Clinical trials: Suicide; Trauma
Suicidal Ideation, Depressive Disorder
Reducing Suicide Risk in Older Veterans Using Problem Solving Therapy
Suicide is a national crisis, especially among older Veterans for whom evidence-based suicide prevention efforts are lacking. This proposal responds to the national priority to develop and improve interventions for suicide…
- Conditions
- Suicidal Ideation, Depressive Disorder, Anxiety Disorders, Post Traumatic Stress Disorder
- Trial name
- NCT04763330
- Testing
- Enhanced Usual Care (EUC), Problem Solving Therapy (PST) plus EUC
- Where
- 2 sites in United States
- Volunteers
- 117 people
- Sponsor
- VA Office of Research and Development
Trauma, PTSD
Posttraumatic Stress Symptoms Among Rescuers at Risk
This cross-sectional, anonymous online survey aims to examine how salient variables influence PTSS, well-being, and suicidal ideation across the following professions of rescue workers: firefighters, ambulance personnel, police…
- Conditions
- Trauma, PTSD, Self Efficacy, Coping Skills
- Trial name
- NCT03842553
- Testing
- No Intervention: anonymous online survey
- Where
- Switzerland
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- University of Bern
Mild Traumatic Brain Injury, Hyperbaric Oxygen Therapy
Treatment of U.S. Veterans With Mild Traumatic Brain Injury With Hyperbaric Oxygen Therapy
Mild traumatic brain (mTBI) injury affects 400,000 U.S. Veterans resulting in physical, cognitive and mental health symptoms. The Department of Defense (DoD) reported 26 suicides a day from mTBI despite ongoing care for the…
- Conditions
- Mild Traumatic Brain Injury, Hyperbaric Oxygen Therapy, Depression
- Trial name
- NCT06665633
- Testing
- Oxygen 100 % Gas for Inhalation, Hyperbaric Oxygen Therapy Chamber
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Nova Southeastern University
Depression, Stress Disorders, Post-Traumatic
Effectiveness and Implementation of eScreening in Post 9/11 Transition Programs
Electronic screening is effective for timely detection of, and intervention for, suicidal ideation and other mental health symptoms.
- Conditions
- Depression, Stress Disorders, Post-Traumatic, Suicide
- Trial name
- NCT04506164
- Testing
- eScreening, Screening As Usual
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Post Traumatic Concerns, Post Traumatic Stress Disorder
A Comparative Effectiveness Trial of Optimal Patient-Centered Care
The nation's trauma care system, which includes trauma center hospitals \& emergency departments, is where over 30 million Americans receive care after traumatic injuries each year.
- Conditions
- Post Traumatic Concerns, Post Traumatic Stress Disorder, Depression and Suicide Ideation, Alcohol and Drug Use
- Trial name
- TSOS 5 (NCT02274688)
- Testing
- Stepped Care Management
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- University of Washington
Suicide, Firearm Injury
Home Safety Intervention
Access to lethal methods of self-harm such as firearms and medications increases risk for suicide. As such, VA/DoD guidelines for the care of individuals with elevated suicide risk include recommendations that clinicians deliver…
- Conditions
- Suicide, Firearm Injury, Overdose
- Trial name
- HSI (NCT06216327)
- Testing
- household safety intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- VA Office of Research and Development
Post-traumatic Stress Disorder, Traumatic Brain Injury
Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop
In this proposal, the investigators extend their previous SPiRE feasibility and preliminary effectiveness study to examine STEP-Home efficacy in a RCT design.
- Conditions
- Post-traumatic Stress Disorder, Traumatic Brain Injury, Substance Related Disorders, Depression
- Trial name
- STEP-Home (NCT03868930)
- Testing
- STEP-Home, PCGT
- Where
- 2 sites in United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Major Depressive Episode (MDE), Major Depressive Disorder (MDD)
LHC-CIDI-5 in Hong Kong
The World Health Organization Composite International Diagnostic Interview-5th (CIDI-5) is a standardized diagnostic tool used to assess the prevalence of mental and substance use disorders over varying time frames (30 days, 12…
- Conditions
- Major Depressive Episode (MDE), Major Depressive Disorder (MDD), Persistent Depressive Disorder (PDD), Suicidal Ideation
- Trial name
- NCT06804525
- Testing
- CIDI-5, LHC-CIDI-5
- Where
- Hong Kong
- Volunteers
- 2,500 people
- Sponsor
- The University of Hong Kong
Grief, Post Traumatic Stress Disorder
Walk With Me (WWM) for Perinatal Grief
The goal of this clinical trial is to learn if the Along With Me web-based intervention works to decrease posttraumatic stress symptoms and suicidal ideation among bereaved parents following pregnancy and early infant loss.
- Conditions
- Grief, Post Traumatic Stress Disorder, Suicidal Ideation, Miscarriage
- Trial name
- PeriGrief-II (NCT07011940)
- Testing
- Along With Me, Peer Guide
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Insomnia, Depression
Adjunctive Brief Behavioral Treatment of Insomnia (BBTI) for Sleep Intervention (SI)
There is a strong association between sleep disturbance and suicidal thoughts and behaviors. Sleep disturbance is also highly comorbid with other common conditions associated with suicide such as depression and posttraumatic…
- Conditions
- Insomnia, Depression, Posttraumatic Stress Disorder, Suicidal Ideation
- Trial name
- NCT02248675
- Testing
- CBT-I, TAU
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- VA Office of Research and Development
Mild Traumatic Brain Injury, Suicidal Ideation
Frontal iTBS for Impulsivity and Suicidal Ideation in Veterans With Mild Traumatic Brain Injury
The investigators hope to develop a treatment for suicidal ideation (SI), impulsivity and functional impairments (such as difficulties in social and work settings) that occur after a mild traumatic brain injury (mTBI).
- Conditions
- Mild Traumatic Brain Injury, Suicidal Ideation, Impulsivity
- Trial name
- NCT05647044
- Testing
- intermittent theta burst stimulation
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- VA Office of Research and Development
Suicidal Ideation
Precision Phenotyping of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies
PRE-EMPT will assemble a study group of 150 civilian and Veteran participants from three populations (low risk, intermediate risk, and high risk for self-harm).
- Trial name
- PRE-EMPT (NCT07484906)
- Testing
- fMRI Neurofeedback, Accelerated theta burst stimulation, Psilocybin assisted therapy
- Sponsor
- University of New Mexico