Clinical trials: Suicide, Ideation
Alcohol Use Disorder (AUD), Suicidal Ideation
Examining the Relationship Between Ongoing Alcohol Use, Suicidal Thoughts and Behaviors and Related Constructs, and Behavioral Economic Decision-Making.
This study will evaluate the relationship between alcohol use, suicidal thoughts and behaviors, and behavioral economic decision-making.
- Trial name
- NCT07842588
- Testing
- CBT4CBT
- Volunteers
- 180 people
- Sponsor
- Mark J Rzeszutek, PhD
Suicide, Attempted, Suicidal Ideation
A Study of a Smartphone-based Intervention for Suicidal Inpatients
Suicide is the most common form of deadly violence. Indeed, since more than 40,000 people die by suicide each year, people are 2.5 times more likely to die by their own hand than someone else's.
- Conditions
- Suicide, Attempted, Suicidal Ideation, Hopeless
- Trial name
- NCT03121742
- Testing
- Ecological Momentary Intervention, Treatment as Usual
- Sponsor
- Rutgers, The State University of New Jersey
Suicidal Ideation
Ketamine Infusion for Rapid Reduction of Suicidality in Pediatrics
Suicide is a leading cause of death for children and adolescents. Since warning signs of suicide and links to precipitating events differ between age groups, suicide can be difficult to predict.
- Trial name
- Keta4SI (NCT04955470)
- Testing
- Ketamine Injectable Solution, Midazolam Injectable Solution, Normal Saline 0.9% Injectable Solution
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of British Columbia
Depression, Suicidal Ideation
Engaging Black Youth in Depression and Suicide Prevention Treatment Within Urban Schools
Completing evidence-based treatments for depression has been shown to be particularly problematic for Black adolescents. If Black adolescents' depression treatment needs are to be met, the engagement challenges and the factors…
- Trial name
- NCT03940508
- Testing
- Making Connections Intervention, IPT-A
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- New York University
Major Depressive Disorder
Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression
The study will consist of a 24-week-long trial examining outcomes in patients with Major Depressive Disorder and suicidal ideation who will receive intravenous (IV) ketamine and intranasal (IN) esketamine, compared to a large…
- Trial name
- NCT05450432
- Testing
- Ketamine, Esketamine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Suicidal Ideation and Behavior
Design and Feasibility of an SMS-based Safety Planning Intervention
This study is testing whether it is feasible to run a larger randomized controlled trial and whether an automated text messaging program is acceptable to young adults who have suicidal thoughts.
- Trial name
- NCT07365579
- Testing
- Text Messaging based Safety Planning Intervention, Facilitated Referral to Crisis Resources
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwestern University
Suicidal Ideation, Alcohol Drinking
Computerized DBT Skills Training for Suicidal and Heavy Episodic Drinkers
Alcohol use is considered to be a significant risk factor among those who die by suicide, especially among those who drink to regulate their emotions.
- Trial name
- NCT02932241
- Testing
- Computerized Dialectical Behavior Therapy Skills Training
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Washington
Suicidal Ideation
Digital Narrative Bibliotherapy as a Scalable Intervention for Suicidal Thoughts
The goal of this study was to determine whether reading about others' experiences with suicide can help reduce suicidal thoughts. To investigate this issue, the investigators recruited users from an internet support community.
- Trial name
- NCT05351645
- Testing
- Treatment
- Where
- United States
- Volunteers
- 864 people, healthy volunteers welcome
- Sponsor
- Harvard University
Posttraumatic Stress Disorder, Depression
A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity
The overarching goal of this UH2-UH3 proposal is to work with the NIH Health Care Systems Research Collaboratory to develop and implement a large scale, cluster randomized pragmatic clinical trial demonstration project that…
- Conditions
- Posttraumatic Stress Disorder, Depression, Alcohol-Related Disorders, Suicidal Ideation
- Trial name
- TSOS6 (NCT02655354)
- Testing
- Motivational Interviewing, Cognitive Behavioral Therapy Elements, Care Management
- Where
- 24 sites in United States
- Volunteers
- 635 people
- Sponsor
- University of Washington
Suicidal Ideation, Suicidal Ideation and Behaviors
Transformative Mixed Evaluation of a Suicide Attempt Recovery Intervention
This study aims to evaluate the impact of a brief clinical group intervention based on the recovery model aimed at adult repeat suicide attempters attending an outpatient unit belonging to a public hospital in the Maule region…
- Trial name
- NCT06686498
- Testing
- Illness Management and Recovery adapted to suicidal behavior (IMR-ACS)
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- Oriana Arellano Faúndez
Glioblastoma (GBM)
Mental Health and Suicidality in Glioblastoma Patients in Germany
The aim of the study is to use standardized questionnaires to systematically record influencing factors or predictors for suicidal behavior in glioblastoma patients, particularly with regard to existing depression and anxiety…
- Trial name
- SHINE-GLIO (NCT07409584)
- Testing
- Medical history, physical examination, completing questionnaires, data collection
- Where
- 6 sites in Germany
- Volunteers
- 180 people
- Sponsor
- University Hospital, Essen
Autism Spectrum Disorder, Regulation, Self
Development of Self-regulation by Dialectial Behavioural Therapy in Adults With Autism
Individuals with autism spectrum disorder (ASD) are at risk to develop more pervasive emotion-dysregulation. In this study experiences of adults with ASD and severe emotion dysregulation with Integrative Dialectical Behaviour…
- Trial name
- DASHBOARD (NCT05502484)
- Testing
- Integrative Dialectical Behavioural Therapy (DBT)
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Radboud University Medical Center
Depression, Unipolar Depression
Confirmatory Efficacy and Safety Trial of Magnetic Seizure Therapy for Depression
This trial aims to assess the efficacy and tolerability of Magnetic Seizure Therapy (MST) as an alternative to electroconvulsive therapy (ECT) for depression.
- Conditions
- Depression, Unipolar Depression, Treatment Resistant Depression
- Trial name
- CREST-MST (NCT03191058)
- Testing
- Magnetic Seizure Therapy, Electroconvulsive Therapy
- Where
- 3 sites in United States, Canada
- Volunteers
- 239 people
- Sponsor
- University of Texas Southwestern Medical Center
Reintegration Difficulties, Suicidal Ideation and Behaviors
Expanding Veteran Sponsorship Initiative+ to Support High-Risk Transitioning Servicemembers and Veterans: A Precision Medicine Approach
Background Young Veterans in the U.S. face a heightened risk of suicide, particularly during the first year after leaving military service-a period often referred to as the "deadly gap." Suicide rates among Veterans aged 18 to 34…
- Conditions
- Reintegration Difficulties, Suicidal Ideation and Behaviors, Health, Connectedness
- Trial name
- NCT07356492
- Testing
- Onward Ops- receive peer sponsor and community support, VA stepped care services
- Where
- United States
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Suicidal Ideation, Suicide Attempt
Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part A
This Study will comprehensively evaluate a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self Harm
- Trial name
- Jaspr-PartA (NCT06223867)
- Testing
- Jaspr App + JAH, ETAU
- Where
- United States
- Volunteers
- 670 people
- Sponsor
- University of Massachusetts, Worcester
Suicide
Ketamine for Acute Suicidal Ideation in the Emergency Department: Randomized Controlled Trial
This study will enroll patients presenting to the emergency department with acute suicidal ideation meeting inclusion and exclusion criteria.
- Trial name
- LDK-SI (NCT01892995)
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Suicidal Thoughts, Sexual and Gender Minorities
Piloting a Brief, Online Intervention for Suicidality in Sexual and Gender Minority Youth
Sexual and gender minority youth (i.e., LGBTQ+ individuals) are at elevated risk for suicidal thoughts compared to cisgender/heterosexual youth and there is increased demand for programs and treatments tailored to this…
- Conditions
- Suicidal Thoughts, Sexual and Gender Minorities, Youth
- Trial name
- NCT07402265
- Testing
- KindMind
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Western University
Suicide, Mental Health Disorder
A Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents
Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death amongst youth. Digital tools, especially personal smartphones, are promising avenues to address these issues and can be…
- Conditions
- Suicide, Mental Health Disorder, Anhedonia
- Trial name
- ViraSafeRCT (NCT07348666)
- Testing
- ViraSafe: Treatment pushes, BRITE
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Ksana Health
Suicidal Behaviors, Suicide Ideation
Examining the Efficacy of a Digital Therapeutic to Prevent Suicidal Behaviors
The primary aim of the project is to test the efficacy of BCBT delivered via a digital platform (i.e., smartphone) to Servicemembers with recent suicidal ideation and/or suicide attempts presenting to primary care clinics.
- Conditions
- Suicidal Behaviors, Suicide Ideation, Depression/Anxiety
- Trial name
- NCT06318962
- Testing
- Aviva
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Memphis
Suicidal Ideation, Suicidal Behaviors
Pilot Study of a Modified Safety Planning Intervention for Elementary School-Aged Children - Main Study
The goal of this study is to finalize a version of the Safety Planning Intervention suitable for 6-12-year-old children. This intervention provides individuals with strategies to reduce the risk of suicidal behavior.
- Trial name
- NCT07564583
- Testing
- Child - Safety Planning Intervention, C-SPI+ecological momentary assessment
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Columbia University