Clinical trials: Surgery for Colorectal Cancer.
Colon Neoplasms
A Novel Technique of HALS With CME and CVL for RCC
The purpose of this study is to determine the short and long outcomes of the novel technique of hand-assisted laparoscopic right hemicolectomy with complete mesocolic excision and central vascular ligation for right colon cancer.
- Trial name
- NCT02625272
- Testing
- Group A
- Where
- China
- Volunteers
- 60 people
- Sponsor
- West China Hospital
Colorectal Neoplasm, Effects of Radiation Therapy
Randomized Trial of Primary Surgery Followed Selective Radiochemotherapy for Rectal Cancer With MRI Negative CRM
The purpose of this study is to determine whether primary radiotherapy can be omitted for the locally advanced rectal cancer with Magnetic Resonance Imaging (MRI) negative circumferential margin.
- Conditions
- Colorectal Neoplasm, Effects of Radiation Therapy, Effects of Chemotherapy, Surgery
- Trial name
- PSSR (NCT02121405)
- Testing
- Rectectomy, Radiotherapy, Capecitabine
- Where
- 7 sites in China
- Volunteers
- 350 people
- Sponsor
- Zhejiang University
Breast Carcinoma, Head and Neck Cancer
Fluorescence for Sentinel Lymph Node Identification in Cancer Surgery
This is a single-center prospective clinical trial to evaluate non-inferiority of indocyanine green guided sentinel lymph node biopsy compared with the gold standard Technecium99 guided sentinel lymph node biopsy in patients with…
- Conditions
- Breast Carcinoma, Head and Neck Cancer, Melanoma (Skin), Squamous Cell Carcinoma, Skin
- Trial name
- GASVERT (NCT02997553)
- Testing
- Indocyanine green, Technetium99, Optonuclear probe
- Where
- France
- Volunteers
- 744 people
- Sponsor
- Institut de Cancérologie de Lorraine
Colorectal Cancer Metastatic, Peritoneal Metastases
Development of an IDEAL Framework to Standardise Cytoreductive Surgery for Colorectal Peritoneal Metastases
Cytoreduction surgery (CRS) followed by hyperthermic intra-operative peritoneal chemotherapy (HIPEC) is a relatively new treatment for selected patients with peritoneal metastases of colorectal origin (PMCR).
- Trial name
- IDEAL-PM (NCT03733184)
- Testing
- Cytoreduction and Heated Intraperitoneal Surgery
- Volunteers
- 200 people
- Sponsor
- University of Manchester
Postoperative Ileus, Colorectal Cancer
Role of Tibial Nerve Stimulation for Enhanced Postoperative Recovery After Colorectal Surgery
Aim of the study is to evaluate the role of postoperative tibial nerve stimulation in the enhancement of the recovery of bowel function and in shortening the hospital stay.
- Trial name
- TiRex (NCT02433938)
- Testing
- Tibial nerve stimulation
- Volunteers
- 160 people
- Sponsor
- University of Florence
Colorectal Cancer
Study to Evaluate Oxygen Monitoring at Different Stages of Neuromuscular Blockade in Colorectal Surgery
Anesthesia favouring deep/intense neuromuscular blockade during laparoscopy may restore hemodynamics. However, no studies has been performed comparing oxygenation parameters during laparoscopy in colorectal surgery in either…
- Trial name
- OXYMUBLOC (NCT02327494)
- Testing
- neuromuscular blockade
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Hospital Universitari de Bellvitge
Colorectal Cancer
Combination Chemotherapy and Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Locally Advanced Rectal Cancer
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00613080
- Testing
- capecitabine, oxaliplatin, resection
- Where
- 120 sites in United States, Canada
- Volunteers
- 79 people
- Sponsor
- Radiation Therapy Oncology Group
Rectal Neoplasms
Transanal Total Mesorectal Excision Versus Laparoscopic TME for Rectal Cancer
To investigates the feasibility, practicability, safety and subjective as well as functional outcome of transanal minimal invasive surgery toal mesentery excision for rectal cancer.
- Trial name
- NCT02252250
- Testing
- conventional laparoscopic total mesentery excision, transanal hybrid-laparoscopic total mesentery excision
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Third Military Medical University
Anxiety, Surgical Preparation, and Recovery Process in Colorectal Cancer Surgery
The Effect of Preoperative Training With Virtual Reality on Anxiety, Readiness for Surgery and Recovery Process of Patients in Colorectal Cancer Surgery
The aim of the study is to determine the effect of The Effect of Preoperative Training with Virtual Reality on Anxiety, Readiness for Surgery and Recovery Process of Patients in Colorectal Cancer Surgery.
- Trial name
- NCT07294690
- Testing
- Patients undergoing colorectal surgery will be trained using virtual reality glasses.
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Istanbul University - Cerrahpasa
Colorectal Cancer, Esophageal Cancer
Clinical Trial Protocol for Evaluating the Efficacy and Safety of Thoracoabdominal Endoscopic Surgery System in Remote Laparoscopic Surgery for Urology, General Surgery, Gynecology and Thoracic Surgery
Evaluation of the Efficacy and Safety of the Thoracoabdominal Endoscopic Surgery System Produced by Shenzhen Cornerstone Robotics Technology Co., Ltd.
