Clinical trials: Supplements
Alzheimer Disease, Dementia
Development of NIC5-15 in the Treatment of Alzheimer's Disease
The purpose of this study is to evaluate the safety and efficacy of NIC5-15in the treatment of Alzheimer's Disease.
- Trial name
- NCT00470418
- Testing
- NIC5-15
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- VA Office of Research and Development
Depressive Disorder, Pregnancy
EnBrace HR for Depression Treatment and Prevention in Women Trying to Conceive and Early Pregnancy
The purpose of this study is to assess the effectiveness of the EnBrace HR prenatal supplement in preventing depression in women with a history of depression who have decided to stop taking antidepressants during their pregnancy…
- Trial name
- NCT02676882
- Testing
- EnBrace HR
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Sleep Disorders, Hypertension
Melatonin Supplements for Improving Sleep in Individuals With Hypertension
This study will evaluate the effectiveness of treatment with melatonin supplements in improving sleep in individuals with high blood pressure who are taking beta-blockers.
- Trial name
- NCT00238108
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Brigham and Women's Hospital
Prostate Cancer
Vitamin D and Soy Supplements in Treating Patients With Recurrent Prostate Cancer
RATIONALE: Vitamin D and soy extract may be effective in lowering prostate-specific antigen (PSA) levels in patients with recurrent prostate cancer that has not responded to previous treatment.
- Trial name
- NCT00499408
- Testing
- Vitamin D, soy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Wake Forest University Health Sciences
Skeletal Muscle Growth
Muscle Growth Following a Resistance Training Program in Men and Women Consuming Protein Supplements
Soy and whey protein have different concentrations of leucine, an amino acid known to be a particularly potent simulator of muscle protein synthesis.
- Trial name
- NCT03868631
- Testing
- Whey protein supplement, Soy protein supplement
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Point Loma Nazarene University
Major Depression, Cancer
Omega 3 FA Supplements as Augmentation in the Treatment of Depression
To assess the efficacy of Omega 3 Fatty acid (Omega 3 FA) augmentation of desvenlafaxine (DVS) compared to placebo augmentation of DVS when used to treat depression and anxiety symptoms in patients with select medical conditions…
- Conditions
- Major Depression, Cancer, Diabetes, Cardiovascular Diseases
- Trial name
- NCT01803711
- Testing
- Desvenlafaxine, Omega 3 Fatty acids
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- UConn Health
Stroke, Ischemic Stroke
Dietary Nitrate Supplements and Ischemic Stroke Recovery
This is a double-blind, randomized, placebo-controlled, pilot study. Participants will be randomized to receive either beetroot juice or a beetroot juice placebo, as a dietary supplement, for 30 days.
- Conditions
- Stroke, Ischemic Stroke, Cerebrovascular Accident
- Trial name
- NCT02838901
- Testing
- Beet it Beetroot juice
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Wake Forest University Health Sciences
HIV-associated Co-morbidities
Vitamin D Supplements for HIV-positive Patients on cART
The ability of vitamin D to modulate the immune system and strengthen bones may mitigate the adverse medication consequences of HIV/AIDS, but little is known about either the health benefits of vitamin D supplements, or about the…
- Trial name
- NCT01295034
- Testing
- conventional vitamin D treatment, tiered/titrated vitamin D dosing
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Andrea Branch
Healthy Volunteers
SPM Regulation by Fish Oil Supplements in Healthy Volunteers
A randomised, double-blind, placebo-controlled study to determine whether fish oil supplementation regulates peripheral levels of specialized pro-resolving mediators and white blood cell responses in healthy volunteers
- Trial name
- NCT03347006
- Testing
- SPM Active
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Dietary Supplements
A Study Evaluating Quality of Life Parameters Following Use of Emergen-C
The purpose of this study is to determine how Emergen-C use can improve quality of life (QoL) in a real-world setting to help consumers and healthcare professionals understand the benefits of taking Emergen-C on a routine or…
- Trial name
- NCT06654089
- Testing
- Emergen-C Core Super Orange Powder
- Where
- United States
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- HALEON
Myocardial Infarction, Iron-deficiency
An Open Study on the Efficacy of Iron Therapy Using iv Iron Relative to Oral Iron for Increasing LV Systolic Function
The OPERA-MI trial evaluates the effect of i.v. ferric carboxymaltose compared to the effect of oral iron, on left ventricular systolic function.
