Clinical trials: Surgery With General Anesthesia
Cholecystectomy, Laparoscopic, Anesthesia, General
Comparison of Pupillometry-guided Anesthesia With Surgical Pleth Index Guided Anesthesia
In this study, the investigators measure a pupil size every 5 minutes during the operation in patients undergoing laparoscopic cholecystectomy under general anesthesia.
- Conditions
- Cholecystectomy, Laparoscopic, Anesthesia, General, Reflex, Pupillary
- Trial name
- PUPIL (NCT03586791)
- Testing
- Pupillometry guided anesthesia, SPI guided anesthesia, Standard management
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Daegu Catholic University Medical Center
Chronic Subdural Hematoma, Anesthesia
Nerve Block Anesthesia Combined With Sedative Anesthesia Versus General Anesthesia in Surgery for CSDH
A prospective, multicenter, randomized controlled trial is designed to evaluate the safety of nerve block anesthesia combined with sedative anesthesia versus general anesthesia during burr hole craniostomy with drainage for…
- Trial name
- NCT05888389
- Testing
- Cranial Nerve Block Anesthesia Combined With Sedative Anesthesia, General Anesthesia
- Where
- China
- Volunteers
- 190 people
- Sponsor
- Beijing Tiantan Hospital
Gallbladder Disease
Effect IV Ibuprofen and Inflammatory Responses
This study is being done because the investigators wish to study ways to improve recovery after surgery. Injury, including surgical injury, causes inflammation.
- Trial name
- NCT01938040
- Testing
- ibuprofen
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Abdominal Pain
Lateral Quadratus Lumborum Block Versus Transversus Abdominis Plane Block in Laparoscopic Surgery
The transversus abdominis plane (TAP) block is an already established technique and is considered now as an efficient part of the multimodal pain management approach for abdominal surgical procedures.
- Trial name
- NCT04553991
- Testing
- Ultrasound guided QL block, Ultrasound guided TAP block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Fayoum University Hospital
Combination of General Anesthesia to Spinal and Epidural Techniques
Combination of Spinal-Epidural With General Anesthesia in Patients Undergoing Mega-Liposuction Surgery
The combination of general anesthesia to spinal and epidural techniques (CSEGA) proved to have a synergistic effect, thus, the use of sub-anesthetic doses can provide satisfactory anesthetic and analgesic results.
- Trial name
- NCT05301127
- Testing
- spinal-epidural device
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hemodynamic (MAP) Stability
Unilateral Spinal vs General Anaesthesia in Low EF Patients: A Hemodynamic Comparison
A difference exists in intraoperative hemodynamic stability and vasopressor requirement between the two techniques
- Trial name
- NCT07752303
- Testing
- Unilateral spinal anesthesia, General anesthesia
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Sargodha Medical College
Frailty, Neuromuscular Blockade
Incidence of Residual Neuromuscular Blockade in Fraility in OncoGynae Surgery
Frailty among patients undergoing surgery is strongly associated with an elevated risk of adverse perioperative outcomes, heightened incidence of postoperative complications, increased mortality rates, and prolonged hospital…
- Conditions
- Frailty, Neuromuscular Blockade, General Anesthetic Drug Adverse Reaction, Gynecologic Cancer
- Trial name
- FIGO (NCT06216002)
- Testing
- Train of four nerve stimulator
- Where
- Thailand
- Volunteers
- 356 people
- Sponsor
- Mahidol University
Orthopedic/Podiatry Procedures
Effects of Dexmedetomidine on Tourniquet Pain Associated With Lower Extremity Surgeries Under General Anesthesia
This study is being done to determine if the drug known as dexmedetomidine improves the way we care for patients when their surgery involves the use of a tourniquet on the leg.
- Trial name
- NCT00932386
- Testing
- Dexmedetomidine Hcl infusion, normal saline
- Where
- United States
- Sponsor
- Rutgers, The State University of New Jersey
Colorectal Neoplasms
DEXDES Trial: Dexmedetomidine-Desflurane Combination in Laparoscopic Colectomy
This randomized double-blind controlled clinical trial aims to evaluate the efficacy and safety of combining Dexmedetomidine with Desflurane in patients undergoing elective laparoscopic colectomy.
- Trial name
- NCT07239479
- Testing
- Dexmedetomidine + Desflurane, Desflurane + Normal Saline
- Where
- Vietnam
- Volunteers
- 40 people
- Sponsor
- Tam Anh Research Institute
Patients With Breast Cancer and Breast Surgery Requiring
Assessment of Cognitive Function After Surgery in Two Types of Anesthesia in Patients Operated for Breast Cancer
The emergence of cognitive disorders after surgery under general anesthesia (GA) is the second leading cause of patient complaints (after dental debris caused by intubation techniques).
- Trial name
- HYPNOSEIN (NCT01880541)
- Testing
- hypnosedation, general anesthésia
- Where
- 3 sites in France
- Volunteers
- 30 people
- Sponsor
- Institut Bergonié
Recovery
Comparison of Recovery From General Anesthesia in Remimazolam With Flumazenil vs. Propofol
This prospective randomized trial aims to compare recovery time from discontinuation of remimazolam followed by flumazenil administration vs.
- Trial name
- NCT05435911
- Testing
- REMIMAZOLAM BESYLATE 2.5 Mg in 1 mL INTRAVENOUS INJECTION, POWDER, LYOPHILIZED, for SOLUTION [BYFAVO], Flumazenil, Propofol
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Seoul National University Hospital
Pain Management, Regional Anesthesia
Revision of Deep Brain Stimulator in Patients With Parkinson's Disease
Parkinson's disease is a chronic and progressive neurodegenerative disease that affects the central nervous system, particularly impairing movement control.
- Conditions
- Pain Management, Regional Anesthesia, Deep Brain Stimulation, Parkinsons Disease
- Trial name
- NCT07176494
- Testing
- Patients who underwent surgery under general anesthesia, Patients who underwent surgery under regional anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara Etlik City Hospital
Patients Undergoing General Anesthesia
Deep Neuromuscular Block With Pipecuronium in Patients Undergoing Robotic Thoracic Surgery
Robotic-assisted surgery is rapidly expanding across surgical specialties, including thoracic surgery. Compared with conventional techniques, robotic surgery provides the surgeon with a three-dimensional view and highly precise…
- Trial name
- Deep block (NCT07868094)
- Testing
- Electromiograph
- Where
- Hungary
- Volunteers
- 19 people
- Sponsor
- University of Debrecen
Anesthesia, Cognitive Dysfunction
Evaluation of Cognitive Functions by Cerebral Pulse Oximetry
General and Spinal Anesthesia can be used in geriatric patients in orthopedic surgery. Post-op cognitive dysfunction can be seen in orthopedic surgeries in this group of patients.
- Trial name
- NCT03827083
- Testing
- cerebral pulse oximetry
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Hypotension During Surgery
Effect of Titrated Administration of Ciprofol on Perioperative Hypotension in Elderly Patients Undergoing Laparoscopic Abdominal Surgery: A Randomized Controlled Trial
Elderly patients are frequently burdened with age-associated comorbidities and frailty, accompanied by physiological changes such as vascular stiffening, cardiac dysfunction, and impaired autonomic regulation.
- Trial name
- TAPH (NCT07328958)
- Testing
- titrated anesthesia
- Where
- 2 sites in China
- Volunteers
- 500 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
General Surgery With Endotracheal Intubation
The Effect Site Concentration of Remifentanil for Preventing QTc Interval Prolongation During Intubation Under Propofol-remifentanil Anesthesia in Elderly Patients
To find out the effect site concentration of remifentanil for preventing QTc interval prolongation during intubation under propofol-remifentanil anesthesia in elderly patients
- Trial name
- NCT01720498
- Testing
- remifentanil
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Severance Hospital
High-flow Nasal Cannula, Oxygenation
High-Flow Nasal Oxygen for Preoxygenation in Emergency Surgery Patients With Full Stomachs
Patients with full stomachs face a high risk of regurgitation and aspiration under general anesthesia. To minimize the time between the loss of airway protective reflexes and successful tracheal intubation, rapid sequence…
- Conditions
- High-flow Nasal Cannula, Oxygenation, General Anesthesia, Induction Anesthesia
- Trial name
- HFNC (NCT06879600)
- Testing
- High-flow nasal cannula therapy application, Traditional facemask
- Where
- Vietnam
- Volunteers
- 200 people
- Sponsor
- Nguyen Dang Thu
Strabismus
Peribulbar Block for Prevention of Oculocardiac Reflex
Strabismus is a common ophthalmic problem in Egypt that usually requires surgical correction. This surgery primarily aims to improve alignment of visual axis but may be required only for cosmetic reasons.
- Trial name
- NCT04549844
- Testing
- Bupivacaine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Fayoum University Hospital
Abdominal Surgery
Effects of ACBT and Blow Bottle Technique in Patients With Abdominal Surgeries Under General Anesthesia
A postoperative pulmonary complication (PPC) is the most common serious complication after Abdominal surgery under GA which lead to longer hospital stays and have deleterious outcomes on lung volumes, mucociliary clearance…
- Trial name
- NCT06454305
- Testing
- Active cycle of breathing technique, Blow Bottle Technique
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
General Anesthesia, Aged
Remimazolam Versus Midazolam for General Anesthesia Induction in Elderly Patients Undergoing Non-Cardiac Surgery
This prospective observational cohort study evaluates the effectiveness and safety of two benzodiazepine sedatives-remimazolam and midazolam-used for general anesthesia induction in elderly patients (≥65 years) undergoing…
- Conditions
- General Anesthesia, Aged, Intraoperative Hypotension, Anxiety
- Trial name
- NCT07746505
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine