Clinical trials: Surgery, Cardiovascular
Hypertension, Malignant, Airway Management
Using Ambu Aura-i Laryngeal Mask Airway in Cranial Surgery
the investigators hypothesize that Ambu aura-i LMA can be used safely in patients undergoing craniotomies and are effective in reducing the incidence of emergence hypertension.
- Trial name
- NCT04582227
- Testing
- Ambu aura-i LMA
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Stenoses, Aortic Valve
REPRISE China - Clinical Evaluation in China
To evaluate the safety and effectiveness of the Lotus Edge™ Valve System for transcatheter aortic valve replacement (TAVR) in symptomatic Chinese patients with calcific, severe native aortic stenosis who are considered at high…
- Trial name
- NCT03084510
- Testing
- Lotus Edge™ Valve System
- Where
- China
- Sponsor
- Boston Scientific Corporation
USE OF ARTIFICIAL INTELLIGENCE IN ANESTHESIA, PREOPERATIVE CARDIOLOGY CONSULTATION REQUIREMENT
The Predictability of the Necessity for Cardiology Consultation in Patients Scheduled for Non-Cardiac Surgery Using Artificial Intelligence Models in Preoperative Anesthesia Assessment
Structured Summary Title Predictability of Cardiology Consultation Requirement in Patients Undergoing Non-Cardiac Surgery Using Artificial Intelligence Models Background Preoperative cardiac risk assessment is essential for…
- Trial name
- NCT07395713
- Testing
- Patient scenarios were presented to different AI models (ChatGPT 4.5, ChatGPT 5, Copilot, Deepseek, Grok, Claude, Gemini Flash, Gemini Pro) with and without prompts.
- Where
- Turkey (Türkiye)
- Volunteers
- 183 people
- Sponsor
- Bursa City Hospital
Congenital Heart Defects, Heart Valve Diseases
Cardiac Operation Under Totally Endoscope and Cardiopulmonary Bypass (CPB)
Conventional cardiac operations are performed with median sternotomy, which is related to great wound, morbidities, longer duration in hospital and most significantly, cosmetic problems.
- Trial name
- CPB (NCT00921596)
- Testing
- cardiac operation with totally endoscopic method
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Xijing Hospital
Arrhythmia, Acute Kidney Injuries
This is an Observational Study That Aims to Demonstrate Postoperative Risk Factors in Pediatric Cardiac Surgery
This retrospective observational study aims to identify risk factors for postoperative complications in children undergoing cardiac surgery at a tertiary hospital in Brazil.
- Conditions
- Arrhythmia, Acute Kidney Injuries, Sepsis, Pneumopathy
- Trial name
- PEDS-CARE (NCT06985082)
- Testing
- THERE IS NOT A INTERVENTION
- Volunteers
- 310 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Hemorrhoids, Anal Fistula
Hemostatic and Analgesic Effect of Gel Foam and Gauze With Bosmin After Anal Surgery
To evaluate the hemostatic and analgesic effect of using gauze with Bosmin or Gelfoam after anal surgery.
- Trial name
- NCT05605080
- Testing
- Gelfoam, Bosmin gauze
- Where
- Taiwan
- Volunteers
- 292 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Aortic Valve Stenosis
Desflurane-induced Myocardial Protection
This study examines pharmacological preconditioning and post conditioning of desflurane by comparing cardiac troponin release in patients receiving either desflurane or propofol for the aortic valve surgery.
- Trial name
- NCT02019797
- Testing
- Desflurane
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Nobuyuki Katori
Sarcopenia, Exercise Intolerance
Prehabilitation for Cardiac Surgery in Patients With Reduced Exercise Tolerance
Among patients awaiting cardiac surgery, a significant proportion are patients with severe angina, heart failure (HF) and peripheral atherosclerosis.
- Conditions
- Sarcopenia, Exercise Intolerance, Heart Failure, Peripheral Artery Disease
- Trial name
- NCT04545268
- Testing
- Neuromuscular electrical stimulation (NMES), Transcutaneous electrical stimulation
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Research Institute for Complex Problems of Cardiovascular Diseases, Russia
Cardiac Disease
Cardiac Deformation: Correlation With Conventional Echocardiographic Hemodynamic Variables (An Intraoperative Study)
The aim of this research is to apply cardiac tissue characterization in order to assess left ventricular function in cardiac surgical patients pre and post cardiopulmonary bypass.
- Trial name
- NCT00874991
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- Weill Medical College of Cornell University
Venous Thromboembolism
Dose Ranging Study in Elective Total Hip Replacement Surgery
The primary objective is to: demonstrate the efficacy of SR123781A in the prevention of venous thromboembolism (VTE) by the demonstration of a dose-response in patients undergoing total hip replacement surgery.
