Clinical trials: Supplements
One-carbon Metabolism in Healthy Individuals
Impact of High-dose Folic Acid Supplementation on Pathways Linked to DNA Formation
Periconceptional supplementation with folic acid - the synthetic form of the B-vitamin folate - reduces the occurrence of adverse pregnancy outcomes such as spina bifida.
- Trial name
- NCT01687127
- Testing
- Folic acid, 5-methyltetrahydrofolate, calcium salt
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Prostate Cancer
Vitamin D and Soy Supplements in Treating Patients With Recurrent Prostate Cancer
RATIONALE: Vitamin D and soy extract may be effective in lowering prostate-specific antigen (PSA) levels in patients with recurrent prostate cancer that has not responded to previous treatment.
- Trial name
- NCT00499408
- Testing
- Vitamin D, soy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Wake Forest University Health Sciences
Myelodysplastic Syndrome
The Effect of Combination Ultra Q10 and L-carnitine on the Course of Myelodysplastic Syndrome
The purpose of this study is determine whether combination Q10 , L-carnitine and multivitamin and mineral complex is effective in treatment of patients with low and intermidiate1-2 risk Myelodysplastic syndrome
- Trial name
- NCT02042482
- Testing
- Coenzyme Q10U, L-carnitine
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Kaplan Medical Center
Changes in Gut Microbiota with Prebiotic Supplementation, Quality of Life
Effect of a Nutritional Supplement on Gut Microbiota in Adults
According to International Scientific Association for Probiotics and Prebiotics (ISAPP), a prebiotic is defined as a substrate that is selectively utilized by host microorganisms conferring a health benefit (Gibson et al, 2017).
- Trial name
- NCT06611215
- Testing
- Treatment
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Pharmavite LLC
Dietary Supplements, Healthy
Nitrate Supplementation on Motor Unit Activity
This study aimed to assess if nitrate supplementation influence motor unit (MU) activity following a sustained ischemic contraction and whether this is affected by blood flow restriction (BFR) during the recovery period.
- Trial name
- NCT05993715
- Testing
- Nitrate supplementation
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Metabolic Syndrome
Marin Protein Hydrolysate and Metabolic Syndrome
Overweight and obesity are increasing global health problems and the most important contributors to morbidity and mortality. The maintenance of long-term weight loss is difficult, and individuals often regain weight after an…
- Trial name
- MPH_MetS (NCT03807752)
- Testing
- MPH_active
- Where
- 2 sites in Norway
- Volunteers
- 33 people
- Sponsor
- Helse Møre og Romsdal HF
Skeletal Muscle Growth
Muscle Growth Following a Resistance Training Program in Men and Women Consuming Protein Supplements
Soy and whey protein have different concentrations of leucine, an amino acid known to be a particularly potent simulator of muscle protein synthesis.
- Trial name
- NCT03868631
- Testing
- Whey protein supplement, Soy protein supplement
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Point Loma Nazarene University
Athletic Performance
Study on How Pre-Workout Supplements Affect Shooting Accuracy in Trained Basketball Players
Basketball is a popular team sport where athletes score points by successfully shooting the ball into the basket. Accuracy in shooting is crucial for players to score points effectively.
- Trial name
- NCT06995209
- Testing
- Pre-workout Supplement
- Where
- Greece
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- International Hellenic University
Obesity
Use of Herbal Supplements in Weight Loss and Weight Maintenance
Effects of herbal products on weight loss, weight maintenance and metabolic rate. The objective of this study is to evaluate the efficacy of two herbal weight loss products, BioLean and BioLean Free compared to each other and a…
- Trial name
- NCT00198809
- Testing
- Biolean + Diet education, Biolean Free + Diet education
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Pre-Eclampsia, Hypertension, Pregnancy-Induced
Low Dose Calcium to Prevent Preeclampsia
The purpose of this study is to assess, in pregnant women with calcium-poor diets, what is the effectiveness of low-dose (500 mg/day) calcium supplements associated with an educational intervention, compared to the educational…
- Conditions
- Pre-Eclampsia, Hypertension, Pregnancy-Induced, Dietary Calcium Deficiency
- Trial name
- AMCAL (NCT02338687)
- Testing
- calcium, Educational sessions
- Where
- Brazil
- Volunteers
- 1,040 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Dry Eye Syndromes
Treatment of Dry Eye With Supplements
Dry eye syndrome (DES) is a highly prevalent ocular condition inducing an inflammatory response on the ocular surface. Common symptoms include ocular discomfort, visual impairment and instability of the tear film with potential…
- Trial name
- NCT01364311
- Testing
- Vitamac® Tag and Nacht capsules
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Depression
Combination Therapy of Different Antidepressants With Dietary Supplements
The aim of this clinical trial is to compare the effect of antidepressants in combination with different dietary supplements in patients with depression.
