Clinical trials: Supportive Therapy
Parkinson's Disease, Depression
Coping With Depression in Parkinson's Disease
The purpose of this study is to evaluate the efficacy of a cognitive-behavioral treatment, that includes a caregiver-focused social support intervention, for depression in persons with Parkinson's disease.
- Trial name
- NCT00464464
- Testing
- cognitive-behavioral therapy
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Heart Failure
ODYSSEE-vCHAT Pilot Trial for Heart Failure
INTRODUCTION Psychological distress and reduced quality of life are prevalent within the heart failure (HF) population. The 1-year rehospitalization (40%) and 5-year mortality (45% for women and 60% for men) rates are high.
- Trial name
- ODYSSEE-vCHAT (NCT04966104)
- Testing
- ODYSSEE-vCHAT
- Where
- 3 sites in Canada
- Volunteers
- 61 people
- Sponsor
- University Health Network, Toronto
Plantar Wart
Studying of Natural Constituents' Treatment of Plantar Warts
Moringa banana nigella and Banna coat extract were prepared and formulated in the form of bi gel for transdermal delivery of these plant extracts.
- Trial name
- NCT05592041
- Testing
- Banaba Leaf Extract
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Deraya University
Non-Hodgkin's Lymphoma
IMPACT Non Hodgkins Lymphoma (NHL) Study
This is multi-center, international observational study of subjects receiving CHOP-14 or CHOP-21 (with or without Rituximab) for the treatment of NHL.
- Trial name
- NCT00903812
- Testing
- No intervention
- Volunteers
- 1,837 people
- Sponsor
- Amgen
Neurocognitive Deficit, Quality of Life
WHOle Brain Irradiation or STEreotactic Radiosurgery for Five or More Brain Metastases (WHOBI-STER)
This work aims to evaluate neurocognitive performance, daily activity and quality of life and local control among patients with brain metastasis (MBM) ≥ 5 due to solid tumors treated with Stereotactic RadioSurgery (SRS) or Whole…
- Conditions
- Neurocognitive Deficit, Quality of Life, Activities of Daily Living
- Trial name
- WHOBI-STER (NCT04891471)
- Testing
- Stereotactic RadioTherapy, Whole Brain Irradiation
- Where
- 4 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Mediterranean Institute of Oncology
Oncology
Quality of Life Assessment for Early Identification of Supportive Care Needs in Oncology Patients
The aim of this study is to evaluate the value of the nurse's use of the Quality of Life (QoL) scores of the European Organisation for Research and Treatment of Cancer [EORTC] Quality of Life Questionnaire [QLQ] C30 as an aid in…
- Trial name
- SOS-DETEQT (NCT06337487)
- Testing
- QoL questionnaires, Qualitative Interview (for one part of nurses only), ORIC questionnaire
- Where
- 2 sites in France
- Volunteers
- 93 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
GnRH Agonist
Effect of GnRH Agonist in FET
To evaluate the impact of single dose GnRH agonist administration as luteal phase support on pregnancy outcomes in frozen ICSI cycle
- Trial name
- gnrh agonist (NCT07653282)
- Testing
- GnRH agonist
- Where
- Egypt
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Assiut University
HIV Antiretroviral Therapy (ART) Adherence
Hybrid Type-1 Effectiveness-Implementation Trial of Motivation Matters!
The goal of this clinical trial is to learn if an interactive mHealth intervention will be effective in helping HIV-positive women in high-burden settings who are initiating antiretroviral therapy (ART) take their ART regularly…
- Trial name
- NCT06745050
- Testing
- Text message mHealth Evidence-based intervention
- Where
- Kenya
- Volunteers
- 350 people
- Sponsor
- University of Washington
Palliative Care
Use of Online Communications to Support Patients and Their Families in the Hospice Unit
The increasing awareness of the importance of palliative care has led, in Israel, to the 2005 Law for the Rights of Persons with Terminal Illness. Still, problems of accessibility to palliative care remain unresolved.
- Trial name
- NCT02483390
- Testing
- psychosocial intervention
- Volunteers
- 20 people
- Sponsor
- Pesach Shvartzman
Eating Disorders in Adolescence, Transition of Care
Feasibility of the TransitionED Framework for Youth and Young Adults With Eating Disorders
Moving from pediatric (children's) health care to adult health care can be challenging for youth and young adults with eating disorders.
- Trial name
- TransitionED 3 (NCT07518641)
- Testing
- TransitionED Healthcare Transition Framework
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- McMaster University
Mesothelioma
A Study Comparing Pemetrexed Plus Best Supportive Care Versus Best Supportive Care Alone in the Treatment of Mesothelioma
Based on results from earlier clinical trials, Pemetrexed may have antitumor activity as a first-line agent in the treatment of mesothelioma.
