Clinical trials: Suicide, Ideation
Suicidal Ideation, Suicide, Attempted
Stepped Approach to Reducing Risk of Suicide in Primary Care
Suicide is the second leading cause of death among young people aged 12-17 years in the United States, yet many youth at risk for suicide are not identified or go untreated.
- Conditions
- Suicidal Ideation, Suicide, Attempted, Suicide Prevention
- Trial name
- STARRS-PC (NCT06018285)
- Testing
- Stepped Approach to Reducing Risk of Suicide in Primary Care
- Where
- 15 sites in United States
- Volunteers
- 2,572 people
- Sponsor
- Cynthia Fontanella
Depression, Anxiety
Mental Health First Aid for College Students
Most college students with mental disorders do not receive treatment, and over 80% of those who die by suicide have never made contact with campus mental health services.
- Conditions
- Depression, Anxiety, Suicidal Ideation, Eating Disorders
- Trial name
- NCT02021344
- Testing
- Mental Health First Aid
- Where
- United States
- Volunteers
- 2,543 people
- Sponsor
- University of Michigan
Suicide, Attempted, Suicide Ideation
Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings
The study will compare the effectiveness of two relatively brief and scalable evidence-based interventions: the Stanley Brown Safety Planning Intervention and Follow-up Contacts (SPI+), a suicide-specific intervention that helps…
- Conditions
- Suicide, Attempted, Suicide Ideation, Suicide, Suicide Prevention
- Trial name
- NCT06151158
- Testing
- Stanley Brown Safety Planning Intervention and Follow-up Contacts (SPI+), Interpersonal Psychotherapy for Adolescents Ultra Short Crisis Intervention (IPT-A SCI)
- Where
- 6 sites in United States
- Volunteers
- 484 people
- Sponsor
- Johns Hopkins University
Suicide, Attempted, Suicidal Ideation
Motivational Interviewing to Address Suicidal Ideation for Veterans at High Risk for Suicide
The purpose of this project is to conduct a randomized control trial with 470 Veterans to examine the impact of a revised version of Motivational Interviewing to Address Suicidal Ideation (MI-SI-R) on risk for suicide attempts…
- Trial name
- MI-SI (NCT05256940)
- Testing
- Motivational Interviewing to Address Suicidal Ideation- Revised (MI-SI-R), Enhanced usual care (EUC)
- Where
- 3 sites in United States
- Volunteers
- 368 people
- Sponsor
- VA Office of Research and Development
Suicidal Ideation, Suicide, Attempted
Suicide Prevention in Prepubertal Children
Suicidal ideation and behaviors are estimated to be as high as 4-16% and 1.5% (respectively) in the general 6-12-year-old population.
- Trial name
- NCT04171089
- Testing
- Child- Safety Plan Intervention
- Where
- United States
- Sponsor
- New York State Psychiatric Institute
Depression
Improving Mood in Veterans in Primary Care
The purpose of the Improving Mood in Veterans in Primary Care (IIR 14-047) is to evaluate a brief educational individual workshop that is meant to help Veterans better understand feelings of sadness and ways to improve their…
- Trial name
- NCT02276807
- Testing
- Brief Behavioral Activation, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 140 people
- Sponsor
- VA Office of Research and Development
Suicidal Ideation, Suicide, Attempted
A Conditioning Paradigm to Increase Affinity for Sacredness of Life
Suicide-related experiences affect millions of people every year in the United States. Through decades of research, interventions targeting these experiences have developed with varied empirical support.
- Conditions
- Suicidal Ideation, Suicide, Attempted, Suicide and Self-harm, Non-suicidal Self-injury
- Trial name
- NCT05541900
- Testing
- TEC-Sacredness, TEC-Control
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Florida State University
Suicide, Suicide Ideation
Randomized Suicide Prevention Trial Using ASSIP and ACT in Suicide Attempters
This is a randomized controlled trial that aims to compare the effectiveness of two psychological treatment approaches: the Attempted Suicide Short Intervention Program (ASSIP) and Acceptance and Commitment Therapy (ACT).
- Trial name
- NCT07132099
- Testing
- Attempted Suicide Short Intervention Program (ASSIP), Acceptance and Commitment Therapy (ACT), Treatment as Usual (TAU)
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Ardakan University
Suicidal Ideation, Suicidal Behavior
Integrated Suicide Supports and Safety Planning for Youth
The goal of this clinical trial is to evaluate an app to help keep teens and young adults with suicidal thoughts safe. The app includes a safety plan created by adolescents and healthcare providers, and videos to encourage…
- Trial name
- ISSP (NCT06701006)
- Testing
- Integrated skills and safety planning app
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Washington
Bipolar Depression, Suicidal Ideation
NRX101 Glx Biomarker Validation Study
Subnormal level of Glutamate+Glutamine (Glx) in the Anterior Cingulate Cortex (ACC) of the brain has been associated with depression and PTSD.
