Clinical trials: Suicidal Behaviour
Autism Spectrum Disorder, Depression
Group Depression Treatment for Autistic Youth
Higher rates of depression are reported by autistic adolescents as compared to their non-autistic peers, which is problematic given adverse outcomes (e.g., negative self-esteem, lower academic performance) that are associated…
- Conditions
- Autism Spectrum Disorder, Depression, Suicidal Ideation, Self Esteem
- Trial name
- NCT05430022
- Testing
- Autism-adapted Group Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Vanderbilt University Medical Center
Suicidal Ideation, Treatment Refusal
Assessment of Emotion Regulation Strategies Used When Suicidal
Crisis Response Planning is an efficacious, one-session intervention that increases positive affect, decreases negative affect and psychiatric hospitalizations, and reduces suicide attempts by 76% among Servicemembers.
- Conditions
- Suicidal Ideation, Treatment Refusal, Emotion Regulation
- Trial name
- NCT05722197
- Testing
- Crisis Response Planning and Lethal Means Safety Counseling
- Where
- United States
- Volunteers
- 334 people
- Sponsor
- Ohio State University
Suicidal Ideation
Adjunctive Duration-doubled tDCS for the Treatment of Depressive Patients With Suicidal Ideation
In this double-blinded, randomized, sham-controlled trial, the investigators aim to determine the acute effectiveness of duration-doubled tDCS on suicidal ideation in patients with MDD.
- Trial name
- NCT05555927
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Shanghai Mental Health Center
Suicidal Ideation
The Elders' Resilience Curriculum
The overall goal of this research is to better understand if and how the Elders' Resilience Curriculum (ERC), a culturally grounded, school-based upstream suicide prevention program taught by White Mountain Apache Tribe (WMAT)…
- Trial name
- NCT06045273
- Testing
- Elders' Resilience Curriculum
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Suicide
A Psycho-educational Intervention for People With Suicidal in Prisons
This study has been designed as a multicentric, randomized, two parallel-group, controlled trial. The study population will be male and female inmates of nine prisons of Catalonia (Spain).
- Trial name
- N'VIU (NCT05195554)
- Testing
- Psycho-educational intervention
- Where
- Spain
- Volunteers
- 178 people
- Sponsor
- Consorci Hospitalari de Vic
Suicidal Ideation
RCT Investigating EMDR for Suicidal Ideation
Suicide is a major public health issue, and is the 9th leading cause of death overall. Suicidal thinking and behaviours have been linked to painful childhood experiences, stressors, and psychological trauma.
- Trial name
- NCT04181047
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR), Usual care
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Alberta
Major Depressive Disorder, Suicide
Pain, Reward, Attention and Neurocircuitry: Biomarkers of Suicidality
The ultimate aim of this study is to identify a biomarker of suicide risk in MDD by measuring the "hedonic spectrum" (pain and reward responsivity), attention and its associated brain structures using brain scans (fMRI and DTI)…
- Conditions
- Major Depressive Disorder, Suicide, Suicidal Ideation
- Trial name
- NCT02811198
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Suicidal Ideation
Treatment Seeking Study
The study team conducted a randomized controlled clinical trial of 809 military service members who were at increased risk for suicide but not currently in behavioral health treatment.
- Trial name
- NCT05077514
- Testing
- Experimental: Cognitive Behavior Therapy, Active comparator: National Crisis Line
- Where
- 2 sites in United States
- Volunteers
- 809 people
- Sponsor
- Medical University of South Carolina
Suicidal Ideation, Major Depressive Disorder
Adaptation of Dialectical Behavior Therapy Skills-Groups for Individuals With Suicidal Ideation and Depression
Harley and colleagues demonstrated that adding Dialectical Behavior Therapy (DBT) skills-groups and therapist consultation to treatment as usual successfully reduced symptoms of depression.
- Trial name
- NCT01441258
- Testing
- Dialectical Behavior Therapy Skills (DBT-S) Groups, Wait List-Treatment as Usual, No intervention-treatment as usual
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Maurizio Fava, MD
Self Harm, First Episode Psychosis
Psychosocial Intervention for Suicidal Ideation in Individuals With FEP: A Feasibility Trial
To check the feasibility and acceptability of Culturally adapted Cognitive Behavioral Therapy for Psychosis (CaCBTp) and Culturally Adapted Manual Assisted Brief Psychological Intervention for Self-harm (CMAP), which we have…
- Trial name
- CMAP-FEP (NCT05728138)
- Testing
- CMAP Plus CBT
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Pakistan Institute of Living and Learning
Suicidal Ideation, Depression
Trial of the Rapid Antisuicidal Effects of Intranasal Ketamine in Comorbid Depression and Alcohol Abuse
This project aims to evaluate the potential rapid and sustained antisuicidal and antidepressant effects of a single intranasal dose of ketamine in inpatients during a mood episode in Major Depressive Disorder (MDD) or Bipolar…
- Conditions
- Suicidal Ideation, Depression, Alcohol Abuse
- Trial name
- NCT03539887
- Testing
- Intranasal ketamine
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- The University of Texas Health Science Center, Houston
Suicidal Ideation, Suicide Attempt
The Epidemiology of Suicide Attempts and Suicidal Thoughts in Flanders
The objective of this study is to collect data in Flanders on the incidence of suicide attempts and suicidal ideation across various healthcare settings.
