Clinical trials: Surgery, Intensive Care
Ventilator Associated Events
Evaluation of the Review of Automated Ventilator Data's Effect on the Incidence of Ventilator Associated Events in a Medical Surgical Intensive Care Unit
This study will be a retrospective, observational analysis study of ventilator patients in the Medical Surgical Intensive Care unit being monitored via automated near real-time ventilator analytical software.
- Trial name
- NCT03850340
- Volunteers
- 100 people
- Sponsor
- St. Joseph's/Candler Health System
Critical Care
Effect of Glutamine and Vitamin C on Interleukin-6 and Clinical Outcomes in Surgical Intensive Care Unit Patients
Background \& Aims. Glutamine is a conditional essential amino acid that was found in reduced plasma amount in Intensive Care Unit (ICU) patients.
- Trial name
- NCT03166956
- Testing
- Glutamine and vitamin C enteral supplement
- Volunteers
- 41 people
- Sponsor
- Chung Shan Medical University
Sarcopenia, Muscle Weakness
Effects of Mobility Dose in Surgical Intensive Care Unit Patients
The primary aim of this study is to assess if the mobility dose that patients receive in the surgical intensive care unit (SICU) predicts adverse discharge disposition (primary endpoint), and muscle wasting diagnosed by bedside…
- Conditions
- Sarcopenia, Muscle Weakness, Critical Illness
- Trial name
- MQS (NCT03196960)
- Where
- 3 sites in United States, Germany and 1 more
- Volunteers
- 150 people
- Sponsor
- Massachusetts General Hospital
Critical Illness, Postoperative Complications
General Surgery Patients at the Intensive Care Unit
Introduction: high-risk surgical patients in the intensive care unit (ICU) are a unique population that has yet to be carefully monitored.
- Trial name
- TraViII (NCT06731296)
- Testing
- Presence of a risk factor
- Where
- 2 sites in Colombia
- Volunteers
- 1,000 people
- Sponsor
- Hospital Departamental de Villavicencio
Intensive Care Units, Neonatal, Misadventures to Patients During Surgical and Medical Care
SEPREVEN: a Stepped-wedge Randomised Controlled Trial
Adverse events are frequent in Neonatal Intensive Care Units' (NICU) patients and account for a high morbidity and mortality. Possible severe adverse events are central line associated bloodstream infections (CLABSI), ventilator…
- Conditions
- Intensive Care Units, Neonatal, Misadventures to Patients During Surgical and Medical Care, Catheter-related Bloodstream Infection (CRBSI) Nos, Quality of Healthcare
- Trial name
- SEPREVEN (NCT02598609)
- Testing
- Education program for NICU caregivers
- Where
- 12 sites in France
- Volunteers
- 8,000 people
- Sponsor
- Dr Caeymaex Laurence
Gastric Residual Volume, Abdominal Distension
Abdominal Massage for Gastric Residual Volume in Surgical Patients
This randomized controlled trial aimed to evaluate the effect of abdominal massage on gastric residual volume (GRV) and abdominal distension in surgical intensive care patients receiving enteral nutrition.
- Conditions
- Gastric Residual Volume, Abdominal Distension, Enteral Nutrition, Massage Therapy
- Trial name
- NCT07018414
- Testing
- Abdominal Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Marmara University
Delirium
Environmental Intervention on Delirious Patients
The implementation of environmental intervention program reduced the duration of delirium and length of stay at the ICU in critically-ill surgical patients.
- Trial name
- NCT04042649
- Testing
- environmental intervention
- Where
- South Korea
- Volunteers
- 192 people
- Sponsor
- Asan Medical Center
Cerebral Ischemia
Reversing Cerebral Oxygen Desaturations Greater That 10% of Baseline Values Using NIRS in the ICU
Study objectives: The main objective of this study is to determine the feasibility of implementing measures in the intensive care unit (ICU), based on a physiological algorithm, to reverse decreases in cerebral oxygen saturation…
- Trial name
- NIRS-ICU (NCT01875055)
- Testing
- NIRS and Algorithm, NIRS derived cerebral oximetry
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- University of Manitoba
Intensive Care Unit Delirium, Cardiac Surgery
Delirium After Cardiac Surgery in Intensive Care Units
STUDY SUMMARY STUDY DESIGN The study will be conducted over twelve months in the Cardiac Intensive Care Unit (ICU) at Hammersmith Hospital, Imperial College Healthcare NHS Trust (ICHT).
- Conditions
- Intensive Care Unit Delirium, Cardiac Surgery, Post Operative Delirium
- Trial name
- DaCsi-ICU (NCT06355570)
- Testing
- Personal Pictures, Family Videos, Family Videos - Intervention as required
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College Healthcare NHS Trust
Suspected Delirium After Elective or Emergency Heart Surgery, CAM-ICU Diagnosed Delirium
Evaluation if Physostigmine Reduces Symptoms in Patients Who Has Developed a Delirium in Intensive Care After a Surgery
Evaluation if physostigmine reduces symptoms in patients who has developed a delirium in Intensive care after a surgery
- Trial name
- NCT02216266
- Testing
- Physostigmine, Sodium Chloride solution
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- PD Dr. Bertram Scheller
Chlorhexidine, Hospital-Acquired Infection
Chlorhexidine Bathing to Prevent Hospital-acquired Infections: the CLEANS Study
Hospital-acquired infections (HAI) have been shown to increase length of hospital stay and mortality. Infections acquired during a hospital stay have been shown to be preventable.
- Conditions
- Chlorhexidine, Hospital-Acquired Infection, Surgery, Intensive Care Unit
- Trial name
- NCT05142969
- Testing
- 2% Chlorhexidine bathing
- Where
- China
- Volunteers
- 247 people
- Sponsor
- Shanghai Zhongshan Hospital
Postoperative Respiratory Failure, Abdominal Surgery
Mechanical Power for Ventilatory Settings in Operating Room
Postoperative respiratory failure (PRF) is a dreaded complication that imposes a significant burden through unplanned admission to the ICU, post discharge disability and mortality.
- Conditions
- Postoperative Respiratory Failure, Abdominal Surgery, Postoperative Pulmonary Complications, Morality
- Trial name
- IMPROVEIII (NCT07620132)
- Testing
- Mechanical power-guided ventilatory strategy, Standard fixed ventilatory settings
- Volunteers
- 490 people
- Sponsor
- University Hospital, Montpellier
Duration of Hospitalization in Intensive Care Unit
Evaluation of the Effectiveness of the Administration of Local Anesthetics Via Two Catheters Placed During Surgery, and Study of the Benefits on Respiratory Function and Therefore on Recovery Time
Currently intravenous analgesics are used for postoperative analgesia. But the analgesia of these products is tempered by their adverse effects (sedation, confusion, nausea or vomiting, delayed transit, urinary retention and…
- Trial name
- PARALSTER (NCT06463899)
- Testing
- multi-perforated catheter, Classic procedure
- Where
- France
- Volunteers
- 114 people
- Sponsor
- CHU de Reims
Sleep Disorders, Delirium
Evaluation of Risk Factors of Sleep Quality in Intensive Care Unit
The aim of this study was to investigate the relationship between sleep disturbances and delirium in surgical ICU patients. The study set up to test the hypothesis that the occurrence of delirium is associated to the alteration…
- Trial name
- NCT00507481
- Where
- 2 sites in Italy
- Sponsor
- University of Turin, Italy
Analgesia, Sedation
Surgical Stress Index as a Tool for Monitoring Analgesia and/or Sedation in Critically Ill Patients
The hypothesis of the study is: Does the Surgical Stress Index (SSI) correlate with the Behavioral Pain Scale (BPS), the Ramsay Sedation Scale (RSS)and/or the Behavioral Pain Scale(BPV) and can therefore be used to monitor the…
- Conditions
- Analgesia, Sedation, Mechanical Ventilation, Pain
- Trial name
- NCT00789412
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Schleswig-Holstein
Diet, Healthy, Food
The PASTDUe Nutrition Ecosystem Project (PASTDUe)
This is a research study to determine if a particular method of providing nutrition improves the clinical outcomes of patients in the intensive care unit (ICU) who have undergone abdominal surgery and would require nutrition…
- Conditions
- Diet, Healthy, Food, Nutrition, Intensive Care
- Trial name
- PASTDUe (NCT05127109)
- Testing
- Nutrition Ecosystem pathway, Comparator
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Duke University
Continuous Glucose Measurement
A Comparative Study to Evaluate the Accuracy and Safety of the GlySure Continuous Intravascular Glucose Monitoring System Versus Intermittent Blood Glucose Monitoring
The purpose of this study is to evaluate the system performance of the GlySure Continuous Glucose Monitoring (CGM) system in patients admitted to the Surgical Intensive Care Unit.
- Trial name
- NCT01942902
- Testing
- Continuous Glucose Monitoring System
- Where
- 2 sites in India
- Volunteers
- 38 people
- Sponsor
- GlySure
Sepsis, Cancer, Heart Attack, Heart Failure, Abdominal Surgery, Trauma, Diabetes, Lung Disease, Gynaecology, Fertility, Cardiac Surgery,
Medical Record Study on Adverse Events Requiring a Higher Level of Care in Flemish Hospitals
An adverse event (AE) is defined as unintended injury or complication, which results in disability, death or prolongation of hospital stay, and is caused by healthcare management (including omissions) rather than the patient's…
- Trial name
- NCT02044718
- Where
- Belgium
- Volunteers
- 878 people
- Sponsor
- Hasselt University
Pleural Effusion, Pneumothorax
Thoracic Drains in Intensive Care Units: Comparison of Seldinger and Surgical Methods
This prospective randomized multicenter study is intended to investigate tolerance and effectiveness of thoracic drainage conducted by Seldinger technique with small drains, or by a surgical-like technique with large armed…
- Conditions
- Pleural Effusion, Pneumothorax, Hemothorax
- Trial name
- DrainICU (NCT04438317)
- Testing
- Pleural drainage procedure with Seldinger procedure, Pleural drainage procedure with surgical-like technique
- Where
- France
- Volunteers
- 227 people
- Sponsor
- University Hospital, Clermont-Ferrand
Premature Infant Sleep
Sleep Organization in Premature Infants With Feeding Difficulties
Babies born too soon, premature babies, can have complications following birth because their systems are immature. Hospitals help prevent deformities and delays in motor development by using therapeutic positioning to provide…
- Trial name
- NCT01946308
- Testing
- Conformational positioning system
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati