Clinical trials: Supportive Therapy
Trauma, Flail Chest
Operative Treatment of Unstable Thoracic Cage Injuries and Chest Wall Deformity in Trauma
The purpose of this prospective controlled study is to determine whether surgical management of unstable thoracic cage injuries and chest wall deformity in trauma reduces the need for and the time spent on ventilator compared to…
- Conditions
- Trauma, Flail Chest, Rib Fractures, Surgery
- Trial name
- NCT02132416
- Testing
- NSAID, Opioids, Thoracic Epidural anaesthesia
- Where
- 2 sites in Sweden
- Volunteers
- 92 people
- Sponsor
- Sahlgrenska University Hospital
Multiple Sclerosis
A RCT of Telephone-supported ACT in MS
This study will investigate the feasibility of running a randomised controlled trial (RCT) of a psychotherapy called "Acceptance and Commitment Therapy (ACT)", delivered in a self-help format with additional telephone support…
- Trial name
- NCT02596633
- Testing
- Telephone-support Acceptance and Commitment Therapy (ACT)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Autoimmune Diseases, Inflammation
Prospective Study of White Blood Cells
The purpose of this study is to investigate white blood cells from volunteering donors to support the development of engineered regulatory T cell therapies.
- Conditions
- Autoimmune Diseases, Inflammation, Rejection; Transplant, Liver
- Trial name
- NCT04838171
- Testing
- White blood cell and blood collection
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Quell Therapeutics Limited
Clinical Self-Efficacy, Psychological Outcomes
Supportive Care-Based Training and Psychological Outcomes in Midwifery Students
The aim of this study is to comparatively evaluate the effects of trauma-informed supportive care model training in childbirth and universal supportive care model training in childbirth provided to midwifery students on their…
- Conditions
- Clinical Self-Efficacy, Psychological Outcomes, Secondary Traumatic Stress
- Trial name
- NCT07322484
- Testing
- Universal Continuous Supportive Care Model Training, Trauma-Informed Supportive Care Model Training
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Mersin University
Liver Failure, Critical Care
Oxidative Stress and Microcirculation in Patient With Hepatic Failure Undergoing Liver Support Treatment
Background: In patients undergoing hemodialysis or hemofiltration will suffer from the injury of reactive oxidative species. Oxidative stress will affect cell membrane, protein, and DNA.
- Trial name
- NCT00772252
- Testing
- liver support treatment
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
Nasopharyngeal Carcinoma, Nutritional Support
Early and Whole Course Nutritional Support by Nutren® Optimum During IMRT for Nasopharyngeal Carcinoma
Radiation therapy remains the principal treatment for nasopharyngeal carcinoma (NPC). The most frequently occurred radiation-related side effect is probably the radiation-induced oral mucositis, which affects up to 100% of NPC…
- Trial name
- NCT03344068
- Testing
- Radiotherapy, Chemotherapy, Nutren® Optimum
- Where
- China
- Volunteers
- 408 people
- Sponsor
- Sun Yat-sen University
Medication Adherence
Personalized Routine and Habit Integration to Support Medication Management
The objective of this study is to test a multidisciplinary care team behavioral intervention to enhance medication adherence among older adults with multiple chronic conditions (MCC).
- Trial name
- PRISM (NCT07914452)
- Testing
- PRISM Arm, Enhanced Usual Care Arm
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Brigham and Women's Hospital
Medication Adherence
Final Prototype Refinement of Adaptive Cell Phone Support
The goal of this feasibility pilot trial is to finalize the design of a mobile health intervention for promoting medication adherence in a population of adolescents and young adults with chronic health conditions.
- Trial name
- ACPS (NCT07084155)
- Testing
- Adaptive Cell Phone Support
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Children's Hospital Los Angeles
Hypoxic-Ischemic Encephalopathy, Perinatal Asphyxia
EEG-Based Decision-Support Algorithm for Hypoxic-Ischemic Encephalopathy in Term Newborns
This retrospective, multicenter, observational study evaluates how well a decision-support algorithm can tell apart mild forms of hypoxic-ischemic encephalopathy (HIE) from moderate or severe forms in full-term newborns born…
- Conditions
- Hypoxic-Ischemic Encephalopathy, Perinatal Asphyxia, Neonatal Brain Injury
- Trial name
- COOLDECIDE (NCT07764315)
- Volunteers
- 310 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiogenic Shock, Extracorporeal Membrane Oxygenation Complication
Cangrelor on Top of anticoagUlation in Patients With myocaRdial Infarction-related Cardiogenic Shock/Cardiac Arrest receiVIng VA-ECMO
The SURVIVE trial aims to test whether using an anti-thrombotic regimen involving cangrelor can reduce bleeding risk while maintaining effective antithrombotic effects in patients on VA-ECMO due to cardiogenic shock (CS)/ cardiac…
- Conditions
- Cardiogenic Shock, Extracorporeal Membrane Oxygenation Complication, Platelet Dysfunction
- Trial name
- SURVIVE (NCT06792643)
- Testing
- Cangrelor
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS San Raffaele
Missing Teeth
Expectation and Satisfaction of Implant Rehab After Jaw Surgery
Objective: The aim of this prospective study was to investigate the patient-reported outcome measures (PROMs) of implant-supported prostheses (ISP) among patients who had excised pathological jaw lesions.
- Trial name
- NCT04873635
- Testing
- Implant support prostheses
- Volunteers
- 31 people
- Sponsor
- The University of Hong Kong
Advanced Neuroendocrine Tumors of Pancreatic Origin
Efficacy and Safety of Everolimus (RAD001) Compared to Placebo in Patients With Advanced Neuroendocrine Tumors
The purpose of this study was to evaluate progression free survival in those participants assigned everolimus 10 mg/day plus Best Supportive Care versus those assigned to placebo plus Best Supportive Care in Advanced…
- Trial name
- RADIANT-3 (NCT00510068)
- Testing
- Everolimus
- Where
- 82 sites in United States, Belgium and 16 more
- Volunteers
- 410 people
- Sponsor
- Novartis Pharmaceuticals
Homelessness, Health Behavior
Peer Support for Homelessness in the Emergency Department
Peer support workers with lived experience of homelessness will provide advocacy, supportive counselling, assistance with navigating the system, and role-modeling for people experiencing homelessness in emergency departments in…
- Conditions
- Homelessness, Health Behavior, Health Care Utilization, Health Care Seeking Behavior
- Trial name
- NCT04012697
- Testing
- Peer Support
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- McMaster University
Scoliosis Idiopathic Adolescent, Scoliosis Idiopathic Adolescent Treatment
Augmented Reality-Assisted Physiotherapy for Adolescents With Idiopathic Scoliosis: A Qualitative Study
This study aims to explore the effects of augmented reality (AR)-supported physiotherapy on body awareness, motivation, and exercise adherence in adolescents diagnosed with Adolescent Idiopathic Scoliosis (AIS).
- Trial name
- AR-AIS (NCT07067125)
- Testing
- AR-Supported Scoliosis-Specific Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Hasan Kalyoncu University
Labor Pain
The Effect of Continuous Midwifery Care at Birth on Labor Pain, Comfort and Satisfaction
Introduction: Birth is a period in which biological, physical, emotional and social changes are experienced. Supportive care provided by the midwife ensures the adaptation of the woman to labor and improves her ability to cope…
- Trial name
- NCT05520060
- Testing
- Physical support, Psychospiritual support, Environmental and sociocultural support
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Opioid Tapering
Prescription Opioid Discontinuation: Honoring Patient Insights and Experience to Support Safe and Caring Transitions -- Decision Aid Pilot
Because of recent policies to decrease opioid use, some people using long-term opioid therapy (LTOT) are encouraged or required to stop (discontinue) taking opioids.
- Trial name
- PHOENIX (NCT07202026)
- Testing
- Patient-centered Decision Aid to support long-term opioid therapy tapering
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kaiser Permanente
Parkinson Disease
A Reminder App for Supporting Adherence to Treatment Goals in Parkinson's Disease
Parkinson's Disease is a progressive condition which affects the nervous system causing tremors, slowed movement and often causes problems with memory and initiation.
- Trial name
- NCT05106985
- Testing
- ApplTree reminder app
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- NHS Greater Glasgow and Clyde
Nurse-led Supportive Care
Effects of Nurse-led Supportive Care Programme on Caregiver Burden and Resilience of Family Caregivers
Lung cancer is the leading cause of cancer-related deaths worldwide, with a mortality rate of 18%. The prognosis of lung cancer is progressive and devastating, which may cause patients to experience problems during the treatment…
- Trial name
- NCT06204289
- Testing
- Nurse-led Supportive Care Programme
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Izmir Bakircay University
Childhood Obesity, Disordered Eating
Disordered Eating Risk in Pediatric Obesity Treatment Using a Digi-Physical Tool
The goal of this observational study is to evaluate the risk of developing disordered eating behavior or an eating disorder among children and adolescents with obesity who have used a digi-physical treatment tool with daily…
- Conditions
- Childhood Obesity, Disordered Eating, Binge Eating Disorder, Anorexia Nervosa
- Trial name
- NCT06807489
- Testing
- Digi-physical treatment tool
- Where
- Sweden
- Volunteers
- 312 people
- Sponsor
- Karolinska Institutet
Gastric Cancer, Adenocarcinoma
Study of IMC-1121B (Ramucirumab) With Best Supportive Care in Participants With Gastric Cancer and Adenocarcinoma
The purpose of this study is to gather information about the use of an investigational drug called Ramucirumab in adenocarcinomas of the stomach or gastroesophageal junction.
- Trial name
- NCT00917384
- Testing
- ramucirumab, Best Supportive Care (BSC)
- Where
- 161 sites in United States, Argentina and 28 more
- Volunteers
- 355 people
- Sponsor
- Eli Lilly and Company
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