Clinical trials: Suicidal Behaviour
Suicidal Behavior
Brief Intervention and Contact (BIC) Program
Suicide is a significant public health concern and causes approximately 1.5 % of all deaths in the general population in Canada.
- Trial name
- BIC (NCT03825354)
- Testing
- BIC
- Where
- Canada
- Volunteers
- 61 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Self Harm, Suicidal Ideation
Leverage Noninvasive Transcutaneous Vagus Nerve Stimulation to Reduce Suicidal Behaviors in Vulnerable Adolescents
Suicidal thoughts, suicide attempts, and suicide are increasingly common in adolescence. Current face-to-face prevention approaches are of limited effectiveness, rely on extensive resources, and are at odds with adolescents'…
- Trial name
- NCT05602779
- Testing
- tVNS Program, Phone App Program, tVNS and Phone App Program
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Notre Dame
Suicidal Ideation, Thoughts of Self Harm
Virtual Hope Box - Effectiveness of a Smartphone App for Coping With Suicidal Ideation
A hope box or self soothing kit is a therapeutic tool employed by clinicians with patients expressing suicidal ideation, significant distress, or otherwise at risk of suicidal or non-suicidal self harm.
- Conditions
- Suicidal Ideation, Thoughts of Self Harm, Coping
- Trial name
- VHB-RCT (NCT01982773)
- Testing
- Virtual Hope Box Smartphone App, Enhanced Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 118 people
- Sponsor
- National Center for Telehealth and Technology
Suicidal Ideation
Improving Caregivers' Ability to Manage Life Stress
The COVID-19 pandemic has led to increased caregiving demands for caregivers of Veterans with dementia. Dementia caregivers are particularly at-risk for depression and anxiety, known risk factors for increased suicidality.
- Trial name
- NCT05539352
- Testing
- Problem Solving Therapy (PST) plus EUC
- Where
- United States
- Sponsor
- VA Office of Research and Development
Suicide Prevention
Safety Planning and Cognitive Behavioral Therapy for Adolescent Suicide Prevention in Mozambique
This implementation research project aims to test the effectiveness and implementation outcomes of suicide safety planning along and a transdiagnostic cognitive behavioral intervention for suicide prevention on decreasing…
- Trial name
- NCT06465381
- Testing
- Safety Planning Intervention, Enhanced Usual Care, Transdiagnostic Cognitive Behavioral Therapy for Suicide Prevention
- Where
- 7 sites in Mozambique
- Volunteers
- 2,100 people
- Sponsor
- University of Washington
Depression, Suicidal Ideation
Text 2 Connect- Texting Intervention for Mental Health Treatment Utilization
Text2Connect (T2C) proposes to test a text-based intervention designed to improve engagement with mental health treatment.
- Trial name
- T2C (NCT04560075)
- Testing
- Text2Connect, Psychoeducational Videos (PE) Only
- Where
- 3 sites in United States
- Volunteers
- 52 people
- Sponsor
- University of Pittsburgh
Suicide
CAMS-RAS: for Suicide Prevention
This Phase I feasibility study endeavors to create a prototype of a tool to determine its feasibility with suicidal patients in emergency departments (EDs). This is not a clinical trial.
- Trial name
- CAMS-RAS (NCT03072875)
- Testing
- CAMS-RAS
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Evidence-Based Practice Institute, Seattle, WA
Suicidal Behaviors
Social Web Mining for Suicide Prevention
According to a recent and alarming WHO (World Health Organisation) report (September 4, 2014), one person dies of suicide every 40 seconds in the world.
- Trial name
- Don't Do It (NCT04052477)
- Where
- France
- Volunteers
- 9 people
- Sponsor
- University Hospital, Montpellier
Suicidal Ideation
Pilot Trial of Mobile Technology for Adolescent Suicidality
The primary objective of this study is to assess the efficacy of a digital intervention in reducing suicidal ideation in adolescents.
- Trial name
- NCT06454136
- Testing
- OTX-207, Comparator App + Treatment as Usual (TAU)
- Where
- 3 sites in United States
- Volunteers
- 228 people
- Sponsor
- Oui Therapeutics, Inc.
Suicide, Suicide and Self-harm
Feasibility, Acceptability, and Preliminary Efficacy of a Novel Personalized Mobile Intervention for Suicide - Open Trial
The primary aim of this grant is to conduct pilot testing on a novel personalized mobile intervention for suicide - Mobile Application to Prevent Suicide (MAPS) - and to establish feasibility, acceptability, safety, and primary…
- Conditions
- Suicide, Suicide and Self-harm, Suicide, Attempted, Suicidal Ideation
- Trial name
- NCT05180331
- Testing
- Mobile Application to Prevent Suicide (MAPS)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Butler Hospital
Suicidal Ideation, Suicide, Attempted
The Group Risk Reduction Intervention Therapy (GRRIT) Project
Investigators will evaluate a group format adaptation of Brief Cognitive-Behavioral Therapy for Suicide (i.e., G-BCBT) on suicide ideation (Aim 1), ability to use coping strategies (Aim 2), and overall mental health (exploratory…
- Conditions
- Suicidal Ideation, Suicide, Attempted, Coping Skills, Depression
- Trial name
- ProjectGRRIT (NCT05401838)
- Testing
- Group Brief Cognitive-Behavioral Therapy (G-BCBT), Dialectical Behavior Therapy (DBT) Skills Group
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- University of North Carolina, Charlotte
Depression, Suicide
Concurrent Treatment for Depressed Parents and DepressedAdolescents
This study will develop an integrated treatment for adolescents who are depressed and suicidal and their parents who are depressed and have a history of suicidality.
- Trial name
- NCT00951821
- Testing
- Concurrent treatment, Adolescent treatment only
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Brown University
Suicidal Ideation, Suicide Attempt
A Future-oriented Group Training for Suicidal Patients
The main goal of this study is to evaluate the effectiveness of a Future-oriented Group training aimed at reducing suicidality in adults.
- Trial name
- NCT05158946
- Testing
- Future Oriented Group Training
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- University Ghent
Depressive Disorder, Major Depressive Disorder, Suicidal Ideation
Evaluation of a Multi-Layered Digital Phenotyping, Digital Safety Plan, and Pharmacogenomic Intervention for Suicide Prevention in Adults With Depression
The goal of this clinical trial is to learn if a multi-layered digital and pharmacogenomic intervention works to prevent suicide re-attempts in adults with depression.
- Conditions
- Depressive Disorder, Major Depressive Disorder, Suicidal Ideation, Suicide, Attempted, Suicide Prevention
- Trial name
- SMARTomicS (NCT07885722)
- Testing
- Digital Monitoring (Active/Passive EMA), Ecological Momentary Intervention (EMI) via Digital Safety Plan, Pharmacogenetic-Guided Care and Therapeutic Drug Monitoring
- Where
- Spain
- Volunteers
- 525 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Borderline Personality Disorder, Impulsive Behavior
Effects of tDCS on Impulsiveness Among People Suffering From Borderline Personality Disorder
The study aims to evaluate the impact of transcranial direct current stimulation (tDCS) on impulsiveness of adults suffering from Borderline Personality Disorder.
- Trial name
- TIMBER (NCT03498937)
- Testing
- Active tDCS
- Where
- 3 sites in France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Suicidal Ideation
(Cost)-Effectiveness of ABFT for Suicidal Youth.
Young adults who attempt to kill themselves is a common and serious mental health problem worldwide and certainly in Belgium and the Netherlands. Fatal suicide is the leading cause of death among young adults.
- Trial name
- REPAIR (NCT05965622)
- Testing
- Attachment Based Family Therapy (ABFT) + Treatment As Usual (TAU), Treatment As Usual (TAU)
- Where
- 13 sites in Belgium, Netherlands
- Volunteers
- 138 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Adolescent Behavior, Suicidal Ideation
Navigating Mental Health Treatment for Black Youth
This study looks to conduct a systematic adaptation of Suicidal Teens Accessing Treatment (STAT-ED) for Black youth presenting in the emergency department who have suicide risk.
- Trial name
- NCT05334381
- Testing
- Adapted STAT-ED, Standard Enhanced Treatment As Usual
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Suicide
Text-based Support for Parents of Adolescents Following an Emergency Department Visits
The goal of this study is to determine the effectiveness of an adaptive text-based intervention for parents of adolescents seeking emergency department services for suicide risk concerns.
- Trial name
- TESP (NCT06660199)
- Testing
- Text-based intervention
- Where
- 2 sites in United States
- Volunteers
- 420 people
- Sponsor
- University of Michigan
Suicide
Effectiveness of a Family-Based Intervention for Adolescent Suicide Attempters (The SAFETY Study)
This study will evaluate the effectiveness of an individually tailored suicide prevention treatment program called SAFETY in reducing suicide and suicide attempts in adolescents.
- Trial name
- NCT00692302
- Testing
- SAFETY, Enhanced usual care
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of California, Los Angeles
Depression
Characterization of Suicidal Depression
Antidepressants are widely used to prevent suicidal risk. However, even though the use of antidepressants has been associated with a 40-60% decrease in suicidal risk, they do not seem to be sufficient and appropriate.
- Trial name
- NCT05046587
- Where
- France
- Volunteers
- 898 people
- Sponsor
- University Hospital, Montpellier