- Trial name
- DRIVE (NCT00338897)
- Testing
- SR123781A
- Where
- 14 sites in Argentina, Bulgaria and 12 more
- Volunteers
- 1,090 people
- Sponsor
- Sanofi
Coronary Artery Bypass Graft Surgery Patients
Improving Outcomes and Quality of Life After CABG
The principal objective to this randomized trial is to compare the efficacy of two strategies of intra-operative hemodynamic management during cardiopulmonary bypass among patients undergoing primary elective coronary artery…
- Trial name
- NCT00256620
- Testing
- Mean arterial pressure during cardiopulmonary bypass 80 mmHg vs. customized
- Where
- United States
- Volunteers
- 412 people
- Sponsor
- Weill Medical College of Cornell University
Coronary Artery Disease
Perioperative Depression and Postoperative Arrhythmia in Elective Coronary Bypass Graft Surgery
Postoperative arrhythmias (heart irregularities) are one of the most common complications after cardiac surgery and are associated with increased morbidity and mortality.
- Trial name
- NCT00622024
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
Intracerebral Hemorrhage, Hemorrhagic Risk Conditions
Ex Vivo Reproduction of Minimally Invasive Surgery With Hematoma Lysis Using Modified Tissue Plasminogen Activator for Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) is associated with high mortality and long-term disability, and effective treatment options remain limited.
- Conditions
- Intracerebral Hemorrhage, Hemorrhagic Risk Conditions, Bleeding Disorders
- Trial name
- MIMICK-TIPITCH (NCT07411079)
- Testing
- Ex vivo exposure to modified rtPA
- Where
- France
- Volunteers
- 1,126 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Cardiac Valves, Heart Valve Diseases
Percutaneous Device Closure for Significant Paravalvular Leakage After Transcatheter or Surgical Valve Replacement
This study evaluates the effectiveness and safety of Percutaneous Device Closure for Significant Paravalvular Leakage after transcatheter or surgical valve replacement.
- Conditions
- Cardiac Valves, Heart Valve Diseases, Valvular Insufficiency
- Trial name
- PVL closure (NCT03793296)
- Testing
- Percutaneous Device Closure: Vascular plug
- Where
- South Korea
- Sponsor
- Seung-Jung Park
Coronary Artery Disease
Effect of Clopidogrel (Plavix) on Postoperative Bleeding in Patients Undergoing Coronary Artery Bypass Surgery.
Running title: Effect of Clopidogrel on Postoperative Bleeding in Patients undergoing Coronary Artery Bypass Surgery Title: Clopidogrel and bleeding in patients undergoing coronary artery bypass grafting.
- Trial name
- NCT00724880
- Testing
- Clopidogrel
- Volunteers
- 135 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Vascular Disease
Tobacco's Impact on Postoperative Complications in Acute Surgery
The purpose of the study is to see whether intensive smoking intervention on the day of operation can reduce per- and postoperative complications in patients operated for acute ischaemic disease compared to control group with no…
- Trial name
- ROC (NCT01469091)
- Testing
- Smoking intervention.
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cardiac Surgery, Enhanced Recovery After Surgery
The Application of Enhanced Recovery After Surgery (ERAS) for Cardiovascular Surgery in Adult
Among adults, patients undergoing elective extracorporeal circulation for cardiac surgery are included in the ERAS strategy intervention plan, which mainly includes preoperative education, preoperative oral intake of…
- Trial name
- NCT05914090
- Testing
- ERAS
- Where
- 2 sites in China
- Volunteers
- 3,600 people
- Sponsor
- Yan Fuxia
Systemic Inflammatory Response Syndrome (SIRS), Postoperative Vasodilation Syndrome
Prediction of Inflammatory Response and Hypotensive Syndrome After Cardiac Surgery by Preoperative Copeptin Level
The purpose of this study is to find a preoperative biomarker before cardiac surgery with cardiopulmonary bypass related to severe postoperative inflammatory response and circulatory complications.
- Conditions
- Systemic Inflammatory Response Syndrome (SIRS), Postoperative Vasodilation Syndrome, Stress Response, Cardiac Surgery Prognosis
- Trial name
- MicorSIRS (NCT03288610)
- Testing
- Preoperative copeptin level
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Surgery, Obesity Associated Disorder
Bariatric Surgery on obesity-and Diabetes-associated Abnormalities of Hemostasis, Inflammation and Vascular Function.
The goal of this prospective cohort study is to examine circulating biomarkers before and after weight loss in patients with obesity, with or without concomitant diabetes, undergoing bariatric surgery.
- Conditions
- Surgery, Obesity Associated Disorder, Coagulation Disorder, Diabetes Complications
- Trial name
- FIBRINO (NCT06071559)
- Testing
- Laparoscopic Roux-en-y gastric bypass
- Volunteers
- 61 people
- Sponsor
- Ersta Diakoni
Hypotension During Surgery
Goal-directed Fluid Therapy During Deep Inferior Epigastric Perforator (DIEP) Free Flap Breast Reconstruction
Adequate free flap perfusion during Deep Inferior Epigastric Perforator (DIEP) flap breast reconstruction surgery requires maintaining blood pressure above 100 mmHg and avoiding excessive fluid administration.
- Trial name
- GDFT DIEP-flap (NCT06080178)
- Testing
- Plasma-lyte (static group), Norepinephrine (static group), Plasma-lyte (dynamic group)
- Where
- Belgium
- Volunteers
- 41 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
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