- Trial name
- NCT00190762
- Testing
- Pemetrexed
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- Eli Lilly and Company
Transitional Cell Carcinoma of the Urothelial Tract, Bladder Cancer
Phase III Trial of Vinflunine Plus Best Supportive Care vs. Best Supportive Care in Patients With Transitional Cell Carcinoma (TCC) of the Urothelial Tract
The purpose of this clinical research study is to learn if patients who receive vinflunine plus best supportive care live longer than patients who receive best supportive care alone.
- Conditions
- Transitional Cell Carcinoma of the Urothelial Tract, Bladder Cancer, Bladder Neoplasms
- Trial name
- NCT00315237
- Testing
- vinflunine and best supportive care
- Where
- 10 sites in Canada
- Volunteers
- 364 people
- Sponsor
- Pierre Fabre Medicament
Atrial Fibrillation
Supporting Use of AC Through Provider Profiling of Oral AC Therapy for AF IV
Six million Americans live with atrial fibrillation (AF), a heart rhythm abnormality that is a major risk factor for stroke and only half of those AF patients receive oral anticoagulation (AC).
- Trial name
- SUPPORT-AF IV (NCT05236556)
- Testing
- Best practice advisory (BPA)
- Where
- 2 sites in United States
- Volunteers
- 5,094 people
- Sponsor
- University of Massachusetts, Worcester
Severe Mental Illness, Bipolar Disorder
A Mobile App to Support Mood, Daily Routines and Medication Adherence in Adults With Severe Mental Illness
The goal of this clinical trial is to learn whether MoodSync, a mobile application for patients and their family caregivers, improves mood stability, medication adherence, daily functioning and early detection of relapse warning…
- Conditions
- Severe Mental Illness, Bipolar Disorder, Schizophrenia, Schizoaffective Disorder
- Trial name
- MoodSync (NCT07879131)
- Testing
- MoodSync, Standard care
- Where
- Bahrain
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Heart Diseases
Pain Assessment, Incidence & Nature in Heart Failure
Heart failure, a chronic illness afflicting 5 million persons in the United States is known to cause shortness of breath and fatigue, yet at least half of persons with heart failure also report the presence of pain.
- Trial name
- PAIN-HF (NCT00444301)
- Where
- 14 sites in United States
- Volunteers
- 349 people
- Sponsor
- PC-HEART
Medication Adherence, Hypertension
Evaluation of a Decision Support Tool
Investigators will conduct a randomized trial with patients, through one-on-one interviews, to evaluate their understanding of and willingness to use a decision support tool and to determine if receiving and discussing the…
- Conditions
- Medication Adherence, Hypertension, Decision Making, Shared, Patient-Centered Outcomes Research
- Trial name
- PRIMA (NCT02060981)
- Testing
- Control, Interview Only, Interview plus decision support tool
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Brigham and Women's Hospital
Non Small Cell Lung Cancer
Erlotinib Pharmacokinetics During Doxycycline Treatment for Erlotinib-induced Rash
A side effect occurring in a majority of patients taking erlotinib (Tarceva®) consists of a skin rash. Sometimes, symptoms associated with the rash necessitate erlotinib dose reduction or discontinuation.
- Trial name
- NCT00803842
- Testing
- doxycycline
- Sponsor
- Northwestern University
Substance Use Disorders, Alcohol Abuse
Reinforcement of Abstinence and Continuing Care in Substance Abuse Treatment
The Contracts, Prompts, and Social Reinforcement (CPR) intervention was designed to address the continuing care adherence needs of veterans presenting for substance use disorder (SUD) treatment.
- Conditions
- Substance Use Disorders, Alcohol Abuse, Alcoholism, Substance Dependence
- Trial name
- NCT00288886
- Testing
- Contracting, Prompting and Reinforcement arm, Control arm
- Where
- 2 sites in United States
- Volunteers
- 183 people
- Sponsor
- US Department of Veterans Affairs
Hepatitis C, Chronic
Multidisciplinary Support Program in Chronic Hepatitis C
Adherence to antiviral treatment in chronic hepatitis C (CHC) is an important factor to achieve sustained virological response (SVR).
- Trial name
- NCT01850745
- Testing
- Multidisciplinary support program
- Where
- Spain
- Volunteers
- 447 people
- Sponsor
- Parc de Salut Mar
Myelodysplastic Syndromes
An Extension to Study AZA PH GL 2003 CL 001 Allowing for Continuation of Azacitidine Treatment in Patients With Myelodysplastic Syndromes (MDS)
At the conclusion of study AZA PH GL 2003 CL 001 (NCT00071799), eligible participants could be enrolled in an optional extension phase in order to continue treatment with azacitidine until it became commercially available; the…
- Trial name
- NCT01186939
- Testing
- Azacitidine
- Where
- 22 sites in Australia, Bulgaria and 9 more
- Volunteers
- 40 people
- Sponsor
- Celgene
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