Clinical trials: Surgery, Cardiovascular
Congenital Heart Disease
Ultrasound-Guided Serratus Anterior Plane Block Versus Erector Spinae Plane Block in Pediatric Cardiac Surgery
Background and Objectives: Opioid based analgesia is the main used technique in pediatric cardiac surgery which preclude fast-track recovery.
- Trial name
- NCT05526469
- Testing
- Serratus anterior plane block, erector spinae plane blocks, Bupivacaine 0.25% Injectable Solution
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
Age Problem, Aortic Valve Disease
Frailty in Elderly Patients Receiving Surgical or Percutaneous Procedures for Valvular Disorders
In Italy, life expectancy at birth has reached 80 years in men and 85 in women; in about 50 years, life expectancy at the age of 80 has increased by an extraordinary 61% and 55%, respectively, due to more effective therapies and…
- Conditions
- Age Problem, Aortic Valve Disease, Mitral Valve Disease
- Trial name
- FRASER-VD (NCT03365453)
- Testing
- frailty evaluation
- Where
- Italy
- Volunteers
- 450 people
- Sponsor
- University Hospital of Ferrara
Atrial Fibrillation, Left Ventricular Diastolic Dysfunction
Characterizing Patients With POAF in Relation to Cardiac Surgery by wavECG and TTE
Post-operative atrial fibrillation (POAF) is frequently observed after open-heart surgery. Despite numerous attempts to predict POAF, it remains a challenge to correctly identify the patients at risk.
- Trial name
- NCT03962166
- Where
- Denmark
- Volunteers
- 353 people
- Sponsor
- Helena DOMINGUEZ
Preoperative Fasting and Hypotension
Effect of the Duration of Preoperative Fasting on Hypotension Induced by General Anesthesia in the Elderly Person
This study aims to determine if prolonged fasting represents an independent risk factor for hypotension during induction of general anesthesia in the elderly.
- Trial name
- JEÛNE PREOP (NCT02891122)
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Brest
Sleep Quality, Pain
Comparing the Efficacy of Earplugs and Eye Masks on Pain and Sleep Quality
Objective: To determine the superiority of earplugs and eye masks to each other and their efficacy in pain and sleep quality. Methods: The study was a three-arm randomised controlled trial.
- Conditions
- Sleep Quality, Pain, Intensive Care Medicine, Cardiac Surgery
- Trial name
- NCT07100002
- Testing
- Control Group, Earplug Group, Eye mask Group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Giresun University
Intraoperative Bleeding
The Efficacy of the Administration of Fibrinogen in Liver Transplantation
Objective: To evaluate the efficacy of preoperative administration of fibrinogen in liver transplantation by maintaining a preoperative plasma level equal to 2.9 g / L compared with placebo, reflecting a reduction in the number…
- Trial name
- FibstudLT (NCT01539057)
- Testing
- Fibrinogen, Saline
- Where
- 4 sites in Spain
- Volunteers
- 132 people
- Sponsor
- Hospital Universitari de Bellvitge
Deep Venous Thrombosis
Low Molecular Weight Heparin vs Direct Oral Anticoagulant After Bariatric Surgery
Extended Venous Thromboemboism Prophylaxis After Bariatric Surgeries: A Comparison Of Low Molecular Weight Heparin With Direct Oral Anticoagulant
- Trial name
- NCT06913595
- Testing
- Direct Oral Anticoagulant., Low Molecular Weight Heparine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Cardiac Diseases
The Effect of Perioperative Medications on the Outcomes of Patients Undergoing Cardiac Surgery
This study will be a retrospective study. The patient data from the electronic medical records and existing database will be collected and analyzed.
- Trial name
- NCT01683448
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
IHD, Valve Heart Disease
Role of Chest Ultrasound in Detection of Post-operative Pulmonary Complications After Cardiothoracic Surgery
assess feasibility of detecting pulmonary complications postoperative using chest ultrasound compared to chest x-ray measure time lag between using ultrasound and using chest x-ray to detect pulmonary complications postoperative
- Conditions
- IHD, Valve Heart Disease, Surgery--Complications
- Trial name
- NCT04118621
- Testing
- chest ultrasound
- Volunteers
- 100 people
- Sponsor
- Assiut University
Cardiac Surgery
Outcomes Study of Glycosylated Hemoglobin Control in Cox-Maze IV During Cardiac Surgery
In recent years, a growing body of research has shown that diabetes plays an important role in the development and recurrence of atrial fibrillation.
- Trial name
- NCT05374655
- Testing
- Preoperative blood glucose control
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Kun Hua
Obesity
Venous Thromboprophylaxis in Bariatric Surgery
The main aim of this study is to compare the influence of total body-weight (TBW), lean body-weight (LBW), ideal body-weight (IBW) or Body Mass Index (BMI) on peak anti-Xa levels at steady-state in bariatric surgery (BS) morbidly…
- Trial name
- OBSUD (NCT03218514)
- Testing
- Dalteparin
- Volunteers
- 118 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Perfusion Index and Cerebral NIRS Trends in Low Cardiac Output Syndrome
Can Perfusion Index and Cerebral Oxygen Saturation Trends Predict Low Cardiac Output in Pediatric Cardiovascular Surgeries
In this prospective, observational study, we aim to investigate whether routinely monitored Perfusion Index (PI) and cerebral oxygen saturation (NIRS) values in pediatric patients aged 0-6 undergoing congenital heart surgery are…
- Trial name
- NCT06759506
- Volunteers
- 40 people
- Sponsor
- Bozyaka Training and Research Hospital
Atherosclerosis
Platelet Rich Plasma Study in Lower Extremity Bypass Surgery
The use of platelet rich plasma will decrease wound infection postop.
- Trial name
- PRP (NCT00517452)
- Volunteers
- 81 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Right Ventricular Dysfunction, Right Heart Failure
Right Ventricular Pressure Waveform Monitoring in Cardiac Surgery
RV dysfunction has been associated with increased mortality in the ICU and cardiac surgical patients. Thus, early identification of RV dysfunction at less severe stages will allow for earlier intervention and potentially better…
- Conditions
- Right Ventricular Dysfunction, Right Heart Failure, Congestive Heart Failure
- Trial name
- PACEPORT (NCT04092855)
- Where
- Canada
- Volunteers
- 112 people
- Sponsor
- Montreal Heart Institute
Acute Coronary Syndrome (ACS)
Effect of Perioperative Clopidogrel Responsiveness on Ischemic Outcome in Patients With Acute Coronary Syndrome Undergoing Off-pump Coronary Artery Bypass Surgery
The whole blood Thrombelastograph (TEG®) Platelet Mapping™ assay measures clot strength, maximal amplitude (MA), reflecting maximal platelet function, and detects the reduction in platelet function, presented as percentage…
- Trial name
- NCT02184884
- Testing
- MACE after OPCAB, without MACE after OPCAB
- Where
- South Korea
- Volunteers
- 195 people
- Sponsor
- Yonsei University
Heart Failure With Reduced Ejection Fraction
Respiratory Sinus Arrhythmia (RSA) Pacing Post-CABG Surgery in Patients With HFrEF
The goal of this clinical trial is to test a new type of pacemaker in heart failure patients following a heart bypass operation.
- Trial name
- RSA-PACE (NCT06359938)
- Testing
- Atrial pacing with respiratory sinus arrhythmia (RSA) variability, Monotonic right atrial overdrive pacing
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Ceryx Medical Ltd
Hypotension Drug-Induced, Spinal Aneshtesia
Effect of Lateral Decubitus Position After Spinal Anesthesia on Hemodynamic Stability in High-Risk Geriatric Patients
Spinal anesthesia is a common and preferred anesthetic technique for lower extremity orthopedic surgery in elderly patients. However, it can cause a significant drop in blood pressure (hypotension), especially in high-risk older…
- Conditions
- Hypotension Drug-Induced, Spinal Aneshtesia, Geriatric, Orthopedic Surgery Patients
- Trial name
- NCT07597148
- Testing
- Lateral Decubitus Positioning, Immediate Supine Positioning
- Volunteers
- 70 people
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research
Coronary Artery Disease
Intravenous Fish Oil in Critically Ill Cardiac Patients
A large body of evidence has accumulated showing that n-3 PUFAs exert extensive cardiac effects. The development of commercial solutions of FO opens perspectives for therapeutic applications in patients with acute cardiac…
- Trial name
- FO-cardiac (NCT00516178)
- Testing
- Fish oil emulsion, Saline
- Where
- 2 sites in Switzerland
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Erythrocyte Transfusion, Machine Learning
Machine Learning Versus Traditional Scores in Predicting Erythrocyte Need
In this study, we compared perioperative bleeding prediction scores with our machine learning-based prediction system in predicting the need for erythrocyte suspension during cardiovascular surgery.
- Trial name
- NCT06594484
- Testing
- Ml Based Algorithm 1, Ml Based Algroithm 2, Bleeding Scores
- Where
- Turkey (Türkiye)
- Volunteers
- 430 people
- Sponsor
- Kocaeli City Hospital
Atrial Fibrillation, Thromboembolism
Impact of Left Atrial Appendage Exclusion on Short-Term Clinical Outcomes and Long-Term Stroke Incidence
Stroke is a major cause of morbidity in western society, and an infrequent complication of cardiac surgery. The majority of thromboembolic strokes arise from the left atrium, in particular the left atrial appendage.
- Conditions
- Atrial Fibrillation, Thromboembolism, Cerebrovascular Accident
- Trial name
- NCT00486915
- Testing
- Left Atrial Appendage Ligation
- Where
- Italy
- Volunteers
- 43 people
- Sponsor
- London Health Sciences Centre
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