Clinical trials: Surgery With General Anesthesia
164 Boys for Hypospadias Surgery Under General Anesthesia With Caudal Block
Caudal Dexmedetomidine Analgesia in Pediatrics .
Dexmedetomidine (DEXM) is a highly selective α2-adrenoceptor agonist that has been used increasingly in pediatric anesthesia. This prospective double blinded randomized comparative study is designed to evaluate the analgesic…
- Trial name
- NCT03791879
- Testing
- Caudal dexamedatomidine analgesia
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Mansoura University
Postoperative Residual Curarization, Residual Neuromuscular Block
Comparison Between Cisatracurium and Rocuronium in Terms of Recovery of the Muscular Strength in the Postoperative Phase After Surgery and General Anaesthesia
The purpose of this study is to determine the incidence of post-operative residual curarization in our patients and to determine if Cisatracurium and Rocuronium behave differently from each other in terms of residual curarization.
- Trial name
- NCT01651572
- Testing
- Cisatracurium, Rocuronium
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliera di Padova
Anesthesia, Intravenous, Hemodynamic Stability
Hemodynamic Effects of Remimazolam vs Propofol During Robot-assisted Gynecologic Surgery
This single-center study at CHA Ilsan Medical Center compares intraoperative hemodynamics between remimazolam- and propofol-based total intravenous anesthesia (TIVA) in patients undergoing robot-assisted gynecologic surgery…
- Conditions
- Anesthesia, Intravenous, Hemodynamic Stability, Gynecologic Surgery
- Trial name
- By_HD (NCT07251101)
- Testing
- Remimazolam, Propofol
- Where
- 2 sites in South Korea
- Volunteers
- 58 people
- Sponsor
- Ilsan Cha hospital
Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia, Deviated Nasal Septum
Anterior Ethmoidal Nerve Block in Prevention of Postoperative Agitation
Postoperative agitation is an important complication of general anesthesia, moreover, it has been found with high incidence in ear, nose, throat (ENT) surgeries.
- Conditions
- Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia, Deviated Nasal Septum, Chronic Rhinosinusitis (Diagnosis), Nasal Polyps
- Trial name
- NCT03427502
- Testing
- Bupivacaine-epinephrine, normal saline
- Where
- Nepal
- Volunteers
- 100 people
- Sponsor
- Lumbini Medical College
Surgical Procedure, Unspecified
Thoracic Epidural Versus General Anaesthesia in Cholecystectomy
CONTEXT AND AIMS: The aim of the study is to compare patients satisfaction of thoracic epidural and general anesthesia procedures in patients undergoing elective laparoscopic cholecystectomy.
- Trial name
- EVGAC (NCT03107832)
- Testing
- thoracic epidural anesthesia procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Abant Izzet Baysal University
Anesthesia, General, Neuromuscular Blockade
Comparison of 2.0 mg/kg Sugammadex and Neostigmine at Reappearance of T2 in Chinese and European Subjects (Study 19.4.324)(P05768AM1)(COMPLETED)
The present trial was set up to evaluate the efficacy and safety of 2.0 mg.kg-1 sugammadex compared to neostigmine administered at reappearance of T2 in Chinese and Caucasian subjects for registration purposes in China.
- Trial name
- NCT00825812
- Testing
- Sugammadex, neostigmine
- Volunteers
- 308 people
- Sponsor
- Merck Sharp & Dohme LLC
A Study on the Effect of Animation-based Nurse-Patient Interaction Model on Postoperative Pain in Children With Congenital Heart Disease
Application of Nurse-Patient Interaction Model Based on Animated Cartoons in Postoperative Analgesia for Preschool Children With Congenital Heart Disease.
I. Research Objective To verify the efficacy of an animated nurse-patient interaction model in alleviating postoperative pain in children with congenital heart disease, optimize non-pharmacological analgesic nursing processes for…
- Trial name
- CCU (NCT07319260)
- Testing
- Routine care
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Beijing Children's Hospital
Intertrochanteric Fractures
Blocks for Intertrochanteric Fracture Repair Surgery
This single-center open label study compares the outcomes of surgical repair of intratrochanteric fracture under general anesthetic or peripheral nerve blocks.
- Trial name
- NCT04470115
- Testing
- General anesthesia, Regional anesthesia- femoral and lateral femoral cutaneous nerve blocks
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Military Institute od Medicine National Research Institute
Shouldersurgery
Assessing Cerebral Blood Flow Autoregulation During Surgery in the Head-up Position
Neurological injury after elective shoulder surgery in the beach chair position is thought to result from cerebral hypoperfusion and should therefore be preventable by appropriate hemodynamic monitoring and management.
- Trial name
- NCT01225185
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Johns Hopkins University
Lung Resection Surgery, Anesthesia General
Effect of Oxygen Administration in the Non-dependent Lung on Postoperative Complications After Lung Surgery
The purpose of this study is to analyze the effectiveness of apneic oxygenation and CPAP applied to the non-dependent lung during pulmonary resection surgery in reducing inflammatory response, ischemia-reperfusion injury, and…
- Trial name
- NCT07461779
- Testing
- Medicinal gas - oxygen (Nippon Gases 200 bar), CPAP, Oxygen therapy according to standard clinical practice
- Where
- Spain
- Volunteers
- 177 people
- Sponsor
- Francisco Andres de la Gala
Nausea, Emesis
Post- Surgery Recovery: Nerve Blocks w/ Sedation vs. Nerve Block w/ Either Sedation/Gen. Anesthesia
Nausea after surgery may negatively influence patient satisfaction, may delay discharge, and cause unexpected hospital admissions.
- Trial name
- NCT02602080
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Hospital for Special Surgery, New York
Breast Cancer Female
Does Type of Anesthesia Influence Inflammation Change After Breast Surgery?
The Neutrophil to Lymphocyte Ratio (NLR) is a frequently used biomarker of the systemic inflammatory response and is considered one of the most sensitive markers of inflammation.
- Trial name
- NCT04172220
- Testing
- Midazolam, PECS, Opioid-free general anesthesia
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- Centro di Riferimento Oncologico - Aviano
General Anesthesia, Laryngeal Mask
Application of Visual Laryngeal Mask Airway Combined With Endotracheal Intubation in General Anesthesia
To study the advantages of visual laryngeal mask combined with endotracheal intubation in general anesthesia surgery, we compared intubation time, intubation times and intubation success rate of endotracheal intubation through…
- Conditions
- General Anesthesia, Laryngeal Mask, Endotracheal Intubation, Surgery
- Trial name
- NCT04719767
- Testing
- visual laryngeal mask
- Volunteers
- 50 people
- Sponsor
- Peking Union Medical College Hospital
Post Operative Pain
Efficacy of Parecoxib Combined With Paracetamol in Mastectomy
Patients undergoing breast cancer surgery experience persistent pain after surgery and subsequent development of chronic pain. Parecoxib or paracetamol has been reported to reduce postoperative pain in mastectomy.
- Trial name
- NCT05757388
- Testing
- Parecoxib + paracetamol, Normal saline
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Khon Kaen University
Hernia Repair, Orchiopexy
Postoperative Pain Relief in Children: Comparing Caudal Bupivacaine Alone Versus Bupivacaine With Dexmedetomidine for Infra-Umbilical Surgeries Under General Anesthesia
This study is being done to find out which medicine combination provides better pain relief after surgery in children. Children who are having surgery below the belly button (called infra-umbilical surgery) will receive general…
- Conditions
- Hernia Repair, Orchiopexy, Hypospadias
- Trial name
- NCT07121764
- Testing
- Bupivacaine %0.25 (isobaric), Dexmedetomidine & Bupivacaine.
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Allama Iqbal Teaching Hospital
Abdominal Pain
Lateral Quadratus Lumborum Block Versus Transversus Abdominis Plane Block in Laparoscopic Surgery
The transversus abdominis plane (TAP) block is an already established technique and is considered now as an efficient part of the multimodal pain management approach for abdominal surgical procedures.
- Trial name
- NCT04553991
- Testing
- Ultrasound guided QL block, Ultrasound guided TAP block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Fayoum University Hospital
Post-Op Complication, Pain, Postoperative
TAP Block On Abdominal Surgery Patients With General Anesthesia
INTRODUCTION: The aim of this study was to investigate the effects of tranversus abdominis plane (TAP) block placed postoperatively using ultrasound guidance for patients with caesarean section, myomectomy and hysterectomy under…
- Trial name
- TAPBLOCK (NCT04364477)
- Testing
- transversus abdominis plane (TAP) block
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University Hospital
Tissue Perfusion, Lower Extremity Surgery
Comparison of the Effects of General Anesthesia and Spinal Anesthesia on Tissue Perfusion in Patients Undergoing Lower Extremity Surgery
This prospective, single-center observational study compares the effects of general anesthesia and spinal anesthesia on tissue perfusion in patients undergoing lower extremity surgery with tourniquet use.
- Conditions
- Tissue Perfusion, Lower Extremity Surgery, Tourniquet-Induced Ischemia-Reperfusion Injury, General Anesthesia
- Trial name
- Perf-LEX (NCT07474480)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Combination of General Anesthesia to Spinal and Epidural Techniques
Combination of Spinal-Epidural With General Anesthesia in Patients Undergoing Mega-Liposuction Surgery
The combination of general anesthesia to spinal and epidural techniques (CSEGA) proved to have a synergistic effect, thus, the use of sub-anesthetic doses can provide satisfactory anesthetic and analgesic results.
- Trial name
- NCT05301127
- Testing
- spinal-epidural device
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tympanum; Perforation
General Anesthesia With or Without Local Ear Block in Middle Ear Surgeries
Background: Proper selection of anesthetic technique is important in middle ear microsurgery. Controlled hypotension in ear surgery decreases blood loss with improved quality of the surgical field, however, it is associated with…
- Trial name
- NCT03569046
- Testing
- local anaesthetic injection, Normal Saline Flush, 0.9% Injectable Solution, general anesthetic
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Abd-Elazeem Abd-Elhameed Elbakry