Clinical trials: Supportive Therapy
Autism, Aggression
The Family VOICE Study
Family centered mental health treatment with children values and supports the role of parents in their child's recovery. However, medications are often the primary focus in community treatment, even in preschool age youth, with…
- Conditions
- Autism, Aggression, Bipolar Disorder, Psychotic Disorders
- Trial name
- NCT01804582
- Testing
- Family Navigator consultation
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University of Maryland, Baltimore
Radiation-induced Oral Mucositis
Benzydamine for Radiation-Induced Oral Mucositis in Patients Receiving High-Dose Radiotherapy
This single-center, open-label, randomized clinical trial evaluates the effect of 0.15% benzydamine hydrochloride (Difflam) oral spray on the severity of radiation-induced oral mucositis in patients with head and neck cancer…
- Trial name
- NCT07467759
- Testing
- benzydamine hydrochloride, saline mouth rinse
- Where
- Syria
- Volunteers
- 35 people
- Sponsor
- Latakia University
Spinal Cord Injuries
Improving Gait in Patients With Spinal Cord Injuries
This study is part of a larger clinical trial that examines the potential of a 12-week treadmill-training program to improve walking in patients with spinal cord injuries (SCIs).
- Trial name
- NCT00060983
- Testing
- Body weight supported locomotor training, Functional electrical stimulation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Lymphoma, Non Hodgkin's Lymphoma
Cyclophosphamide, Doxorubicin, Vincristine, Prednisone, Rituximab Pateinets With Aggresive NHL
We now propose to investigate the combination of CHOP-Rituxan plus PEG-Filgrastim (PEG-filgrastim) and GM-CSF. PEG-Filgrastim would be given in order to allow us to administer the chemotherapy courses every 2 weeks with the…
- Trial name
- CHOP-R (NCT01527422)
- Testing
- Cyclophosphamide, Doxorubicin, Vincristine and Prednisone
- Where
- Puerto Rico
- Volunteers
- 60 people
- Sponsor
- Fernando Cabanillas
Pulmonary Infection, Covid-19
Triiodothyronine for the Treatment of Critically Ill Patients With COVID-19 Infection
This study is a phase II, parallel, prospective, randomized, double-blind, placebo controlled trial. The present study will aim to address the efficacy and safety of acute administration of triiodothyronine on ICU patients…
- Trial name
- Thy-Support (NCT04348513)
- Testing
- T3 solution for injection
- Where
- Greece
- Volunteers
- 5 people
- Sponsor
- Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.
Spinal Cord Injuries, Multiple Sclerosis
Functional and Physiological Responses to Lokomat Therapy (Pilot Study)
Individuals with neurological deficiencies such as those who have spinal cord injury, stroke, traumatic brain injury, Parkinson's disease, and multiple sclerosis often lose their ability to ambulate over ground.
- Conditions
- Spinal Cord Injuries, Multiple Sclerosis, Stroke
- Trial name
- NCT00883142
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- US Department of Veterans Affairs
Hepatitis C
Pilot Trial of Directly Observed Anti HCV Therapy & Contingency Management in a Population on Opiate Substitute Therapy
DOT-C is a cluster randomised trial of a pharmacist-led, directly observed anti HCV therapy pathway versus the conventional care pathway within community pharmacies.
- Trial name
- DOT-C (NCT03483818)
- Testing
- Assessment & Treatment of HCV infection with oral antivirals
- Where
- United Kingdom
- Volunteers
- 152 people
- Sponsor
- NHS Tayside
Preterm Birth, Pediatric Cancer
eHealth as an Aid for Facilitating and Supporting Self-management in Families With Long-term Childhood Illness
The overall aim is twofold: 1) to stretch the borderline regarding the present knowledge of clinical and economic cost-effectiveness of eHealth as an aid for facilitating and supporting self-management in families with long-term…
- Conditions
- Preterm Birth, Pediatric Cancer, Hirschsprung Disease, Congenital Malformation
- Trial name
- eChildHealth (NCT04150120)
- Testing
- e-health device with application, Mobile phone text messaging, early detection of cerebral palsy using a mobile phone application
- Where
- 7 sites in Denmark, Ethiopia and 1 more
- Volunteers
- 720 people
- Sponsor
- Lund University
HIV Infections, Unstable Housing
Engagement in HIV Primary Care Services
This study is to look at things that may affect whether or not people who are HIV-infected get into medical care and stay in medical care.
- Trial name
- NCT00300170
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Montefiore Medical Center
Major Depressive Disorder
Light Therapy for Elderly Depression
The purpose of this study is to investigate the following two hypotheses: 1. Treatment with bright light improves their sleep, mood, concentration and self-sufficiency of elderly depressed subjects.
- Trial name
- NCT00332670
- Testing
- 10.000lux blue 1 hour every day during three weeks, 50lux dim red 1 hour every day during three weeks
- Where
- Netherlands
- Volunteers
- 89 people
- Sponsor
- GGZ Buitenamstel
Breast Cancer
An Internet-based Psychosexual Intervention for Couples Following Treatment for Breast Cancer
Diagnosis and treatment of breast cancer often leads to lower levels of sexual desire, decreased sexual arousal, painful intercourse, and difficulties achieving orgasm, and thus adversely impacts sexual functioning and intimacy.
