Clinical trials: Surgery, Thoracic
Surgery
The TransEnterix European Patient Registry
An open label observational registry trial in which participating centers enroll subjects who had or will have a laparoscopically assisted surgery using the Senhance Surgical System.
- Trial name
- TRUST (NCT03385109)
- Testing
- Surgery
- Where
- Germany
- Volunteers
- 4,080 people
- Sponsor
- Asensus Surgical
Abdominal Surgery, Thoracic Surgery
Parent/Nurse Controlled Analgesia in the Neonatal Intensive Care Unit
The aim of this study is to examine the safety and effectiveness of 2 morphine delivery systems for post-surgical neonates. The investigators hypothesize that this study will be feasible to conduct, and that neonates receiving…
- Trial name
- PNCA (NCT01823497)
- Testing
- Morphine
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Medical College of Wisconsin
Breast Surgery, Thoracic Paravertebral Block
Effect of Thoracic Paravertebral Block on Heart Rate Variability (HRV)
The Left thoracic paravertebral block have a different effect on heart's autonomic nervous system, as measured with Heart Rate Variability, compared to Right interscalene block
- Conditions
- Breast Surgery, Thoracic Paravertebral Block, HRV, Autonomic Nervous System
- Trial name
- NCT01755910
- Testing
- Left thoracic paravertebral block, Right thoracic paravertebral block
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Larissa University Hospital
Pulmonary Rehabilitation, Telerehabilitation
The Effect of a Mobile Application on Enhancing Pulmonary Rehabilitation After Lung Cancer Surgery
The goal of this clinical trial is to investigate the effect of a mobile application intervention on postoperative lung rehabilitation. The main purposes of this study are: 1.
- Conditions
- Pulmonary Rehabilitation, Telerehabilitation, Lung Cancer
- Trial name
- NCT06600503
- Testing
- RehabLung mobile application, Lung cancer postoperative standard care, Healthcare interactive Web Platform
- Volunteers
- 36 people
- Sponsor
- National Cheng Kung University
Coronary Artery Bypass
One-lung Ventilation During Internal Thoracic Artery Grafting in Cardiac Surgery
Coronary artery bypass grafting is a current cardiac surgery. Internal thoracic artery is usually taking to restore coronary revascularization, and its dissection can lead to accidental or voluntary pleural effusions.
- Trial name
- VUPPAM (NCT02823054)
- Testing
- EZ-Blocker
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Thoracic Surgery, Cardiopulmonary Bypass
Cerebral Autoregulation Monitoring During Cardiac Surgery
Neurological complications from cardiac surgery are an important source of operative mortality, prolonged hospitalization, health care expenditure, and impaired quality of life.
- Trial name
- NCT00981474
- Testing
- blood pressure maintenance based on cerebral blood flow autoregulation measurement, Control group
- Where
- United States
- Volunteers
- 460 people
- Sponsor
- Northwestern University
Bicuspid Aortic Valve, Aortic Valve Stenosis
Progression of Ascending Aorta Diameters in Bicuspid Aortic Valve After Transcatheter or Surgical Replacement.
The goal of this prospective, non-randomized, single-center, observational study is to assess whether there is a progressive dilation of ascending aorta after surgical or transcatheter aortic valve replacement (TAVR) in patients…
- Conditions
- Bicuspid Aortic Valve, Aortic Valve Stenosis, Aortic Aneurysm, Heart Diseases
- Trial name
- ARDITAV (NCT05708118)
- Testing
- Echocardiographic assessment., Computed-tomography assessment
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lung Cancer
Concomitant Tracheostomy and Lung Resection
This protocol has been designed to determine if tracheostomy performed immediately after lung operation (i.e. concomitant tracheotomy) could improve the postoperative outcome of high risk patients.
- Trial name
- NCT01053624
- Testing
- Tracheostomy
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hyperoxia
The Effect of Decreasing the Inspired Oxygen Concentration on Post-Operative Oxygenation After Primary Lobectomy
The purpose of this study is to test the hypothesis that decreasing the inspired oxygen concentration during thoracic surgery requiring one lung ventilation will improve post-operative oxygenation.
- Trial name
- NCT02509182
- Testing
- 60% oxygen, 100% oxygen
- Where
- United States
- Sponsor
- Yale University
Lung Cancer
ERAS Compliance and Nutritional Outcomes After Lung Cancer Surgery
This prospective observational study will evaluate the association between ERAS protocol compliance and postoperative nutritional outcomes in 120 patients undergoing lung cancer surgery.
- Trial name
- ERAS-NUTRI (NCT07785791)
- Testing
- Routine ERAS Perioperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bursa City Hospital
Diaphragm Dysfunction
Point of Care Ultrasound to Evaluate Diaphragmatic Function in Children Undergoing Thoracic Surgery
In children undergoing pulmonary resection, the diaphragm function is evaluated using ultrasound before and after surgery to evaluate the incidence of diaphragm dysfunction after pulmonary resection.
- Trial name
- NCT04400370
- Testing
- Diaphragm ultrasound
- Where
- South Korea
- Volunteers
- 75 people
- Sponsor
- Seoul National University Hospital
Aortic Aneurysm, Thoracic
Impact of Anesthesia on the Dimension of the Ascending Aorta
The aim of this study is to evaluate the accuracy and reliability of intra-operative TEE after the induction of anesthesia when assessing proximal thoracic aorta diameters in a cohort of aortic aneurysm patients.
- Trial name
- NCT03431870
- Testing
- Trans-esophageal echocardiography
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Non-small Cell Lung Cancer
Assisted-VATS Sleeve Lobectomy for Non-small Cell Lung Cancer
The purpose of this study is to examine the feasibility of assisted-VATS (video-assisted thoracoscopic surgery) sleeve lobectomy for non-small cell lung cancer for non-small cell lung cancer.
- Trial name
- VATS (NCT00997724)
- Testing
- a-VATS
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Postoperative Pain
Comparison of Erector Spinae Plane Block With Thoracic Paravertebral Block for Video Assisted Thoracoscopic Surgery
Erector Spinae Plane Block (ESPB) is a newly described and effective interfascial plane block for thoracic and abdominal surgery. It was first described by Forero et al. in 2016, effectiveness being reported in four cases.
- Trial name
- NCT03538496
- Testing
- Bupivacaine Hcl 0.25% Inj
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Chest Wall Tumor
Clinical Trial on the Efficacy and Safety of Biodegradable 3D-Printed Implants in Chest Wall Reconstruction Surgery
This project focuses on patients with chest wall tumors who are expected to have a maximum intraoperative anterolateral chest wall defect diameter of 5-10 cm and require chest wall reconstruction with rib implants.
- Trial name
- NCT06977022
- Testing
- Chest wall reconstruction
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Tang-Du Hospital
Malignant Mesothelioma
Pemetrexed Disodium and Cisplatin Followed By Surgery and Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma
RATIONALE: Drugs used in chemotherapy, such as pemetrexed disodium and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00227630
- Testing
- cisplatin, pemetrexed disodium, adjuvant therapy
- Where
- 8 sites in Belgium, Italy and 2 more
- Volunteers
- 59 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Anesthesia, Analgesia
Subcostal Approach to Anterior Quadratus Block Versus Thoracic Paravertebral Block for Laparoscopic Nephrectomy
In this study, it was aimed to evaluate the effects of subcostal anterior quadratus lumborum block (S-QLB3) and thoracic paravertebral block (TPVB) on postoperative acute pain scores and opioid consumption in the first 24 hours…
- Conditions
- Anesthesia, Analgesia, Acute Pain, Patient Controlled Analgesia
- Trial name
- NCT05191966
- Testing
- Subcostal Anterior Quadratus Lumborum Block, Thoracic Paravertebral Block
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ondokuz Mayıs University
Delirium, Thoracic Surgery
Cerebral Oxygen Desaturation and Post-Operative Delirium in Thoracic Surgical Patients
This study will assess the incidence and risk factors for post-operative delirium in patients undergoing thoracotomy. Specifically, the study will assess if there is any relationship between an intra-operative decrease in brain…
- Trial name
- NCT03165539
- Testing
- Cerebral oxygen saturation monitoring
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Manitoba
Lung Diseases
The Feasibility and Safety of Avoiding Chest Tube Placement After Video-assisted Thoracoscopic Surgery (VATS）of the Lung
This is a prospective randomized controlled trial.The main study content is the feasibility and safety of avoiding chest tube placement after Video-Assisted Thoracoscopic Surgery lung disease,participants were randomly divided…
- Trial name
- NCT04012554
- Testing
- avoid chest drainage tube placement after video-assisted thoracoscopic wedge resection of lung, Indewlling chest drainage tube after video-assisted thoracoscopic wedge resection of lung
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xueying Yang
Lung Cancer
Combination Chemotherapy Followed by Surgery in Treating Patients With Non-small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug with surgery may kill more tumor cells.
- Trial name
- NCT00003231
- Testing
- cisplatin, docetaxel, surgical procedure
- Where
- 9 sites in Switzerland
- Volunteers
- 40 people
- Sponsor
- Swiss Cancer Institute