- Trial name
- NRX-GLX (NCT03402152)
- Testing
- NRX-101, Lurasidone HCl
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- NeuroRx, Inc.
Suicide, Suicide, Attempted
Suicide Prevention Among Recipients of Care
Randomized controlled trial to determine the best brief suicide prevention intervention for adults and adolescents who screen positive for suicidal ideation or behavior in emergency departments or primary care clinics.
- Conditions
- Suicide, Suicide, Attempted, Suicidal Ideation, Social Support
- Trial name
- SPARC (NCT04893447)
- Testing
- SPI+, SP+CC (Caring Contacts)
- Where
- United States
- Volunteers
- 1,520 people
- Sponsor
- St. Luke's Health System, Boise, Idaho
Suicidal Ideation, Suicidal Behavior
Multimodality Adaptive Intervention for Post-Inpatient Hospitalization Suicide Risk Reduction
The goal of this clinical trial is to learn whether a combination of brief digital and clinician-delivered interventions can help adults leaving a psychiatric hospitalization cope with suicidal thoughts and prevent…
- Trial name
- NCT06764108
- Testing
- Self-monitoring, JITAI, Self-guided SSI
- Volunteers
- 360 people
- Sponsor
- Massachusetts General Hospital
Transgender, Depression
Mental Health Support for Transgender and Gender-expansive Individuals
This study will evaluate an intervention's feasibility, acceptability and efficacy potential in a one-arm trial with Romanian transgender and gender diverse (e.g., gender non-binary) (TGD) individuals who report depression or…
- Conditions
- Transgender, Depression, Anxiety, Suicidality
- Trial name
- NCT06229132
- Testing
- LGBTQ-affirmative CBT for transgender individuals
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Columbia University
Insomnia, Suicidal Ideation
A Sleep-Oriented Intervention for Suicidal Behaviors
An open-label trial to investigate the use of a behavioral insomnia treatment for suicidal ideation.
- Trial name
- NCT01770587
- Testing
- Behavioral Insomnia Treatment
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Stanford University
Suicide Ideation, Depressed
Supplementing Inpatient Behavioral Activation Group Psychotherapy
This study will evaluate the feasibility, acceptability, and preliminary effectiveness of a behavioral activation intervention designed for adults hospitalized on an inpatient psychiatric unit.
- Trial name
- NCT07611916
- Testing
- Behavioral Activation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Rutgers, The State University of New Jersey
Suicide, Suicidal
Safe Treatment for Emergency Presentation for Suicidal Ideation and Behavior in Youth
This randomized comparative effectiveness trial will compare two evidence-based approaches to emergency care for youth ages 13-24 who present to the Emergency Department (ED) with suicidal ideation or behavior.
- Conditions
- Suicide, Suicidal, Self-Harm
- Trial name
- SAFE STEPS (NCT05304065)
- Testing
- SAFETY-A within usual ED Care, Combined SAFETY-A within usual ED Care + CLASP Therapeutic Follow-Up Contacts
- Where
- 5 sites in United States
- Volunteers
- 1,600 people
- Sponsor
- University of California, Los Angeles
Mental Health Wellness 1
Assessing Online Interventions for Men's' Mental Health and Wellbeing
The purpose of this study is to test a comprehensive, male-oriented, online screening and referral (Screening for Mental Health; SMH) and male-oriented online information and referral intervention program (Man Therapy; MT) to…
- Trial name
- NCT02785471
- Testing
- Screening for Mental Health only, Screening for Mental Health & Man Therapy
- Where
- United States
- Volunteers
- 554 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Borderline Personality Disorder
Effectiveness of a 24 Hour Phone Line on the Rate of Suicide Attempts in Borderline Patients
This randomized multicentric clinical trial assesses the effectiveness of 24 hour phone line on the rate of suicide attempts and self-injurious behaviors in borderline patients.
- Trial name
- NCT00603421
- Testing
- 24 hour phone line, treatment as usual
- Where
- 2 sites in France
- Volunteers
- 318 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
PTSD, Suicidal Thoughts and Behaviors
Cannabis, Neuroinflammation, and Suicidal Ideation: A Supplemental Brain Imaging Study
This study will be the first to use brain imaging to explore how cannabis affects the brain and inflammation in U.S. military veterans with PTSD.
- Conditions
- PTSD, Suicidal Thoughts and Behaviors, PTSD Symptoms, Depressive Symptoms
- Trial name
- CNS (NCT07222306)
- Testing
- 1-(2-[+F]fluoroethyl)-L-tryptophan
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wayne State University
Suicidal Ideation
Suicide Treatment Alternatives for Teens
Quasi-Randomized trial to compare inpatient care versus outpatient crisis intervention clinic. This study plans to enroll up to 1,000 participants across 4 sites in a 5 years period.
- Trial name
- START (NCT04089254)
- Testing
- Inpatient Psychiatry, Outpatient Crisis Intervention Clinic
- Where
- 4 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati