Clinical trials: Suicidal Behaviour, open to volunteers
Suicide, Suicide and Self-harm
Feasibility, Acceptability, and Preliminary Efficacy of a Novel Personalized Mobile Intervention for Suicide - Open Trial (2)
The primary aim of this grant is to conduct pilot testing on a novel personalized mobile intervention for suicide - Mobile Application to Prevent Suicide (MAPS) - and to establish feasibility, acceptability, safety, and primary…
- Conditions
- Suicide, Suicide and Self-harm, Suicide, Attempted, Suicidal Ideation
- Trial name
- NCT05180344
- Testing
- Mobile Application to Prevent Suicide (MAPS)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Butler Hospital
Bipolar II Disorder, Depression, Bipolar
Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality
The purpose of the study is to assess the safety and acceptability of up to two sequential administrations of 25 mg psilocybin with additional therapeutic support in decreasing suicidality in patients with Bipolar Disorder (BD…
- Conditions
- Bipolar II Disorder, Depression, Bipolar, Suicidality
- Trial name
- NCT06706232
- Testing
- Psilocybin, Therapeutic Support
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The University of Texas Health Science Center, Houston
Suicidal Ideation, Suicide, Attempted
Randomized Clinical Trial of Re-Evaluating Suicidal Thoughts in Veterans
Suicide prevention is a top priority for VA as all continue to seek new and inventive ways to reduce suicide rates among Veterans.
- Trial name
- REST-V (NCT05884476)
- Testing
- Treatment-as-usual, Re-Evaluating Suicidal Thoughts
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- VA Office of Research and Development
Depressive Disorder, Suicidal Ideas
Evaluation of the Efficacy and Safety of Subcutaneous Ketamine in the Treatment of Depressive Episode With Suicidal Ideation and/or Behavior in Adolescents
Evaluate the efficacy and safety of subcutaneous ketamine added to usual treatment in the management of depressive episodes with suicidal ideation or behavior in adolescent patients, compared to usual treatment added to placebo…
- Trial name
- NCT06957704
- Testing
- ketamine, Midazolam
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Psychological Distress, Suicidal Ideation
Flourish in Schools Pilot Study
This study will test Flourish, a digital suicide prevention intervention for cyberbullied youth, within schools. Specifically, the study aims to: 1.
- Trial name
- NCT07506525
- Testing
- Flourish
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Candice Biernesser
Suicidal Ideation
Suicide Treatment Alternatives for Teens
Quasi-Randomized trial to compare inpatient care versus outpatient crisis intervention clinic. This study plans to enroll up to 1,000 participants across 4 sites in a 5 years period.
- Trial name
- START (NCT04089254)
- Testing
- Inpatient Psychiatry, Outpatient Crisis Intervention Clinic
- Where
- 4 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Suicide Prevention, Suicide Attempt
Smartphone App Enhanced Facilitation Among Veterans in a Mental Health Inpatient Setting (Project HOPE)
This study will test whether a novel intervention, Virtual Hope Box Enhanced Facilitation (VHB-EF), reduces suicide risk in Veterans after discharge from inpatient psychiatric hospitalization.
- Conditions
- Suicide Prevention, Suicide Attempt, Suicide Ideation
- Trial name
- Project HOPE (NCT06378541)
- Testing
- Virtual Hope Box Enhanced Facilitation, Enhanced Usual Care
- Where
- United States
- Volunteers
- 928 people
- Sponsor
- VA Office of Research and Development
Depression, Anxiety
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Efficacy of a Multi-level School Intervention for LGBTQ Youth
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior
- Trial name
- NCT05541406
- Testing
- Proud & Empowered, Control Group
- Where
- 23 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Older Adults (50-90 Years), Mental Health
Project HOPEFUL: A PN-RCT With Implementation Science
This PN-RCT replicates and evaluates an 8-week warm calling treatment (i.e. caring contacts) delivered to older adults receiving home and community-based services (HCBS; classified as "homebound") in 20-30 minute call "dosages"…
- Conditions
- Older Adults (50-90 Years), Mental Health, Depression and Suicide Ideation, Social Functioning
- Trial name
- NCT07475039
- Testing
- Standardized and manualized warm calls from providers trained in the BE training, Standardized and manualized warm calls from providers trained in the BE training + ASIST training
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Florida
Suicide
Text-based Support for Parents of Adolescents Following an Emergency Department Visits
The goal of this study is to determine the effectiveness of an adaptive text-based intervention for parents of adolescents seeking emergency department services for suicide risk concerns.
- Trial name
- TESP (NCT06660199)
- Testing
- Text-based intervention
- Where
- 2 sites in United States
- Volunteers
- 420 people
- Sponsor
- University of Michigan
Suicidal Ideation, Circadian Rhythm Disorders
Mind After Midnight
This study examines whether wakefulness during the biological night (2:00-4:00 AM) is associated with increased negative mood, impaired decision-making, and suicidal thoughts.
- Conditions
- Suicidal Ideation, Circadian Rhythm Disorders, Sleep Deprivation, Sleep Wake Disorders
- Trial name
- MaM (NCT07438912)
- Testing
- Sleep Pressure Manipulation
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Arizona
Suicide Prevention, User Experience
Evaluation of the Quality of Chat Conversations With the Suicide Helpline Zelfmoordlijn 1813
Suicide remains a serious public health issue in Flanders. Every day, nearly three people die by suicide, and many more attempt it or struggle with suicidal thoughts.
- Conditions
- Suicide Prevention, User Experience, Suicide, Suicidal Ideation
- Trial name
- CHATQ-1813 (NCT07176156)
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 373 people
- Sponsor
- University Ghent
Stigma, Social, Help-Seeking Behavior
Personalized Normative Feedback for Stigma and Help-seeking
People tend to care about what others think and often change our behaviors accordingly. But what if people do not have an accurate understanding of what others really think? Stigma is pervasive, especially in the Black and Asian…
- Trial name
- NCT07683819
- Testing
- Personalized Normative Feedback (PNF), Attention control
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Han Oh
Suicide Risk, Suicide Attempt
Study to Refine the Effectiveness of New Generation Therapies for Suicide
The purpose of this research study is to improve the effectiveness of a well-established therapy for suicidal thoughts and behaviors called Brief Cognitive Behavioral Therapy (BCBT) for Suicide Prevention.
- Conditions
- Suicide Risk, Suicide Attempt, Treatment Response
- Trial name
- STRENGTHENS (NCT07818889)
- Testing
- Brief Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Ohio State University
Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder
Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)
The goal of this clinical trial is to learn if intravenous (IV) ketamine with Dialectical Behavioural Therapy (DBT) reduces suicidal ideation in individuals with suicidality who have been diagnosed with Borderline Personality…
- Conditions
- Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder, Treatment-resistant Bipolar Depression, Major Depressive Disorder (MDD)
- Trial name
- KET-DBT (NCT07569198)
- Testing
- Ketamine Hydrochloride, Midazolam Hydrochloride, Dialectical Behavioral Therapy (DBT)
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Joshua Rosenblat
Mental Health Disorder, Suicide Attempt
Efficacy of the I-CARE Digital Health Intervention
When presenting to an ED with suicide, self-harm or other mental health crises, youth may also experience "boarding", which is defined by the Joint Commission as "the practice of holding patients in the ED or another temporary…
- Conditions
- Mental Health Disorder, Suicide Attempt, Suicidal Ideation, Emergency Psychiatric
- Trial name
- NCT07150832
- Testing
- Improving Care, Accelerating Recovery & Education (ICARE)
- Where
- 4 sites in United States
- Volunteers
- 173 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Suicide Prevention, Suicidal Ideation
Online Suicide Prevention and Intervention Training for Secondary School Counselors
The aim of this study is to develop and evaluate the effectiveness of the Online Suicide Prevention and Intervention Training Program (Çevrimiçi İntihar Önleme ve Müdahale Eğitim Programı - ÇİÖMEP) for school counselors working…
- Conditions
- Suicide Prevention, Suicidal Ideation, School Counseling
- Trial name
- NCT07432438
- Testing
- Online Suicide Prevention and Intervention Training Program (ÇİÖMEP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Persons With High Suicide Ideation or Attempts
Cognition, Metacognition, and Stigma in Patients With Suicidal Ideation
Deficits of executive function, meta cognition and stigma is known in suicidal ideation; however, their relationship is unknown.
- Trial name
- NCT06652815
- Testing
- Suicide ideation or suicide attempt
- Volunteers
- 212 people
- Sponsor
- University of Pittsburgh
Nonsuicidal Self Injury, Pain Empathy
Altered Neural Pain Empathic Reactivity in NSSI Adolescents
Nonsuicidal self-injury (NSSI) is defined as direct, deliberate bodily harm without suicidal intention. In recent years, growing evidence suggests that NSSI has become a worldwide public health issue.
- Trial name
- NCT05968313
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China