Clinical trials: Suicidal Ideation and Behavior
Suicide Attempt
Evaluation of the Risk Associated With Impulsivity and Other Neuropsychological Factors on Suicidal Relapse Within Hospital Emergencies
Suicidal behavior (SB) is a major public health problem in France, with over 10,000 suicides (6th in the EU28) and 220,000 suicide attempts (SA) per year. These data seem underestimated by 20%.
- Trial name
- SUI-PREDICT (NCT03026387)
- Testing
- Neuropsychological battery tests
- Where
- France
- Volunteers
- 650 people
- Sponsor
- University Hospital, Montpellier
Major Depressive Disorder, Bipolar Depression
Chronotherapy Randomized Controlled Trial
Chronotherapy is a term that describes therapeutic alterations of sleep wake cycles. Different variations of sleep deprivation, set sleep wake schedules, and types of light therapy have demonstrated efficacy in rapidly treating…
- Conditions
- Major Depressive Disorder, Bipolar Depression, Suicidal Ideation
- Trial name
- NCT02176824
- Testing
- Total Sleep deprivation, Sleep Phase Advance, and Bright Light Therapy, Partial Sleep deprivation, Sleep Phase Delay, and Low amber light., Treatment as usual
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Medical University of South Carolina
Suicide, Attempted, Suicidal Ideation
Developing and Implementing an Adolescent Suicide Prevention Program in a Community Mental Health Setting
This is a three phase study to develop and implement an adolescent suicide prevention program in a community mental health setting.
- Trial name
- NCT03992391
- Testing
- Suicide Prevention Intensive Outpatient Program
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Texas Southwestern Medical Center
Psychiatric Disorder
Evaluation of a Modularized Cognitive Behavioral Group Therapy Programme for Young Adults (CHANGE-Study)
This prospective, non-randomised, pre-post feasibility study evaluates CHANGE, a novel 8-session modularized cognitive behavioral group psychotherapy for young adults (18-25 years) with psychiatric disorders receiving inpatient…
- Trial name
- CHANGE (NCT07772180)
- Testing
- CHANGE - modularized group psychotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Max-Planck-Institute of Psychiatry
Unipolar Depression, Impulsive Behavior
How to Reduce Suicidal Thoughts and Impulsivity in Depression
The study aims at investigating if tDCS applied to left DLPFC or to right OFC to treatment as usual is effective in reducing severe suicidal ideas in major depressive episode.
- Conditions
- Unipolar Depression, Impulsive Behavior, Suicidal Ideation
- Trial name
- DEPIMPULSE (NCT05894980)
- Testing
- active tDCS stimulating left DLPFC, active tDCS stimulating right OFC
- Where
- 4 sites in France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Anxiety Disorder, Mood Disorder
Does Spiritual/Religious Commitment Mediate the Relationship Between Mood Variability and Suicidal Ideation.
The purpose of this study is to determine whether or not spiritual and/or religious commitment affects mood variability and thoughts of suicide.
- Trial name
- NCT00225459
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Saskatchewan
Suicide
Ketamine & Crisis Response Plan for Suicidal Ideation in the ED
The goal of this randomized pilot trial is to assess the feasibility of administering a combination of 100mg intramuscular (IM) ketamine and Crisis Response Plan (a short psychosocial intervention) for patients with acute…
- Trial name
- NCT05696691
- Testing
- Ketamine Hydrochloride, Crisis Response Plan
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Suicidal Ideation and Behaviors, Suicide Attempt
Video Conference-Based Brief Cognitive Behavioral Therapy for Suicidal High-Risk Outpatients With Mood Disorders
This pilot randomized controlled trial aims to evaluate the feasibility, acceptability, and preliminary effectiveness of videoconference-based brief cognitive behavioral therapy (V-BCBT) for adult outpatients with mood disorders…
- Conditions
- Suicidal Ideation and Behaviors, Suicide Attempt, Cognitive Behavioral Therapy
- Trial name
- V-BCBT (NCT07395817)
- Testing
- Videoconference-Based Brief Cognitive Behavioral Therapy (V-BCBT), Treatment as Usual (TAU)
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Hyung Keun Park
Suicidal Ideation
Pilot Trial of Mobile Technology for Adolescent Suicidality
The primary objective of this study is to assess the efficacy of a digital intervention in reducing suicidal ideation in adolescents.
- Trial name
- NCT06454136
- Testing
- OTX-207, Comparator App + Treatment as Usual (TAU)
- Where
- 3 sites in United States
- Volunteers
- 228 people
- Sponsor
- Oui Therapeutics, Inc.
Insomnia, Depression
Adjunctive Brief Behavioral Treatment of Insomnia (BBTI) for Sleep Intervention (SI)
There is a strong association between sleep disturbance and suicidal thoughts and behaviors. Sleep disturbance is also highly comorbid with other common conditions associated with suicide such as depression and posttraumatic…
- Conditions
- Insomnia, Depression, Posttraumatic Stress Disorder, Suicidal Ideation
- Trial name
- NCT02248675
- Testing
- CBT-I, TAU
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder (PTSD), Suicidal Ideation
Augmenting Massed Cognitive Processing Therapy (CPT) to Prevent Suicide Risk Among Patients With PTSD
The purpose of this research is to see if Crisis Response Planning (CRP), a brief strategy designed to help people cope effectively with emotional crises, combined with Cognitive Processing Therapy (CPT), a talk treatment for…
- Conditions
- Posttraumatic Stress Disorder (PTSD), Suicidal Ideation, Suicide Attempt
- Trial name
- mCPT+CRP (NCT07238192)
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- Ohio State University
Depression, Anxiety
Efficacy of a Brief Intervention to Improve Sexual and Gender Minorities' Mental Health: Randomized Controlled Trial.
Experiences of violence, from micro to physical aggressions, have a deleterious impact on mental health. According to the Minority Stress Theory, unfavorable social conditions (such as anticipated and experienced discrimination…
- Conditions
- Depression, Anxiety, Psychological Distress, Social Phobia
- Trial name
- ESCREVA-SE (NCT05349877)
- Testing
- Expressive writing, Self-affirmation
- Where
- Brazil
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Glioblastoma (GBM)
Mental Health and Suicidality in Glioblastoma Patients in Germany
The aim of the study is to use standardized questionnaires to systematically record influencing factors or predictors for suicidal behavior in glioblastoma patients, particularly with regard to existing depression and anxiety…
- Trial name
- SHINE-GLIO (NCT07409584)
- Testing
- Medical history, physical examination, completing questionnaires, data collection
- Where
- 6 sites in Germany
- Volunteers
- 180 people
- Sponsor
- University Hospital, Essen
Suicide
Ketamine for Acute Suicidal Ideation in the Emergency Department: Randomized Controlled Trial
This study will enroll patients presenting to the emergency department with acute suicidal ideation meeting inclusion and exclusion criteria.
- Trial name
- LDK-SI (NCT01892995)
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Suicidal Ideation, Suicidal Behavior
Understanding and Acting to Regulate Suicidal Behavior
Data from Santé Publique France show that since the onset of the health crisis (covid-19), there has been an increase in emergency room visits for mood disorders among children under 15 years of age, with a notable rise in the…
- Conditions
- Suicidal Ideation, Suicidal Behavior, Self-harm Behavior, Adolescents
- Trial name
- CARES (NCT06689657)
- Testing
- Cognitive behavioral group therapy for adolescents and non violent resistance group for parents, Adolescent group therapy (CARES) and parent group therapy (RNV)
- Volunteers
- 108 people
- Sponsor
- University Hospital, Montpellier
Non Suicidal Self Injury, Suicidal Ideation
aiTBS for NSSI and Suicide in Adolescent Depression
Repetitive transcranial magnetic stimulation (rTMS) has been successfully used to help patients with treatment resistant depression.
- Conditions
- Non Suicidal Self Injury, Suicidal Ideation, Suicide and Self-harm
- Trial name
- NCT06210100
- Testing
- Active iTBS
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Central South University
Depressive Disorder, Generalized Anxiety Disorder
Qualitative Study of Student Financial Insecurity and Psychiatry
Since the COVID-19 pandemic, mental health disorders have increased significantly, particularly among young people. In France, the proportion of young people aged 18 to 25 suffering from depression almost doubled between 2017 and…
- Conditions
- Depressive Disorder, Generalized Anxiety Disorder, Suicidal Ideation
- Trial name
- QUALIPEPSY (NCT07719816)
- Testing
- Semi-structured interviews
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Suicide Risk
MIN PLAN VS CBT for Suicide Prevention
1. To investigate the effectiveness of Young Adults Culturally Adapted Manual Assisted Psychological Therapy (YA-CMAP) in University students with Suicide Risk 2.
- Trial name
- NCT05095233
- Testing
- Young Adults Culturally Adapted Manual Assisted Psychological Therapy (YA-CMAP), Min Plan Tool
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Syeda AYAT E ZAINAB Ali
PTSD, PTSD - Post Traumatic Stress Disorder
Assessing of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies
PRE-EMPT will assemble a cohort of 150 participants from three populations (low risk, intermediate risk, and high risk for self-harm).
- Conditions
- PTSD, PTSD - Post Traumatic Stress Disorder, Major Depression, Suicidality
- Trial name
- PRE-EMPT (NCT07745569)
- Testing
- Transcranial Magnetic Stimulation, Psilocybin (drug), Neurofeedback
- Volunteers
- 150 people
- Sponsor
- University of New Mexico
Suicide, Suicide Prevention
Focused Suicide Prevention Strategy for Youth Presenting to the Emergency Department With Suicide Related Behaviour
Suicide is the leading cause of death due to illness among Canadian youth, claiming more lives than any medical illness, including cancer. Suicide prevention is possible, and early intervention is needed.
- Conditions
- Suicide, Suicide Prevention, Suicidal Ideation, Self-Injurious Behavior
- Trial name
- IAMSAFE (NCT06225661)
- Testing
- SAFE Intervention, NAV (Telephone Navigation)
- Where
- 4 sites in Canada
- Volunteers
- 330 people
- Sponsor
- The Hospital for Sick Children