Clinical trials: Suicide and Self-harm
Sleep Disorders, PTSD
Efficacy of a Brief Nightmare Treatment for Veterans
The purpose of this study is to find out what effects Exposure, Rescripting, and Relaxation Therapy (ERRT) has on nightmares and associated problems in veterans.
- Conditions
- Sleep Disorders, PTSD, Suicide
- Trial name
- NCT01220401
- Testing
- exposure, relaxation, and rescription therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Tulsa
Suicide, Attempted
Effectiveness of a Case Management Algorithm: ALGOS After a Suicide Attempt
The suicidal behaviors are phenomena eminently multifactorial. It is thus always difficult to define univocal strategies of prevention of suicide repetition, during the emergency stay, i.e. almost in general population.
- Trial name
- ALGOS (NCT01123174)
- Testing
- ALGOS algorithm of case management
- Where
- 23 sites in France
- Volunteers
- 1,040 people
- Sponsor
- University Hospital, Lille
Depression, Insomnia
PracticeGround: Transforming Training and Delivery of Mental Health EBPs
The ultimate goal is to facilitate the delivery of empirically supported treatments (ESTs) for mental disorders and to improve client mental health outcomes.
- Conditions
- Depression, Insomnia, Suicide
- Trial name
- NCT02314624
- Testing
- Behavioral Activation for Depression, Cognitive Behavior Therapy for Insomnia, Collaborative Assessment and Management of Suicidality, Care-as-Usual Psychotherapy
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Evidence-Based Practice Institute, Seattle, WA
Physician-Assisted Suicide
Physician-assisted Dying in Mentally Ill Patients - Which Criteria Are Decisive?
Physician-assisted dying (PAD) is currently a highly controversial topic in medical ethics and public debates worldwide. It poses a moral conflict between the ethical principle of respect for patient autonomy and the ethical…
- Trial name
- NCT05492461
- Volunteers
- 20,000 people
- Sponsor
- Psychiatric Hospital of the University of Basel
Suicide, Health Care Seeking Behavior
Program to Promote Engagement in Care for the Prevention of Recidivism
In France, the number of emergency visits for suicide attempts is estimated at 220,000 per year. Suicide management aims to reduce suicide risk factors in order to improve the mental health of patients and prevent recurrences.
- Conditions
- Suicide, Health Care Seeking Behavior, Case Management
- Trial name
- PEPS (NCT04366466)
- Testing
- suicide attempt patient using PEPS Program
- Volunteers
- 138 people
- Sponsor
- Januel
Death, Assisted, Tissue and Organ Procurement
Experience of Relatives and Intensive Care Units Caregivers of Controlled Donation After Circulatory Death
Controlled donation after circulatory death (cDCD) refers to organ donation (OD) from patients whose death is defined using circulatory criteria and from whom circulatory death occurs after a planned withdrawal of life-sustaining…
- Conditions
- Death, Assisted, Tissue and Organ Procurement, Life Support Care
- Trial name
- CARE-M3 (NCT05041023)
- Testing
- Relative section, Caregiver section
- Where
- France
- Volunteers
- 367 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Suicidal Ideation, Suicide Attempt
Expansion and Reevaluation of the Implicit Association Test in Suicide Ideators and Suicide Attempters
A new approach to investigate suicidal processes belongs to the broader neurocognitive picture and are so-called implicit associations.
- Trial name
- IAT-S (NCT04585802)
- Where
- Switzerland
- Volunteers
- 447 people
- Sponsor
- University of Bern
Depressive Disorder, Major, Suicidal
A Study of SLS-002 (Intranasal Racemic Ketamine) in Adults With Major Depressive Disorder at Imminent Risk of Suicide
The purpose of the study is to evaluate the efficacy, safety, and tolerability of SLS-002 (intranasal racemic ketamine) in addition to standard of care on symptoms of Major Depressive Disorder (MDD) and suicidality, in…
- Trial name
- NCT04669665
- Testing
- SLS-002, Standard of care, Intranasal device
- Where
- 21 sites in United States
- Volunteers
- 164 people
- Sponsor
- Seelos Therapeutics, Inc.
Social Isolation, Suicidal Ideation
Social Prescribing and Relationship Cognitive Strategies (SPARCS)
The study team is testing the acceptability and feasibility of two treatments for improving loneliness: Social Prescribing and Brief Cognitive Therapy.
- Trial name
- NCT06656975
- Testing
- Brief Cognitive Therapy, Social Prescribing, Enhanced Usual Care
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Self-Injurious Behavior, Suicidal Ideation
Therapeutic Evaluative Conditioning to Reduce Adolescents' Self-injurious Thoughts and Behaviors During and After Psychiatric Inpatient Hospitalization
Suicide is the 2nd leading cause of death among adolescents, with the highest risk period for suicide being the month following psychiatric inpatient hospitalization.
- Conditions
- Self-Injurious Behavior, Suicidal Ideation, Suicide Attempts
- Trial name
- TEC (NCT05796531)
- Testing
- Therapeutic Evaluative Conditioning, Neutral comparison condition
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- Franciscan Hospital For Children, INC.
Post-traumatic Stress Disorder, Traumatic Brain Injury
Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop
In this proposal, the investigators extend their previous SPiRE feasibility and preliminary effectiveness study to examine STEP-Home efficacy in a RCT design.
- Conditions
- Post-traumatic Stress Disorder, Traumatic Brain Injury, Substance Related Disorders, Depression
- Trial name
- STEP-Home (NCT03868930)
- Testing
- STEP-Home, PCGT
- Where
- 2 sites in United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Suicide
Ketamine for Acute Suicidal Ideation in the Emergency Department: Randomized Controlled Trial
This study will enroll patients presenting to the emergency department with acute suicidal ideation meeting inclusion and exclusion criteria.
- Trial name
- LDK-SI (NCT01892995)
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Suicide, Suicide, Attempted
Improving Firearm Storage in Alaska Native Villages
Rates of suicide among young Alaska Native males are over ten-fold higher than among a similar age cohort in the rest of the United States. A high proportion of these deaths are associated with firearms.
- Conditions
- Suicide, Suicide, Attempted, Wounds and Injuries
- Trial name
- NCT00643812
- Testing
- Installation of gun locker in household
- Where
- United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- University of Washington
Suicide, Trauma, Psychological
Wakȟáŋyeža (Little Holy One)
The overall goal of this study is to develop, adapt and evaluate an intergenerational prevention intervention, named "Wakȟáŋyeža (Little Holy One)," with Native American caregivers on a Northern Plains reservation and the…
- Conditions
- Suicide, Trauma, Psychological, Parenting
- Trial name
- NCT04201184
- Testing
- Newly created cultural components, adapted Family Spirit lessons, adapted CETA modules, Active nutrition control
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Suicide Prevention
Syncing Screening and Services for Suicide Prevention Across Health and Jail Systems
This study aims to harmonize jail release record data with electronic health record data in order to connect patients to an evidence-based suicide prevention and clinical care pathway upon jail release.
- Trial name
- NCT06506344
- Testing
- 5S Trial
- Where
- 2 sites in United States
- Volunteers
- 5,250 people
- Sponsor
- Henry Ford Health System
Insomnia
A Single-Session Online Insomnia Intervention
Cognitive-Behavioral Therapy for Insomnia (CBT-I) is a promising suicide intervention for college students because insomnia is robust risk factor for suicide ideation and CBT-I reduces suicide ideation.
- Trial name
- SSIT (NCT04988464)
- Testing
- Sleep Scholar, Building Healthy Habits
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Auburn University
Prolonged Grief Disorder, Suicidality
Prolonged Grief and Suicide Among Veterans
The primary research question in this study will ask, among those receiving outpatient mental health services (MHS) at the Eastern Colorado Healthcare System (ECHCS)/Denver Veterans Affairs Medical Center (VAMC), how many suffer…
- Trial name
- NCT01247025
- Testing
- No intervention
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Suicide
Suicide Re Attempts in Young Adults After First Suicide Attempt : Socio-demographic, Clinical and Biological Correlates
Suicide is the second leading cause of death among people aged 15 to 24 (WHO, 2014). After a first suicide attempt, the 18 to 25 years old would be very likely to repeat the act: 25 to 31% would make a new attempt in the…
- Trial name
- SURAYA (NCT03538197)
- Testing
- clinical and biological correlates
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Hôpital le Vinatier
Self Harm, Suicidal Ideation
Leverage Noninvasive Transcutaneous Vagus Nerve Stimulation to Reduce Suicidal Behaviors in Vulnerable Adolescents
Suicidal thoughts, suicide attempts, and suicide are increasingly common in adolescence. Current face-to-face prevention approaches are of limited effectiveness, rely on extensive resources, and are at odds with adolescents'…
- Trial name
- NCT05602779
- Testing
- tVNS Program, Phone App Program, tVNS and Phone App Program
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Notre Dame
Binge Drinking, Suicidal Ideation
Open Pilot Trial Evaluating an Avatar-Guided Intervention for Emerging Adults With Alcohol Use Problems and Suicide Risk
This study is an open pilot usability trial to test the 1) usability of a newly developed mobile health intervention to help manage suicidal ideation and alcohol use problems and 2) feasibility of research protocols with emerging…
- Trial name
- EA-Avatar (NCT06595862)
- Testing
- EA-Avatar
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Massachusetts, Worcester