Clinical trials: Suicide and Self-harm
Suicide, Chronic Pain
Suicide Prevention for Patients With Chronic Pain
Patients with chronic pain and moderate suicide risk (n=60) will be randomized to receive remote-PST or remote-supportive psychotherapy.
- Trial name
- NCT04490265
- Testing
- Problem-solving treatment, Supportive Psychotherapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Veterans BioMedical Research Institute
Depression
Risperidone and Suicidality in Major Depressive Disorder
The purpose of this trial is to investigate the efficacy of risperidone as an adjunct to an antidepressant treatment in the acute management of suicidality during an episode of major depressive disorder.
- Trial name
- NCT00167154
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Insomnia, Depression
A Brief Behavioral Sleep Intervention for Depression Among Military Veterans
This study investigates the impact of brief behavioral insomnia treatment on depressive symptoms among military veterans.
- Conditions
- Insomnia, Depression, Suicidal Ideation
- Trial name
- NCT01958541
- Testing
- Sleep Intervention I, Sleep Intervention II
- Where
- 2 sites in United States
- Volunteers
- 77 people
- Sponsor
- Stanford University
Bipolar Disorder, Depression
Brain Tissue Collection for Neuropathological Studies
The purpose of this study is to collect and study the brain tissue of deceased individuals to learn more about the nervous system and mental disorders.
- Conditions
- Bipolar Disorder, Depression, Anxiety Disorders, Schizophrenia
- Trial name
- NCT00001260
- Where
- 3 sites in United States
- Volunteers
- 2,161 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Bipolar Disorder
Observation of Clozapine Treatment Safety in Bipolar Disorder.
The purpose of the registry is to record incidence of adverse events during treatment with clozapine in patients suffering from bipolar disorder.
- Trial name
- CloGD (NCT06011460)
- Testing
- Clozapine
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Gdansk
Bipolar Disorder, Suicidal Ideation
Effects of Lithium on Suicide Prevention in Adolescents and Young Adults With Bipolar Disorder in China
This study aims to use a retrospective cohort approach to explore the impact of lithium carbonate on suicide and self-harm related events among adolescents and young adults with bipolar disorder in China.The primary objective of…
- Conditions
- Bipolar Disorder, Suicidal Ideation, Suicide, Attempted, Nonsuicidal Self Injury
- Trial name
- NCT06424613
- Testing
- Lithium Carbonate, Non-lithium medication
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking University
Bipolar Depression, Suicidal Ideas
Sequential Therapy for the Treatment of Severe Bipolar Depression.
NeuroRx is developing NRX-101, a fixed-dose combination oral capsule composed of d-cycloserine (DCS) and lurasidone for the maintenance of remission from Severe Bipolar Depression with Acute Suicidal Ideation (C-SSRS level 4 or…
- Conditions
- Bipolar Depression, Suicidal Ideas, Suicidal Ideation, Suicide, Attempted
- Trial name
- STABIL-B (NCT02974010)
- Testing
- NRX-101 Oral Capsule, Lurasidone Oral Capsule, Ketamine Intravenous Infusion
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- NeuroRx, Inc.
Depressive Disorder
Study to Evaluate the Safety and Efficacy of PEER Interactive Versus Treatment as Usual in Subjects With a Primary Diagnosis of Depression
This is a prospective, multicenter, randomized, double-blind, controlled study to evaluate the effectiveness of PEER Interactive to inform treatment in subjects with a primary diagnosis of depression with comorbidity of…
- Trial name
- NCT01794559
- Testing
- PEER Interactive Report
- Where
- 2 sites in United States
- Volunteers
- 1,922 people
- Sponsor
- MYnd Analytics
Suicidal Ideation
Improving Screening and Follow Up for Suicidal Ideation and Behaviors Among Latinx Youth in Primary Care
The objective of this proposal is to develop and pilot a systems-level strategy in pediatric primary care to enhance identification and management of suicidal ideation and behavior in Latinx youth, particularly those in immigrant…
- Trial name
- NCT06229223
- Testing
- PALOMA
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Suicide, Attempted, Addiction
Suicide Attempts and Tramadol : a Case Report
In France, over the last years the use weak opioid analgesics decreased́, whereas that of strong opioid analgesics (OFMA). Hospitalizations for opioid overdose increased́ by 128% from 2000 to 2015, and deaths related to…
- Trial name
- NCT05075291
- Where
- France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Montpellier
Suicide Prevention
Suicide Prevention Study of VA-BIC in the Veteran Population
The VA is committed to reducing suicide in the U.S. Veteran population. Over 6,000 Veterans die from suicide each year, and this risk is particularly high following a psychiatric hospitalization.
