Clinical trials: Suicide and Self-harm
Suicide
CAMS-RAS: for Suicide Prevention
This Phase I feasibility study endeavors to create a prototype of a tool to determine its feasibility with suicidal patients in emergency departments (EDs). This is not a clinical trial.
- Trial name
- CAMS-RAS (NCT03072875)
- Testing
- CAMS-RAS
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Evidence-Based Practice Institute, Seattle, WA
Suicide
Suicide Risk Interventions
The suicide rate among active duty service members and Veterans increased substantially following the onset of post-9/11 conflicts in Iraq and Afghanistan.
- Trial name
- NCT05931289
- Testing
- Enhanced Crisis Response Planning (ECRP), Brief Cognitive Behavioral Therapy for Suicide Prevention (BCBT)
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- VA Office of Research and Development
Suicide and Self-harm
Suicide Prevention for Criminal Legal Involved Managed Care Subscribers
The goal of this clinical trial is to test the effects of a suicide prevention intervention for individuals released from jail. The main question it aims to answer is: Does the use of Caring Contacts improve subscriber engagement…
- Trial name
- NCT05579600
- Testing
- Caring Contacts letters
- Where
- United States
- Volunteers
- 45,155 people
- Sponsor
- Butler Hospital
Alcohol Use Disorder (AUD), Suicidal Ideation
Examining the Relationship Between Ongoing Alcohol Use, Suicidal Thoughts and Behaviors and Related Constructs, and Behavioral Economic Decision-Making.
This study will evaluate the relationship between alcohol use, suicidal thoughts and behaviors, and behavioral economic decision-making.
- Trial name
- NCT07842588
- Testing
- CBT4CBT
- Volunteers
- 180 people
- Sponsor
- Mark J Rzeszutek, PhD
Suicide, COVID-19
Qualitative Study of Suicidal Recrudescence Among Adolescents in November 2021
A qualitative study, combining psychiatric and anthropological perspectives, focused on the lived experiences of patients who had recourse to HPNCL emergencies during the period of November 2021, as well as the experiences and…
- Trial name
- Suicide-Covid (NCT05795894)
- Testing
- STAI-Y, BDI scale, M.I.N.I.Kid
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fondation Lenval
Depression, Suicidal Ideation
Engaging Black Youth in Depression and Suicide Prevention Treatment Within Urban Schools
Completing evidence-based treatments for depression has been shown to be particularly problematic for Black adolescents. If Black adolescents' depression treatment needs are to be met, the engagement challenges and the factors…
- Trial name
- NCT03940508
- Testing
- Making Connections Intervention, IPT-A
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- New York University
Major Depressive Disorder
Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression
The study will consist of a 24-week-long trial examining outcomes in patients with Major Depressive Disorder and suicidal ideation who will receive intravenous (IV) ketamine and intranasal (IN) esketamine, compared to a large…
- Trial name
- NCT05450432
- Testing
- Ketamine, Esketamine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Suicide
Comprehensive Adaptive Multisite Prevention of University Student Suicide
Suicide is the 2nd leading cause of death among college students and suicidal ideation and suicide-related behaviors are a frequent presenting problem at college counseling centers (CCCs), which are overburdened.
- Trial name
- CAMPUS (NCT04707066)
- Testing
- Treatment As Usual (TAU), Collaborative Assessment and Management of Suicidality (CAMS) - Phase 1, Dialectical Behavior Therapy (DBT) - Phase 2
- Where
- 4 sites in United States
- Volunteers
- 253 people
- Sponsor
- Duke University
Suicidal Ideation and Behavior
Design and Feasibility of an SMS-based Safety Planning Intervention
This study is testing whether it is feasible to run a larger randomized controlled trial and whether an automated text messaging program is acceptable to young adults who have suicidal thoughts.
- Trial name
- NCT07365579
- Testing
- Text Messaging based Safety Planning Intervention, Facilitated Referral to Crisis Resources
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwestern University
Suicidal Ideation, Alcohol Drinking
Computerized DBT Skills Training for Suicidal and Heavy Episodic Drinkers
Alcohol use is considered to be a significant risk factor among those who die by suicide, especially among those who drink to regulate their emotions.
- Trial name
- NCT02932241
- Testing
- Computerized Dialectical Behavior Therapy Skills Training
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Washington
Suicide, Co-design
Development of a Digital Acceptance and Commitment Therapy Intervention for Suicide Prevention in Adults Through Co-design
Suicide is a major public health concern and there is a need for accessible and scalable interventions to support individuals experiencing suicidal thoughts.
