Clinical trials: Surgery Indication
Leiomyoma, Leiomyosarcoma
Development of a Predictive Model for Early Differential Diagnosis of Uterine Leiomyomas and Leiomyosarcomas
The development of an accurate and non-invasive diagnostic method is a priority in areas such as gynecology and oncology, specifically to improve the health of those patients with surgical indication for diagnosis of myometrial…
- Trial name
- MYOSARC (NCT04214457)
- Testing
- Biopsy and peripheral blood collection
- Where
- 4 sites in Spain
- Volunteers
- 1,000 people
- Sponsor
- Igenomix
Rheumatoid Arthritis, Osteoarthritis
A Multi-centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery
The purpose of this study is to monitor the performance and determine the metal ion release of the DePuy ASR™ System in the treatment of patients with hip joint disease requiring hip resurfacing surgery.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders
- Trial name
- NCT00208377
- Testing
- DePuy ASR Hip System
- Where
- 3 sites in Australia, Germany and 1 more
- Volunteers
- 228 people
- Sponsor
- DePuy International
Peroneal and Achilles Tendon Tears
Peroneal and Achilles Tendon Repair Indications With CLARIX® CORD 1K
Peroneal and Achilles tendon tears are common diseases that present challenges to surgeons due to tendon adhesion complications.
- Trial name
- PATRICC (NCT02719288)
- Testing
- CLARIX® CORD 1K graft
- Where
- 4 sites in United States
- Volunteers
- 64 people
- Sponsor
- Amniox Medical, Inc.
GYN Disorders
ROBYN Study - Robotic Assisted Surgery in Gynecological Indications Compared to Conventional Laparoscopy
Robotic Assisted Surgery (da Vinci System) in gynecological indications compared to conventional laparoscopy
- Trial name
- ROBYN (NCT05496244)
- Testing
- Laparoscopy, Robotic-assisted surgery
- Sponsor
- Intuitive Surgical
Renal Cell Carcinoma
Pucotenlimab Combined With Lenvatinib as a Neodjuvant Therapy for Non Clear Cell Renal Cell Carcinoma
Through the neoadjuvant treatment with a combination of Pucotenlimab and Lenvatinib, it eventually enables the successful and safe implementation of partial nephrectomy in patients with localized renal cancer, who have…
- Trial name
- NCT06129955
- Testing
- Pucotenlimab Combined With Lenvatinib
- Where
- China
- Volunteers
- 47 people
- Sponsor
- Sun Yat-sen University
Pancreatic Surgery, Children
Children in Pancreatic Surgery: Indications, Procedures and Outcomes
Pediatric patients differ in a variety of properties from adult populations, but comprehensive multicenter or population-based data is missing for pancreatic surgery.
- Trial name
- ChiPS (NCT07293104)
- Testing
- Pancreatoduodenectomy, Total pancreatectomy, Distal pancreatectomy
- Volunteers
- 761 people
- Sponsor
- Medizinische Hochschule Brandenburg Theodor Fontane
Patellofemoral Osteoarthritis, Arthroplasty Complications
Failure Analysis of Patellofemoral Arthroplasty
The purpose of the retrospective cohort study is 1) to determine preoperative risk factors for revision af patellofemoral arthroplasty, and 2) to provide a detailed description of indications for revision after patellofemoral…
- Conditions
- Patellofemoral Osteoarthritis, Arthroplasty Complications, Knee Osteoarthritis
- Trial name
- NCT04772625
- Testing
- Patellofemoral arthroplasty
- Where
- Denmark
- Volunteers
- 550 people
- Sponsor
- Anders Odgaard
Colorectal Surgery
A Single Dose of a Marketed Drug Being Studied for a New Indication to Treat Surgical Site Infection Following Colorectal Surgery as Compared to a Marketed Drug Approved for This Indication (0826-039)
The objective of this study is to evaluate the safety and efficacy of a one time dose of an intravenous marketed drug being evaluated for a new indication as compared to a marketed drug already approved for the prevention of…
- Trial name
- NCT00090272
- Testing
- MK0826, ertapenem sodium, Comparator: cefotetan
- Volunteers
- 952 people
- Sponsor
- Merck Sharp & Dohme LLC
Periodontitis, Coronariopathy
Non-surgical Periodontal Treatment on Hemogram, Lipid and Glycemic Profiles in Patients With Coronariopathies
Objective: The aim of this study was to examine the effects of non-surgical periodontal treatment on the hemogram, glycemic and lipid profiles in cardiopathic patients with an indication for surgical revascularization.
- Trial name
- NCT02150005
- Testing
- Periodontal treatment
- Volunteers
- 22 people
- Sponsor
- Universidade Veiga de Almeida
Liver Cancer, Liver Metastases
Impact of Minimally Invasive and Open Liver Surgery in Different BMI-classes
Despite the worldwide increase of both obesity and use of minimally invasive liver surgery(MILS), evidence regarding the safety and eventual benefits of MILS in obese patients is scarce.
- Conditions
- Liver Cancer, Liver Metastases, Obesity
- Trial name
- MILSOBES (NCT05475054)
- Testing
- Minimally invasive liver resection
- Where
- Italy
- Volunteers
- 9,963 people
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Cataracts, Cataract Surgery
Aberrometry and Straylight Measurements as an Indication for Cataract Surgery
Cataracts are a clouding of the lens of the eye. Cataract surgery replaces the cloudy lens with a clear artificial lens. It is one of the leading causes of low vision worldwide.
- Trial name
- ASICS (NCT06257914)
- Testing
- Catquest-9SF
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Amphia Hospital
Pancreatic Cancer, Liver Metastases
The Significance and Indications of Surgery for Synchronous Liver Metastatic Pancreatic Cancer
To explore the clinical characteristics of pancreatic cancer patients with liver metastases who can benefit from surgery, and to develop evaluation criteria for surgical indications, so as to provide basis for comprehensive…
- Conditions
- Pancreatic Cancer, Liver Metastases, Surgery, Adjuvant Therapy
- Trial name
- PCLM:CSSG (NCT06873178)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- China-Japan Friendship Hospital
Acute Cholecystitis
Early Versus Delayed Laparoscopic Cholecystectomy for Acute Cholecystitis
The goal of this clinical trial is to learn if performing gallbladder surgery early is as safe and effective as delaying it for people with acute cholecystitis (a sudden gallbladder infection).
- Trial name
- EDLC-AC (NCT07101315)
- Testing
- Laparoscopic Cholecystectomy
- Where
- 2 sites in Yemen
- Volunteers
- 81 people
- Sponsor
- Sana'a University
Gastric Bypass Surgery, Revisional Bariatric Surgery
Reversal of Roux-en-Y Gastric Bypass: A Swedish National Cohort Study
Objective: To investigates incidence, indications, symptom relief, complications, and weight outcomes after Roux-en-Y gastric bypass (RYGB) reversal.
- Conditions
- Gastric Bypass Surgery, Revisional Bariatric Surgery, Complications After Bariatric Surgery
- Trial name
- NCT07347093
- Where
- Sweden
- Volunteers
- 199 people
- Sponsor
- Vrinnevi Hospital
Glioblastoma
Dose Finding for Intraoperative Photodynamic Therapy of Glioblastoma
The phase II study evaluate a light dose escalation in a classical intraoperative PDT regimen mediated by 5-ALA-PpIX, in glioblastoma patients with access to full surgical removal of the contrast enhancement.
- Trial name
- DOSINDYGO (NCT04391062)
- Testing
- Gliolan, Intraoperative PDT
- Where
- 2 sites in Belgium, France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Lille
Aortic Aneurysm, Abdominal, Ventricular Arrythmia
Cardiac Complication After Vascular Surgery
The vascular surgery is a highest risk procedure when considering postoperative complications associated with the cardiovascular system. The leading clinical presentation is acute hemodynamic decompensation.
- Conditions
- Aortic Aneurysm, Abdominal, Ventricular Arrythmia, Peripheral Arterial Disease, Cardiac Complication
- Trial name
- CCVS (NCT03188341)
- Testing
- vascular surgery procedure
- Volunteers
- 100 people
- Sponsor
- Pomeranian Medical University Szczecin
Periampullary Carcinoma, Pancreatic Cancer
Reoperation After Pancreaticoduodenectomy
The aim of this study is to outline the incidence of early and late reoperation after PD, examine the risk factors for early surgical intervention and its impact on the surgical outcome, hospital stay, diseases recurrence and…
- Trial name
- NCT04387903
- Testing
- Surgical re-interventionafter pancreaticoduodenectomy
- Volunteers
- 1,000 people
- Sponsor
- Mansoura University
Vascular Disease
ArterX Safety and Efficacy Study for Cardiac Indications
The study is designed to confirm the acute safety and performance of the ArterX® Surgical Sealant as a hemostatic agent. The study will collect data in support of publications and future product labeling revisions, to provide…
- Trial name
- NCT01957904
- Testing
- ArterX Surgical Sealant
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- Tenaxis Medical, Inc.
Esophageal Cancer, Surgery Indication
Evaluation of the Administration of Artificial Nutrition by Feeding Jejunostomy During Neoadjuvant Treatment on Postoperative Morbidity in the Context of Esophageal or Stomach Cancer
Malnutrition is common at the time of diagnosis of esogastric cancers. However, there are no recommendations regarding preoperative nutritional support (type and duration) or on the impact of refeeding on postoperative morbidity…
- Conditions
- Esophageal Cancer, Surgery Indication, Malnourished, Neoadjuvant Treatment
- Trial name
- FREJENO (NCT07584577)
- Testing
- Enteral or parenteral nutrition
- Where
- France
- Volunteers
- 670 people
- Sponsor
- University Hospital, Bordeaux
Paroxysmal Atrial Fibrillation, Indications for CABG
Botulinum Toxin Injection in Epicardial Fat Pads To Treat Atrial Fibrillation After Cardiac Surgery
The aim of this prospective randomized double-blind study was to compare the efficacy and safety of Botulinum toxin injection in epicardial fat pads for preventing recurrences (in early postoperative period) of atrial…
- Trial name
- NCT01842529
- Testing
- botulinum toxin injection, 0.9% normal saline injection, Implantable loop recorder
- Where
- 3 sites in United States, Russia
- Volunteers
- 60 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation