Clinical trials: Supportive Therapy
Airway Obstruction, Foreign-Body, Cardiopulmonary Resuscitation
Cardiopulmonary Resuscitation and Choking Management Education for Caregivers of Infants Under 1 Year: Comparison Between Practical Workshop and Informational Leaflet
Objective: to evaluate the effectiveness of an educational workshop versus standard information in improving knowledge and perceived self-efficacy in basic life support.
- Conditions
- Airway Obstruction, Foreign-Body, Cardiopulmonary Resuscitation, Infant, Health Education
- Trial name
- NCT07567638
- Testing
- Explanation of the informational sheet, Theoretical-practical workshop
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Marqués de Valdecilla
Squamous Cell Carcinoma of Esophagus
Benefit of Chemotherapy Over Best Supportive Care in Metastatic and Squamous Cell-type Esophageal Cancer.
Interest of continuing systemic chemotherapy or not , after a short initial treatment (6 weeks) in patients who are in response or stable disease("Discontinuation design ")of patients with metastatic oesophageal cancer of…
- Trial name
- E-DIS (NCT01248299)
- Testing
- FU-CDDP, LV5FU2-CDDP, FOLFOX
- Where
- 17 sites in France
- Volunteers
- 105 people
- Sponsor
- Centre Oscar Lambret
Heart Failure, Cardiogenic Shock
INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery
The study will evaluate the impact of a combined device-drug strategy with Impella 5.5 with best practices and optimized GDMT on heart recovery outcomes in patients with decompensated heart failure and cardiogenic shock.
- Conditions
- Heart Failure, Cardiogenic Shock, Reduced Ejection Fraction Heart Failure
- Trial name
- INTeGRATE (NCT06965504)
- Testing
- Impella 5.5 SmartAssist
- Where
- 17 sites in United States
- Volunteers
- 250 people
- Sponsor
- Abiomed Inc.
No Condition
Understanding How Peer Support Helps in Mental Health Care
The goal of this observational study is to better understand the psychological processes associated with professional peer support among adults using psychiatric services.
- Trial name
- PAIR-PROS (NCT07849621)
- Testing
- Perceptions of professional peer support and mental health professional support
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University of Bordeaux
Pain, Chronic, Opioid Use
Pain Management Support Study for Cancer Survivors
Pain in cancer survivors is difficult to treat, and unrelieved pain can greatly reduce a person's quality of life. Opioids are often prescribed for pain management, yet they can have undesirable side effects and may put someone…
- Trial name
- NCT03782506
- Testing
- Interactive Music Therapy, Verbal-based support
- Where
- 3 sites in United States
- Volunteers
- 27 people
- Sponsor
- Drexel University
Gynecologic Examination, Pain
Vaginal Examination Drape Supporting Women's Privacy
This single-blind, parallel-group randomised controlled trial evaluates whether a vaginal examination drape designed to support women's privacy reduces pain and improves perceived privacy and examination satisfaction during…
- Conditions
- Gynecologic Examination, Pain, Patient Satisfaction, Privacy
- Trial name
- PRIV-DRAPE (NCT07797309)
- Testing
- Privacy-supporting vaginal examination drape
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- KTO Karatay University
Lung Cancer
Gemcitabine Plus Supportive Care in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Treatment plus supportive care may improve quality of life in patients undergoing cancer treatment.
- Trial name
- NCT00022009
- Testing
- gemcitabine hydrochloride
- Where
- United Kingdom
- Sponsor
- The Christie NHS Foundation Trust
Hypotension
Study of Dopamine Versus Vasopressin for Treatment of Low Blood Pressure in Low Birth Weight Infants
Low blood pressure or hypotension is a very important problem that is often seen in premature babies, especially those with low birth weight.
- Trial name
- NCT01318278
- Testing
- Dopamine, Arginine Vasopressin
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Baylor College of Medicine
Neoplasm Metastasis
A Patient Navigation Program to Increase Access to Early Supportive Care in Patients With Stage IV Solid Tumors
In this randomized clinical trial, patients with Stage IV solid tumors will be enrolled in a patient navigator-led generalist palliative and supportive care intervention or in usual care led by their treating physician.
