Clinical trials: Supplement
Locally Advanced Head and Neck Carcinoma
Pea Protein Oral Nutrition Supplement for the Reduction of Gastrostomy Tube Placement Rate in Patients With Locally Advanced Head and Neck Cancer Undergoing Chemoradiation Therapy
This phase II trial studies the effect of a plant-based oral nutrition supplement, Kate Farms Standard 1.4 and/or Standard 1.0. as a primary source of nutrition in reducing the gastrostomy tube placement rate in patients with…
- Trial name
- NCT05115760
- Testing
- Dietary Supplement, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Prostate Adenocarcinoma, PSA Failure
White Button Mushroom Sup for the Reduction of PSA in Pts With Biochemically Rec or Therapy Naive Fav Risk Prostate CA
This phase II trial studies how well white button mushroom supplement works in reducing prostate-specific antigen (PSA) levels in patients with prostate cancer that has come back (recurrent) or has favorable risk and has not…
- Conditions
- Prostate Adenocarcinoma, PSA Failure, PSA Progression, Recurrent Prostate Carcinoma
- Trial name
- NCT04519879
- Testing
- Clinical Observation, Patient Observation, Questionnaire Administration
- Where
- 7 sites in United States
- Volunteers
- 133 people
- Sponsor
- City of Hope Medical Center
Nutraceuticals
The Effects of an Acute Dose of a Betalain-rich Concentrate on Repeated-sprint Cycling Performance and Recovery.
Betalains have well-known antioxidant and anti-inflammatory properties. Recent investigations examining the effects of a betalain-rich concentrate (BRC) on exercise and recovery performance show promise of BRC as an ergogenic…
- Trial name
- BET_RSE (NCT06274385)
- Testing
- Betalain-rich concentrate (AltRed)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Drexel University
Transplant Bone Disease
Pamidronate, Vitamin D, and Calcium for the Bone Disease of Kidney and Heart Transplantation
Bone is lost rapidly and fractures occur in 10-20% of patients who receive organ transplants within 2 years. The purpose of this study is to evaluate long-term effects of a pamidronate-vitamin D-calcium regimen on bone loss…
- Trial name
- NCT00302627
- Testing
- Pamidronate, vitamin D, Calcium Carbonate
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Providence Health & Services
Overweight and Obesity
Efficacy of Hydroxycinnamates and Beta-glucans as a Dietary Tool Against obesity_Pilot Study (OBHEALTH_PS)
Randomized, double blind, parallel study to assess the effect of a dietary supplement combining polyphenols (hydroxycinnamates from green coffee) and a soluble dietary fiber (oat beta-glucans) in obese/overweight subjects.
- Trial name
- OBHEALTH_PS (NCT04321590)
- Testing
- Combination of oat beta-glucan of different richness (35 and 70%) at low (3g) and high (5g) doses with green coffee bean extract (600 mg)
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Instituto de Ciencia y Tecnología de Alimentos y Nutrición
COVID-19
Randomized Proof-of-Concept Trial to Evaluate the Safety and Explore the Effectiveness of Resveratrol, a Plant Polyphenol, for COVID-19
Resveratrol is a plant polyphenol (that is sold commercially as a supplement) that might help fight coronavirus as well as help protect the body from the effects of disease (COVID-19) caused by the infection.
- Trial name
- NCT04400890
- Testing
- Resveratrol, Vitamin D3
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Marvin McCreary, MD
Apnea
Ventilation Using a Bag Valve Mask With Supplemental External Handle
Investigators compared tidal volumes for single rescuer ventilation using a modified bag valve mask with a supplemental external handle versus a conventional bag valve mask in a manikin model.
- Trial name
- NCT02800213
- Testing
- Modified Ambu Spur II bag valve mask, Conventional Ambu Spur II bag valve mask
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Growth Disorders, Dietary Exposure
Evaluating the Effects of an Oral Protein Supplement on Children's Growth Patterns
This single-center, randomized controlled pilot study aims to evaluate the efficacy of TruHeight Growth Protein Shake on improving growth patterns in children aged 4-17 years.
- Conditions
- Growth Disorders, Dietary Exposure, Child Development, Bone Development Abnormal
- Trial name
- NCT06329388
- Testing
- TruHeight Growth Protein Shake
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- TruHeight Vitamins
Periodontal Attachment Loss, Periodontal Pocket
Dietary Intakes and Periodontal Health: A Follow-Up Study
A previous study, on which this study is based, found that a diet higher in fruits and vegetables, beta-carotene, vitamin C, alpha-tocopherol, and fish oils (specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid…
- Trial name
- NCT03073174
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- Brock University
HIV Infections, Hypertriglyceridemia
The Effect of Fish Oil Plus Fenofibrate on Triglyceride Levels in People Taking Highly Active Antiretroviral Therapy (HAART)
The purpose of this study is to determine the effectiveness of fish oil supplements combined with the drug fenofibrate in treating elevated triglyceride levels in people taking anti-HIV drugs.
- Trial name
- NCT00076518
- Testing
- Fenofibrate, Fish Oil
- Where
- 5 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Effect of Food Supplement
Effect of Insect-derived Protein Supplements on Protein Synthesis and mTORC1 Activation
The purpose of this study is to determine the ability of insect-derived protein supplements (IPC80 and Whole Buffalo Powder Ynsect®) to activate the mTORC1 pathway and protein synthesis in muscle cells.
- Trial name
- NCT05457218
- Testing
- Whey protein, IPC80, Whole Buffalo Powder
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Protein Malnutrition
Formative Research Study to Address Protein Intake in Children and Analysis of Breast Milk Nutrient Content in Mothers
This formative research seeks to explore the use of egg (as a potential source of protein) as nutritional supplement for young children aged 6-8 months of either sex and breast milk composition of mothers of infants under 6…
- Trial name
- NCT03140696
- Testing
- Egg Alone, Egg and ready to use supplementary food (RUSF), Egg and breast milk
- Where
- Bangladesh
- Volunteers
- 30 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Glucose Intolerance
Effects of a Dietary Supplement Containing Salacia Extract, Citrus Bioflavonoids, and Trivalent Chromium on Markers of Glucose Control
This study was a double-blind, randomized, placebo-controlled, clinical trial with two parallel groups. Participants reported to a single investigational center in Ohio (i.e., The Center for Applied Health Sciences) during the 12…
- Trial name
- NCT05887050
- Testing
- Active
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- The Center for Applied Health Sciences, LLC
Diabetes Mellitus, Type 2, Cardiovascular Diseases
Zinc Supplementation Improves Cardiovascular Morbidity in Patients With Diabetes Mellitus
Oral zinc supplementation in patients with diabetes mellitus can improve glycemic control. However, there is reluctance to recommend zinc supplements to these patients because there is no evidence that the zinc-dependent…
- Trial name
- NCT05000762
- Testing
- Zinc
- Where
- United States
- Sponsor
- Wayne State University
Heart Failure
A Danish Pragmatic Randomized Trial of Nutritional Supplements in Heart Failure
Heart failure is a common and serious condition. Despite rapid advancements in heart failure treatment, the prognosis remains severe.
- Trial name
- DANUTRIO-HF (NCT06694727)
- Testing
- Coenzyme Q10 100 Milligrams Oral Capsule, Selenium 100 Micrograms Oral Tablets
- Where
- Denmark
- Volunteers
- 4,044 people
- Sponsor
- Tor Biering-Sørensen
Depression
Examination of a Soy-Based Supplement for Major Depression
The purpose of this study is to find out if the soy-based dietary supplement Novasoy (Registered Trademark) is effective for the short-term treatment of clinical depression.
- Trial name
- NCT00042380
- Testing
- Novasoy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Institute of Mental Health (NIMH)
Fatigue, Inflammation
Clinical Trial of the Seaweed Supplement Fucoidan in Survivors of Cancer
To determine the feasibility of an 8-week fucoidan supplement intervention for patients with fatigue post-cancer treatment and assess changes in fatigue, frailty, and inflammation.
- Trial name
- NCT06295588
- Testing
- Fucoidan extracted from F. Vesiculosus, Fucoidan extracted from U. Pinnatifida
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Rochester
Lactation
Efficacy and Safety of Milk Secretory Supplement in Breast-feeding Volunteers
The objective of this study are to evaluate efficacy and safety of milk secretory supplement containing fenugreek, banana flower, and ginger extract in breast-feeding volunteers
- Trial name
- NCT05880589
- Testing
- Milk secretory supplement group
- Where
- Thailand
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Cognitive Impairment, Dementia
COcoa Supplement and Multivitamin Outcomes Study for the Mind
The parent trial (COcoa Supplement and Multivitamin Outcomes Study, COSMOS; NCT02422745) is a randomized clinical trial of cocoa extract supplement (containing a total of 500 mg/d flavanols, including 80 mg.
- Conditions
- Cognitive Impairment, Dementia, Aging
- Trial name
- COSMOS-Mind (NCT03035201)
- Where
- United States
- Volunteers
- 2,262 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Hypertension
Post-marketing Study to Supplement Data on Safety, Tolerability and Efficacy of Micardis® With Special Emphasis on the Control of Blood Pressure
This post-marketing surveillance study is designed to supplement under conditions of normal clinical practice data on safety, tolerability and efficacy of Micardis® collected in clinical studies with special emphasis on the…
- Trial name
- NCT02242331
- Testing
- Micardis®
- Volunteers
- 19,805 people
- Sponsor
- Boehringer Ingelheim