Clinical trials: Supplementation
Very Low Birth Weight Infant, Nutritional Deficiency
Enteral Zinc Supplementation in Very Low Birth Weight Infants
The goal of this clinical trial is to observe for changes in rate of weight gain in the very low birth weight (VLBW) infants by adding an enteral Zinc supplement of 1 mg/kg/day of elemental zinc.
- Trial name
- NCT06433674
- Testing
- Zinc Sulfate, Sterile Water
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Toxicity Due to Radiotherapy
Supplementation With Dietary Anthocyanins and Side Effects of Radiotherapy for Breast Cancer
Attention has been focused recently on the development of modalities that can protect healthy organs from the harmful effects of radiation applied during different cancer treatment schedules.
- Trial name
- ATHENA (NCT02195960)
- Testing
- intake anthocyanin-rich corn extract
- Where
- Italy
- Volunteers
- 242 people
- Sponsor
- Neuromed IRCCS
Reticular Pseudodrusen (RPD), Age-Related Macular Degeneration
Vitamin A Palmitate Supplementation in Patients With Reticular Pseudodrusen (RPD) and Delayed Dark Adaptation
Background: Age-related macular degeneration (AMD) is an eye disease. It is the leading cause of vision loss in people over 55 in the U.S. Changes in the eye can make it difficult for they eye to adjust to low light.
- Trial name
- NCT03478878
- Testing
- Vitamin A Palmitate
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- National Eye Institute (NEI)
Pregnancy, High Risk
Use of Dietary Supplements in Patients at Risk of Abortion Treated With Progesterone.
The trial aims to investigate the effect of supplementation with hyaluronic acid, alpha-lipoic acid, magnesium, vitamin D and vitamin B6 in progesterone-treated pregnant women with risk factors for abortion.
- Trial name
- NCT04874285
- Testing
- HA
- Where
- Italy
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Lo.Li.Pharma s.r.l
Reflux Disease, Microbiome
Development of a Preparation for Supportive Supplementation of Probiotics in Patients With Reflux
A two-arm, double-blind, randomized, placebo-controlled study investigating the efficacy of a probiotic preparation developed as supportive supplementation of probiotics in patients with reflux.
- Conditions
- Reflux Disease, Microbiome, Probiotics Supplement
- Trial name
- NCT07600008
- Testing
- A probiotic dietary supplement
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- University Hospital Olomouc
Maternal Obesity, Obesity
The Developmental Origins of Obesity
Pregestational obesity (PGO, BMI ≥30) is a significant independent risk factor for the development of obesity in childhood and adolescence.
- Trial name
- OMEGA-Stem (NCT06981676)
- Testing
- DHA and EPA
- Where
- Chile
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Cutaneous Melanoma, Stage II, Malignant Cutaneous Melanoma
Evaluation of Oncoxin-Viusid® in Cutaneous Melanoma
Malignant melanoma, responsible for 75% of deaths from skin cancer. Current therapeutic options have poor response, many adverse events and high costs.
- Conditions
- Cutaneous Melanoma, Stage II, Malignant Cutaneous Melanoma, Cutaneous Melanoma, Stage III
- Trial name
- NCT03541148
- Testing
- Oncoxin-Viusid
- Where
- Cuba
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Catalysis SL
Caffeine
Caffeine and Training Intensity Quantification
The goal of this clinical trial is to learn about the effects of caffeine on exercise physiology and the subsequent quantification of athlete training zones in trained cyclists.
- Trial name
- NCT06210984
- Testing
- Low caffeine dose, Moderate caffeine dose
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Gastrointestinal Symptoms, Breath Test
Effect of Probiotic Supplementation on Lactose Maldigestion Induced by Fat-free Milk
The main objective of the study is to investigate the effect of probiotic supplementation on lactose maldigestion.
- Trial name
- NCT03659747
- Testing
- Probiotic, Lactrase
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- Danisco
Dry Eye Symptoms, Allergic Conjunctivitis of Both Eyes
Kelulut Honey for Allergic Conjunctivitis and Dry Eye Symptoms
The goal of this clinical trial is to learn if oral Kelulut honey works to improve eye symptoms in adults with allergic conjunctivitis. It will also look at how safe Kelulut honey is when taken as a daily supplement.