- Trial name
- NCT03293849
- Testing
- Patient Navigation
- Where
- Mexico
- Volunteers
- 134 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Multiple Myeloma
Study of Carfilzomib in Multiple Myeloma Relapsed After High-dose Melphalan With Autologous Stem Cell Support
This study evaluates induction therapy with carfilzomib-cyclophosphamide-dexamethasone before salvage high-dose melphalan with autologous stem cell support (HDT) in multiple myeloma patients with relapse after HDT done at…
- Trial name
- CARFI (NCT02572492)
- Testing
- Induction with CAR-CY-DEX and conditioning with carfilzomib and highdose melphalan, Carfilzomib/dexamethasone maintenance, Observation without carfilzomib/dexamethasone maintenance
- Where
- 5 sites in Denmark, Finland and 3 more
- Volunteers
- 200 people
- Sponsor
- Henrik Gregersen
Breast Cancer
Large Language Models to Aid Gynecological Oncology Treatment
This trial aims to assess the impact of providing medical students with access to large language models, in comparison to treatment guideline pdfs, on treatment concordance with a conventional multidisciplinary tumor board
- Trial name
- EASING (NCT06865534)
- Testing
- Local language model, Guideline pdf
- Where
- Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Cancer, Older Adults
Comprehensive Health Assessment for my Cancer Treatment Plan
Geriatric assessment (GA) predicts treatment toxicity and overall mortality in older adults with cancer. To improve treatment decision making in older adults with cancer, the American Society of Clinical Oncology (ASCO) and the…
- Trial name
- CHAMP-F (NCT05499975)
- Testing
- Self-reported online geriatric assessment (CHAMP)
- Where
- 3 sites in Canada
- Volunteers
- 180 people
- Sponsor
- University Health Network, Toronto
Congestive Heart Failure
Study to Evaluate the Safety of Twice Daily Oral Carvedilol
The objective of this study is to evaluate the long-term safety of carvedilol in pediatric patients with chronic heart failure, who completed the Pediatric Carvedilol Study 321.
- Trial name
- NCT00129363
- Testing
- Carvedilol
- Where
- 17 sites in United States
- Volunteers
- 75 people
- Sponsor
- Shaddy, Robert, M.D.
Prosthetic Treatment, Occlusal Analysis
Digitalization of Maxillo-mandibular Relation for Arches With Occlusal Support Loss
Accurate recording of the intermaxillary relationship is crucial for achieving successful restorative outcomes. In cases of occlusal support loss, determining and recording the intermaxillary relationship becomes more complex.
- Conditions
- Prosthetic Treatment, Occlusal Analysis, Digitalism
- Trial name
- NCT06982898
- Testing
- Fixed prosthesis with bimanual CR and intraoral scan
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Kıvanç Akça
Multiple Myeloma, Myeloma, Multiple
Study of the Immune Response After Vaccination in Multiple Myeloma Patients
This study will collect blood samples from healthy volunteers and volunteers with multiple myeloma who are going to get the seasonal flu, pneumonia, haemophilus influenzae B (HIB), and/or meningococcus vaccines.
- Conditions
- Multiple Myeloma, Myeloma, Multiple, Myeloma-Multiple
- Trial name
- NCT02294487
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Mothers, Infantile Colic
Supportive Care Training Given to Mothers of Babies With Infants Colic
Infantile Colic is a non-pathological condition that causes babies to cry excessively throughout their first few months of life.
- Trial name
- NCT06197100
- Testing
- Supportive care training, control grups
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Platinum-sensitive Ovarian Cancer, Relapsed Ovarian Cancer
OSE2101 Alone or in Combination With Pembrolizumab vs BSC in Patient With Platinum-sensitive Recurrent OC
The proposed study is an international randomized phase II, multicenter, open-label, three arms trial to assess best supportive care (BSC) vs OSE2101 and vs OSE2101 + pembrolizumab as maintenance treatment for patients with…
- Trial name
- TEDOVA (NCT04713514)
- Testing
- OSE2101, Pembrolizumab 25 MG/ML [Keytruda]
- Where
- 41 sites in Belgium, France and 1 more
- Volunteers
- 185 people
- Sponsor
- ARCAGY/ GINECO GROUP
Neuroblastoma, High-risk Neuroblastoma
Resource Intervention to Support Equity (RISE) in High-Risk Neuroblastoma
The goal of this study is to test if the addition of a novel income-poverty targeted supportive care intervention (Pediatric Resource Intervention to Support Equity [Pediatric RISE]) to usual supportive care for low-income…
- Trial name
- RISE in HR NBL (NCT06831552)
- Testing
- RISE Intervention
- Where
- 6 sites in United States
- Volunteers
- 84 people
- Sponsor
- Dana-Farber Cancer Institute
Pathological Gambling
Minimal and Brief Treatments for Pathological Gamblers
The purpose of the study is to examine whether problem gamblers who receive therapy calls in addition to a self-help manual will be more likely to quit or cut back on their gambling when compared with problem gamblers who receive…
- Trial name
- NCT00203645
- Testing
- Self-help treatment
- Where
- Canada
- Volunteers
- 312 people
- Sponsor
- University of Calgary
Cognitive Impairments, Stroke
Digital Support for People With Cognitive Impairment
Cognitive impairment may cause problems in planning and initiating daily activities, as well as remembering to do what is scheduled.
- Conditions
- Cognitive Impairments, Stroke, Brain Injuries
- Trial name
- NCT04470219
- Testing
- Cognitive support by RemindMe
- Where
- Sweden
- Volunteers
- 16 people
- Sponsor
- Linkoeping University
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