- Conditions
- Suicide, Co-design, Suicide Prevention
- Trial name
- NCT07733596
- Testing
- Digital ACT Intervention
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Hong Kong Polytechnic University
Suicidal Intention
Suicidal Thought and Biological Markers
Thought Markers (Tm) and Biomarkers(Bm) to accurately predict the likelihood of a repeated suicide attempt.
- Trial name
- STM (NCT01992445)
- Where
- 3 sites in United States
- Volunteers
- 375 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Posttraumatic Stress Disorder, Depression
A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity
The overarching goal of this UH2-UH3 proposal is to work with the NIH Health Care Systems Research Collaboratory to develop and implement a large scale, cluster randomized pragmatic clinical trial demonstration project that…
- Conditions
- Posttraumatic Stress Disorder, Depression, Alcohol-Related Disorders, Suicidal Ideation
- Trial name
- TSOS6 (NCT02655354)
- Testing
- Motivational Interviewing, Cognitive Behavioral Therapy Elements, Care Management
- Where
- 24 sites in United States
- Volunteers
- 635 people
- Sponsor
- University of Washington
Post Traumatic Stress Disorder, Cannabis Use
Warrior CARE: Cannabis Behavioral Health
This study is a randomized, controlled clinical trial to examine the therapeutic potential of cannabinoids for treating veterans with PTSD and suicidal ideation.
- Conditions
- Post Traumatic Stress Disorder, Cannabis Use, Suicide, Veterans
- Trial name
- CBH (NCT06381180)
- Testing
- Tetrahydrocannabinol, Cannabidiol
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Wayne State University
Suicidal Ideation, Suicidal Ideation and Behaviors
Transformative Mixed Evaluation of a Suicide Attempt Recovery Intervention
This study aims to evaluate the impact of a brief clinical group intervention based on the recovery model aimed at adult repeat suicide attempters attending an outpatient unit belonging to a public hospital in the Maule region…
- Trial name
- NCT06686498
- Testing
- Illness Management and Recovery adapted to suicidal behavior (IMR-ACS)
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- Oriana Arellano Faúndez
Suicide, Adolescent Behavior
Using Information and Communication Technologies to Prevent Suicide in Chile
A cluster randomized controlled trial (RCT) of a program based on information and communication technologies (ICT) will be conducted to prevent suicide and strengthen mental health among secondary school students in Chile.
- Trial name
- NCT03514004
- Testing
- ICT-based intervention
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Chile
Applied Suicide Intervention Skills Training
The Safety and Effectiveness of Gatekeeper Training in First Nations Communities
Gatekeeper training is where people in the community are trained to recognize and identify those who are at risk for suicide and assist them in getting care. Gatekeeper training has been widely implemented around the world.
- Trial name
- NCT02118116
- Testing
- Applied Suicide Intervention Skills Training
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Manitoba
Vitiligo, Depressive Episode
Mental Health Associations With Vitiligo
This cohort study is a large population-based study in the UK to determine the risks of comorbid mental health conditions (including depression, anxiety and other potential psychological complications of vitiligo) in adults with…
- Conditions
- Vitiligo, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04953338
- Testing
- Exposure of mental health condtion of interest
- Where
- United Kingdom
- Volunteers
- 36,104 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Glioblastoma (GBM)
Mental Health and Suicidality in Glioblastoma Patients in Germany
The aim of the study is to use standardized questionnaires to systematically record influencing factors or predictors for suicidal behavior in glioblastoma patients, particularly with regard to existing depression and anxiety…
- Trial name
- SHINE-GLIO (NCT07409584)
- Testing
- Medical history, physical examination, completing questionnaires, data collection
- Where
- 6 sites in Germany
- Volunteers
- 180 people
- Sponsor
- University Hospital, Essen
Insomnia
Effectiveness of eCBT-I on Improving Mental Health in Chinese Youths With Insomnia
This study aims to conduct a randomized control trial to validate the treatment effect of e-based cognitive behavioral therapy for Insomnia (e-CBT-I) on insomnia disorder, and explore whether e-CBT-I could prevent depression and…
- Trial name
- NCT04069247
- Testing
- e-CBT-I, e-HE
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 708 people
- Sponsor
- Chinese University of Hong Kong