Clinical trials: Surgery, Dental
Moderate Pain, Severe Pain
Efficacy and Safety of DIT112 in the Treatment of Moderate to Severe Pain After Dental Surgery for the Extraction of Impacted Third Molars
The purpose of this study is to evaluate the efficacy and safety of DIT112 in adolescents and adults with acute pain after dental surgery for the extraction of impacted third molars.
- Trial name
- ALIV (NCT06237231)
- Testing
- DIT112, DIPYRONE, TRAMADOL
- Volunteers
- 252 people
- Sponsor
- EMS
Excessive Gingival Display, Gingival Diseases
Botulinum Toxin Type A Versus Cross-Linked Hyaluronic Acid Filler Myomodulation for Non-Surgical Management of Excessive Gingival Display
This randomized controlled trial compared the clinical efficacy and patient satisfaction of two non-surgical treatments for excessive gingival display (gummy smile): botulinum toxin type A (BTX-A) and cross-linked hyaluronic acid…
- Conditions
- Excessive Gingival Display, Gingival Diseases, Gummy Smile, Esthetics, Dental
- Trial name
- NCT07715331
- Testing
- Botulinum Toxin Type A (Refinex®), Cross-Linked Hyaluronic Acid Filler (Juvéderm Voluma® with Lidocaine)
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Tooth, Impacted, Teeth Impact
Performance of Safety of SILKAM® Suture Material in Oral Surgery
Assessment of SILKAM® suture material in mucosal closure in oral surgery (mucosal sutures). A prospective, monocentric, single arm observational study.
- Conditions
- Tooth, Impacted, Teeth Impact, Tooth Impaction, Mucosal Wound
- Trial name
- SILKOS (NCT05296902)
- Testing
- Mucosal Closure
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Aesculap AG
Post-surgical Dental Pain
Post-operative Dental Pain Study Comparing Analgesic Efficacy
GlaxoSmithKline will be conducting this trial to compare analgesics efficacy of paracetamol 1000mg vs 500mg . The post-surgical dental pain model will be used to evaluate the analgesic efficacy of paracetamol.
- Trial name
- NCT01082081
- Testing
- Paracetamol 1000 mg, Paracetamol 500 mg
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- GlaxoSmithKline
Periodontitis
L-PRF Plus Non Surgical Periodontal Treatment
Abstract: Background: Leucocyte and Platelet-Rich Fibrin (L-PRF) has shown to promote regenerative processes, even reporting antibacterial effect.
- Trial name
- NCT04520438
- Testing
- Leukocyte and platelet rich fibrin, Non-Surgical Periodontal treatment
- Where
- Chile
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Pain
A Dental Pain Study to Test the Effectiveness of a New Pain Reliever Medicine
To assess the safety and effectiveness one dose of a new pain reliever medicine (JNJ-10450232 at either the 250 or 1000 mg strength) compared with placebo (sugar pill) or acetaminophen 1000 mg after surgical removal of third…
- Trial name
- NCT02209181
- Testing
- JNJ-10450232 / Not yet marketed, acetaminophen / Tylenol
- Where
- United States
- Volunteers
- 269 people
- Sponsor
- McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.
Gingival Biotype, Gingival Phenotype
Early Effects of Orthognathic Surgery on Periodontal Phenotype: A 6-Month Prospective Clinical and Radiographic Evaluation
The goal of this observational study is to learn how the health and thickness of the gums and supporting bone around the teeth change over 6 months in adults having jaw surgery to correct the bite.
- Conditions
- Gingival Biotype, Gingival Phenotype, Buccal Bone Thickness, Recession, Gingival
- Trial name
- NCT07349056
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Trakya University
Dental Implant
Computer Guided Versus Freehand Dental Implant Surgery
This study's goal is to evaluate the efficacy of traditional rehabilitation with freehand implant implantation of partly or totally edentulous patients utilizing flapless or mini-flap procedures vs.
- Trial name
- dental implant (NCT06204692)
- Testing
- dental implant
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- October 6 University
Endodontic Disease, Endodontic Re-treatment Failure
The 3-Dimensional Printed Guide in Endodontic Microsurgery
In recent years, there was a great interest in employing the surgical guide in dentistry due to the development occurred in the 3D printing which became available widely.
- Trial name
- NCT05283252
- Testing
- 3-D printed Guide, Conventional Endodontic Micro-Surgery
- Where
- Syria
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Damascus University
Dental Implants, Wound Healing
Effect of Different Suture Techniques on Early Healing of Peri-implant Soft Tissue
The purposes of this study are to compare the blood perfusion and early healing of horizontal mattress suture with vertical mattress sutures following open-flap implant surgery.
- Conditions
- Dental Implants, Wound Healing, Sutures
- Trial name
- NCT05289635
- Testing
- different suture types
- Volunteers
- 20 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Nasal Intubation, Dental Surgery
Does Altering Magill Forceps Affect Nasal Intubation Time
The purpose of this study is to see whether altering the angle of the Magill forceps by 45 degrees will affect nasal intubation time in pediatric dental surgery patients.
- Conditions
- Nasal Intubation, Dental Surgery, Pediatrics
- Trial name
- NCT02109211
- Testing
- Intubation with Magill forceps, Intubation with altered Magill forceps
- Where
- Canada
- Volunteers
- 133 people
- Sponsor
- University of Saskatchewan
Pain
Study Evaluating A Novel Ibuprofen Formulation In The Treatment Of Dental Pain
This study will compare the pain relieving effect of a single-dose of a novel ibuprofen formulation to placebo and two formulations of standard ibuprofen in the treatment of post-surgical dental pain following "wisdom" tooth…
- Trial name
- NCT01098747
- Testing
- Novel Ibuprofen, Standard Ibuprofen
- Volunteers
- 335 people
- Sponsor
- Pfizer
Post-operative Pain
Ketamine in Post-operative Dental Pain and Recovery
Low dose sub-anaesthetic dose of ketamine has been shown to reduce postoperative pain and analgesic consumption. However, due to the heterogeneous results, the standard dosing regimen has not been available.
- Trial name
- NCT02021240
- Testing
- Ketamine, Dexamethasone, Normal Saline
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- The University of Hong Kong
Endodontic Disease
Effect of Platelet-Rich Plasma Biomembrane on Enhancing Bone Regeneration Following Endodontic Surgery
This study was conducted to evaluate clinical and radiographical outcome of using a standardized platelet-rich plasma (PRP) biomembrane following endodontic surgery and its correlation with the growth factors content in this…
- Trial name
- NCT04109417
- Testing
- osteotomy filled with PRP-gel and covered with PRP-biomembrane, osteotomy site following the surgical intervention was left empty
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Alexandria University
Maxillary Hypoplasia
Orthodontic Retention on the Maxillary Stability After SARME Using Laser Scanner
The objective of this study was to evaluate the effect of the orthodontic retainer on transverse maxillary dental and skeletal stability after SARME.
- Trial name
- NCT01770782
- Testing
- Surgically Assisted Rapid Maxillary Expansion (SARME), Laser Scanner
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Max Domingues Pereira
Endodontically Treated Teeth
Deep Margin Elevation Vs Crown Lengthening
The present clinical trial will be conducted to reject or accept the null hypothesis that in endodontically treated posterior teeth with deeply located proximal margins, will the Deep Margin Elevation will have better results…
- Trial name
- NCT05381298
- Testing
- Deep Margin Elevation using resin composite, Surgical Crown Lengthening
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Surgically Repaired Unilateral Cleft Lip and Palate
Evaluation of Arch Dimensions of Children With Surgically Repaired Unilateral Cleft Lip and Palate
The aim of the study is to assess arch dimensions among children with surgically repaired unilateral cleft lip and palate.
- Trial name
- NCT03219021
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Menna Allah Mohammed Awad
Bleeding, Pain
Colibricare Efficacy on Oral Surgical Procedures/Extraction Wound and Gingiva Retraction
In this randomized, three-arm trial, 120 patients undergoing wisdoms' extractions were assigned to control (gauze pressure application), commercial sponge, or Coli-sorb® groups.
- Trial name
- NCT07638930
- Testing
- wisdoms' surgical extractions
- Where
- Egypt
- Volunteers
- 124 people
- Sponsor
- Cairo University
Odontogenic Cysts, Keratocysts of the Jaw
Decompression of Odontogenic Cysts
The aim of this case-control study is to evaluate the effects of decompression of cystic jaw lesions by means of comparing pre- and post-decompression histologic findings.
- Conditions
- Odontogenic Cysts, Keratocysts of the Jaw, Cysts Dental, Pathology
- Trial name
- NCT06536907
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Dental Caries
Evaluation of the Chemo-mechanical Caries Removal Agent (BRIX3000®) in Primary Molars
Dental caries is one of the most prevalent chronic diseases in people worldwide. Traditional clinical treatment of dental decay has developed on the basis of the removal of carious tissues with high-speed handpieces and…
- Trial name
- NCT05427591
- Testing
- The chemomechanical caries removal agent "BRIX3000®" in group (1A), The traditional surgical treatment in group (1C), The chemomechanical caries removal agent "Carie-CareTM" in group (2B)
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University