Clinical trials: Surgery, Intensive Care
Postoperative Hypotension
Hypotension Prediction During Cardiac Surgery Postoperative Period
The goal of this observational study is to learn about the performance of a new index for hypotension prediction during the immediate postoperative period of cardiac surgery patients in the intensive care unit.
- Trial name
- HPI-CCV (NCT05840432)
- Testing
- Postoperative hypotension prediction index
- Where
- Spain
- Volunteers
- 41 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Surgical Procedure, Unspecified
VRES Study in Two Phases to Monitor Cardiac Surgical Patients Following Discharge From ICU
Failure to recognise deterioration early is a major cause of preventable deaths amongst hospital patients. The investigators wish to study whether continuous monitoring of 'vital signs' (pulse rate, breathing rate, and blood…
- Trial name
- VRES (NCT02427828)
- Testing
- Visensia Respiration Rate Estimation Service (VRES)
- Where
- United Kingdom
- Volunteers
- 208 people
- Sponsor
- OBS Medical Ltd
Cardiac Surgery Patients
Physiotherapy in Patients in a Cardiac Intensive Care Unit
Background. Cardiovascular diseases are a major cause of morbidity and mortality. The management of these patients requires multidisciplinary therapeutic approaches.
- Trial name
- NCT06402903
- Testing
- Observation
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Patients Are Recruited From One Thoracic and Cardiac Surgery ICU
Study of Safety and Efficacy on Neuromyopathy of Early Standing With the Assistance of Tilt Table in Critically Patients
Critically ill patients frequently develop muscle weakness due to critical illness-related acute neuropathy and/or myopathy. This disorder is associated with difficulties in weaning from mechanical ventilation, prolonged…
- Trial name
- TILT (NCT02047617)
- Testing
- the standard physiotherapy group, standing table group
- Where
- France
- Volunteers
- 145 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Cardiac Surgery Intensive Care Treatment, Delayed Recovery From Anaesthesia
Role of Levothyroxine Supplementation in Delayed Recovery Following Cardiac Surgery
Research indicates that hypothyroidism decreases heart contractility, reduces stroke volume and rate, affects the vascular endothelium, and increases the risk of atherosclerosis, systemic vascular resistance, hypertension…
- Conditions
- Cardiac Surgery Intensive Care Treatment, Delayed Recovery From Anaesthesia, Euthyroid Sick Syndrome, Cardiac Surgery Requiring Cardiopulmonary Bypass
- Trial name
- L-Thyroxine (NCT06660823)
- Testing
- L-thyroxine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Sleep Quality, Intensive Care (ICU)
Predictors of Sleep Quality in Patients Undergoing Open-Heart Surgery
Sleep quality is a complex and multidimensional phenomenon shaped by the interaction of patient characteristics, symptom burden, and environmental factors specific to the intensive care unit environment.
- Conditions
- Sleep Quality, Intensive Care (ICU), Nursing Care
- Trial name
- NCT07755280
- Where
- Turkey (Türkiye)
- Volunteers
- 157 people
- Sponsor
- Aydin Adnan Menderes University
Pain Management, Critical Illness
Evaluation of Fentanyl Transdermal Patch Absorption in Hemodynamically Unstable ICU Patients.
This study investigates how well fentanyl is absorbed through the skin when delivered via a transdermal patch in critically ill surgical ICU patients.
- Trial name
- NCT06966869
- Testing
- Transdermal fentanyl patch
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Craniectomy, Sugammadex
Comparison of the Effects of Sugammadex and Neostigmine on Early Extubation, Intensive Care Unit Admission and Length of Stay, and Hospital Costs in Adult Cranial Surgery
The aim of this study was to retrospectively investigate the effects of sugammadex or neostigmine, which are routinely used after the completion of surgery to antagonize (reverse) neuromuscular blockade in adult patients…
- Conditions
- Craniectomy, Sugammadex, Extubation, Recovery After Neuromuscular Block
- Trial name
- NCT06987357
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Head Trauma, Polytrauma
Comparative Study for the Validity of Various Severity Scoring System
Scoring systems for use in intensive care unit (ICU) patients have been introduced and developed over the last 30 years. They allow an assessment of the severity of disease and provide an estimate of in-hospital mortality
- Conditions
- Head Trauma, Polytrauma, Pre-Eclampsia, Sepsis
- Trial name
- NCT04683094
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Aswan University Hospital
Controlled Hypotension for Nasal Surgeries
Effect of Hypotensive Anesthesia on the Perfusion Index
Controlled hypotension has been used as a mean of reducing intraoperative blood loss and better visualization of the surgical field in nasal surgeries.
- Trial name
- NCT03059316
- Testing
- Massimo device, Nitroglycerin drug, Labetalol
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Thoracic Surgery, Cardiac Surgery
Comparison of Two Potassium Targets Within the Normal Range in Intensive Care Patients
Rationale: It is well known that distinctly abnormal blood potassium values can cause serious complications such as cardiac arrhythmias.
- Conditions
- Thoracic Surgery, Cardiac Surgery, Critically Ill
- Trial name
- GRIP-COMPASS (NCT01085071)
- Testing
- Potassium Chloride
- Where
- Netherlands
- Volunteers
- 1,225 people
- Sponsor
- University Medical Center Groningen
Muscle Weakness, Renal Failure
Predictors of Respiratory Failure Following Extubation in the SICU
Respiratory failure following extubation causes significant morbidity and increases mortality in teh surgical intensive care unit (SICU). However the causes of respiratory failure following extubation remain poorly understood.
- Conditions
- Muscle Weakness, Renal Failure, Respiratory Comorbidities
- Trial name
- NCT01967056
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- Massachusetts General Hospital
Acute Kidney Injury, Critical Illness
Renal Resistive Index as a Predictor of Acute Renal Impairment in High-risk Patients
To study the ability of RRI, measured by bedside Doppler ultrasound, in detecting acute kidney injury in high-risk patients admitted to surgical intensive care unit, Aswan university hospital, compared with renal biomarkers and…
- Trial name
- NCT06386796
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Aswan University
Neoplasms, Musculoskeletal Diseases
Therapy Study of Automated Protocolized vs. Physician-Directed Non-Protocolized Weaning
The purpose of this study was to determine whether computer-driven protocolized weaning is superior to physician-directed non-protocolized weaning in over-24-hours-ventilated surgical intensive care unit (ICU) patients.
- Conditions
- Neoplasms, Musculoskeletal Diseases, Digestive System Diseases, Respiratory Tract Diseases
- Trial name
- NCT00606788
- Testing
- SmartCare/PS (Automated Weaning), Conventional weaning
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Luebeck
PATİENT CARE, Intensive Care Unit
Surgical ICU Nurses' Attitudes on End-of-Life Care
This study aims to explore the attitudes and behaviors of nurses working in surgical intensive care units (ICUs) towards end-of-life care, alongside identifying the barriers they face in providing such care.
- Trial name
- NCT06285305
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Kilis 7 Aralik University
Insertion of a Nasogastric Tube, Intubated Patient
Verification of Correct Positioning of a Gastric Tube by Ultrasonography
There are several ways to verify the correct positioning of a gastric tube. Radiography is considered the reference method. The use of ultrasonography could diminish the number of radiographies necessary.
- Conditions
- Insertion of a Nasogastric Tube, Intubated Patient, Patients Hospitalized in the Surgery Intensive Care Unit
- Trial name
- SNG echo (NCT02866123)
- Testing
- ultrasonography, pulmonary radiography
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Pneumonia
Nebulized Amikacin Versus Intravenous Amikacin in the Treatment of Nosocomial Pneumonia
The investigator's goal in this study is to evaluate the efficacy and safety of nebulized amikacin versus intravenous amikacin in patients with hospital and ventilator acquired pneumonia in surgical patients admitted to the…
- Trial name
- NCT02728518
- Testing
- Nebulized Amikacin, Intravenous Amikacin
- Volunteers
- 133 people
- Sponsor
- National Heart Institute, Egypt
Serious Injury, Communication
A Communication Tool to Improve Communication in the ICU
The purpose of this study is to test the effectiveness of the Best Case/Worst Case-ICU communication tool on quality of communication, clinician moral distress, and ICU length of stay for older adults with serious traumatic…
- Trial name
- NCT05780918
- Testing
- Best Case/Worst Case-ICU Communication Tool
- Where
- 8 sites in United States
- Volunteers
- 7,320 people
- Sponsor
- University of Wisconsin, Madison
Pediatric Congenital Heart Surgery
Predictive Value of the FORE-SIGHT™ Monitor for Hemodynamic Deterioration
The postoperative period after congenital heart surgery in children can be a very critical episode, where it is of utmost importance to closely monitor the circulation in these patients.
- Trial name
- NCT01706497
- Testing
- Cerebral tissue oxygen saturation monitoring, blinded
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- KU Leuven
Anesthesia, Surgery--Complications
PACU for Postoperative Care After Major Thoracic and Abdominal Surgery
The aim of this study is to demonstrate the efficacy and safety of a specialised post-anaesthetic care unit (PACU) to a conventional intensive care unit (ICU) in adult patients after major thoracic and abdominal surgery.
- Trial name
- NCT05046925
- Testing
- postoperatively transferral to PACU, postoperatively transferral to ICU
- Where
- China
- Volunteers
- 18,000 people
- Sponsor
- First Affiliated Hospital of Zhejiang University