Clinical trials: Suicide and Self-harm
Sleep Initiation and Maintenance Disorders, Depression
Improving Sleep and Psychological Functioning in People With Depression and Insomnia
This study will evaluate the safety and effectiveness of treatment with both a sleeping pill and antidepressant medication in improving sleep and psychological functioning in people with depression and insomnia.
- Trial name
- NCT00247624
- Testing
- Eszopiclone, Fluoxetine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Wake Forest University Health Sciences
Suicidal Thoughts and Behaviors
Developing and Testing a Brief, Personalized Intervention for Suicidal Thoughts and Behaviors
Suicide is a leading cause of death in the United States and around the world. Individuals at high-risk for suicide are heterogenous.
- Trial name
- AFSP_PRECISE (NCT07749391)
- Testing
- PRECISE
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of California, San Diego
Suicidal Ideation, Suicide Attempt
Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part A
This Study will comprehensively evaluate a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self Harm
- Trial name
- Jaspr-PartA (NCT06223867)
- Testing
- Jaspr App + JAH, ETAU
- Where
- United States
- Volunteers
- 670 people
- Sponsor
- University of Massachusetts, Worcester
Depression, Cancer Patients and Depression and Suicide
Improvement of Depression in Terminal Cancer Patients
This study investigates the potential of the water extract of Gastrodia elata Blume (WGE) to alleviate depressive symptoms in terminal cancer patients.
- Conditions
- Depression, Cancer Patients and Depression and Suicide, Life Quality
- Trial name
- IDTCP (NCT06785623)
- Testing
- Gastrodia elata Blume water extract
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Suicidal Ideation
Compassion Meditation and ReliefLink App for Suicidal, Low-Income, African Americans
The purpose of this study is to conduct a pilot randomized controlled trial (RCT) with low-income, suicidal African American women and men that compares the relative effectiveness of compassion meditation (CM) versus a support…
- Trial name
- NCT03463980
- Testing
- Compassion meditation (CM), Support group (SG)
- Where
- United States
- Volunteers
- 456 people
- Sponsor
- Emory University
Suicide, Suicide Prevention
Focused Suicide Prevention Strategy for Youth Presenting to the Emergency Department With Suicide Related Behaviour
Suicide is the leading cause of death due to illness among Canadian youth, claiming more lives than any medical illness, including cancer. Suicide prevention is possible, and early intervention is needed.
- Conditions
- Suicide, Suicide Prevention, Suicidal Ideation, Self-Injurious Behavior
- Trial name
- IAMSAFE (NCT06225661)
- Testing
- SAFE Intervention, NAV (Telephone Navigation)
- Where
- 4 sites in Canada
- Volunteers
- 330 people
- Sponsor
- The Hospital for Sick Children
Suicide Threat, Burnout, Professional
Modified Interactive Screening Program Plus MINDBODYSTRONG: A Mental Health Resiliency Intervention for Nurses
The overall purpose of this study is to evaluate the efficacy of an intervention designed to prevent nurse suicide. This randomized controlled trial will test the modified Interactive Screening Program (mISP) alone and the mISP…
- Conditions
- Suicide Threat, Burnout, Professional, Depression
- Trial name
- NCT05582343
- Testing
- MINDBODYSTRONG™
- Where
- United States
- Volunteers
- 849 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Non-Suicidal Self Injury, Suicide
Dialectical Behavioral Therapy in Juvenile Justice
Self-injurious thoughts and behaviors (SITBs) are a serious public health concern, particularly for youth involved in the juvenile justice system (JJS), which the Georgia State Juvenile Justice System (GAJJS) intends to address…
- Conditions
- Non-Suicidal Self Injury, Suicide, Self-harm, Emotion Regulation
- Trial name
- DBT-A&JJS (NCT05583279)
- Testing
- Dialetical Behavioral Therapy for Adolescents
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Catholic University of America
Suicidal Ideation, Depression Disorders
Acceptability and Feasibility of Reframe-IT+U for Suicidality in University Students.
Mental health in university students is a growing concern worldwide. In Chile, previous studies have shown high rates of depressive symptoms, anxiety, and suicidal risk in this population.
- Conditions
- Suicidal Ideation, Depression Disorders, Anxiety
- Trial name
- Reframe-IT+U (NCT07001202)
- Testing
- Indicated Prevention for suicidality
- Where
- Chile
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Brain Cancer, Breast Cancer
Study of Health Effects of Cosmetic Breast Augmentation
This study will examine long-term health effects of cosmetic breast augmentation (enlargement) with silicone gel breast implants.