- Trial name
- OPERA-MI (NCT05309499)
- Testing
- ferric carboxymaltose, ferrous sulphate
- Where
- Russia
- Volunteers
- 298 people
- Sponsor
- Kazan State Medical University
Overweight
Oxidized Omega-3 Supplements With Different Oxidation
The oxidation level of unsaturated fatty acid supplements commercialized in capsules could be a serious problem for manufacturers and a risk to consumers; health by ingesting substances whose effects are not desired.
- Trial name
- GPTPASPAD (NCT01799720)
- Testing
- Less oxidized oil and diet, More oxidized oil and diet, Hypercholesterolemic diet
- Where
- Spain
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Colon Cancer, Rectal Cancer
Genistein in Treatment of Metastatic Colorectal Cancer
Colorectal neoplasms are the third most common malignancies in the United States. Patients with metastatic (stage IV) colorectal cancer have a median life expectancy of 2 years.
- Conditions
- Colon Cancer, Rectal Cancer, Colorectal Cancer
- Trial name
- NCT01985763
- Testing
- Genistein
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Sofya Pintova
Sexual Dysfunction, Sexuality and Reproductive Issues
L-Arginine Supplements in Treating Women Who Are Cancer Survivors
RATIONALE: L-arginine supplements may improve the quality of life and sexual function in women who are cancer survivors. PURPOSE: This randomized clinical trial is studying an L-arginine supplement to see how well it works…
- Conditions
- Sexual Dysfunction, Sexuality and Reproductive Issues, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00459134
- Testing
- ArginMax
- Where
- 25 sites in United States
- Volunteers
- 186 people
- Sponsor
- Wake Forest University Health Sciences
Non-Alcoholic Fatty Liver Disease
Fish Oil and Nonalcoholic Fatty Liver Disease (NAFLD) Study
Over the past 30 years, the prevalence of childhood obesity in the United States has tripled from 5% to 15%. Major consequences of obesity include insulin resistance, type- 2 diabetes, cardiovascular disease and nonalcoholic…
- Trial name
- NCT01285362
- Testing
- Fish Oil Supplementation
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Columbia University
Haematological Malignancy
Impact of Oral Nutritional Supplements on Patients Undergoing Haematopoietic Stem Cell Transplantation
Malnutrition is common after haematopoietic stem cell transplantation (HSCT), and is a well-known prognostic factor for survival.
- Trial name
- NCT05460013
- Testing
- Traditional Control, Oral Nutritional Supplement
- Where
- China
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Obesity, Diabetes Mellitus, Type 2
Supplements for Controlling Resistance to Insulin
The purpose of this study is to evaluate the effects of a combination of hydroxcycitrate (HCA) and niacin-bound chromium, in conjunction with nutrition education, over a twelve week period.
- Trial name
- SCORE (NCT00699413)
- Testing
- nutrition education plus active supplement, nutrition education plus inactive supplement
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Southern California
HIV
CCRC: A Project of the Treatment of HIV Enteropathy With ImmunoLin® Supplements
The purpose of the study is to see if ImmunoLin® will reduce the frequency of bowel movements and gastrointestinal (GI) symptoms in HIV volunteers with persistent GI symptoms.
- Trial name
- NCT01313910
- Testing
- Immunolin®
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, Davis
Pediatric Bipolar Spectrum Disorders
Inositol and Omega-3 Fatty Acids in Pediatric Mania
The purpose of this study is to a) evaluate the efficacy of omega-3 fatty acids versus inositol in the treatment of pediatric bipolar disorder, b) evaluate the efficacy of omega-3 fatty acid plus inositol in the treatment of…
- Trial name
- NCT01396486
- Testing
- Omega-3, Inositol
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Massachusetts General Hospital
Alcohol Use Disorder
Broccoli Extract Supplementation in Older Adults With Alcohol Use Disorder
Chronic alcohol consumption leads to perturbations in gut microbiome balance (dysbiosis) and disruption of gut barrier integrity.
- Trial name
- NCT05902754
- Testing
- Generally Recognized as Safe - Sulforaphane
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans