Clinical trials: Suicide Behavior
Cannabis Use, Depression
Cannabis, Linked Emotions, and Adolescent Risk Study
The goal of this study is to disentangle relationships between acute cannabis use and withdrawal on proximal depression and suicide risk and recovery in adolescents ages 12-18 years by incorporating time-varying patterns of…
- Conditions
- Cannabis Use, Depression, Suicidal Ideation, Adolescent Behavior
- Trial name
- CLEAR (NCT06576076)
- Testing
- Contingency management for cannabis abstinence
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Massachusetts General Hospital
Suicide
Evaluation of a Gatekeeper Training for Pharmacists
This study aims to investigate to what extent a gatekeeper training (e-learning) for pharmacists and PTA is effective in changing the attitudes, knowledge, and self-efficacy.
- Trial name
- NCT05991635
- Testing
- Gatekeeper training (e-learning)
- Where
- Belgium
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- University Ghent
Depression, Suicidal Ideation
Treatment of Suicidal Ideation With Intravenous Ketamine Infusion
This study is dedicated to achieving better treatments for suicidal thoughts. Specifically, the investigators are studying the effect of a medication called ketamine to quickly treat suicidal thoughts and depression.
- Trial name
- NCT01887990
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Alabama at Birmingham
Suicidal Intention, Suicidal Ideation
Men and Providers Preventing Suicide (MAPS)
This study will determine if suicidal middle-aged men who use a personalized computer program addressing suicide risk before a primary care visit are more likely to discuss suicide and accept treatment, reducing their suicide…
- Conditions
- Suicidal Intention, Suicidal Ideation, Suicide, Attempted
- Trial name
- NCT02986113
- Testing
- MAPS tailored multimedia patient activation program, Sleep hygiene video, Telephone evidence-based follow-up care
- Where
- 2 sites in United States
- Volunteers
- 93 people
- Sponsor
- University of California, Davis
Suicidal Ideation, Suicidal Behaviors
Pilot RCT of a Video-based Intervention for Suicide Prevention
The investigators will develop a brief video-based intervention for suicide prevention, called LifePlans. LifePlans will be tested in a pilot randomized controlled trial (n = 40) to examine its feasibility and acceptability.
- Conditions
- Suicidal Ideation, Suicidal Behaviors, Suicide
- Trial name
- NCT05127330
- Testing
- LifePlans, Treatment as Usual
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Butler Hospital
Major Depressive Disorder, Major Depressive Episode
Universal vs. Targeted School Screening for Adolescent Major Depressive Disorder
The primary goal of the proposed study is to compare the effectiveness of universal school based screening for adolescent major depressive disorder to the current school process of targeted screening based on concerning behavior.
- Trial name
- NCT03716869
- Testing
- Universal Screening Arm
- Where
- United States
- Volunteers
- 12,909 people
- Sponsor
- Milton S. Hershey Medical Center
Anxiety, Depression Disorder
Screening and Monitoring of Mental Health in Educational Settings: Programme for Detection, Psychoeducation and Self-help
Adolescence is a critical developmental stage during which many mental health problems first emerge. However, a large proportion of these issues go undetected and untreated.
- Conditions
- Anxiety, Depression Disorder, Bullying, Addiction
- Trial name
- SENSE (NCT07818603)
- Testing
- program for the detection, referral, and psychoeducation in adolescents
- Where
- Spain
- Volunteers
- 436 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Suicidal Ideation, Suicide Attempt
Attempted Suicide Short Intervention Program for Older Adults (ASSIP-OA): An Evaluation of a Psychosocial Intervention for Suicidal Adults Aged 65+
Older adults are sorely underrepresented in suicide prevention research, despite the fact that suicide rates are higher in this age group than in any other age group in Sweden and in many countries worldwide.
- Conditions
- Suicidal Ideation, Suicide Attempt, Suicide
- Trial name
- NCT06831942
- Testing
- ASSIP-OA, Treatment as Usual (TAU)
- Where
- 2 sites in Sweden
- Volunteers
- 132 people
- Sponsor
- Vastra Gotaland Region
Suicidal Ideation Active, Suicidal and Self-injurious Behavior
Operation Worth Living Project With Suicidal Soldiers at Ft. Stewart
This is a randomized controlled trial comparing the use of new clinical intervention (the "Collaborative Assessment and Management of Suicidality--CAMS") versus enhanced care as usual for suicidal Soldiers who are seen at…
- Trial name
- OWL (NCT01300169)
- Testing
- The Collaborative Assessment and Management of Suicidality, Enhanced Care as Usual
- Volunteers
- 150 people
- Sponsor
- The Catholic University of America
Suicidal Ideation, Alcohol Drinking
Computerized DBT Skills Training for Suicidal and Heavy Episodic Drinkers
Alcohol use is considered to be a significant risk factor among those who die by suicide, especially among those who drink to regulate their emotions.
