Clinical trials: Surgery, Dental
Pain
A Study of Ibuprofen (IBU) 250mg/APAP 500mg In The Treatment Of Post-Surgical Dental Pain
This study is being conducted to determine the overall analgesic efficacy and safety of a fixed-dose ibuprofen 250 mg / acetaminophen 500 mg formulation compared to placebo in subjects who are experiencing post operative pain…
- Trial name
- NCT02837952
- Testing
- FDC IBU/APAP 250 mg/500 mg
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Pfizer
Dental Implant, Tooth Loss
Flap Vs Flapless Technique for Delayed Implant Placement in the Maxillary Esthetic Zone
This randomized comparative clinical trial aims to evaluate the clinical, radiographic, and esthetic outcomes of flap versus flapless techniques for delayed dental implant placement in the maxillary esthetic zone.
- Conditions
- Dental Implant, Tooth Loss, Partial Edentulism, Maxillary Tooth Loss
- Trial name
- NCT07654452
- Testing
- Flap Implant Placement, Flapless Implant Placement
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Pain, Postoperative
Safety and Efficacy of Intranasal Ketamine for the Treatment of Postoperative Dental Pain
Once patients' postoperative pain intensity reaches a moderate-to-severe level, they are randomized to receive intranasal ketamine or placebo.
- Trial name
- NCT00488787
- Testing
- intranasal ketamine
- Volunteers
- 40 people
- Sponsor
- Javelin Pharmaceuticals
Surgery, Computer-Assisted, Dental Implants
Dynamic Navigation System in Implantology
This study consists in a randomized controlled trial which objective is to assess the accuracy of a dynamic navigation system in dental implant placement in partially edentulous patients compared with the conventional freehand…
- Trial name
- NCT04344808
- Testing
- Dynamic navigation system, Freehand implant placement
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Dental Implant Surgical Techniques, Diabetes Mellitus
Effect of Diabetes on Short İmplants in One- and Two-Stage Surgeries
The goal of this clinical trial is to compare one- and two-stage techniques for short implant surgery in diabetes. The main questions it aims to answer are: Is one-stage short implant surgery at risk of implant osseointegration…
- Conditions
- Dental Implant Surgical Techniques, Diabetes Mellitus, Short Dental Implants
- Trial name
- NCT06243276
- Testing
- One stage implant surgery, Two stage implant surgery
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Erzincan University
Dental Anxiety, Impacted Mandibular Third Molar
Effects of Virtual Reality Content on Anxiety During Third Molar Surgery
This randomized controlled study evaluated whether the content of an immersive virtual reality environment influenced anxiety in adults undergoing surgical removal of an impacted mandibular third molar.
- Trial name
- NCT07819123
- Testing
- Nature-Based Virtual Reality, Art-Gallery Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Recep Tayyip Erdogan University
Dental Implant, Bone Resorption
Randomized Clinical Study Comparing Two Guided Surgery Techniques for Free-end Implant Placement
This is a randomized multicenter clinical study that compares two static guided surgery techniques in free-end partial edentulism.
- Trial name
- NCT06764654
- Testing
- Dental implant placement
- Where
- 2 sites in Spain
- Volunteers
- 40 people
- Sponsor
- Aula Dental Avanzada
Postoperative Dental Pain
A Study to Learn How Well a Single Dose of the Study Treatment Naproxen Sodium and Caffeine Combined in One Tablet (Fixed-dose Combination) Works to Relieve Pain After Dental Surgeries Compared to the Single Ingredients and to Placebo
Researchers are looking for a better way to relieve pain in people, such as after dental surgery. Participants in this study, have had 3 or 4 third molars (cheek teeth) removed and subsequently have moderate to severe tooth pain.
- Trial name
- NCT05485805
- Testing
- Naproxen sodium and caffeine (BAY2880376), Naproxen sodium (Aleve), Caffeine
- Where
- United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- Bayer
Tooth Loss, Partial-edentulism
Effect of Fixture Thread Depth on Accuracy of Immediate Implant Placement Using Dynamic Navigation
The goal of this clinical trial is to compare the placement accuracy in immediately placed implants using dynamic navigation between deep-threaded and regular-threaded implants in partially edentulous patients.
- Trial name
- NCT06056388
- Testing
- Straumann BLX implant, Straumann BLT implant
- Volunteers
- 30 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Pain, Postoperative
Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia
The purpose of this study is to investigate the effectiveness of various oral analgesic regimens in minimizing post-operative pain and discomfort in young children following dental rehabilitation under general anesthesia (DRGA).
