Clinical trials: Suicide Risk, open to volunteers
Emotion Regulation
Testing an Intergenerational Model of Suicide Risk in Mother-child Dyads
The investigators are interested in learning more about how the role of mothers' emotions has on the transmission of suicide risk to children.
- Trial name
- NCT06463054
- Testing
- Dialectical Behavior Therapy Skills Group Training, Safety Planning Intervention
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Pittsburgh
Suicide, Mental Health Issue
Proximal Risk for Suicide in Adolescents
The central hypothesis is that biometric data can continuously monitor and allow for early identification/intervention of escalating suicidal symptoms.
- Trial name
- NCT06400810
- Testing
- Analog Devices Inc.
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Oregon Health and Science University
Major Depressive Disorder
Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression
The study will consist of a 24-week-long trial examining outcomes in patients with Major Depressive Disorder and suicidal ideation who will receive intravenous (IV) ketamine and intranasal (IN) esketamine, compared to a large…
- Trial name
- NCT05450432
- Testing
- Ketamine, Esketamine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Suicidal Ideas, Suicidal Ideation
A Pre-post Study of a Lethal Means Safety Planning Intervention for Youth at Elevated Suicide Risk in the Emergency Department
The purpose of this study is to test whether a lethal means safety planning intervention, TEEN LENS ED, is acceptable to teens at elevated suicide risk and their caregivers in the Emergency Department.
- Conditions
- Suicidal Ideas, Suicidal Ideation, Suicidal Thoughts, Firearm Safety
- Trial name
- TEEN LENS ED (NCT07916792)
- Testing
- TEEN LENS, Usual Care
- Volunteers
- 200 people
- Sponsor
- University of Colorado, Denver
Suicide Risk
Suicidal Risk in Adults in Panama: Validation of a Clinical Intervention Protocol
This study aims to validate MBT as an effective and viable intervention for implementation in public health services, with the potential to directly impact suicide prevention policies in the region.
- Trial name
- NCT07717320
- Testing
- Mentalization-Based Therapy (MBT), Treatment as Usual (TAU)
- Where
- 2 sites in Panama
- Volunteers
- 300 people
- Sponsor
- Fundación Judío Panameña (JUPA)
Insomnia, Suicidal Ideation
Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior
This study will test the effectiveness of a sleep-related primary suicide prevention program entitled TAILOR (Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior), which includes specific behavior-change…
- Conditions
- Insomnia, Suicidal Ideation, Suicide, Attempted
- Trial name
- TAILOR (NCT05390918)
- Testing
- TAILOR, Enhanced Usual Care
- Where
- United States
- Volunteers
- 235 people
- Sponsor
- Jeff Bridge
Suicide Prevention
Bridge the Gap (BTG) - Black Youth Group
The goal of this clinical trial is to develop and preliminarily test a culturally adapted suicide intervention specifically for black youth.
- Trial name
- Bridge the Gap (NCT06880809)
- Testing
- Bridge the Gap (BTG) - Black Youth Group
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Suicide Prevention
Evaluating Primary Suicide Prevention in Adolescents With Risk Factors
Suicide is one of the main causes of death among teenagers. Because it is preventable, primary prevention of suicide has become a public health priority, with encouraging results in promoting suicide awareness and reducing…
- Trial name
- ESPAIR (NCT06551038)
- Testing
- Primary suicide prevention intervention, Art-based control intervention
- Where
- 19 sites in Switzerland
- Volunteers
- 240 people
- Sponsor
- Stephanie Baggio
Caregivers, Suicide
A Pilot Study of a DBT-Informed Caregiver Risk Management Workshop
The goal of this pilot clinical trial is to explore the feasibility and acceptability of implementing an intervention for caregivers in our health care system.
- Conditions
- Caregivers, Suicide, Nonsuicidal Self Injury, Adolescent
- Trial name
- NCT07852429
- Testing
- Workshop and consultation for caregivers of at risk youth
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Suicidal Ideas, Suicidal Ideation
Couple-Based Crisis Safety Planning
Suicide is a leading cause of death in Veterans. Suicide rates among Veterans have increased approximately 36% from 2001 to 2020.
- Conditions
- Suicidal Ideas, Suicidal Ideation, Crisis; Emotional, Suicide Attempts
- Trial name
- CRP-C (NCT07012824)
- Testing
- Crisis Response Planning, Couples-based Crisis Response Planning
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Suicide Prevention
Caring Contacts Via Text Message for Suicidal Adolescents After Emergency Department Discharge
The goal of this pilot clinical trial is to learn if Caring Contacts (brief, hopeful, supportive text messages) can be delivered to adolescents with suicidal thoughts or behaviors after discharge from the emergency department…
- Trial name
- NCT07043764
- Testing
- Caring Contacts Text Messages
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Suicide Prevention, Suicide Safety Planning
Suicide Safety Planning
The goal of this clinical trial is to learn the best way to provide suicide prevention care to adults receiving outpatient mental health care.
- Conditions
- Suicide Prevention, Suicide Safety Planning, Suicidal Ideation, Suicide Attempt
- Trial name
- STAY (NCT07783490)
- Testing
- Local Care Continuity, Centralized Care Navigation
- Where
- United States
- Volunteers
- 176,000 people
- Sponsor
- Kaiser Permanente
Suicide Risk, Major Depressive Disorder (MDD)
Orexin Antagonism for Suicide Risk: A Proof-of-Concept Clinical Trial
The goal of this proof-of-concept clinical trial is to evaluate the initial safety, feasibility, and tolerability of the orexin mixed antagonist suvorexant in a sample of veteran adults with Major Depressive Disorder and elevated…
- Trial name
- NCT06854224
- Testing
- Suvorexant (dual orexin receptor antagonist)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Marianne Goodman
Suicidal Ideation
Effectiveness of the MindBridge Mobile Health Module for Young Adults at Risk of Suicide
This study will evaluate the effectiveness of MindBridge, a dialectical behavior therapy (DBT)-informed mobile health module delivered through a WeChat mini-program, among Chinese young adults aged 18 to 24 years with…
- Trial name
- MindBridge (NCT07767604)
- Testing
- MindBridge Mobile Health Intervention, Attention-Matched General Well-Being Program
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Jiangsu Medical College
Suicide, Suicide Attempt
Expanding Access to Evidence-Based Suicide Risk Assessment and Intervention in a Crisis Stabilization Setting
The overarching goal of this project is to expand access to evidence-based suicide risk assessment, safety planning, and intervention among patients at elevated suicide risk by implementing Jaspr in a real-world psychiatric…
- Conditions
- Suicide, Suicide Attempt, Randomized Controlled Trial (RCT)
- Trial name
- NCT07864961
- Testing
- Jaspr
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Butler Hospital
Social Disconnection
Social Disconnection Study
The purpose of this research study is to examine the effect of social connectedness on the brain. Study procedures include one Magnetic Resonance Imaging (MRI) or functional Magnetic Resonance Imaging (fMRI) scan, one Positron…
- Trial name
- NCT06705348
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yale University
Suicidal, Suicide, Attempted
Improving Coping to Reduce Suicide Risk Following ED Discharge
The researchers hope to learn whether an electronic safety plan (ESP) and a supportive text messaging program are feasible and acceptable to adult patients with recent suicidal thoughts or behavior after emergency department (ED)…
- Conditions
- Suicidal, Suicide, Attempted, Suicidal Ideation
- Trial name
- NCT06614946
- Testing
- Electronic Safety Plan (ESP), Text support
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Michigan
Suicide, Suicide Attempt
Suicidal Ideation Framework: Grounded Theory Study, Catalonia
This doctoral project aims to develop a comprehensive theoretical model of the process through which the suicidal ideation framework is configured as a symbolic, narrative, and relational expression, adopting a multiperspective…
- Conditions
- Suicide, Suicide Attempt, Suicide Ideation, Suicide Risk
- Trial name
- SUIF-GT-CAT (NCT07284238)
- Testing
- In-Depth Qualitative Interview, Discussion Group
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Eating Disorders, Suicide Risk
Cognitive-Behavioral and Digital Therapy for Suicide Risk in Eating Disorders
The purpose of this study is to determine if adding a digital intervention to standard cognitive-behavioral therapy (CBT) is more effective in preventing suicide risk and reducing eating disorder symptoms.
- Trial name
- NCT07417826
- Testing
- Cognitive Behavioural Therapy (CBT), Cognitive Behavioural Therapy (CBT) + Digital Therapy (DT)
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Universitat Autonoma de Barcelona
Suicidal Ideation, Suicide Attempt
Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part A
This Study will comprehensively evaluate a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self Harm
- Trial name
- Jaspr-PartA (NCT06223867)
- Testing
- Jaspr App + JAH, ETAU
- Where
- United States
- Volunteers
- 670 people
- Sponsor
- University of Massachusetts, Worcester