- Trial name
- IPSIC (NCT01881022)
- Testing
- Psychosexual Intervention
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Undernutrition, Healthy Nutrition
Women Supporting Women to Improve Infant and Child Feeding Practices
Undernutrition in the first 2 years of life is the largest preventable cause of death before age 5. Among those who survive, stunting before age two leaves millions with lifelong physical and cognitive deficits, which are…
- Conditions
- Undernutrition, Healthy Nutrition, Health Behavior, Health Knowledge, Attitudes, Practice
- Trial name
- NCT05473312
- Testing
- Community Sensitization, 28-day PD/Hearth Sessions, Supplemental Print Information
- Where
- Pakistan
- Volunteers
- 350 people
- Sponsor
- Aga Khan University
Achievement
The Positive Family Support Project - Partnering With Families for a Successful Transition to School
The Positive Family Support Project seeks to understand some of the factors that increase success for children in early elementary school, such as positive family support at home.
- Trial name
- NCT02289092
- Testing
- Family Check-Up
- Where
- United States
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Coronary Artery Bypass Graft, Non-cardiac Thoracic Surgery
Pilot Testing a Home-Based Rehabilitation Intervention Designed to Improve Outcomes of Frail Veterans Following Cardiothoracic Surgery
Frail Veterans are at increased risk for poor surgical outcomes, and as the Veteran population grows older and more frail, there is a critical need to identify effective strategies for reducing surgical risks for these patients.
- Conditions
- Coronary Artery Bypass Graft, Non-cardiac Thoracic Surgery, Frailty
- Trial name
- NCT03299101
- Testing
- Prehabilitation
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- VA Office of Research and Development
Depressive Symptoms, Depression
Virtual Therapeutic Garden for Depressive Symptoms
This study evaluates the addition of virtual therapy intervention in the treatment of depression in the elderly. Half of the participants will receive virtual reality treatment as an addition to physical exercises and…
- Conditions
- Depressive Symptoms, Depression, Anxiety
- Trial name
- NCT05285501
- Testing
- Group general fitness training, Group relaxation and psychoeduaction, VRTierOne
- Where
- 2 sites in Poland
- Volunteers
- 60 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Depression
Evaluation of the Initial Prescription of Ketamine and Milnacipran in Depression in Patients With a Progressive Disease
KetaPal is a placebo-controlled randomized trial designed to demonstrate the antidepressant action of ketamine in palliative care situations.
- Trial name
- KETAPAL (NCT02783430)
- Testing
- Ketamine, Milnacipran
- Where
- 9 sites in France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Lille
Malnutrition, Cancer-related Malnutrition
Nutritional Prehabilitation to Improve Cancer Outcomes (N-PICO)
Brief Summary The goal of this clinical trial is to evaluate the acceptability and adherence of low- and high-intensity remote nutritional interventions for cancer patients in rural and urban areas, specifically focusing on those…
- Conditions
- Malnutrition, Cancer-related Malnutrition, Quality of Life (QOL), Nutritional Support
- Trial name
- N-PICO (NCT07072377)
- Testing
- Intensity of Nutritional Intervention, Remote or In-Person
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of Vermont Medical Center
Malnourishment, Nutritional Deficiency
Nutritional Supplementation in Head and Neck Cancers
The purpose of this study is to determine whether multimodal nutrition therapy (primary nutrition intervention + adjuvant nutrition therapy) will support patients to optimize their total caloric intake during cancer treatment by…
- Conditions
- Malnourishment, Nutritional Deficiency, Undernutrition
- Trial name
- NCT05379712
- Testing
- Resource® Support Plus
- Where
- Canada
- Volunteers
- 81 people
- Sponsor
- AHS Cancer Control Alberta
Periodontitis
Clinical Efficacy of Mouthrinses Based on Chlorhexidine 0.12% and CITROX®
The goal of the following clinical trial is to compare the efficacy of a product based on chlorhexidine 0.12% and CITROX and the same product without CITROX in the healing phenomena that occur after non-surgical periodontal…
- Trial name
- NCT06341439
- Testing
- Mouthwash with chlorhexidine 0,12% and CITROX, Mouthwash with chlorhexidine 0,12%
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of L'Aquila
Advanced Cancer
FOCUSau: A Dyadic Digital Health Intervention to Improve the Wellbeing of People With Advanced Cancer and Their Carers
FOCUS is a dyadic, psychoeducational intervention developed in the USA, shown to improve the wellbeing and quality of life (QoL) of patients with advanced cancer and their primary family carers.
- Trial name
- FOCUSau (NCT06082128)
- Testing
- FOCUSau
- Where
- 5 sites in Australia
- Volunteers
- 433 people
- Sponsor
- University of Melbourne
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