- Trial name
- NCT06757075
- Testing
- Ibuprofen, Acetominophen
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Boston University
Jaw, Edentulous
Randomized Study For Minimally Invasive Splinted Implants
The purpose of this study was to evaluate the effect of a integrated system for inserting two splinted minimally-invasive implants, to retain mandibular over dentures, on the quality of life of edentulous patients.
- Trial name
- NCT02107612
- Testing
- Integrated system to insert two splinted (bar) mini dental implants for mandibular overdenture, Denture
- Where
- Chile
- Volunteers
- 43 people
- Sponsor
- University of Concepcion, Chile
Dental Caries
The Incidence of IV Fluid Over-administration in Pediatric Dental Surgeries When Infusion Pumps Are Employed
A prospective, analyst-blinded, randomized control trial to assess the incidence of intravenous (IV) fluid over-administration in the setting of pediatric dental surgeries.
- Trial name
- NCT03312452
- Testing
- Hospira plum pump, Gravity drip device
- Where
- Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Dental Implantation, Postoperative Pain
Patient-reported Outcome Measures Comparing Static Computer-aided Implant Surgery and Conventional Implant Surgery
The aim of this randomized controlled trial was to compare PROMs in patients receiving single tooth replacement in posterior sites by s-CAIS and CIS.
- Conditions
- Dental Implantation, Postoperative Pain, Computer-assisted Surgery, Patient Outcome Assessment
- Trial name
- NCT04950491
- Testing
- Modified Dental Anxiety Score (MDAS) questionnaire, Pain questionnaire, Oral Health-Related Quality of Life (OHRQoL) questionnaire
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Acute Pain
Preventive Treatment of Pain After Dental Implant Surgery
The objective of this prospective randomized double-blind study was to evaluate the effects of the preoperative administration of dexketoprofen trometamol (DKT) on the pain perceived by patients after oral surgery for implant…
- Trial name
- UMU (NCT03107338)
- Testing
- DEXKETOPROFEN TROMETAMOL
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Dental Pain, Surgery, Dental
Dental Pain (Following Third Molar Tooth Extraction) Study
The purpose of this study is to evaluate the effectiveness of GW406381 (a COX-2 inhibitor) in treating the signs and symptoms of dental pain following third molar tooth extraction.
- Trial name
- NCT00114049
- Testing
- GW406381
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- GlaxoSmithKline
Dental Anxiety
Effects of Consent Methods Performed According to Intelligence Types on Anxiety Associated with Third Molar Surgery
The aim of this study is to investigate the effect of information provided in accordance with intelligence type on anxiety associated with wisdom tooth surgery.
- Trial name
- NCT04613947
- Testing
- Informed consent, Third molar surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ordu University
Dental Implant
Accuracy of Dental Implant Placement Using a Collaborative Surgery Robot
For free hand dental implant placement, a key difficulty is to accurately control the position. Improving precision of dental implant placement is considered important for safety and efficacy of tooth replacement with dental…
- Trial name
- NCT05919862
- Testing
- Robot system, Freehand surgery
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Oral Surgery, Tooth Extraction
Assessment of DAFILON® Suture Material in Oral Surgery (Mucosal Sutures)
In this non-interventional study (NIS) a polyamide non-absorbable suture (Dafilon) will be evaluated for oral surgery (mucosal closure after e.g. wisdom teeth extraction, implant surgery, etc.) in adult patients
- Conditions
- Oral Surgery, Tooth Extraction, Dental Implants
- Trial name
- MUCODA (NCT04390620)
- Testing
- Mucosal Closure
- Where
- 2 sites in Germany, Spain
- Volunteers
- 105 people
- Sponsor
- Aesculap AG
Root Caries
Evaluation of Corrective Surgery Versus Dental Implants in Compromised Upper Molars
This study seeks to assess the clinical, radiographic, and patient-reported outcomes of root amputation versus implant over a 12 months period, generating robust evidence to guide clinical decision-making and enhance patient care.
- Trial name
- NCT07608497
- Testing
- root amputation
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Bone Augmentation
Evaluation of the Safety and Performance of the Neobone®: A Prospective Observational Study in Dental Area
This study aims to collect real-world clinical data to gather information on the performance and safety of the Neobone® when used according to its intended purpose and current clinical applications.
- Trial name
- NeoDent01 (NCT07179497)
- Where
- Portugal
- Volunteers
- 66 people
- Sponsor
- Bioceramed