- Trial name
- NCT02932241
- Testing
- Computerized Dialectical Behavior Therapy Skills Training
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Washington
Depression
Risperidone and Suicidality in Major Depressive Disorder
The purpose of this trial is to investigate the efficacy of risperidone as an adjunct to an antidepressant treatment in the acute management of suicidality during an episode of major depressive disorder.
- Trial name
- NCT00167154
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Major Depressive Disorder, Smoking Reduction
Transcranial Magnetic Stimulation Theta Burst (TMS), Depression and Smoking.
This study evaluates de efficacy of Theta Burst Transcranial Magnetic Stimulation (TMS) applied on the left dorsolateral prefrontal cortex in patients with Major Depressive disorder and tobacco consumption.
- Trial name
- NCT05694754
- Testing
- Theta Burst Transcranial Magnetic Stimulation
- Where
- Mexico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dr. Julian Reyes López
Depressive Disorder, Major Depressive Disorder, Suicidal Ideation
Evaluation of a Multi-Layered Digital Phenotyping, Digital Safety Plan, and Pharmacogenomic Intervention for Suicide Prevention in Adults With Depression
The goal of this clinical trial is to learn if a multi-layered digital and pharmacogenomic intervention works to prevent suicide re-attempts in adults with depression.
- Conditions
- Depressive Disorder, Major Depressive Disorder, Suicidal Ideation, Suicide, Attempted, Suicide Prevention
- Trial name
- SMARTomicS (NCT07885722)
- Testing
- Digital Monitoring (Active/Passive EMA), Ecological Momentary Intervention (EMI) via Digital Safety Plan, Pharmacogenetic-Guided Care and Therapeutic Drug Monitoring
- Where
- Spain
- Volunteers
- 525 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Suicidal Ideation
(Cost)-Effectiveness of ABFT for Suicidal Youth.
Young adults who attempt to kill themselves is a common and serious mental health problem worldwide and certainly in Belgium and the Netherlands. Fatal suicide is the leading cause of death among young adults.
- Trial name
- REPAIR (NCT05965622)
- Testing
- Attachment Based Family Therapy (ABFT) + Treatment As Usual (TAU), Treatment As Usual (TAU)
- Where
- 13 sites in Belgium, Netherlands
- Volunteers
- 138 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Emotion Regulation
Testing an Intergenerational Model of Suicide Risk in Mother-child Dyads
The investigators are interested in learning more about how the role of mothers' emotions has on the transmission of suicide risk to children.
- Trial name
- NCT06463054
- Testing
- Dialectical Behavior Therapy Skills Group Training, Safety Planning Intervention
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Pittsburgh
Nonsuicidal Self-Injury, Self-Injurious Behavior
Naltrexone for Nonsuicidal Self-Injury
This randomized, double-blinded, placebo-controlled clinical trial aims to evaluate the efficacy and safety of naltrexone in reducing nonsuicidal self-injurious behavior among individuals with nonsuicidal self-injury.
- Trial name
- NCT07641283
- Testing
- Naltrexone 50mg (Whanin Naltrexone Tab. 50mg)
- Where
- 3 sites in South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Hospital
Depression
A Clinical Study of Trazodone Hydrochloride Prolonged-Release Tablets for Treatment of Depression
This is a multicenter, randomized, double-blind, parallel-group, placebo-controlled study to evaluate the efficacy and safety of trazodone hydrochloride prolonged-release tablets for treatment of depression in Chinese population.
- Trial name
- NCT01524497
- Testing
- Trazodone
- Where
- China
- Volunteers
- 382 people
- Sponsor
- Lee's Pharmaceutical Limited
Suicide, Co-design
Development of a Digital Acceptance and Commitment Therapy Intervention for Suicide Prevention in Adults Through Co-design
Suicide is a major public health concern and there is a need for accessible and scalable interventions to support individuals experiencing suicidal thoughts.
- Conditions
- Suicide, Co-design, Suicide Prevention
- Trial name
- NCT07733596
- Testing
- Digital ACT Intervention
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Hong Kong Polytechnic University
Stigma, Social, Mental Health Issue
Brief Interventions on Social Media to Reduce Suicide Risk (Intervention 2)
This clinical trial is part of a series of brief interventions to reduce suicide risk in collaboration with the social media platform RallyPoint, a site specifically designed for U.S.
- Trial name
- NCT06114862
- Testing
- Stigma-reduction intervention
- Where
- United States
- Sponsor
- Harvard University
Opioid Use, Opioid-use Disorder
Suicide Prediction and Prevention for People at Risk for Opioid Use Disorder: Supplement to COMPUTE 2.0
This study integrates the Mental Health Research Network (MHRN) suicide risk models into Opioid Wizard, an electronic health record (EHR) clinical decision support (CDS) to identify and treat patients at high risk of opioid use…
- Conditions
- Opioid Use, Opioid-use Disorder, Suicide
- Trial name
- NCT04939727
- Testing
- OUD-CDS + Suicide Risk Model associated CDS
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- HealthPartners Institute