Clinical trials: Suicidal Behavior
Suicidal Ideation
The Effect of Ketamine on the Length of Hospital Stay of Patients Hospitalized With Suicidal Ideation.
This study will evaluate the effect of ketamine on the treatment of patients hospitalized with suicidal thoughts. Half of the patients will receive one dose of ketamine in the vein. The other half will receive a placebo.
- Trial name
- NCT02997722
- Testing
- Ketamine, Normal Saline
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Allen Richert
Depressive Disorder
M3VAS Validation in Polish Population
Low mood and anhedonia represent the fundamental symptoms of major depressive disorder (MDD). Nevertheless, there is currently no standardized visual analogue scale available to assess the extent of both symptoms concurrently.
- Trial name
- NCT06412562
- Testing
- The Maudsley 3-item Visual Analogue Scale (M3VAS)
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Gdansk
Suicidality
Intensive Outpatient Treatment for Suicidal Veterans
This investigation is a feasibility study conducted in a VA outpatient treatment setting. The study is designed to test the feasibility of implementing a novel way of working with suicidal patients, the Collaborative Assessment…
- Trial name
- CAMS (NCT01334372)
- Testing
- CAMS
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- VA Eastern Colorado Health Care System
Major Depressive Disorders
Loneliness and Occurrence of Suicide Attempts and Suicidal Ideas
Suicide is a major health problem that causes annually a million death worldwide. Loneliness is known to be associated with suicidal ideation in minors and to be related with suicidal risk in elderly people.
- Trial name
- SOLSTIS (NCT02829671)
- Testing
- Clinical and biological assessment
- Volunteers
- 600 people
- Sponsor
- University Hospital, Montpellier
Military Transition, Community Reintegration
Transition Health and Resilience Through Valued Experiences (THRiVE) Pilot for Newly Separated Veterans
The objective of this study is to develop and pilot a program designed to improve mental health outcomes and reduce suicide risk during the transition from military to civilian life.
- Conditions
- Military Transition, Community Reintegration, Mental Health, Suicidal Ideation
- Trial name
- NCT06778278
- Testing
- Transition Health and Resilience through Valued Experiences (THRiVE) Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- RTI International
Post-Traumatic Stress Disorders
KIDNET vs Meditation/Relaxation - a Dissemination Randomized Controlled Trial for the Treatment of Traumatized Children After War in Sri Lanka
The purpose of this study is to assess the efficacy of KIDNET versus a Meditation/Relaxation protocol in treating traumatized children when applied by locally trained teacher counsellors as well as the effectiveness and adequacy…
- Trial name
- NCT00564317
- Testing
- KIDNET, Meditation/Relaxation
- Where
- Sri Lanka
- Volunteers
- 48 people
- Sponsor
- University of Konstanz
Non Suicidal Self Injury, Suicidal Ideation
aiTBS for NSSI and Suicide in Adolescent Depression
Repetitive transcranial magnetic stimulation (rTMS) has been successfully used to help patients with treatment resistant depression.
- Conditions
- Non Suicidal Self Injury, Suicidal Ideation, Suicide and Self-harm
- Trial name
- NCT06210100
- Testing
- Active iTBS
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Central South University
Mood Disorders, Suicide, Attempted
Youth Suicide Risk Factors, Reduction of Suicide Risk Factor in Youth People
The YOU-SURF project is at the forefront of youth suicide prevention, with the goal of integrating multimodal clinical and neurobiological data to comprehensively identify risk factors and the most effective intervention…
- Conditions
- Mood Disorders, Suicide, Attempted, Suicidal Ideation, Suicide Prevention
- Trial name
- YOU-SURF (NCT07188506)
- Testing
- Clinical and blood parameters, Illumina Infinium Global Screening Array 4.0 (GSA 4.0), dTMS treatment
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Autism Spectrum Disorder, Suicidal Ideation
Adapted Visual Safety Plan for Autistic Youth (VSP-AY) to Address Self-harm, Suicidal Ideation, and Suicide Behaviors
This pilot randomized controlled trial will recruit 90 autistic adolescents aged 13-18 years with recent suicidal thoughts or behaviors from Geha Mental Health Center in Israel.
- Conditions
- Autism Spectrum Disorder, Suicidal Ideation, Suicidal Behavior, Self-Injurious Behavior
- Trial name
- VSP-AY (NCT07333014)
- Testing
- Adapted Visual Safety Plan for Autistic Youth (VSP-AY) to Address Self-harm, Suicidal Ideation, and Suicide Behaviors
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- College of Management Academic Studies
Suicidal Ideation
Clinical and Imaging Trial of Uridine for Veterans With Suicidal Ideation
This is a randomized, double-blind, placebo-controlled study of the investigational drug uridine as a treatment for suicidal ideation in veterans.
