Clinical trials: Supportive Therapy
Short Bowel Syndrome
A Study of Teduglutide in Chinese Adults With Short Bowel Syndrome
The main aim of the study is to assess how well teduglutide works over 24 weeks in Chinese adult participants with short bowel syndrome (SBS) who need parenteral support and to see how much it can reduce the amount of parenteral…
- Trial name
- NCT06973304
- Testing
- Teduglutide
- Where
- 4 sites in China
- Volunteers
- 13 people
- Sponsor
- Takeda
Autistic Disorder, Autism Spectrum Disorder
Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder
This study will investigate and contrast the effects of two psychological treatments for adults with autism spectrum disorder. Cognitive Enhancement Therapy (CET) is a cognitive remediation intervention that aims to help adults…
- Conditions
- Autistic Disorder, Autism Spectrum Disorder, Asperger's Syndrome, Pervasive Developmental Disorder
- Trial name
- Perspectives (NCT00902798)
- Testing
- Cognitive Enhancement Therapy, Enriched Supportive Therapy
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Pittsburgh
Dementia
Effectiveness and Cost-effectiveness of vCST and Online Dementia Carer Support
A multicentre single-blind cluster randomised trial to evaluate the effectiveness and cost-effectiveness of virtually delivered versus in-person cognitive stimulation therapy (CST) and carer support in people living with dementia…
- Trial name
- NCT05783414
- Testing
- f2f CST, f2f carer support, vCST
- Where
- Hong Kong
- Volunteers
- 156 people
- Sponsor
- The University of Hong Kong
Stroke, Difficulty Walking
Body Weight Supported Treadmill Training vs. Overground Walking Training in Persons With Chronic Stroke
The purpose of this study is to compare two different walking training programs for persons with chronic stroke.
- Trial name
- NCT01180738
- Testing
- Body weight supported treadmill training, Overground walking training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stephanie Miller
Head and Neck Squamous Cell Carcinoma, Locally Advanced Rectal Cancer
GALENOS 1 in Head and Neck, Lung, and Rectal Cancer Patients
GALENOS 1 is a prospective observational study designed to explore longitudinal changes in nutritional status and body composition in patients with head and neck squamous cell carcinoma, locally advanced rectal cancer, and lung…
- Conditions
- Head and Neck Squamous Cell Carcinoma, Locally Advanced Rectal Cancer, Lung Cancer
- Trial name
- GALENOS 1 (NCT07511413)
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Medication Adherence
Investigation of a Patient Support Intervention for Statin Medication Adherence
Statins have been demonstrated to significantly reduce the risk of cardiovascular disease, but adherence to these medications is suboptimal.
- Trial name
- NCT06972979
- Testing
- Text Message Gamification and Remote Support
- Where
- United States
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Ascension Health
Central Nervous System Cancer, Psychological Distress
Interest of a TEteleconsultation of a Psychological Support Nurse on Psychological Distress in Patients With a Primary Malignancy of the Central Nervous System
The goal of this clinal trial is to compare the effectiveness of nurse-led teleconsultation with usual care (intervention group) on psychological distress in patients with primary malignant tumors of the central nervous system…
- Trial name
- TECAP (NCT06485310)
- Testing
- Teleconsultation for psychological support
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Myelodysplastic Syndromes
Antithymocyte Globulin Compared With Supportive Care in Treating Patients With Myelodysplastic Syndrome
RATIONALE: Immunosuppressive therapy may improve bone marrow abnormalities and may be effective treatment for myelodysplastic syndrome.
- Trial name
- NCT00017550
- Testing
- anti-thymocyte globulin
- Where
- 28 sites in United States, Canada
- Sponsor
- Genzyme, a Sanofi Company
Triple Negative Breast Cancer, Non-small Cell Lung Cancer
A Biomarker Screening Protocol for Participants With Solid Tumors
Biomarker Screening Protocol for Preliminary Eligibility Determination for Adoptive T-cell Therapy Trials:This is a decentralized, multi-site, US-based biomarker screening study to identify participants who have specific disease…
- Conditions
- Triple Negative Breast Cancer, Non-small Cell Lung Cancer, Non Small Cell Lung Cancer, Non Small Cell Lung Cancer Metastatic
- Trial name
- START (NCT05891197)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Lyell Immunopharma, Inc.
Hypoxia
Clinical Validation of Vital-PICASO for Predicting Hypoxia Within 24 Hours in General Ward Inpatients
The purpose of this retrospective study is to evaluate the clinical performance of Vital-PICASO, an artificial intelligence-based biological signal analysis software designed to predict the risk of hypoxia within 24 hours using…
- Trial name
- NCT07742813
- Where
- South Korea
- Volunteers
- 2,250 people
- Sponsor
- Huinno AIM
Anemia, Sickle Cell
Systematic Psychological and Medical Care for Children With SCD
Sickle cell disease (SCD), a genetically transmitted blood disease, necessitates life-long care. In children, the disease may cause intense pain and other severe complications.
- Trial name
- Drépano (NCT02022891)
- Testing
- systematic psychological care
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Psychosis, Schizophrenia
VR Therapy for Psychosis Negative Symptoms (V-NeST)
Background: Negative symptoms are typically observed in people with schizophrenia and indicate a loss or reduction of a normal function (e.g. reduced motivation and affect display).
- Trial name
- V-NeST (NCT03995420)
- Testing
- Virtual Reality Therapy (V-NeST), Treatment as Usual
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Institute of Psychiatry, London
Acute Low Back Pain
Psychosocial Treatment for Acute Low Back Pain
Acute low back pain (severe pain that comes on suddenly and lasts a relatively short time) is very common in the United States, and accounts for substantial illness, functional limitations, pain, and health care costs.
- Trial name
- NCT00000418
- Testing
- Psychosocial intervention
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- Indiana University
Heart Failure
Image Supported Lead Placement in CRT
Cardiac resynchronization therapy (CRT) is an established pacemaker therapy for patients with symptomatic chronic heart failure, but is hampered by a non-response rate of 30-40%.
- Trial name
- ADVISE (NCT05053568)
- Testing
- CARTBox
- Where
- 7 sites in Netherlands
- Volunteers
- 130 people
- Sponsor
- UMC Utrecht
Respiratory Distress Syndrome, Newborn, Infant, Newborn
Feasibility of Uninterrupted Infant Respiratory Support Treatment
Feasibility study of a simplified respiratory support system for newborn infants
- Conditions
- Respiratory Distress Syndrome, Newborn, Infant, Newborn, Respiratory Insufficiency Syndrome of Newborn
- Trial name
- FUIRST (NCT04244890)
- Testing
- Uninterrupted CPAP for the first hours of life
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Karolinska Institutet
Autism Spectrum Disorder, Obesity, Childhood
Family, Responsibility, Education, Support, and Health for Families With a Child With Autism
The objective of this proposed study is to collect initial efficacy data on a telehealth parent-based behavioral program for children with autism and overweight or obesity (PBT-A), compared with health education (HE).
- Conditions
- Autism Spectrum Disorder, Obesity, Childhood, Autism
- Trial name
- FRESH-A (NCT05741840)
- Testing
- PBT-A, Health Education (HE)
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Breast Cancer
Comparative Evaluation of Osteopathy Treatment Efficacy in Pain Support After Breast Surgery in Oncology
This is an open, prospective, controlled, randomized, comparative study with 2 arms. The purpose of the study is to assess the efficacy of osteopathy after breast surgery. 80 patients will be enrolled, 40 per arm.
- Trial name
- OSTEOPATHIE (NCT01403168)
- Testing
- OSTEOPATHY + conventional analgesic treatments, Conventional analgesic treatments
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Centre Leon Berard
Virtual Reality, Quality of Life
Virtual Reality Therapy for Improving Caregiver and Patient Quality of Life in Home-Based Palliative Care in Saudi Arabia
This randomized controlled trial evaluates the efficacy of a culturally adapted virtual reality (VR) nature therapy intervention aimed at improving the quality of life (QOL) and emotional well-being of palliative patients and…
- Conditions
- Virtual Reality, Quality of Life, Palliative Care, Caregivers
- Trial name
- VIRTIC-Hajj (NCT07567391)
- Testing
- Immersive Nature VR
- Volunteers
- 100 people
- Sponsor
- University of Bisha
Hypertension, Blood Pressure
Check and Support -Enhancing the Treatment of Hypertension in Outpatient Care, a Multicenter Study
The purpose of this pragmatic multi-centre, cluster randomized controlled trial is to test the effectiveness of tailored SMS-text message support combined with an information-motivation-behavioral skills (IMB) model-based…
- Conditions
- Hypertension, Blood Pressure, Patient Compliance, Patient Adherence
- Trial name
- NCT02377960
- Testing
- IMB model-based initiation of antihypertensive medication, Tailored SMS-text message support, Usual care
- Where
- 6 sites in Finland
- Volunteers
- 119 people
- Sponsor
- Kuopio University Hospital
Adherence, Medication, HIV-1-infection
Supporting Treatment Adherence for Resilience and Thriving (START)
This Phase II randomized controlled trial is testing the efficacy of a cell phone application called START for helping men who use stimulants like methamphetamine to get the most out of their HIV treatment.
- Conditions
- Adherence, Medication, HIV-1-infection, Stimulant Use
- Trial name
- START (NCT05140876)
- Testing
- START mHealth Intervention
- Where
- United States
- Volunteers
- 286 people
- Sponsor
- Florida International University
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