- Trial name
- VA-BIC RCT (NCT04446468)
- Testing
- PEACE, Standard Psychiatric Hospital Discharge Care
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- VA Office of Research and Development
Suicide Attempt
Preventing Suicide With Digital Phenotyping and Pharmacogenetics-Based Interventions
The goal of this protocol for an observational retrospective multi-site cohort study is to develop a predictive algorithm for suicidal behavior integrating genetic risk markers, digital phenotypes, and exposomic data in people…
- Trial name
- SMARTomicS-R (NCT07422090)
- Testing
- No Intervention: Observational Cohort
- Where
- Spain
- Volunteers
- 5,000 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Bereavement, Depressive Disorder
Consequences of Conjugal Bereavement in Adults
Bereavement refers to the expected reactions and sadness associated with the loss of a loved one. It has been reported that the loss of a spouse is rated as the major life stressor among survivors of varying ages and diverse…
- Conditions
- Bereavement, Depressive Disorder, Immunologic Disease, Mental Disorder
- Trial name
- NCT00001659
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Suicidal Ideation
Compassion Meditation and ReliefLink App for Suicidal, Low-Income, African Americans
The purpose of this study is to conduct a pilot randomized controlled trial (RCT) with low-income, suicidal African American women and men that compares the relative effectiveness of compassion meditation (CM) versus a support…
- Trial name
- NCT03463980
- Testing
- Compassion meditation (CM), Support group (SG)
- Where
- United States
- Volunteers
- 456 people
- Sponsor
- Emory University
Suicidal Ideation, Suicidal Behavior
Brief Crisis Therapy for Suicidal Children and Adolescents
The goal of this clinical trial is to learn if the Ultra-Brief Interpersonal Psychotherapy for Adolescents with Suicidal Ideation (IPT-A-SCI) works to reduce suicidal thoughts and behaviors in children and adolescents.
- Trial name
- IPT-A-SCI (NCT07627243)
- Testing
- IPT-A-SCI
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Tel Aviv University
Suicide, Attempted
Clinical and Actigraphic Profile of Young Patients Admitted for Attempted Suicide
An excess suicide-related morbidity is observed among young people in the Picardie region, as reflected by the > 100% occupation rate of the Amiens University Hospital Adolescent Medicine Unit
- Trial name
- ACTIHUMEUR (NCT02803632)
- Testing
- questionnaires, actigraphic recording
- Where
- 2 sites in France
- Volunteers
- 98 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Major Depressive Episode (MDE), Major Depressive Disorder (MDD)
LHC-CIDI-5 in Hong Kong
The World Health Organization Composite International Diagnostic Interview-5th (CIDI-5) is a standardized diagnostic tool used to assess the prevalence of mental and substance use disorders over varying time frames (30 days, 12…
- Conditions
- Major Depressive Episode (MDE), Major Depressive Disorder (MDD), Persistent Depressive Disorder (PDD), Suicidal Ideation
- Trial name
- NCT06804525
- Testing
- CIDI-5, LHC-CIDI-5
- Where
- Hong Kong
- Volunteers
- 2,500 people
- Sponsor
- The University of Hong Kong
Suicide Prevention, Suicide
Integrating the Youth Nominated Support Team (YST) With CBT for Black Youth With Acute Suicide Risk: Aim 2b
This is a second pilot study being completed based on lessons learned from the Aim 2a feasibility pilot study (NCT06941311). Following modifications, the investigators are testing the acceptability, feasibility, and preliminary…
- Conditions
- Suicide Prevention, Suicide, Self-Injurious Behavior, Behavioral Symptoms
- Trial name
- NCT07506460
- Testing
- Cognitive Behavioral Therapy for Suicide Prevention (CBT-SP), Youth-Nominated Support Team
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Michigan
Substance Misuse, Suicide
A Digital Game Targeting Suicide Prevention in Adolescents Who Report Substance Misuse
The primary aim of this study is to design and develop a digital game that models the process of a safety planning intervention.
- Trial name
- NCT05517382
- Testing
- supportED, Control
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Yale University
Suicide Attempts, Suicidal Ideation
Advancing Suicide Intervention Strategies for Teens During High Risk Periods
To inform the effective management of adolescent suicide risk by evaluating promising treatments and developing the evidence-base for interventions that are well suited for widespread adoption, sustained quality, and impact.
- Conditions
- Suicide Attempts, Suicidal Ideation, Suicide and Self-harm, Suicide Threat
- Trial name
- ASSIST (NCT05078970)
- Testing
- Safety Planning Intervention+ (SPI+), Collaborative Assessment and Management of Suicidality (CAMS), Treatment As Usual
- Where
- 2 sites in United States
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital