Clinical trials: Suicide and Self-harm
Suicide, Emergencies
Assisting in Decisions in Emergency Departments: (ED-AID) Study
This study will test a patient decision aid about safe firearm storage during suicidal crisis. The investigators hypothesize that participants with higher quality decisions after the decision aid will be more likely to change…
- Trial name
- ED-AID (NCT03478501)
- Testing
- Decision Aid
- Where
- 3 sites in United States
- Volunteers
- 49 people
- Sponsor
- University of Colorado, Denver
Suicide, Attempted, Suicidal Ideation
WellPATH-PREVENT: A Mobile Intervention for Middle-Aged and Older Adults Hospitalized for Suicidal Ideation or Attempt
The goal of this project is to test whether WellPATH-PREVENT (a novel, mobile psychosocial intervention) improves a specific aspect of emotion regulation, i.e., cognitive reappraisal ability, and reduces suicide risk in…
- Conditions
- Suicide, Attempted, Suicidal Ideation, Depression
- Trial name
- NCT05183230
- Testing
- WellPATH-PREVENT, Optimized WellPATH-PREVENT
- Where
- 2 sites in United States
- Volunteers
- 115 people
- Sponsor
- Weill Medical College of Cornell University
Suicidal Ideation, Suicide Risk
A Text-Based Expressive Writing Program for Adolescents at Risk of Suicide
The goal of this clinical trial is to learn if a structured expressive writing program can help reduce suicidal thoughts in adolescents and young adults who have experienced suicidal thoughts, suicide attempts, or self-harm.
- Conditions
- Suicidal Ideation, Suicide Risk, Self-Injurious Behavior, Adolescent Mental Health
- Trial name
- WRITE-SAFE (NCT07479823)
- Testing
- Structured Expressive Writing Intervention, Treatment as Usual (TAU)
- Volunteers
- 160 people
- Sponsor
- Hallym University Medical Center
Suicidal Ideation, Mental Health
Gamified Virtual Reality Exercise for Suicidal Ideation in Older Adults
This is a two-arm, parallel-group randomized controlled trial designed to evaluate the effectiveness of a gamified virtual reality (VR)-based exercise program in reducing suicidal ideation among community-dwelling older adults…
- Conditions
- Suicidal Ideation, Mental Health, Depression, Geriatric Psychiatry
- Trial name
- VR-GAME-SI (NCT07862803)
- Testing
- Gamified VR-Based Exercise Program, Conventional Exercise Program
- Where
- Iran
- Volunteers
- 200 people
- Sponsor
- Islamic Azad University, Sanandaj
Hereditary Angioedema (HAE), Suicidal Ideation
Suicide Ideation in Hereditary Angioedema
This study focuses on patients with Hereditary Angioedema (HAE) to better understand how mental health affects overall well-being.
- Conditions
- Hereditary Angioedema (HAE), Suicidal Ideation, Cardiovascular Risk
- Trial name
- HAE-SAFE (NCT06811467)
- Volunteers
- 100 people
- Sponsor
- Ivan Cherrez Ojeda
Suicide
Emergency Department Safety Assessment and Follow-up Evaluation (ED-SAFE)
The NIMH s RFA-Suicide Prevention in Emergency Medicine Departments recognizes the emergency department (ED) as an important setting to increase suicide detection and prevention efforts but observes that evidence-based practice…
- Trial name
- ED-SAFE (NCT01150994)
- Testing
- Safety Assessment and Follow-up Telephone Intervention (SAFTI).
- Where
- 8 sites in United States
- Volunteers
- 1,440 people
- Sponsor
- University of Massachusetts, Worcester
Nightmare
Cognitive-Behavioral Therapy for Children With Nightmares as a Mediator of Suicide Risk (COMAA)
Youth suicide risk has increased 56% in the last decade, and suicide is the leading cause of preventable death in children and adolescents.
- Trial name
- COMAA (NCT05588739)
- Testing
- Cognitive Behavioral Therapy
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- University of Oklahoma
Borderline Personality Disorder, Suicide
Efficacy of Dialectical Behavior Therapy Versus CAMS-informed Supportive Psychotherapy on Self Harming Behavior
Purpose: The purpose of this study is to investigate the efficacy of Dialectical Behavior Therapy (DBT) versus CAMS (Collaborative Assessment and Management of Suicidality) -informed supportive psychotherapy on the risk of…
- Trial name
- DiaS (NCT01512602)
- Testing
- DBT, CAMS
- Where
- Denmark
- Volunteers
- 108 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Suicide, Suicide Prevention
Comparing Suicide Prevention Interventions to Guide Follow-up Care: The SPRING Trial
Pragmatic randomized controlled trial to compare the effectiveness of two-way Caring Contacts text messages vs. one-way Caring Contacts text messages vs. enhanced usual care for suicide prevention in adults and adolescents.
- Conditions
- Suicide, Suicide Prevention, Suicide and Self-harm
- Trial name
- SPRING (NCT06128239)
- Testing
- Caring Contacts
- Where
- United States
- Volunteers
- 854 people
- Sponsor
- St. Luke's Health System, Boise, Idaho
Suicide, Aggression
Social Ecology and the Prevention of Suicide and Aggression in African American Youth
The purpose of this study is to examine the efficacy of a culturally-grounded, school-based suicide and aggression preventive intervention for African American adolescents (Adapted-Coping with Stress Course [A-CWS]).
- Trial name
- NCT03954457
- Testing
- A-CWS, Standard Care Control
- Where
- United States
- Volunteers
- 939 people, healthy volunteers welcome
- Sponsor
- DePaul University
Suicide Prevention
Suicide Prevention Study of VA-BIC in the Veteran Population
The VA is committed to reducing suicide in the U.S. Veteran population. Over 6,000 Veterans die from suicide each year, and this risk is particularly high following a psychiatric hospitalization.
- Trial name
- VA-BIC RCT (NCT04446468)
- Testing
- PEACE, Standard Psychiatric Hospital Discharge Care
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- VA Office of Research and Development
Personality Disorder, Borderline
Effectiveness of the Iconic Therapy for Borderline Personality Disorder Symptoms
Borderline personality disorder (BPD) is the most prevalent personality disorder in young community population whose most severe complication is suicide.
- Trial name
- NCT03011190
- Testing
- Emotional regulation
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Silvia Elisa Hurtado Santiago
Suicide
Combined TMS and Brief Cognitive Behavioral Therapy to Reduce Suicide
High rates of Veteran suicide remain a tragedy. Rates of Veteran suicide have not decreased for 10 years, despite the best efforts of the field.
- Trial name
- NCT03952468
- Testing
- Transcranial Magnetic Stimulation, Brief Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- VA Office of Research and Development
Suicide, Suicidal Ideation
TMS for Suicidal Crisis in Active Duty SMs
The purpose of this study is to determine if the use of Transcranial Magnetic Stimulation (TMS) provides rapid reduction and sustained attenuation of suicidal crisis.
- Conditions
- Suicide, Suicidal Ideation, Suicidal Impulses, Suicidal Intention
- Trial name
- TMS4SI (NCT03014362)
- Testing
- Neuronetics NeuroStar XPLOR magnetic stimulator - Active
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Eisenhower Army Medical Center
Suicide, Attempted, Suicide, Ideation
Teen Brain Training (TBT)
A non invasive treatment study including participants at risk for suicide attempts and undergoing neurofeedback training. Neurofeedback is controlling your brain activity in real time inside the scanner.
- Conditions
- Suicide, Attempted, Suicide, Ideation, Depression
- Trial name
- NCT06183580
- Testing
- neurofeedback training involving dACC, neurofeedback training involving amygdala
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Suicide Attempt, Depression
Effects of a Multifaceted School-Based Intervention to Protect Mental Health and Prevent Suicidal Behaviour in Adolescents in Spain
What is this study about? This study aims to find out if a school-based program can help improve mental health and prevent suicidal thoughts and behaviors in teenagers in Spain.
- Conditions
- Suicide Attempt, Depression, Adolescent Mental Health, Self-Harm
- Trial name
- NCT06996054
- Testing
- Multifaceted School-Based Mental Health and Suicide Prevention Program
- Volunteers
- 2,280 people, healthy volunteers welcome
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Suicidal Ideation, Suicide, Attempted
Randomized Clinical Trial of Re-Evaluating Suicidal Thoughts in Veterans
Suicide prevention is a top priority for VA as all continue to seek new and inventive ways to reduce suicide rates among Veterans.
- Trial name
- REST-V (NCT05884476)
- Testing
- Treatment-as-usual, Re-Evaluating Suicidal Thoughts
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- VA Office of Research and Development
Chronic Pain
Distress in Adolescents With Chronic Pain: Who is at Risk, When, and Why
Living with chronic pain can be tough for any young person. But while some young people may experience distressing thoughts, others may not. No young person should face these problems alone.
- Trial name
- NCT06619171
- Where
- 2 sites in United Kingdom
- Volunteers
- 70 people
- Sponsor
- University of Oxford
Interpersonal Trauma, Depression
The BEAR Program for Women With Trauma Who Have Suicidal Thoughts
The current study aims to test the feasibility of a new form of group therapy for women who have a history of interpersonal trauma and current suicidal ideation.
- Conditions
- Interpersonal Trauma, Depression, PTSD, Anxiety
- Trial name
- BEAR-SI (NCT07346638)
- Testing
- BEAR-SI
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stanford University
Suicidal Ideation, Attempted Suicide
A Randomized Trial for Suicidal Patients
Although suicide risk is highly prevalent among the patient population in mental health care, remarkably little research exists on effective treatments. Among a small set of novel approaches, CAMS is particularly promising.
- Conditions
- Suicidal Ideation, Attempted Suicide, Suicide
- Trial name
- NCT02685943
- Testing
- Psychotherapy
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Vestre Viken Hospital Trust