- Conditions
- Brain Cancer, Breast Cancer, Lung Cancer, Suicide
- Trial name
- NCT00342953
- Where
- United States
- Volunteers
- 17,424 people
- Sponsor
- National Cancer Institute (NCI)
Major Depressive Disorder, Suicidal Ideation
MicroRNA Correlates of Childhood Maltreatment and Suicidality
This is a research study to find out if childhood trauma and stress are associated with depression or suicidal risk. The study will assess the effects of both short-term and long-term stress on biomarker (e.g.
- Trial name
- NCT04923685
- Testing
- Trier Social Stress Test
- Where
- 2 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Suicidal Ideation, Self Injurious Behavior Without Suicidal Intent
Experiences of Brief Admission From the Perspective of Family and Significant Others
As a result of a randomized controlled trial (NCT02985047) BA is continuously offered to persons with self-harm at risk for suicide in Skåne, Sweden.
- Conditions
- Suicidal Ideation, Self Injurious Behavior Without Suicidal Intent, Self-Harm, Deliberate
- Trial name
- NCT04962217
- Testing
- Semi-structured interviews
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- Region Skane
Suicide Attempt, Suicidal Ideation
Bae: A Smartphone Application for a Better Following Adolescents at Risk of Suicidal Behavior: Study of Acceptability and Preliminary Results of Efficacy
Suicidal behavior among adolescents is a major public health problem. Exacerbation of suicidal risk most often occurs when the young person is in his or her natural environment, far from the health care system.
- Trial name
- BAE (NCT04686162)
- Testing
- bae application
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Suicidal Ideation, Suicide, Attempted
A Pilot Study of Collaborative Assessment and Management of Suicidality With Suicidal Children ("CAMS-4Kids")
The purpose of the study is to assess the feasibility and acceptability of CAMS-4Kids for children with suicidal ideation and/or behavior.
- Trial name
- CAMS-4Kids (NCT04119648)
- Testing
- CAMS-4Kids
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Nationwide Children's Hospital
Alcohol Use Disorder (AUD), Suicidal Ideation
Examining the Relationship Between Ongoing Alcohol Use, Suicidal Thoughts and Behaviors and Related Constructs, and Behavioral Economic Decision-Making.
This study will evaluate the relationship between alcohol use, suicidal thoughts and behaviors, and behavioral economic decision-making.
- Trial name
- NCT07842588
- Testing
- CBT4CBT
- Volunteers
- 180 people
- Sponsor
- Mark J Rzeszutek, PhD
Suicide, Mental Health Disorder
Optimizing a Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents
Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death amongst youth. Digital tools, especially personal smartphones, are promising avenues to address these issues and can be…
- Conditions
- Suicide, Mental Health Disorder, Anhedonia
- Trial name
- NCT06665620
- Testing
- ViraBrite nudges
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Ksana Health
Suicide, Attempted
Socio-Educational Intervention for Rural Suicide Attempters
Compared to a treatment-as-usual group, providing brief mental health education to suicide attempters from rural parts of China at the time of their treatment in the emergency departments of general hospitals or local clinics and…
- Trial name
- NCT00808873
- Testing
- socio-educational intervention
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Beijing HuiLongGuan Hospital
Self-Injurious Behavior, Suicidal Ideation
Therapeutic Evaluative Conditioning to Reduce Adolescents' Self-injurious Thoughts and Behaviors During and After Psychiatric Inpatient Hospitalization
Suicide is the 2nd leading cause of death among adolescents, with the highest risk period for suicide being the month following psychiatric inpatient hospitalization.
- Conditions
- Self-Injurious Behavior, Suicidal Ideation, Suicide Attempts
- Trial name
- TEC (NCT05796531)
- Testing
- Therapeutic Evaluative Conditioning, Neutral comparison condition
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- Franciscan Hospital For Children, INC.
Psychological Distress, Suicidal Ideation
Development and Testing of imHere4U: A Digital Suicide Prevention Intervention for Cyberbullied Adolescents
The objective of this study is to test the feasibility and preliminary efficacy of Flourish (formerly referred to as imHere4U), a digital suicide prevention intervention for cyberbullied adolescents.
- Trial name
- NCT06002191
- Testing
- Flourish, Questionnaires of Online Experiences
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Pittsburgh
Bereavement, Depressive Disorder
Consequences of Conjugal Bereavement in Adults
Bereavement refers to the expected reactions and sadness associated with the loss of a loved one. It has been reported that the loss of a spouse is rated as the major life stressor among survivors of varying ages and diverse…
- Conditions
- Bereavement, Depressive Disorder, Immunologic Disease, Mental Disorder
- Trial name
- NCT00001659
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)