchymal stem cells from umbilical cord - three infusions, Allogenic fetal mesenchymal stem cells from umbilical cord - six infusions
- Where
- 7 sites in Spain
- Volunteers
- 75 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Immune System Diseases
Impact of HLNatural Immune Supplement on Colds
According to the Centers of Disease Control and Prevention (CDC) adults will have an average of 2-3 colds per year. Most colds will last approximately 7-10 days.
- Trial name
- NCT04103099
- Testing
- HLNatural Immune
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Hawthorne Effect Inc.
Narcolepsy, Hypersomnia
Method of Assessment of Driving Ability in Patients Suffering From Wakefulness Pathologies
The project will improve scientific knowledge regarding a recent law applying potentially to every french driver. It will give for the first time an indication on the impact of alerting treatments on driving risks.
- Trial name
- AUTOSOP (NCT00916253)
- Testing
- Modafinil
- Where
- 2 sites in France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Polytrauma Patients
Evaluation of Patients Suffering From Polytrauma Admitted to the ICU
The primary objective of this study is to assess the number of polytrauma patients admitted to the Intensive Care Unit. In addition, we aim to describe their clinical characteristics, therapeutic management, and clinical outcomes.
- Trial name
- Polytrauma ICU (NCT07482267)
- Where
- Belgium
- Volunteers
- 417 people
- Sponsor
- Jessa Hospital
Head and Neck Tumors
Analysis of HPV and Biomarkers Present in the Biological Fluids of Patients Suffering From Head and Neck Cancer as a Non-invasive Strategy for Detecting Recurrence
Multicenter, non-interventional, retrospective/prospective biological study on patients affected by head and neck tumors, for which the collection and use of tissue samples, blood and saliva for the detection of HPV-DNA/RNA and…
- Trial name
- NCT06224166
- Testing
- Collection and use of tissue samples, blood and saliva
- Where
- Italy
- Volunteers
- 283 people
- Sponsor
- Regina Elena Cancer Institute
Non-cancer Pain, Opioid Induced Constipation
Prucalopride Effects on Subjects With Chronic Non-cancer Pain Suffering From Opioid Induced Constipation
The study will evaluate the efficacy, safety and tolerability of prucalopride over 12 weeks of treatment in subjects aged 18 years and older with chronic non-cancer pain, suffering from opioid induced constipation.
- Trial name
- OIC (NCT01117051)
- Testing
- prucalopride
- Where
- Belgium
- Volunteers
- 174 people
- Sponsor
- Shire
Alzheimer Disease, Presbycusis
Clinical Trial on Alzheimer Disease, Presbycusis and Hearing Aids
This is a 12-months' randomized clinical trial that aims at studying the benefit of bilateral hearing aids in hearing impaired patients suffering from a slight to moderate stage Alzheimer disease.
- Trial name
- NCT00488007
- Testing
- Hearing aids used : PHONAK Savia and Valeo
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Hospices Civils de Lyon
Schizophrenia
Escitalopram in Schizophrenia in OCD- Open Label Study
SSRI's has been demonstrated to be partially effective in schizophrenia and OCD. We therefore suggest that Escitalopram up to 20 mg /d in those patients could be effective in reducing obsessive compulsive symptomatology
- Trial name
- NCT00456937
- Testing
- Escitalopram
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- BeerYaakov Mental Health Center
Headache
Evaluation of the Efficacy of Manual Therapy, Therapeutic Exercise and the Two Modalities Combined in Pain Reduction in Patients With Headache
The study aims to evaluate which is the best approach for the non-pharmacological treatment of patients with different types of primary headaches (tension-type headache (TTC), trigeminal autonomic headache (TACs) and migraine) or…
- Trial name
- NCT05990153
- Testing
- Myofascial Release (MR), clinical practice drug treatment, Manual therapy (MT)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Campus Bio-Medico University
Macular Degeneration
Evaluation of Visual Function and Driving Health Using Ocusweep in Patients Suffering From Wet Age-related Macular Degeneration
The aim is to study the use of Ocusweep system especially in driving health evaluation and compare the results produced by Ocusweep system to those of conventional devices.
- Trial name
- NCT02747368
- Testing
- Ocusweep system
- Volunteers
- 600 people
- Sponsor
- Turku University Hospital
Rhinitis, Allergic, Perennial
ATAREAL (Antihistamine Treatment for Allergic Rhinitis in Real Life)
Comparison of clinical efficacy and safety of levocetirizine in PER continuous versus on demand, measured by evolution of individual symptom scores during 6 months.
- Trial name
- NCT00160680
- Testing
- Levocetirizine
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- UCB S.A. - Pharma Sector
Major Depressive Disorder
Identification of Physiological Data by a Wearable Monitor in Subjects Suffering From Major Depression Disorders
To evaluate, over a period of six months, the links between physiological data collected such as electrodermal activity (or Galvanic Skin Response), motor activity measured by accelerometer, heartbeat measured by…
- Trial name
- MYND104 (NCT05547035)
- Testing
- Patient follow-up of depression
- Where
- 11 sites in France
- Volunteers
- 200 people
- Sponsor
- Digital For Mental Health
Ankylosing Spondylitis
Benefit of Adapted Physical Activity for Patients Suffering From Ankylosing Spondylitis
The current management of Spondylarthritis Ankylosant (SA), according to the recommendations of the HAS (High Authority of Health), must be a multidisciplinary global approach coordinated by the rheumatologist combining a…
- Trial name
- SPIKE (NCT04089774)
- Testing
- Adapted Physical Activity (APA)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Suicidal Behaviour, Cognitive Functions Confusion
Analysis of Parameters Indicating the Intensity of Suicidal Behavior in Psychiatric Patients
The aim of this study was to analyse the level of cognitive functioning of patients with history of suicidal behaviour suffering from depression and schizophrenia, and to evaluate their oxidative stress parameters and selected…
- Trial name
- NCT05803447
- Testing
- Interview questionnaire, biochemical parameters, cognitive function
- Volunteers
- 120 people
- Sponsor
- Medical University of Bialystok
Stroke, Oculomotor; Disorder
Oculomotor and Cognitive Rehabilitation Using Visual Feedback in Stroke Patients
Investigators will test the effectiveness of oculomotor cognitive training using eye tracker-based device during rehabilitation course in patients with a degree of disability no more than 3 points on a scale Rankin.
- Conditions
- Stroke, Oculomotor; Disorder, Attention Disturbances
- Trial name
- NCT05309148
- Testing
- Training on eye tracker based device, Training with a neuropsychologist, Training on eye tracker based device and with a neuropsychologist
- Where
- Russia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Breast Neoplasms, Neoplasm Metastasis
Lux-Breast 3; Afatinib Alone or in Combination With Vinorelbine in Patients With Human Epidermal Growth Factor Receptor 2 (HER2) Positive Breast Cancer Suffering From Brain Metastases
The aim of this study is to investigate the efficacy and safety of afatinib alone or in combination with vinorelbine, as treatment in patients with HER2-overexpressing metastatic breast cancer, who have progressive brain lesions…
- Trial name
- NCT01441596
- Testing
- Vinorelbine, Investigator's choice of treatment, afatinib
- Where
- 40 sites in United States, Canada and 6 more
- Volunteers
- 121 people
- Sponsor
- Boehringer Ingelheim
Stroke
Validation of a French Quality of Life Questionnaire Adapted to Persons Who Have Suffered a Stroke
The aim of this work is to develop and validate a scale adapted to French cultural characteristics. It will be based on the SS-QoL scale and be simple and quick to use in everyday practice. It is not simply a translation.
- Trial name
- QUALI STROKE (NCT02855970)
- Testing
- completion of a quality of life questionnaire
- Where
- France
- Volunteers
- 61 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
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