- Trial name
- NCT07273747
- Testing
- Kelulut Honey 60 g Oral Supplement, Kelulut Honey 120 g Oral Supplement
- Where
- Malaysia
- Volunteers
- 72 people
- Sponsor
- Universiti Sains Malaysia
Ketosis, Type 2 Diabetes
Exogenous Ketones in Type 2 Diabetes
Exogenous ketone supplements are proposed to have glucose-lowering potential, provide an alternative fuel for the brain and to enhance cognitive function.
- Trial name
- NCT04194450
- Testing
- Ketone monoester
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- University of British Columbia
Impaired Fasting Glucose, Pre Diabetes
Dietary Interventions in Prediabetes
Assessment of glucose metabolism and liver fat after 12 week dietary intervention in pre diabetes subjects. Subjects will be randomized to either high fat (olive oil supplemented),high carb/high fiber (beans supplemented) and…
- Conditions
- Impaired Fasting Glucose, Pre Diabetes, Liver Fat
- Trial name
- NCT01729078
- Testing
- Dietary intervention
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Mayo Clinic
Anemia of Chronic Kidney Disease
Effect of Adding Lactoferrin on Oral Iron on Anemia in Chronic Kidney Disease Patients
The aim of this study is to evaluate the effects of adding lactoferrin to the every-other-day oral iron supplementation in iron deficiency anemia and chronic kidney disease patients.
- Trial name
- NCT05900635
- Testing
- Lactoferrin, Ferrous Glycine Sulfate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Cancer, Breast Cancer
EXERT-BC Protein: Protein Supplementation to Improve Body Composition After Treatment for Breast Cancer
In this study, the investigators hypothesize that a high dose of post-workout protein after each exercise session will have greater improvements in changes in body composition, including muscle mass and percent body fat versus a…
- Trial name
- NCT07704476
- Testing
- Whey protein (60 grams), No protein
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Breast, Breast Cancer
A Study of High-Dose Vit D Versus Standard of Care Vit D Supplementation
This is a randomized study evaluating the effects of early intensive vitamin D supplementation compared to standard of care vitamin D supplementation on bone health over an 18 month period.
- Conditions
- Breast, Breast Cancer, Osteoporosis
- Trial name
- NCT05016310
- Testing
- High Dose Vitamin D, Standard of Care Vitamin D
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Wake Forest University Health Sciences
Sepsis, Septic Shock
Dose-response Study of Arginine Supplementation in Severe Sepsis
Pilot data in patients and data from pig studies indicate that arginine-NO metabolism is impaired in sepsis with changes in splanchnic metabolism and function, and reduced survival at low nitrate levels.
- Trial name
- NCT01775020
- Testing
- L-arginine
- Volunteers
- 8 people
- Sponsor
- Maastricht University Medical Center
Osteoporosis, Osteopenia, Osteoporosis, Postmenopausal
Effects of Vitamin D Supplementation in Muscle Strength and Balance Training
Introduction: In Brazil, a person who is sixty years old or more is considered elderly. The incidence of osteoporosis and osteopenia has been increasing, as have fractures resulting from falls.
- Trial name
- NCT03367585
- Testing
- Physical exercise + Vitamin D3, Physical exercise
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- University of Sao Paulo General Hospital
Hyperlipidemia
Effect Of Capros Supplementation On Cardiovascular Disease Risk Factors In Humans
The hypothesis of this study is that the natural supplement Capros will decrease LDL levels, platelet aggregation, and serum concentrations of high sensitivity C-reactive protein in humans at risk for cardiovascular disease.
- Trial name
- Capros (NCT01858376)
- Testing
- Capros dietary supplement
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Chandan K Sen
Malnourished Children, Stunting of Growth
Comprehensive Nutritional Support for Children in Zambia (ZamCNC) - A Pilot Investigation
In a recently completed intervention study, more than 50% of children in Lusaka were found to be stunted by age two, even when nutritional supplements were provided.
- Trial name
- ZamCnC (NCT07153913)
- Testing
- Intensive growth support
- Where
- Zambia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Günther Fink
Aging
The Efficacy of Oral Mitoquinone (MitoQ) Supplementation for Improving Physiological in Middle-aged and Older Adults
The purpose of this study is to assess the efficacy of supplementation with the mitochondria-targeted antioxidant, mitoquinone (MitoQ), for improving physiological function (vascular, motor, and cognitive) in middle-aged and…
- Trial name
- NCT02597023
- Testing
- MitoQ
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder