Clinical trials: Supportive Therapy
Decision Making, Choice Behavior
Impact of a Decision Aid Regarding Natural Health Products for Menopausal Symptoms
The aim of this study is to assess the impact of a patient decision aid regarding natural health products for menopausal symptoms on decisional conflict, knowledge and persistence for an option of women aged 45-64 years old.
- Conditions
- Decision Making, Choice Behavior, Decision Support Techniques, Decision Aids
- Trial name
- NCT00325923
- Testing
- Decision aid
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Allogeneic Hematopoietic Stem Cell Transplantation
Humor Therapy and Distress After Allogeneic Stem Cell Transplantation
This research study evaluates the impact of a humor intervention on distress (primary outcome), hope, depressive symptoms, anxiety, and pain (secondary outcomes) in patients undergoing allogeneic hematopoietic stem cell…
- Trial name
- NCT03593161
- Testing
- Humor therapy
- Where
- Germany
- Volunteers
- 126 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Dyspnea
Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology
To learn about the effect of Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology (SPOT-ON) treatment on the severity of shortness of breath in patients with cancer.
- Trial name
- NCT06336642
- Testing
- SPOT-ON Early Start, SPOT-ON Delayed Start
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- M.D. Anderson Cancer Center
Heart Failure, Heart Failure With Reduced Ejection Fraction
Building Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations - Heart Failure (BETTER CARE-HF)
Building Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations - Heart Failure (BETTER CARE-HF) is a pragmatic, cluster-randomized, three-arm intervention trial that will compare the effectiveness of two…
- Trial name
- BETTER CARE-HF (NCT05275920)
- Testing
- Best Practice Alert (BPA), In-Basket Message
- Where
- United States
- Volunteers
- 2,211 people
- Sponsor
- NYU Langone Health
Breast Cancer
The Immersive Experience of Virtual Reality During Chemotherapy in Patients With Early Breast and Gynecological Cancers: the Patient's Dream Study
"Patient's dream" study is a two-arm randomized controlled trial that will be conducted at Regina Elena National Cancer Institute, IRCCS (Rome), from April 2019 to January 2020.
- Trial name
- NCT05234996
- Testing
- 3 Virtual Reality headset (VR Headset),
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lung Neoplasm, Melanoma
Clinical Trial of Telenursing for Monitoring Supportive Care Needs in Patients With Lung Cancer and Melanoma Candidates for the First Prescription of Targeted Therapies
Single-center, randomized clinical trial (RCT) with low intervention level (Telenursing), for the monitoring of patients affected by lung cancer and melanoma who are candidates for first prescription with Targeted Therapies.
- Trial name
- Telenursing (NCT06254196)
- Testing
- Telenursing interventions for monitoring Supportive Care Needs
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Regina Elena Cancer Institute
Relationship Distress
A Pilot of the Brief Relationship Checkup
The goal of this pilot trial is to study the Brief Relationship Checkup (BRC) program for Veterans with a combination of mental health and relationship concerns.
- Trial name
- BRC (NCT06011161)
- Testing
- Brief Relationship Checkup (BRC)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Canandaigua VA Medical Center
Sickle Cell Disease
A Phase - IIa - IIb, Trial to Study the Safety, Tolerability and Efficacy of Memantine as a Long-term Treatment of SCD
Symptomatic sickle cell disease (SCD) is worldwide the most frequent cause for hereditary hemolytic anemia with recurrent pain crises.
- Trial name
- MeMAGEN (NCT03247218)
- Testing
- Memantine Hydrochloride
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- HaEmek Medical Center, Israel
ExtraCorporeal Life Support (ECLS), Wound Infection
Investigating the Impact of Cold Atmospheric Plasma Treatment on Wound Healing at Cannulation Sites in Patients Following Extracorporeal Life Support
This study aims to evaluate a new wound treatment called cold atmospheric plasma (CAP) for patients receiving extracorporeal life support (ECLS).
- Conditions
- ExtraCorporeal Life Support (ECLS), Wound Infection, Surgical Site Infection, Delayed Wound Healing
- Trial name
- NCT07501897
- Testing
- Cold Atmospheric Plasma (CAP) Therapy, Standard wound care
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- National Taiwan University Hospital
Bone Loss, Peri-Implantitis
(PEKK) Framework for Mandibular Implant-supported Complete Fixed Prostheses
This clinical study aims to evaluate the effect of using PEKK (Pekkton) framework in mandibular implant-supported complete fixed dental prostheses with All-on-four treatment concept on peri-implant tissues health
- Trial name
- NCT06164990
- Testing
- PEKK framework
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Fatma mahanna
Myelodysplastic Syndrome
A Study Comparing Siltuximab Plus Best Supportive Care to Placebo Plus Best Supportive Care in Anemic Patients With International Prognostic Scoring System Low- or Intermediate-1-Risk Myelodysplastic Syndrome
The purpose of this study is to evaluate the efficacy of siltuximab, demonstrated by a reduction in red blood cell (RBC), transfusions to treat the anemia of Myelodysplastic Syndrome (MDS).
- Trial name
- NCT01513317
- Testing
- Siltuximab, Best supportive care (BSC)
- Where
- 23 sites in United States, Australia and 5 more
- Volunteers
- 76 people
- Sponsor
- Janssen Research & Development, LLC
Depression in Adolescence
Streamlined Treatment and Evidence-based Adolescent Counseling and Medication Support (STREAMS)
Combination interventions to address mental health and adherence to HIV care in low- and middle-income countries (LMICs), are crucial to achieving the UNAIDS 95-95-95 targets as one in four adolescents living with HIV (ALWHIV)…
- Trial name
- STREAMS (NCT07637058)
- Testing
- Streamlined Suubi+Adherence, Streamlined Interpersonal Psychotherapy Groups (IPT-G)
- Volunteers
- 588 people
- Sponsor
- City University of New York, School of Public Health
Immunization
Music Therapy as Procedural Support for Young Children Undergoing Immunizations
Many young children undergo medical procedures that are painful and distressing. Negative experiences during medical procedures can have serious long-term effects, including fear and avoidance of medical procedures during…
- Trial name
- NCT01463176
- Testing
- Music Therapy
- Where
- 3 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Florida State University
MDS, AML, Adult
Quality of Life-Guided Transfusion in Refractory MDS or AML
Patients with refractory myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML) in exclusive palliative care frequently receive red blood cell transfusions based on hemoglobin thresholds, despite limited evidence of…
- Conditions
- MDS, AML, Adult, Anemia
- Trial name
- Q-TRANS (NCT07328191)
- Testing
- Red blood cell transfusions based on EQ-5D-5L questionnaire
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Cardiac Rehabilitation, Healthy Lifestyle
Web Based Cardiac Rehabilitation Support in Coronary Artery Patients
This study was carried out as a randomized controlled experimental study to evaluate the effect of web-based cardiac rehabilitation support on the healthy lifestyle behaviors, medication adherence and quality of life in coronary…
- Conditions
- Cardiac Rehabilitation, Healthy Lifestyle, Medication Adherence, Quality of Life
- Trial name
- NCT05489913
- Testing
- cardiac rehabilitation support program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Semiha ALKAN KAYHAN
Arterial Hypertension, Cardiovascular Diseases
Telemedical Algorithm-Supported Care for Hypertension
Hypertension is a major global health issue, affecting around 9 million people in Poland. While some studies indicate that telemonitoring benefits patients with hypertension, there is a lack of research evaluating tools that…
- Trial name
- SOT-ART-HT (NCT06722625)
- Testing
- Evaluation of a blood pressure monitoring system with an integrated algorithm that supports the doctor's decision-making process
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Poznan University of Medical Sciences
Human Immunodeficiency Virus
Using Social Media to Improve ART Retention and Treatment Outcomes Among YLHIV in Nigeria
A randomized control trial to test the effectiveness of a structured online support group, SMART (Social Media to improve ART Retention in Treatment) Connections, to improve retention in HIV care services among youth living with…
- Trial name
- Y-SMART (NCT03516318)
- Testing
- SMART Connections
- Where
- Nigeria
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- FHI 360
Generalized Anxiety Disorder (GAD), Major Depressive Disorder (MDD)
AI-Supported Therapy for Depression and Anxiety Compared With Standard CBT
This study is a pivotal, randomised, controlled, non-inferiority trial evaluating "Nook," an AI-delivered, neurosymbolic, clinician-supervised digital psychological intervention for depression and anxiety, compared with standard…
- Trial name
- NCT07620340
- Testing
- AI-Digital CBT, Cognitive Behavioural Therapy
- Volunteers
- 400 people
- Sponsor
- PsyScale
Workplace Culture, Help-Seeking Behavior
Evaluating a Physician Opinion Leader Intervention to Increase Utilization of Coaching/Therapy During Residency
Investigators will assess the efficacy of a physician popular opinion leader-led intervention to increase awareness and utilization of existing evidence-based coaching or therapy among post-graduate clinical trainees at Stanford.
- Conditions
- Workplace Culture, Help-Seeking Behavior, Social Stigma, Education, Medical, Continuing
- Trial name
- POL (NCT05499468)
- Testing
- Popular-Opinion Leader-led encouragement during training meetings and informal conversation
- Where
- United States
- Volunteers
- 493 people, healthy volunteers welcome
- Sponsor
- Stanford University
Insomnia
dCBTi With and Without Coaching Support
The current research aims to evaluate the adherence and efficacy of dCBTi with different types of coaching support.
- Trial name
- NCT05136638
- Testing
- dCBTi, Virtual coaching, Non-therapist coaching
- Where
- Hong Kong
- Volunteers
- 129 people
- Sponsor
- The University of Hong Kong
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