- Trial name
- NCT03265964
- Testing
- Uridine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- VA Office of Research and Development
Suicidal Ideation, Suicide, Attempted
Suicide Prevention in Prepubertal Children
Suicidal ideation and behaviors are estimated to be as high as 4-16% and 1.5% (respectively) in the general 6-12-year-old population.
- Trial name
- NCT04171089
- Testing
- Child- Safety Plan Intervention
- Where
- United States
- Sponsor
- New York State Psychiatric Institute
Suicide, Attempted, Suicidal Ideation
Biomarkers as Predictors of Suicidal Risk in Adolescents
Suicide is one of the most devastating events in society at all levels. The primary goal of this study is to predict suicide in adolescents at risk.
- Conditions
- Suicide, Attempted, Suicidal Ideation, Suicidal Intention, Suicide
- Trial name
- NCT03014518
- Testing
- Clinical assessments and blood samples; follow-up for 12 mos, Clinical assessments and blood samples; no 12mo follow-up
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Suicide
Coping Long Term With Attempted Suicide - Adolescents
This study is to develop an adjunctive intervention for acutely suicidal adolescents who have been admitted to a psychiatric inpatient unit.
- Trial name
- CLASP-A (NCT01748760)
- Testing
- CLASP-A intervention, Treatment as Usual
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brown University
Suicidal Ideation
Unique Effects of Perimenstrual Estradiol or Progesterone Supplementation on Perimenstrual Suicidality
This within-person, crossover, 3-condition, placebo-controlled study compares the impact of three perimenstrual conditions on severity of suicidal symptoms in females with past-month suicidality but minimal risk of imminent…
- Trial name
- CLEAR-2 (NCT03498313)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Illinois at Chicago
Depression, Suicidal Ideation
Low-Dose Intravenous Ketamine for Adolescents With Depression and Suicidal Ideation in the Emergency Department
The goal of this study is to test whether a single low-dose of IV ketamine given in the emergency department to adolescents with treatment-resistant depression and suicidal ideation can reduce depression symptoms and suicidal…
- Trial name
- NCT05217706
- Testing
- Ketamine, normal Saline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rady Children's Hospital, San Diego
Binge Alcohol Consumption, Suicidal Ideation
Preliminary Trial of an Avatar Guided Digital Intervention for Emerging Adults
The goal of this clinical trial is to learn whether a novel digital avatar (virtual coach) support program can help emerging adults ages 18-29 who present to the emergency department with suicidal thoughts and alcohol misuse…
- Trial name
- EA-Avatar (NCT07418047)
- Testing
- EA-Avatar, Suicide safety planning app
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Massachusetts, Worcester
Mental Health Disorder, Suicide Attempt
Efficacy of the I-CARE Digital Health Intervention
When presenting to an ED with suicide, self-harm or other mental health crises, youth may also experience "boarding", which is defined by the Joint Commission as "the practice of holding patients in the ED or another temporary…
- Conditions
- Mental Health Disorder, Suicide Attempt, Suicidal Ideation, Emergency Psychiatric
- Trial name
- NCT07150832
- Testing
- Improving Care, Accelerating Recovery & Education (ICARE)
- Where
- 4 sites in United States
- Volunteers
- 173 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Suicidal Ideation Active, Depression Disorders
Personalized TACS to Reduce Rumination in Patients with Active Suicidal Ideation
The goal of this clinical trial is to determine whether modulating default mode network (DMN) alpha connectivity using transcranial alternating current stimulation (tACS) can reduce rumination and, in turn, mitigate feelings of…
- Trial name
- Alpha-MOD (NCT06832124)
- Testing
- alpha-tACS
- Volunteers
- 50 people
- Sponsor
- Sebastian Olbrich
Major Depressive Disorder, Major Depressive Episode
SAINT for MDD in an Inpatient Setting Follow-on
Randomized, multi-site, sham-controlled, double-blinded study
- Conditions
- Major Depressive Disorder, Major Depressive Episode, Suicidal Ideation
- Trial name
- NCT06462820
- Testing
- Active SAINT Stimulation
- Where
- 4 sites in United States
- Volunteers
- 2 people
- Sponsor
- Magnus Medical
Posttraumatic Stress Disorder, Depression
A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Pilot
The goal of this pilot study is to develop and implement a larger scale, multi-site stepped collaborative care trial that targets injured patients with presentations of posttraumatic stress disorder (PTSD) and related…
- Conditions
- Posttraumatic Stress Disorder, Depression, Alcohol-Related Disorders, Suicidal Ideation
- Trial name
- TSOS6 (NCT02335125)
- Testing
- Motivational Interviewing, Cognitive Behavioral Therapy Elements, Psychotropic Drugs
- Volunteers
- 40 people
- Sponsor
- University of Washington