- Trial name
- NCT05931965
- Testing
- L-methylfolate, Vitamin B12, magnesium
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- Riphah International University
Skeletal Muscle
Leucine or Protein Supplementation and Resistance Training
The purpose of this study was to determine the effects of L-leucine (LEU) or different protein supplements standardized to LEU (~3.0 g/serving) on changes in body composition, strength, and histological attributes in skeletal…
- Trial name
- MPS (NCT03501628)
- Testing
- L-leucine + maltodextrin, Whey protein concentrate, Hydrolyzed whey protein concentrate
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Auburn University
Major Depression, Cancer
Omega 3 FA Supplements as Augmentation in the Treatment of Depression
To assess the efficacy of Omega 3 Fatty acid (Omega 3 FA) augmentation of desvenlafaxine (DVS) compared to placebo augmentation of DVS when used to treat depression and anxiety symptoms in patients with select medical conditions…
- Conditions
- Major Depression, Cancer, Diabetes, Cardiovascular Diseases
- Trial name
- NCT01803711
- Testing
- Desvenlafaxine, Omega 3 Fatty acids
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- UConn Health
Critical Illness, Dietary Modification
Probiotics in Enteral Feeding in Critically Ill Patients
The purpose of this study is to investigate the effect of probiotics in enteral nutrition on improving gut function, inflammatory markers and clinical outcomes in critically ill patients admitted to the intensive care unit.
- Conditions
- Critical Illness, Dietary Modification, Probiotics, Gut Failure
- Trial name
- NCT01792401
- Testing
- Probiotics
- Where
- Malaysia
- Volunteers
- 49 people
- Sponsor
- University of Malaya
Dyslipidemia, Lipid Metabolism
Advanced Strategy of Food Supplements for the Optimization of Satiety and Lipid Metabolism in Maturity (SACIANS)
The SACIANS study (Advanced Strategy of Food Supplements for the Optimization of Satiety and Lipid Metabolism in Middle-Aged Adults) aims to evaluate the combined effect of commercially available food supplements on satiety and…
- Conditions
- Dyslipidemia, Lipid Metabolism, Satiety Response, Overweight and/or Obesity
- Trial name
- SACIANS (NCT07269795)
- Testing
- Food Supplement Combination (SACIANS Formula)
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Insulin Resistance, Nutritional Disease
Effect of 6-week Strawberry Supplementation on Insulin Action (STR2)
The primary study objective is to investigate the potential chronic beneficial effect of polyphenolics derived from strawberry on impaired insulin signaling in insulin resistant individuals through their ability to modulate…
- Conditions
- Insulin Resistance, Nutritional Disease, Metabolic Disease
- Trial name
- NCT01457612
- Testing
- Strawberry
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Mental Health, Depression
Viome Nutritional Programs to Improve Clinical Outcomes for Mental Health Conditions
US residents who have mental health issues sign the informed consent form and are screened and enrolled for this study. Participants who are enrolled complete a survey upon enrollment and are randomized into one of three arms.
- Conditions
- Mental Health, Depression, Anxiety
- Trial name
- NCT05563857
- Testing
- VIOME Precision Nutrition Program, VIOME-designed condition-based supplements
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Viome
Premature, Feeding Disorders
Effect OF Lactase Enzyme Supplements ON Intolerance IN Preterm Neonates
This study aims to study the effect of lactase enzyme in preventing feeding intolerance in preterm neonates in neonatal intensive care unit at Alexandria University Children's Hospital.
- Conditions
- Premature, Feeding Disorders, Lactase Deficiency, Congenital
- Trial name
- NCT07088302
- Testing
- lactase administration
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Schistosomiasis, Liver Fibrosis
Antioxidant Supplements in the Reversal of Schistosomal Peri-portal Fibrosis
Liver fibrosis is the most serious complication of schistosomiasis mansoni. However only limited proportion of subjects with infection develop this pathology and there is limited knowledge on risk factors for the differential…
- Conditions
- Schistosomiasis, Liver Fibrosis, Periportal Fibrosis, Oxidative Stress
- Trial name
- NCT01260012
- Testing
- Praziquantel+antioxidant suppl, Praziquantel+antioxidant
- Where
- Ethiopia
- Volunteers
- 414 people
- Sponsor
- Addis Ababa University