- Conditions
- Suicidal Ideation, Suicide Attempt, Multicenter Study, Epidemiological Study
- Trial name
- BC-03869 (NCT07021404)
- Testing
- Semi-structured interview (Guideline for Suicide care and Evaluation =LOES)
- Where
- 33 sites in Belgium
- Volunteers
- 50,000 people
- Sponsor
- University Hospital, Ghent
Suicidal Ideation
SAFETY-A for Promoting Equity in Suicide Prevention Outcomes in Schools
This study will adapt Safe Alternatives For Teens and Youth - Acute (SAFETY-A) for implementation in low-resourced school districts to reduce racial/ethnic disparities in mental health service use (MHS) following identification…
- Trial name
- NCT05834660
- Testing
- Safe Alternatives for Teens and Youth-Acute for Schools (SAFETY-A for Schools)
- Where
- United States
- Volunteers
- 347 people
- Sponsor
- University of California, Los Angeles
Non-suicidal Self-injury (NSSI), Adolescent
Neurobiological Markers of Non-suicidal Self-injury and Treatment Mechanisms of Adolescent Self-injury Intervention Skills Training
The goal of this clinical trial is to evaluate the effectiveness and safety of Adolescent Self-Injury Intervention Skills Training (ASIST), a treatment program developed by the research team, compared with treatment as usual…
- Trial name
- ASIST (NCT07910110)
- Testing
- Adolescent Self-Injury Intervention Skills Training (ASIST), Treatment as Usual (TAU)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University
Suicidality
A Study to Assess the Validation and Mapping of the Suicide Ideation and Behavior Assessment
The main purpose of this cross-sectional study is to generate data to support the psychometric properties of the Suicide Ideation and Behavior Assessment Tool (SIBAT) and validate its use in participants at imminent risk of…
- Trial name
- NCT03085108
- Testing
- No Intervention
- Where
- 4 sites in United States
- Volunteers
- 130 people
- Sponsor
- Janssen Scientific Affairs, LLC
Suicidal Ideation and Behavior, Mood Disorders
Videoconference-Based Brief Cognitive Behavioral Therapy for Patients With Mood Disorders at High Risk for Suicide
This study aims to investigate inflammatory biomarkers associated with suicide risk and to evaluate the efficacy of videoconference-based brief cognitive-behavioral therapy (V-BCBT) in patients with mood disorders at high risk…
- Conditions
- Suicidal Ideation and Behavior, Mood Disorders, Suicide Attempt, Cognitive Behavior Therapy
- Trial name
- V-BCBT-BIO (NCT07857291)
- Testing
- Videoconference-Based Brief Cognitive Behavioral Therapy, Treatment as Usual (TAU)
- Where
- South Korea
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Hyung Keun Park
Insomnia, Depression
E-aid Sleep-focused TrEatment for Prevention of Major Depression (STEP-MD)
In the past, there were studies on relationship between insomnia and depression, and those studies found that depression can be the result of untreated insomnia.
- Conditions
- Insomnia, Depression, Self Harm
- Trial name
- NCT03309527
- Testing
- e-aid Cognitive Behavior Therapy, e-aid Sleep Hygiene Education
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Depression, Suicidal Ideation
Emergency Ketamine Treatment of Suicidal Ideation
The objective of the current program of research will be to test whether intranasal ketamine treatment is more effective than placebo in reducing suicidal ideation in suicidal patients presenting for acute treatment in emergency…
- Conditions
- Depression, Suicidal Ideation, Suicidal Impulses
- Trial name
- NCT02183272
- Testing
- Intranasal Ketamine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Cincinnati
Depression
Risperidone and Suicidality in Major Depressive Disorder
The purpose of this trial is to investigate the efficacy of risperidone as an adjunct to an antidepressant treatment in the acute management of suicidality during an episode of major depressive disorder.
- Trial name
- NCT00167154
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Self-Harm, Deliberate, Suicidal Behavior
Intensive Dialectical Behavior Therapy for Self-Harm and Suicidal Behavior in Youth: A Pilot Study
The prevalence of self-harm and suicidal behavior among adolescents has increased dramatically over the past two decades-a fourfold rise that represents both a severe personal burden and a substantial public health challenge.
- Conditions
- Self-Harm, Deliberate, Suicidal Behavior, Borderline Personality Disorder (BPD)
- Trial name
- NCT07450105
- Testing
- Intensive Dialectical Behavior Therapy
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Haukeland University Hospital