Clinical trials: Suicidal Behaviour
Suicide, Suicidal Ideation
Phone Call Follow-up After Crisis Centre Presentation With Suicidal Ideation and Behaviours.
This goal of this research is to examine the efficacy and feasibility of starting a phone call follow-up program for individuals discharged to the community after presenting to the Crisis Response Centre (CRC), a standalone…
- Conditions
- Suicide, Suicidal Ideation, Suicide, Attempted, Suicide Gesture
- Trial name
- NCT03444935
- Testing
- Follow-up phone call
- Where
- Canada
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Winnipeg Regional Health Authority
Major Depressive Disorder, Suicide
Accelerated iTBS for Depression and Suicidality
The overall objective of this current study is to evaluate the feasibility, safety, and tolerability of "high dose" aiTBS in psychiatric inpatient and outpatients with treatment-refractory unipolar, non-psychotic major depressive…
- Trial name
- RAPID (NCT04441008)
- Testing
- Accelerated Intermittent Theta Burst (aiTBS), Electroconvulsive therapy (ECT)
- Volunteers
- 50 people
- Sponsor
- University of Iowa
Suicidal and Self-injurious Behaviour
Collaborative Adolescent Research on Emotions and Suicide
Suicide is the third leading cause of death among adolescents in the US yet there is a paucity of research on effective treatments for this population.
- Trial name
- CARES (NCT01528020)
- Testing
- Dialectical Behavior Therapy, Individual and Group Supportive Therapy
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- University of Washington
Depressive Disorder, Suicidal Ideas
Evaluation of the Efficacy and Safety of Subcutaneous Ketamine in the Treatment of Depressive Episode With Suicidal Ideation and/or Behavior in Adolescents
Evaluate the efficacy and safety of subcutaneous ketamine added to usual treatment in the management of depressive episodes with suicidal ideation or behavior in adolescent patients, compared to usual treatment added to placebo…
- Trial name
- NCT06957704
- Testing
- ketamine, Midazolam
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Psychological Distress, Suicidal Ideation
Flourish in Schools Pilot Study
This study will test Flourish, a digital suicide prevention intervention for cyberbullied youth, within schools. Specifically, the study aims to: 1.
- Trial name
- NCT07506525
- Testing
- Flourish
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Candice Biernesser
Suicidality
Enhanced Dialectical Behavior Therapy for Adolescents
Suicide is a leading cause of death and significant concerns for adolescents and young adults. Dialectical Behavior Therapy for Adolescents (DBT-A) is an evidence-based intervention that effectively reduces life-threatening…
- Trial name
- NCT07256496
- Testing
- Enhanced DBT-A
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Compass Behavioral Health
Depressive Disorder, Bipolar Disorder
Lithium for Suicidal Behavior in Mood Disorders
Observational evidence and findings from clinical trials conducted for other reasons suggest that lithium, a drug used for the treatment of bipolar disorder, and, to a lesser extent, depression, may reduce rates of suicides and…
- Conditions
- Depressive Disorder, Bipolar Disorder, Suicide, Suicide, Attempted
- Trial name
- Li+ (NCT01928446)
- Testing
- Lithium
- Where
- 28 sites in United States
- Volunteers
- 519 people
- Sponsor
- VA Office of Research and Development
Suicidal Ideation, Suicide Attempt
Attempted Suicide Short Intervention Program for Older Adults (ASSIP-OA): An Evaluation of a Psychosocial Intervention for Suicidal Adults Aged 65+
Older adults are sorely underrepresented in suicide prevention research, despite the fact that suicide rates are higher in this age group than in any other age group in Sweden and in many countries worldwide.
- Conditions
- Suicidal Ideation, Suicide Attempt, Suicide
- Trial name
- NCT06831942
- Testing
- ASSIP-OA, Treatment as Usual (TAU)
- Where
- 2 sites in Sweden
- Volunteers
- 132 people
- Sponsor
- Vastra Gotaland Region
Suicide, Suicidal Ideation
Evaluation of a Training for Healthcare Providers in Supporting Men Experiencing Suicidal Ideation
The primary objective of this study is to assess how healthcare providers perceive and evaluate the developed e-learning. The findings will inform potential adjustments to enhance the e-learning as needed.
- Trial name
- NCT06810713
- Testing
- Gatekeeper training (e-learning)
- Where
- Belgium
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University Ghent
Depressive Disorder, Major Depressive Disorder, Suicidal Ideation
Evaluation of a Multi-Layered Digital Phenotyping, Digital Safety Plan, and Pharmacogenomic Intervention for Suicide Prevention in Adults With Depression
The goal of this clinical trial is to learn if a multi-layered digital and pharmacogenomic intervention works to prevent suicide re-attempts in adults with depression.
- Conditions
- Depressive Disorder, Major Depressive Disorder, Suicidal Ideation, Suicide, Attempted, Suicide Prevention
- Trial name
- SMARTomicS (NCT07885722)
- Testing
- Digital Monitoring (Active/Passive EMA), Ecological Momentary Intervention (EMI) via Digital Safety Plan, Pharmacogenetic-Guided Care and Therapeutic Drug Monitoring
- Where
- Spain
- Volunteers
- 525 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Tobacco Dependence, Suicidal
DBT for Smoking Cessation in High Risk Veterans
Individuals prone to suicidality are typically excluded from tobacco cessation interventions even though they are disproportionately likely to smoke, and even though smoking cessation has been linked to improved mood and reduced…
- Trial name
- NCT06687577
- Testing
- DBT-C, Treatment as usual
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Veterans Medical Research Foundation
Suicidal Ideation and Behavior, HIV
HIV Suicide Prevention With AI-DBT
One in four older persons living with HIV/AIDS (PLWHA) report at least one suicide attempt in their lifetime, and the risk for death by suicide is 100 times higher in PLWHA than in the general population.
- Conditions
- Suicidal Ideation and Behavior, HIV, AIDS (Acquired Immune Deficiency Syndrome)
- Trial name
- NCT07339189
- Testing
- AI-DBT
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Rutgers, The State University of New Jersey
Depression
Exploration of the Relationship Between Inflammation and Integrity of the Blood-Brain Barrier in Suicidal Behaviour
Recent studies have revealed an association between history of suicide attempt and inflammatory markers in both the cerebrospinal fluid and the plasma.
- Trial name
- IBIS (NCT04137458)
- Testing
- Biological analysis
- Where
- France
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Suicidal Ideation, Hopelessness
Randomized Controlled Trial of a Single-session Mechanism-focused Intervention for Suicidal Thoughts and Behaviors
Across multiple models of suicide risk, hopelessness and perceptions of social relatedness (i.e., lack of social connection/thwarted belongingness, perceived burdensomeness) have emerged as candidate mechanisms that maintain…
- Conditions
- Suicidal Ideation, Hopelessness, Wish to Live, Wish to Die
- Trial name
- NCT05816317
- Testing
- Single-Session Mechanism-Focused Intervention (SSMFI), Distress Tolerance Skills Review
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Shannon E. Sauer-Zavala
Major Depressive Disorder (MDD), Suicidal Ideation
Accelerated Intermittent Theta Burst Stimulation for Adolescent and Young Adult Depression With Elevated Suicide Risk
The goal of this clinical trial is to learn if a fast-acting brain stimulation treatment called transcranial magnetic stimulation (TMS) can help people with depression and suicidal thoughts.
- Trial name
- NCT07025720
- Testing
- TMS
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, Davis
Depression
Assessing Treatment Emergent Suicidal Ideation in Patients With Major Depression
This study will develop a new methodology to evaluate any treatment-emergent suicidal ideation that might occur when an antidepressant treatment has been started and/or during times when doses are increased in patients with major…
- Trial name
- SAMS (NCT00532103)
- Where
- 15 sites in United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Mental Health (NIMH)
Major Depressive Disorder, Suicidal Behavior
Basal Plasma Lithium Levels and Suicidal Events
Suicidal behavior is a major public health issue and there are currently no specific treatments for it. However, lithium, the reference treatment for bipolar disorder, have been shown to be effective in preventing suicidal risk.
- Conditions
- Major Depressive Disorder, Suicidal Behavior, Bipolar Disorder
- Trial name
- LIPS (NCT05409794)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 158 people
- Sponsor
- University Hospital, Montpellier
Suicidal Ideation
Evaluation of Creative Materials Supporting Healthcare Professionals in Discussing Suicidality in Children and Adolescents
Preliminary research clearly indicates a significant shortage of evidence-based tools and interventions specifically targeting suicidality among children and adolescents.
- Trial name
- NCT07043231
- Testing
- Creative materials
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Ghent
Suicide
Effectiveness of a Family-Based Intervention for Adolescent Suicide Attempters (The SAFETY Study)
This study will evaluate the effectiveness of an individually tailored suicide prevention treatment program called SAFETY in reducing suicide and suicide attempts in adolescents.
- Trial name
- NCT00692302
- Testing
- SAFETY, Enhanced usual care
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of California, Los Angeles
Suicidal Ideation, Depression
Digital Cognitive Behavior Therapy Program for Suicide Prevention
This study evaluates the efficacy of Thrive, a computerized cognitive behavior therapy program, to reduce depression and anxiety symptoms and to reduce suicidal thinking among adults.
- Conditions
- Suicidal Ideation, Depression, Anxiety
- Trial name
- TM2 (NCT03595254)
- Testing
- Thrive
- Where
- United States
- Volunteers
- 725 people, healthy volunteers welcome
- Sponsor
- Montana State University