Clinical trials: Supportive Therapy
Breast Cancer, Breast Neoplasm
Vocational Rehabilitation for the Return to Work of Breast Cancer Patients: a Feasibility Study
In Italy, 50% of new breast cancer (BC) diagnosis occur in female of working age. Although return to work (RTW) is strongly desired by BC patients, cancer survivors are more likely to be unemployed than healthy individuals.
- Trial name
- VocRehab (NCT05309265)
- Testing
- Multidisciplinary vocational rehabilitation intervention
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Breast Cancer, Psychology, Social
Effectiveness of Screening and Brief Interventions for Alcohol and Tobacco During Breast Cancer Treatment (ONKODETOX)
Despite scientific, clinical and political incentives, alcohol and/or tobacco screening and brief intervention (SBI) services are poorly implemented in oncology settings.
- Trial name
- ONKODETOX (NCT03371732)
- Testing
- Motivational Intervention group, Educational advises group
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Institut Bergonié
Group Meetings
Feasibility of Therapy Integrating Peer-sharing, Technology, Aerobic and Resistance Training (TIPSTART)
The purpose of this randomized controlled clinical trial with first-generation college students with symptoms of mental illness is to test the preliminary feasibility and efficacy of TIPSTART, a multi-faceted, mental health and…
- Trial name
- TIPSTART (NCT04813198)
- Testing
- TIPSTART
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Sepsis, Critical Illness
Exploring and Establishment of Combined Extracorporeal Life Support(CELS) in Critically Ill Children
Multiple organ failure (MODS) is still the leading cause of death in children in ICU. The treatment of MODS is mainly organ function monitoring and organ replacement therapy.
- Conditions
- Sepsis, Critical Illness, MODS
- Trial name
- CELS (NCT03654287)
- Testing
- Treatment
- Where
- China
- Sponsor
- Guoping Lu
Tuberculosis
Clinical Decision-support Reminders to Improve IPT Initiation Among HIV Positive Adults in Western Kenya
The overall research objective is to evaluate the impact of implementing a reminder system for medical providers to improve TB case-finding and isoniazid preventative therapy (IPT) for adults living with HIV in western Kenya
- Trial name
- TBTech (NCT01934309)
- Testing
- TB reminders
- Where
- Kenya
- Volunteers
- 3,782 people
- Sponsor
- Indiana University
Myelodysplastic Syndromes
A Survival Study in Patients With High Risk Myelodysplastic Syndromes Comparing Azacitidine Versus Conventional Care
The purpose of this study is to determine whether patients with high-risk myelodysplastic syndromes (MDS) treated with azacitidine have improved survival compared to conventional care treatments.
- Trial name
- NCT00071799
- Testing
- Azacitidine, Physician Choice
- Where
- 108 sites in United States, Australia and 13 more
- Volunteers
- 358 people
- Sponsor
- Celgene
Frailty
Piloting Prehabilitation Before Abdominal Surgery
Frail Veterans are at increased risk for poor surgical outcomes, and as the Veteran population grows older and more frail, there is a critical need to identify effective strategies for reducing surgical risks for these patients.
- Trial name
- NCT03040336
- Testing
- Prehabilitation
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- VA Office of Research and Development
Health Education, First Aid
Readiness for Basic Life Support in Schools
This research is a response to problems with Cardiovascular Disease in Colombia, where circulatory system diseases are the first cause of mortality in the adult population, making them a critical issue for the country.
- Conditions
- Health Education, First Aid, Cardiopulmonary Resuscitation
- Trial name
- NCT04914871
- Testing
- Protocol UN Lifeguard Kids in the Tunja version, Educational session accident prevention and wound management
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Esophagus Injury, Rectal Lesion
Suprasorb® CNPendo Used for Negative Pressure Therapy in the Oesophagus and Rectum to Support Defect and Wound Healing
A Post-Market Clinical Follow-up (PMCF) study designed as non-interventional, observational, prospective, multicentre study in a routine clinical care setting using a marketed medical device in line with the corresponding…
- Trial name
- Velox (NCT05476263)
- Where
- 7 sites in Germany
- Volunteers
- 110 people
- Sponsor
- Lohmann & Rauscher
Language Development Disorders
The Effect of Semantic Support on Word Learning
The goal of this clinical trial is to compare word learning outcomes in late talking toddlers who are taught different types of words.
- Trial name
- NCT05921214
- Testing
- VAULT Phase 5
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Arizona
Lung Cancer
Connect Oncology Needs Evaluation Tool
The purpose of this research study is to evaluate a technology-based intervention, Caregiver Oncology Needs Evaluation Tool (CONNECT), which may increase lung cancer caregivers' knowledge about the benefits of supportive care…
- Trial name
- CONNECT-LC (NCT03919864)
- Testing
- CONNECT Intervention, CONTROL Group
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Wake Forest University Health Sciences
Conduct Disorders in Adolescence, Oppositional Defiant Disorder
Is Mentalization-based Therapy More Effective Than Treatment-as-usual for Adolescents With Dissocial Disorders?
The goal of this clinical trial is to investigate if Mentalization-based therapy (MBT) is superior to enhanced usual care (treatment-as-usual-plus (TAU-plus)) for adolescents with disruptive behavior or dissocial disorders.
- Trial name
- MEDAL (NCT07181928)
- Testing
- Mentalization-Based Therapy (MBT), Treatment-as-usual-plus (TAU-plus)
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- University Hospital Heidelberg
Survivorship, Breast Cancer
Accessible Cancer Care to Enable Support for Survivors Programme
In Singapore, cancer patients are not consistently assessed for unmet survivorship care needs and systematically identified for subsequent referral to useful care services.
- Conditions
- Survivorship, Breast Cancer, Gynecologic Cancer
- Trial name
- ACCESS (NCT04014309)
- Testing
- Supportive and survivorship care program, Usual care
- Where
- Singapore
- Volunteers
- 226 people
- Sponsor
- National University of Singapore
C. Difficile Enteritis
Support of Colonization Resistance of the Gut Microbiota with the Synbiotic Food Supplement Nagasin®
Double blind, placebo-controlled, parallel, multicentric trial to investigat whether Nagasin® can support the colonization resistance against C.difficile.
- Trial name
- NCT05800704
- Testing
- Nagasin, maltodextrin
- Where
- 6 sites in Switzerland
- Volunteers
- 49 people
- Sponsor
- University of Zurich
Very Preterm Infant, Very Low Birthweight
LIFT-UP: Randomized Controlled Trial of Fortification of Human Milk
The goal of the LIFT-UP randomized controlled trial is to evaluate the efficacy of feeding routinely and fortified human milk using a standardized clinical protocol to very low birthweight (VLBW) or very preterm (VPT) infants in…
- Trial name
- LIFT-UP RCT (NCT06765863)
- Testing
- Human Milk Fortifier, Volume targets
- Where
- 4 sites in India
- Volunteers
- 776 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Multiple Myeloma
Efficacy of Bortezomib Consolidation After High-dose Melphalan With Stem Cell Support in Myeloma Patients
Multiple myeloma is a malignant incurable hematological disease where survival has been significantly improved by high-dose melphalan with autologous stem cell support (ASCT) in younger patients.
- Trial name
- NCT00417911
- Testing
- bortezomib
- Where
- 20 sites in Denmark, Finland and 3 more
- Volunteers
- 400 people
- Sponsor
- Nordic Myeloma Study Group
Kidney Diseases, Cardiometabolic Risk Factors
Feasibility Trial of a Stakeholder-enhanced Lay-navigator-delivered Intervention (ImPart-Multi)
The purpose is to explore the feasibility and acceptability of participation in a decision-support training program led by lay navigators.
- Trial name
- ImPart-Multi (NCT06067009)
- Testing
- ImPart-Multi - IMproving the decisional PARTnership of Chronic Kidney Disease Dyads with concurrent metabolic disease
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Alabama at Birmingham
Chronic Spinal Cord Injury
LIFT Home Study of Non-Invasive ARC Therapy for Spinal Cord Injury
The LIFT Home Study is an observational, single-arm study designed to assess the safety of non-invasive electrical spinal stimulation (ARC Therapy) administered by the LIFT System to treat upper extremity functional deficits in…
- Trial name
- NCT05284201
- Testing
- LIFT System
- Where
- 5 sites in United States
- Volunteers
- 17 people
- Sponsor
- ONWARD Medical, Inc.
Edentulous Jaw, Periodontitis
Effect of Implant Treatment and/or Dietary Advice on the Nutrition of Edentulous Ageing Subjects
Loss of masticatory function consequent to tooth loss is associated with changes in food choices and insufficient nutrition intake.
- Trial name
- NCT05334407
- Testing
- Implant-supported full-arch fixed dental prostheses（dental intervention,DE）, Dietary intervention tailored to the dental status (dietary intervention, DI), Delayed implant-supported full-arch fixed dental prostheses（dental intervention,DE）
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Chronic Kidney Disease (Stages 4 and 5)
Kidney RISE: Randomized Integrated Supportive CarE Trial
The purpose of study is to investigate whether adding palliative care to usual chronic kidney disease (CKD) care improves symptoms and quality of life for people with CKD.
- Trial name
- NCT07741357
- Testing
- Kidney RISE
- Where
- 2 sites in United States
- Volunteers
- 280 people
- Sponsor
- NYU Langone Health
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