Clinical trials: Supportive Therapy
Breast Cancer
Evaluating a Digital Tool for Supporting Breast Cancer Patients
This is a prospective randomised controlled trial that aims to understand the impact of the OWise breast cancer digital tool in newly diagnosed breast cancer patients.
- Trial name
- ADAPT (NCT03866655)
- Testing
- OWise
- Where
- United Kingdom
- Volunteers
- 165 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Idiopathic Pulmonary Fibrosis, Pulmonary Fibrosis
Supporting Adherence to Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is an irreversible, chronic and relentless lung disorder of unknown aetiology leading ultimately to respiratory insufficiency and death within 2-5 years after diagnosis.
- Trial name
- SUPIRIO (NCT03567785)
- Where
- Belgium
- Volunteers
- 66 people
- Sponsor
- KU Leuven
Geriatric Oncology, Supportive Care
The GOS-Frail (Geriatric Oncology Supportive Care for Frail Older Adults With Cancer) Study
Background Cancer is more prevalent in older adults, but most cancer treatment trials have mainly involved young and healthy subjects.
- Conditions
- Geriatric Oncology, Supportive Care, Quality of Life
- Trial name
- GOS-Frail (NCT06553378)
- Testing
- Geriatric Oncology Supportive Clinic
- Where
- Singapore
- Volunteers
- 154 people
- Sponsor
- Tan Tock Seng Hospital
Smoking
Strategies to Avoid Returning to Smoking
The purpose of this study is to evaluate the relative efficacy of a postpartum smoking relapse prevention program, Strategies to Avoid Returning to Smoking (STARTS), and a supportive, nondirective comparison condition (SUPPORT)…
- Trial name
- STARTS (NCT00757068)
- Testing
- CBT addressing postpartum mood and weight concerns, Supportive Behavioral Therapy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Opioid Addiction
Integrating Support Persons Into Recovery
INtegrated Support Persons Into Recovery (INSPIRE) is a 4-year research project that tests whether integrating a patient's support person into a patient's treatment with Buprenorphine/Naloxone can improve outcomes.
- Trial name
- INSPIRE (NCT04239235)
- Testing
- CRAFT
- Where
- 6 sites in United States
- Volunteers
- 439 people, healthy volunteers welcome
- Sponsor
- Stanford University
Hormone Receptor Positive Breast Cancer
Telehealth Intervention for Symptom Management and Adherence to Adjuvant Endocrine Therapy
The goal of this study is to demonstrate the efficacy of an evidence-based, small-group, telehealth intervention ('STRIDE') for improving patients' ability to cope with side effects from adjuvant endocrine therapy (AET) and…
- Trial name
- STRIDE (NCT07759947)
- Testing
- STRIDE, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- Massachusetts General Hospital
Anorexia Nervosa
Effectiveness Trial of Temperament Based Therapy With Support (TBT-S)
The main aim of this project is to determine the short and long-term effectiveness of an out-patient treatment for patients with anorexia nervosa.
- Trial name
- NCT06497101
- Testing
- Temperament Based Therapy with Support (TBT-S)
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Obesity, Childhood
DAta-driven personaLIzation of a digitAl Health Solution to Support Family Caregivers of Children With Chronic Conditions
The goal of this feasibility study is to explore the needs of families with children with obesity and evaluate the impact of a combined intervention (children with obesity receiving pharmacological therapy in combination with the…
- Trial name
- DALIA (NCT06520787)
- Testing
- ACDP® and pharmacological treatment for obesity
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Adhera Health, Inc.
Leukemia, Childhood, Solid Tumor, Childhood
Observational MyPal-Child Study on the ePRO-based Early Palliative Care Digital System in Paediatric Oncology Patients
The main aim of the study is the evaluation of the feasibility of comprehensive service which has been developed while considering patient-orientated needs.
- Trial name
- MyPal4Kids (NCT04381221)
- Where
- 3 sites in Czechia, Germany
- Volunteers
- 100 people
- Sponsor
- Centre for Research and Technology Hellas
Testicular Cancer, Testis Cancer
Helping Young People With Testicular Cancer Using Virtual and Extended Reality
TRANSCEND-XR is a European research project designed to better support adolescents and young adults who have been cured of testicular cancer.
- Conditions
- Testicular Cancer, Testis Cancer, AYA Cancer Survivors, Survivor Patients
- Trial name
- TRANSCEND-XR (NCT07571499)
- Testing
- Digital tool using extended reality
- Volunteers
- 245 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Oral Mucositis, Quality of Life
Retrospective Observational Study of Oral Complications and Quality of Life in Head and Neck Cancer Patients Treated With Radiotherapy or Chemoradiotherapy.
Head and Neck cancer patients receiving radiation therapy (with or without chemotherapy) suffer several oral complications, such as oral mucositis, which impairs quality of life of patients during radiotherapy and in the…
- Conditions
- Oral Mucositis, Quality of Life, Mucositis, Pain
- Trial name
- NCT07739771
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Mucosa Innovations, S.L.
HIV Disease Progression
Acceptability, Feasibility and Effectiveness of Online Peer Support Group for ART Adherence Among Youth
In Uganda, Youth living with HIV/AIDS (YLHIVA) enrolled in HIV treatment experience suboptimal treatment adherence and have lower viral load suppression (VLS) rates compared to younger children or adults.
- Trial name
- NCT05688709
- Testing
- WhatsApp peer support group
- Where
- 3 sites in Uganda
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Infectious Diseases Research Collaboration, Uganda
Breast Cancer
Monoclonal Antibody Therapy, Cyclosporine, and Paclitaxel in Treating Patients With Recurrent or Refractory Metastatic Breast Cancer
RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells.
- Trial name
- NCT00009763
- Testing
- filgrastim, monoclonal antibody m170, cyclosporine
- Where
- United States
- Sponsor
- University of California, Davis
Hypertension, Treatment Adherence and Compliance
InTake Care: Development and Validation of an Innovative, Personalized Digital Health Solution for Medication Adherence Support in Cardiovascular Prevention
Inadequate medication adherence (MA) in chronic conditions, including cardiovascular prevention, represents an important risk factor.
- Conditions
- Hypertension, Treatment Adherence and Compliance, Digital Health
- Trial name
- InTakeCare (NCT06229171)
- Testing
- adherence support system based on a vocal assistant
- Where
- Italy
- Volunteers
- 206 people
- Sponsor
- Istituto Auxologico Italiano
Prematurity, Respiratory Disease
Caffeine as an Adjuvant Therapy for Late Preterm Infants With Respiratory Distress
Use of caffeine citrate in late-preterm infants with respiratory distress is questionable. Oliphant and colleagues found in a recently published study that caffeine therapy use in late-preterm infants at a loading dose of 20 and…
- Conditions
- Prematurity, Respiratory Disease, Ventilator Lung; Newborn
- Trial name
- CAT/LPT (NCT06026163)
- Testing
- Caffeine citrate
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 134 people
- Sponsor
- Ministry of Health, Saudi Arabia
Hearth Failure, Systolic
Blind Assessment of the Concordance Between the Administered Treatment and the Recommendations of a Medical Algorithm Decision Support Software in Systolic Heart Failure
The PREMEDIC is a prospective, observational study. Patients hospitalized for Systolic Heart Failure will be enrolled and health data will be collected at hospital admission and during hospital stay.
- Trial name
- PREMEDIC (NCT02900547)
- Testing
- Patients with systolic heart failure
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Central Hospital, Nancy, France
HIV, AIDS
Adherence Support Intervention for Persons Living With HIV/AIDS (PLWHA) on Antiretroviral Therapy (ART) in Estonia
The specific aim of the study is to assess antiretroviral therapy adherence and evaluate the impact of a situated treatment adherence intervention program among persons living with HIV/AIDS on antiretroviral therapy in Estonia.
- Conditions
- HIV, AIDS, Medication Adherence
- Trial name
- NCT01789138
- Testing
- Situated Optimal Adherence Intervention
- Where
- 2 sites in Estonia
- Volunteers
- 519 people
- Sponsor
- University of Tartu
Humeral Diaphysis Fracture
Conservative Treatment Versus the Surgical Treatment of Diaphyseal Fractures of Humerus
The fracture of the humeral diaphysis is a condition that represents 2% of all fractures. The conservative treatment of diaphyseal fractures of the humerus has long been considered the only option and the surgical treatment was…
- Trial name
- NCT01116349
- Testing
- Plate and screws or nailing, Hanging Support System (HSS) brace
- Where
- 2 sites in Canada
- Volunteers
- 4 people
- Sponsor
- Hopital de l'Enfant-Jesus
Short Bowel Syndrome
A Study of Teduglutide in Japanese Children With Short Bowel Syndrome Aged 4 Months or Older
The main aims of the study are to check for side effects from teduglutide. Participants will receive a daily injection of teduglutide just under the skin (subcutaneous) for 24 weeks. Then they are followed up for another 4 weeks.
- Trial name
- NCT05027308
- Testing
- Teduglutide
- Where
- 6 sites in Japan
- Volunteers
- 3 people
- Sponsor
- Takeda
Leukemia, Lymphoma
Pharmacokinetic Study of Palifermin in Subjects Receiving Radiation Therapy and Chemotherapy Followed by Blood Stem Cell Support
Open label palifermin will be administered to subjects who are at a risk of developing mucositis after radiotherapy and chemotherapy followed by blood stem cell support.
- Conditions
- Leukemia, Lymphoma, Myeloma
- Trial name
- NCT00070616
- Testing
- Palifermin 6 x 60 μg/kg/day, Palifermin 2 x 180 μg/kg/day, radiotherapy
- Volunteers
- 25 people
- Sponsor
- Swedish Orphan Biovitrum
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.