Clinical trials: Suicide
Suicide Mortality
The Developmental Origins of Suicide Mortality
Background: Suicide rates are rising. In 2013, it was the third leading cause of death in children ages 10-14. It was the second leading cause of death for ages 15-24. Many risk factors for suicide have been found.
- Trial name
- NCT03027440
- Where
- United States
- Volunteers
- 52,966 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Assisted Suicide
Assisted Suicide in Switzerland
Background: Researchers want to learn more about how the Swiss model of assisted suicide works. To do this, they have interviewed 25 Swiss experts.
- Trial name
- NCT04261088
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Suicide
Rapid Personalization of Safety Plans for Psychiatrically Hospitalized Veterans at High-Risk for Suicide
Veterans psychiatrically hospitalized face significantly elevated suicide risk, particularly in the three months post-discharge.
- Trial name
- NCT07507786
- Testing
- Personalized Safety Plans, Safety Plans as Usual + Calls
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- VA Office of Research and Development
Psychosis, Suicide
Targeting Emotion Dysregulation to Reduce Suicide in People With Psychosis
People with psychotic disorders are excluded from most suicide-focused clinical trials despite incredibly high rates of completed suicide, and interventions that have been tested for this population have shown limited impact on…
- Trial name
- NCT05440214
- Testing
- Dialectical Behavior Therapy Skills Training
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Maryland, Baltimore
Suicide, Attempted
Skills to Enhance Positivity in Suicidal Youth
This is a Hybrid Type I Effectiveness-Implementation design. Specifically, this study proposes to test the effectiveness of STEP in reducing suicidal events and ideation in 216 adolescents, admitted to inpatient psychiatric care…
- Trial name
- STEP (NCT04994873)
- Testing
- STEP, Enhanced TAU
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Brown University
Caregivers, Suicide
A Pilot Study of a DBT-Informed Caregiver Risk Management Workshop
The goal of this pilot clinical trial is to explore the feasibility and acceptability of implementing an intervention for caregivers in our health care system.
- Conditions
- Caregivers, Suicide, Nonsuicidal Self Injury, Adolescent
- Trial name
- NCT07852429
- Testing
- Workshop and consultation for caregivers of at risk youth
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Suicide, Suicide Attempt
Expanding Access to Evidence-Based Suicide Risk Assessment and Intervention in a Crisis Stabilization Setting
The overarching goal of this project is to expand access to evidence-based suicide risk assessment, safety planning, and intervention among patients at elevated suicide risk by implementing Jaspr in a real-world psychiatric…
- Conditions
- Suicide, Suicide Attempt, Randomized Controlled Trial (RCT)
- Trial name
- NCT07864961
- Testing
- Jaspr
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Butler Hospital
Suicidal Ideation, Suicide
Cognitive Reappraisal Intervention for Suicide Prevention (CRISP 70+) for Suicidal Older Adults in a Swedish Geropsychiatric Setting
The overall aim of the project is to develop and test the feasibility and preliminary effect of a manualized psychosocial intervention Cognitive Reappraisal Intervention for Suicide Prevention (CRISP 70+) for older adults with…
- Conditions
- Suicidal Ideation, Suicide, Suicide Attempt
- Trial name
- NCT07866079
- Testing
- CRISP 70+
- Where
- Sweden
- Volunteers
- 19 people
- Sponsor
- Vastra Gotaland Region
Suicidal Ideation, Suicide Attempt
Youth Suicide Prevention: CAMS-BI vs. Safety Planning in a Randomized Trial
This study outlines a randomized controlled trial evaluating two brief suicide-specific interventions for adolescents aged 12-17 who are hospitalized for suicidal ideation or attempts.
- Conditions
- Suicidal Ideation, Suicide Attempt, Safety Plan, Depression / Major Depressive Disorder
- Trial name
- NCT07628192
- Testing
- CAMS Brief Intervention, Stanley-Brown Safety Planning Intervention
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- The Cleveland Clinic
Major Depressive Disorder, Suicide
i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial
Approximately four thousand Canadians die by suicide every year, and suicide is the second leading cause of death in youth and young adults (15-34 years).
- Conditions
- Major Depressive Disorder, Suicide, Treatment Resistant Depression
- Trial name
- Ket-CBT (NCT06480500)
- Testing
- Ketamine hydrochloride, i-CBT (Internet-based Cognitive Behavioural Therapy), Midazolam Hydrochloride
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- University Health Network, Toronto
Suicide Ideation
Nurse and Peer Led Suicide Prevention in Tajikistan
The study takes place in Tajikistan, a postwar country in Central Asia, where Dr. Weine, Dr. Pirova, Dr. Bahromov, and other collaborators successfully implemented a D43 research capacity building project and an R21 and R01 on…
- Trial name
- NCT07453758
- Testing
- Suicide prevention treatment, Care as usual
- Where
- Tajikistan
- Volunteers
- 96 people
- Sponsor
- University of Illinois at Chicago
Battered Women, Suicide, Attempted
Effectiveness of Empowerment Group Sessions for Treating Suicidal African American Women in Abusive Relationships
This study will evaluate the effectiveness of culturally competent psychoeducational empowerment sessions in treating suicidal African-American women who are in abusive relationships.
- Trial name
- NCT00601939
- Testing
- Psychoeducational intervention (PEI), Enhanced treatment as usual (ETAU)
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- Emory University
Suicide
A Pilot Evaluation of a Digital Peer Support Intervention for Suicidal Adolescents
Suicide risk has increased among youth in underserved communities, where access to mental healthcare is limited. To address this need, the investigator team plans to evaluate the preliminary efficacy of a brief, low-cost…
- Trial name
- SWEEP (NCT06349915)
- Testing
- Supporting Wellbeing with Everyday Experiences of Peers (SWEEP)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Albert Einstein College of Medicine
Suicide, Depressive Disorder, Treatment-Resistant
Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression
Background: Major depressive disorder (MDD) is a serious mental illness that can put people at risk of self-harm and death. Many drugs are used to treat MDD, but it can take a long time for them to be effective.
- Conditions
- Suicide, Depressive Disorder, Treatment-Resistant, Ketamine, Molecular Mechanisms of Pharmacological Action
- Trial name
- NCT06511908
- Testing
- (2R,6R)-hydroxynorketamine (0.25 to 2.0 mg/kg)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Mental Health (NIMH)
Suicidal Ideation and Behavior, Mood Disorders
Videoconference-Based Brief Cognitive Behavioral Therapy for Patients With Mood Disorders at High Risk for Suicide
This study aims to investigate inflammatory biomarkers associated with suicide risk and to evaluate the efficacy of videoconference-based brief cognitive-behavioral therapy (V-BCBT) in patients with mood disorders at high risk…
- Conditions
- Suicidal Ideation and Behavior, Mood Disorders, Suicide Attempt, Cognitive Behavior Therapy
- Trial name
- V-BCBT-BIO (NCT07857291)
- Testing
- Videoconference-Based Brief Cognitive Behavioral Therapy, Treatment as Usual (TAU)
- Where
- South Korea
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Hyung Keun Park
Mental Health Disorder, Suicide Attempt
Improving Care, Accelerating Recovery and Education
The goal of this clinical trial is to test the I-CARE program in children who are in a medical hospital awaiting inpatient mental health treatment.
- Conditions
- Mental Health Disorder, Suicide Attempt, Suicidal Ideation, Emergency Psychiatric
- Trial name
- I-CARE (NCT06233747)
- Testing
- Improving Care, Accelerating Recovery & Education (ICARE)
- Where
- 2 sites in United States
- Volunteers
- 89 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Suicidal Ideation, Suicide Attempt
Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part B
This Study will evaluate the implementation of a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self Harm
- Trial name
- Jaspr-PartB (NCT06311591)
- Testing
- Jaspr App
- Where
- 4 sites in United States
- Volunteers
- 27,908 people
- Sponsor
- University of Massachusetts, Worcester
Suicide Prevention, Suicide
NIMH Clinical Pathway in Rural Appalachian School-based Health Clinics
This study will adapt and evaluate an evidence-based suicide risk screening and follow-up program in two school-based health centers in West Virginia.
- Trial name
- NCT06808503
- Testing
- NIMH Clinical Pathway
- Where
- 3 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Suicide, Attempted, Suicide, Completed
Virtual Reality Lethal Means Safety Training
The goal of this randomized clinical trial is to determine whether a virtual reality (VR) training program can help healthcare providers improve their skills in discussing suicide prevention and safe storage of firearms and…
- Conditions
- Suicide, Attempted, Suicide, Completed, Suicide Prevention, Mental Health Training
- Trial name
- NCT07219355
- Testing
- Virtual Reality Lethal Means Safety Training, 2D Video Training
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Suicide Ideation, Suicide Attempt
Plan and Protect: Safety Planning for Teens in Rural Emergency Departments
The goal of this observational study is to determine whether implementing a culturally sensitive, tablet-based safety planning program called Plan \& Protect (P\&P) within rural emergency departments can improve home safety and…
- Trial name
- NCT07325474
- Testing
- Plan & Protect safety planning intervention, Care as usual
- Where
- 6 sites in United States
- Volunteers
- 550 people
- Sponsor
- Dartmouth-Hitchcock Medical Center