- Conditions
- Colorectal Cancer, Esophageal Cancer, Hepatectomy, Radical Hysterectomy
- Trial name
- NCT07382635
- Testing
- Robot-assisted surgery
- Volunteers
- 98 people
- Sponsor
- Cornerstone Robotics
Colon Cancer, Rectal Cancer
Fit for Surgery. Multimodal Prehabilitation in Colorectal Cancer Patients
Randomized clinical trial of multimodal prehabilitation in vulnerable patients with colon or rectal cancer prior to surgery.
- Conditions
- Colon Cancer, Rectal Cancer, Frailty
- Trial name
- NCT04167436
- Testing
- Prehabilitation
- Where
- 2 sites in Denmark
- Volunteers
- 48 people
- Sponsor
- Zealand University Hospital
Colorectal Cancer
A Study of Xeloda (Capecitabine) as Adjuvant Monotherapy in Patients With Colon Cancer.
This single arm study will evaluate the safety profile of Xeloda as monotherapy for adjuvant treatment of colon cancer. All patients will receive Xeloda 1250mg/m2 p.o.
- Trial name
- NCT00502671
- Testing
- capecitabine [Xeloda]
- Where
- 46 sites in Russia
- Volunteers
- 228 people
- Sponsor
- Hoffmann-La Roche
Colorectal Cancer
Clinical Trial to Evaluate Safety and Efficacy of Hyperthermic Intra-peritoneal Chemotherapy (HIPEC) With Mitomycin C Used During Surgery for Treatment of Locally Advanced Colorectal Carcinoma
The purpose of this study is to determine whether Hyperthermic Intra-peritoneal Chemotherapy (HIPEC) with Mitomycin C used during surgery for treatment of locally advanced colorectal carcinoma is effective in the treatment of…
- Trial name
- HIPECT4 (NCT02614534)
- Testing
- MITOMYCIN-C 30 mg, Proactive cytoreductive surgery
- Where
- 19 sites in Spain
- Volunteers
- 200 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Metastatic Colon Cancer
A Phase Ⅱ Study of XELOX Chemotherapy With or Without Surgery of Primary Lesion for Colon Cancer Patients
The primary endpoint is to evaluate the TFS (time to failure of strategy).
- Trial name
- NCT02291744
- Testing
- resection of primary lesion, XELOX
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Fudan University
Angiogenesis, Colon Cancer
Postoperative VEGF and Recurrence After Colon Cancer Surgery
The purpose of this trial is to study the relationship between the angiogenic response to surgical aggression, determined through the serum levels of vascular endothelial growth factor (VEGF) on postoperative day four, and the…
- Conditions
- Angiogenesis, Colon Cancer, Surgery, Recurrence
- Trial name
- NCT04851054
- Testing
- Surgery for colon cancer with intention to cure
- Volunteers
- 280 people
- Sponsor
- Hospital del Mar
Laparoscopic Surgery, Colorectal Cancer
Laparoscopic Approach for Emergency Colon Resection
This is a randomized, controlled, parallel, multicenter trial to compare post-operative complications and long-term results between open and laparoscopic technique in emergency colorectal surgery.
- Conditions
- Laparoscopic Surgery, Colorectal Cancer, Colorectal Disorders, Emergencies
- Trial name
- NCT05005117
- Testing
- Laparoscopic operation, Open operation
- Where
- Finland
- Volunteers
- 192 people
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Rectal Cancer
A Randomized Controlled Clinical Trial Comparing Oncological Results and Functional Recovery Between Laparoscopic and Open Method for the Treatment of Advanced Rectal Cancer After Concurrent Chemoradiation Therapy (CCRT)
This is a three-year research project. The major aims of this study are to:(1) compare the functional recovery and oncologic results in patients with advance rectal cancer treated by either traditional open or laparoscopic…
- Trial name
- NCT00601549
- Testing
- Laparoscopic surgery, Traditional open surgery
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- National Taiwan University Hospital
Colonic Diseases, Rectal Diseases
Random Comparison of LigaSure and Disposable Staples for Laparoscopic Surgery
The purpose of this research is to compare two different standard of care surgical methods for the following large bowel (colon) procedures: laparoscopic right colectomy, total colectomy, and left colectomy.
- Trial name
- NCT00487409
- Testing
- Bipolar electrosurgical generator and instruments, Disposable stapling instruments
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University Hospitals Cleveland Medical Center
Colonic Neoplasms
Laparoscopic Surgery for T4 Tumor of the Colon Cancer (LST4C Trial)
The purpose of this study is to compare the short- and long-term survival of laparoscopic surgery and conventional open surgery for T4 colon cancer
- Trial name
- NCT03314896
- Testing
- Laparoscopic surgery
- Where
- China
- Volunteers
- 957 people
- Sponsor
- LI XIN-XIANG
Colorectal Cancer, ERAS
Hyper-ERAS Program for Highly Selective Colorectal Cancer Patients
This clinical trial aims to explore the safety and effectiveness of the Hyper-ERAS rehabilitation protocol for colorectal cancer patients and the feasibility of discharge within 48 hours.
- Trial name
- NCT06256315
- Testing
- Hyper-ERAS Program
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Peking University Cancer Hospital & Institute